IMP

Process View

Homo sapiens

27 genes annotated in human

cellular polysaccharide metabolic process

The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular polysaccharide metabolic process"

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Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.999	Yeast
INSR	insulin receptor	0.988
GRB10	growth factor receptor-bound protein 10	0.987	Rat
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.950
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.855
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.852
IRS1	insulin receptor substrate 1	0.782
IRS2	insulin receptor substrate 2	0.744
CREBBP	CREB binding protein	0.734
IGF1R	insulin-like growth factor 1 receptor	0.648	Human
CNTF	ciliary neurotrophic factor	0.575
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.489
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.453
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.429
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.427	Worm
NOXA1	NADPH oxidase activator 1	0.363
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.338
LZTS2	leucine zipper, putative tumor suppressor 2	0.324
RUNX1	runt-related transcription factor 1	0.304
AR	androgen receptor	0.274
RXRA	retinoid X receptor, alpha	0.260
HIPK2	homeodomain interacting protein kinase 2	0.243
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.241	Yeast
GSK3B	glycogen synthase kinase 3 beta	0.233
ITGB1BP3	integrin beta 1 binding protein 3	0.228
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.210	Yeast
RARA	retinoic acid receptor, alpha	0.188
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.169
NCOA1	nuclear receptor coactivator 1	0.160
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.159
GYS1	glycogen synthase 1 (muscle)	0.153
JAK2	Janus kinase 2	0.152
HYOU1	hypoxia up-regulated 1	0.150
SH3RF1	SH3 domain containing ring finger 1	0.145
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.141	Human
GYG1	glycogenin 1	0.141	Yeast
ATXN3	ataxin 3	0.140
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.139
KAT2B	K(lysine) acetyltransferase 2B	0.134
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.127
VCP	valosin containing protein	0.123
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.120
HR	hairless homolog (mouse)	0.111
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.111	Worm
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.105
NCF1	neutrophil cytosolic factor 1	0.100
DCAF7	DDB1 and CUL4 associated factor 7	0.100
CCND3	cyclin D3	0.099
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.094
FOXO1	forkhead box O1	0.093	Fly
RPTOR	regulatory associated protein of MTOR, complex 1	0.092
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.091
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.082
PICK1	protein interacting with PRKCA 1	0.082
INPPL1	inositol polyphosphate phosphatase-like 1	0.081
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.081
BTRC	beta-transducin repeat containing	0.080
GYG2	glycogenin 2	0.079	Yeast
PRKCB	protein kinase C, beta	0.079
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.079
FOXO3	forkhead box O3	0.079	Fly
CCND1	cyclin D1	0.073
RAB6A	RAB6A, member RAS oncogene family	0.072
SRP9	signal recognition particle 9kDa	0.072
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.071
STAT5B	signal transducer and activator of transcription 5B	0.068
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.068	Yeast
PPID	peptidylprolyl isomerase D	0.067
GCKR	glucokinase (hexokinase 4) regulator	0.066
OSBP	oxysterol binding protein	0.064
MED25	mediator complex subunit 25	0.062
NCOA2	nuclear receptor coactivator 2	0.059
HDAC3	histone deacetylase 3	0.059
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.058
FAF1	Fas (TNFRSF6) associated factor 1	0.055
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.054
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.053
IGF2R	insulin-like growth factor 2 receptor	0.053
NCOA6	nuclear receptor coactivator 6	0.052
FHL2	four and a half LIM domains 2	0.050
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.050
FBXW11	F-box and WD repeat domain containing 11	0.049
CREB1	cAMP responsive element binding protein 1	0.048
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.048
UBXN2A	UBX domain protein 2A	0.048
PDPK1	3-phosphoinositide dependent protein kinase-1	0.047
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.046
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.045
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.045
SREBF2	sterol regulatory element binding transcription factor 2	0.045
SMAD3	SMAD family member 3	0.045
RAB5A	RAB5A, member RAS oncogene family	0.045
CDCP1	CUB domain containing protein 1	0.044
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.044
SRSF5	serine/arginine-rich splicing factor 5	0.041
PILRA	paired immunoglobin-like type 2 receptor alpha	0.040
HNF4A	hepatocyte nuclear factor 4, alpha	0.040
CD2	CD2 molecule	0.040
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.038
AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	0.038
SORBS2	sorbin and SH3 domain containing 2	0.036
TRIM9	tripartite motif containing 9	0.035
SPRED1	sprouty-related, EVH1 domain containing 1	0.035
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.035
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.034
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.034
PRKCA	protein kinase C, alpha	0.033
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.033
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.032
FYN	FYN oncogene related to SRC, FGR, YES	0.032
NUMB	numb homolog (Drosophila)	0.032
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.032
SH2B1	SH2B adaptor protein 1	0.031
MAPT	microtubule-associated protein tau	0.030
CCL14	chemokine (C-C motif) ligand 14	0.029
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.029
PPP5C	protein phosphatase 5, catalytic subunit	0.028
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.028	Rat
CCND2	cyclin D2	0.028
ACACA	acetyl-CoA carboxylase alpha	0.028
PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.027
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.027
EP300	E1A binding protein p300	0.027
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.027
IGFBP5	insulin-like growth factor binding protein 5	0.027
GRB14	growth factor receptor-bound protein 14	0.026
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.025
SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.025
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.025
JUP	junction plakoglobin	0.025
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.024
TF	transferrin	0.024
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.024
SETDB1	SET domain, bifurcated 1	0.023
SESN2	sestrin 2	0.023
TNIK	TRAF2 and NCK interacting kinase	0.023
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.023
PRKCD	protein kinase C, delta	0.023	Human
GBAS	glioblastoma amplified sequence	0.022
PLD3	phospholipase D family, member 3	0.022
PRKCSH	protein kinase C substrate 80K-H	0.022
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.022
PKM2	pyruvate kinase, muscle	0.022
GYS2	glycogen synthase 2 (liver)	0.021
CLN3	ceroid-lipofuscinosis, neuronal 3	0.021
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.021
PSEN1	presenilin 1	0.021
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.021
RAB8A	RAB8A, member RAS oncogene family	0.021
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.021
GPI	glucose-6-phosphate isomerase	0.020
GLTPD1	glycolipid transfer protein domain containing 1	0.020
PFDN1	prefoldin subunit 1	0.020
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.020
IL6R	interleukin 6 receptor	0.020
HMOX2	heme oxygenase (decycling) 2	0.019
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.019
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.019
CYBA	cytochrome b-245, alpha polypeptide	0.019
NCOA3	nuclear receptor coactivator 3	0.019
HIC1	hypermethylated in cancer 1	0.019
MAPKAP1	mitogen-activated protein kinase associated protein 1	0.019
MAP2K5	mitogen-activated protein kinase kinase 5	0.018
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.018
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.018
EPOR	erythropoietin receptor	0.018
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.018
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.018
AZIN1	antizyme inhibitor 1	0.018
CARD11	caspase recruitment domain family, member 11	0.018
GOLGA8B	golgin A8 family, member B	0.017
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.017
SIRT2	sirtuin 2	0.017
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.017
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.017
TUBA1A	tubulin, alpha 1a	0.017
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.017
DCTN1	dynactin 1	0.017
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.016
ALAS1	aminolevulinate, delta-, synthase 1	0.016
GMCL1	germ cell-less homolog 1 (Drosophila)	0.016
PPARG	peroxisome proliferator-activated receptor gamma	0.016
LRRK2	leucine-rich repeat kinase 2	0.016
FNDC3B	fibronectin type III domain containing 3B	0.016
SYK	spleen tyrosine kinase	0.016
ADAP1	ArfGAP with dual PH domains 1	0.016
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.016
CD33	CD33 molecule	0.015
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.015
AXIN1	axin 1	0.015
STX16	syntaxin 16	0.015
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.015
WSB1	WD repeat and SOCS box containing 1	0.015
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.015
LMTK2	lemur tyrosine kinase 2	0.015
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.015
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.015
EMD	emerin	0.014
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.014
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.014
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.014
PPP4R1	protein phosphatase 4, regulatory subunit 1	0.014
SH2D2A	SH2 domain containing 2A	0.014
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.014	Rat
NOV	nephroblastoma overexpressed gene	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
CSAD	cysteine sulfinic acid decarboxylase	0.014
SAMD4B	sterile alpha motif domain containing 4B	0.013
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.013
SMAD2	SMAD family member 2	0.013
BCL10	B-cell CLL/lymphoma 10	0.013
PNPLA2	patatin-like phospholipase domain containing 2	0.013
DLG1	discs, large homolog 1 (Drosophila)	0.013
RAB14	RAB14, member RAS oncogene family	0.013
FKBP5	FK506 binding protein 5	0.013
TEF	thyrotrophic embryonic factor	0.013
APOA1	apolipoprotein A-I	0.013
PKP2	plakophilin 2	0.013
NRBP1	nuclear receptor binding protein 1	0.013
SDF4	stromal cell derived factor 4	0.013
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.013
CLTC	clathrin, heavy chain (Hc)	0.012
RFK	riboflavin kinase	0.012
ZNF431	zinc finger protein 431	0.012
CCHCR1	coiled-coil alpha-helical rod protein 1	0.012
FAM117B	family with sequence similarity 117, member B	0.012
ZMYM2	zinc finger, MYM-type 2	0.012
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.012
CAV1	caveolin 1, caveolae protein, 22kDa	0.012
HMGXB3	HMG box domain containing 3	0.012
CCNA1	cyclin A1	0.012
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.012
S100B	S100 calcium binding protein B	0.012
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.012
A1BG	alpha-1-B glycoprotein	0.012
NCL	nucleolin	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.012
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.012
PNMA1	paraneoplastic antigen MA1	0.011
ZFC3H1	zinc finger, C3H1-type containing	0.011
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.011
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.011
PYGM	phosphorylase, glycogen, muscle	0.011	Rat
PIM1	pim-1 oncogene	0.011	Yeast
SORBS1	sorbin and SH3 domain containing 1	0.011	Mouse
CCNE1	cyclin E1	0.011
RBM5	RNA binding motif protein 5	0.011
VHL	von Hippel-Lindau tumor suppressor	0.011
MAVS	mitochondrial antiviral signaling protein	0.011
TM9SF4	transmembrane 9 superfamily protein member 4	0.011
POFUT1	protein O-fucosyltransferase 1	0.011
LDLR	low density lipoprotein receptor	0.011
SGSH	N-sulfoglucosamine sulfohydrolase	0.011
GDI2	GDP dissociation inhibitor 2	0.011
GLIS2	GLIS family zinc finger 2	0.011
SPRR2A	small proline-rich protein 2A	0.011
FAM82A2	family with sequence similarity 82, member A2	0.011
TRIM32	tripartite motif containing 32	0.011
STAT2	signal transducer and activator of transcription 2, 113kDa	0.011
ACVR1B	activin A receptor, type IB	0.011
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.011
RAB10	RAB10, member RAS oncogene family	0.011
CDK6	cyclin-dependent kinase 6	0.011
CTNNBIP1	catenin, beta interacting protein 1	0.011
S100A1	S100 calcium binding protein A1	0.011
CCDC115	coiled-coil domain containing 115	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
HOXD8	homeobox D8	0.011
BMX	BMX non-receptor tyrosine kinase	0.011
FHOD3	formin homology 2 domain containing 3	0.011
CPD	carboxypeptidase D	0.011
COL4A5	collagen, type IV, alpha 5	0.011
PHKB	phosphorylase kinase, beta	0.010
HDAC5	histone deacetylase 5	0.010
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.010
BAIAP2	BAI1-associated protein 2	0.010
KIF1C	kinesin family member 1C	0.010
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.010
PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	0.010
NCOR2	nuclear receptor corepressor 2	0.010