IMP

Process View

Drosophila melanogaster

8 genes annotated in fly

central nervous system neuron differentiation

GO:0021953

The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "central nervous system neuron differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "central nervous system neuron differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
wg	wingless	0.939	Mouse
E(spl)	Enhancer of split	0.629	Rat
robo	roundabout	0.607	Human Zebrafish Mouse
shi	shibire	0.451
comm	commissureless	0.326
HLHmbeta	E(spl) region transcript mbeta	0.310	Rat
lea	leak	0.286	Human Zebrafish Mouse
HLHm7	E(spl) region transcript m7	0.274	Rat
mam	mastermind	0.242
ato	atonal	0.210
HGTX	CG13475 gene product from transcript CG13475-RB	0.195
NetB	Netrin-B	0.194	Zebrafish
HLHmgamma	E(spl) region transcript mgamma	0.142	Rat
gcm	glial cells missing	0.131
CtBP	C-terminal Binding Protein	0.129
lbl	ladybird late	0.119	Mouse
ptc	patched	0.116	Mouse
rap	retina aberrant in pattern	0.116
fra	frazzled	0.114	Mouse
slp1	sloppy paired 1	0.111
run	runt	0.111
N	Notch	0.106	Zebrafish
sim	single-minded	0.095
mid	midline	0.095
gsb	gooseberry	0.085	Mouse
ctp	cut up	0.080
SoxN	SoxNeuro	0.079	Mouse
elav	embryonic lethal abnormal vision	0.079
en	engrailed	0.078
ena	enabled	0.073
tup	tailup	0.072	Zebrafish Mouse
vvl	ventral veins lacking	0.070	Mouse
robo3	CG5423 gene product from transcript CG5423-RA	0.068	Human Zebrafish Mouse
ci	cubitus interruptus	0.064	Zebrafish Mouse
sc	scute	0.058	Human Mouse
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.052
slp2	sloppy paired 2	0.052	Mouse
InR	Insulin-like receptor	0.049	Zebrafish
Trim9	CG31721 gene product from transcript CG31721-RB	0.047
ac	achaete	0.046	Human Mouse
tutl	turtle	0.046
dock	dreadlocks	0.044
Antp	Antennapedia	0.044
Eph	Eph receptor tyrosine kinase	0.044	Mouse
Poxn	Pox neuro	0.043
hb	hunchback	0.042
gro	groucho	0.041
ash2	absent, small, or homeotic discs 2	0.039
pros	prospero	0.039	Zebrafish Mouse
sns	sticks and stones	0.038
CkIalpha	Casein kinase Ialpha	0.037
fas	faint sausage	0.034
ph-p	polyhomeotic proximal	0.034
hh	hedgehog	0.034
CycA	Cyclin A	0.033
HLHm3	E(spl) region transcript m3	0.033	Rat
tkv	thickveins	0.032
amos	absent MD neurons and olfactory sensilla	0.032
nkd	naked cuticle	0.031
jing	CG9397 gene product from transcript CG9397-RI	0.031
Ptp69D	Protein tyrosine phosphatase 69D	0.030
unc-5	CG8166 gene product from transcript CG8166-RA	0.030	Mouse
nub	nubbin	0.029
dsh	dishevelled	0.028
pdm2	POU domain protein 2	0.028
CadN	Cadherin-N	0.028
Wnt2	Wnt oncogene analog 2	0.026	Mouse
HLHm5	E(spl) region transcript m5	0.026	Rat
Ubx	Ultrabithorax	0.026
sli	slit	0.024	Human Zebrafish
Rab5	Rab-protein 5	0.024
salm	spalt major	0.024
btl	breathless	0.024	Mouse Rat
Ephrin	CG1862 gene product from transcript CG1862-RA	0.024
Syx1A	Syntaxin 1A	0.024
inv	invected	0.024	Fly
repo	reversed polarity	0.022
prd	paired	0.022	Mouse
kuz	kuzbanian	0.022
CG12424	CG12424 gene product from transcript CG12424-RC	0.022
l(2)k16918	lethal (2) k16918	0.022
sno	strawberry notch	0.021
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.021
dpn	deadpan	0.021
Taf1	TBP-associated factor 1	0.021
fz2	frizzled 2	0.021	Zebrafish
ed	echinoid	0.020
Dll	Distal-less	0.020	Mouse
Wnt5	Wnt oncogene analog 5	0.020
pygo	pygopus	0.020
hkb	huckebein	0.019
ey	eyeless	0.019	Mouse
ap	apterous	0.019
oc	ocelliless	0.019
brm	brahma	0.019
Galpha49B	G protein alpha49B	0.018	Mouse
pnt	pointed	0.018
sca	scabrous	0.018
dlg1	discs large 1	0.018
Ras85D	Ras oncogene at 85D	0.018
Caps	Calcium activated protein for secretion	0.017
sd	scalloped	0.017
malpha	E(spl) region transcript malpha	0.017
vnd	ventral nervous system defective	0.017
neuroligin	CG13772 gene product from transcript CG13772-RA	0.016
ss	spineless	0.016
stumps	CG31317 gene product from transcript CG31317-RC	0.016
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.016
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.016	Mouse
ems	empty spiracles	0.016	Zebrafish Mouse
ase	asense	0.015	Human Mouse
klu	klumpfuss	0.015
Fak56D	Focal Adhesion Kinase	0.015	Mouse
Ten-m	Tenascin major	0.015
beta-Spec	beta Spectrin	0.015
Cul-2	Cullin-2	0.015
HLHmdelta	E(spl) region transcript mdelta	0.014	Rat
Tollo	CG6890 gene product from transcript CG6890-RA	0.014
qm	quemao	0.014
sqz	squeeze	0.014
nerfin-1	nervous fingers 1	0.014
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.014
CkIIbeta	Casein kinase II beta subunit	0.014
Sra-1	specifically Rac1-associated protein 1	0.014
fng	fringe	0.013
crol	crooked legs	0.013
grn	grain	0.013	Zebrafish Mouse
trio	CG18214 gene product from transcript CG18214-RA	0.013
Egfr	Epidermal growth factor receptor	0.013	Mouse
twi	twist	0.013
m4	E(spl) region transcript m4	0.013
insc	inscuteable	0.012
eg	eagle	0.012
kni	knirps	0.012
ara	araucan	0.012
hiw	highwire	0.012	Mouse
Notum	CG13076 gene product from transcript CG13076-RB	0.012
lbe	ladybird early	0.012	Mouse
CG32635	CG32635 gene product from transcript CG32635-RA	0.011
TORC	CG6064 gene product from transcript CG6064-RA	0.011
spen	split ends	0.011
Alk	CG8250 gene product from transcript CG8250-RA	0.011
Myb	Myb oncogene-like	0.011
spi	spitz	0.011
tbce	tubulin-specific chaperone E	0.011
gsb-n	gooseberry-neuro	0.011	Mouse
beat-Ia	beaten path Ia	0.010
stai	stathmin	0.010
put	punt	0.010
rk	rickets	0.010
CG1024	CG1024 gene product from transcript CG1024-RB	0.010
pAbp	polyA-binding protein	0.010
futsch	CG34387 gene product from transcript CG34387-RC	0.010
wit	wishful thinking	0.010