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Homo sapiens

18 genes annotated in human

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regulation of blood vessel size

GO:0050880

Any process that modulates the size of blood vessels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of blood vessel size"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of blood vessel size" (in gray)

Name	Description	Probability	Func Analog Organism
TEK	TEK tyrosine kinase, endothelial	0.995
PTEN	phosphatase and tensin homolog	0.944
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.918
FGA	fibrinogen alpha chain	0.905
PRKG1	protein kinase, cGMP-dependent, type I	0.884	Mouse
NOTCH1	notch 1	0.831
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.827
FGB	fibrinogen beta chain	0.783
DRD2	dopamine receptor D2	0.769
NOSTRIN	nitric oxide synthase trafficker	0.719
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.658
ACTN2	actinin, alpha 2	0.624
CAV2	caveolin 2	0.616
A2M	alpha-2-macroglobulin	0.601
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.568
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.511
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.501
MAPK12	mitogen-activated protein kinase 12	0.500
COTL1	coactosin-like 1 (Dictyostelium)	0.437
MPDZ	multiple PDZ domain protein	0.431
RLN3	relaxin 3	0.416
TIMP3	TIMP metallopeptidase inhibitor 3	0.416
FGG	fibrinogen gamma chain	0.399
IL8	interleukin 8	0.392
PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	0.354
JAG1	jagged 1	0.338
NAMPT	nicotinamide phosphoribosyltransferase	0.326
BCAR1	breast cancer anti-estrogen resistance 1	0.306
GCLC	glutamate-cysteine ligase, catalytic subunit	0.263
GCLM	glutamate-cysteine ligase, modifier subunit	0.241
CRP	C-reactive protein, pentraxin-related	0.240
VAC14	Vac14 homolog (S. cerevisiae)	0.224
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.196
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.189
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.177
CRELD2	cysteine-rich with EGF-like domains 2	0.173
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.144
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.140
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.133	Mouse
FAS	Fas (TNF receptor superfamily, member 6)	0.133
ALB	albumin	0.118
TBC1D10A	TBC1 domain family, member 10A	0.116
EGFR	epidermal growth factor receptor	0.107
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.105
TIMP2	TIMP metallopeptidase inhibitor 2	0.105
ADORA1	adenosine A1 receptor	0.093	Rat
ADORA2A	adenosine A2a receptor	0.084	Rat
PEBP4	phosphatidylethanolamine-binding protein 4	0.077
THBS2	thrombospondin 2	0.076
RB1	retinoblastoma 1	0.074
MYH11	myosin, heavy chain 11, smooth muscle	0.073
HP	haptoglobin	0.072
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.072
ADAM15	ADAM metallopeptidase domain 15	0.070
CDH5	cadherin 5, type 2 (vascular endothelium)	0.069
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.063
CYSLTR2	cysteinyl leukotriene receptor 2	0.062
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.061
TECPR1	tectonin beta-propeller repeat containing 1	0.057
SSTR3	somatostatin receptor 3	0.055
NFIL3	nuclear factor, interleukin 3 regulated	0.055
LRP1	low density lipoprotein receptor-related protein 1	0.053
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.050
FYB	FYN binding protein	0.050
CALCRL	calcitonin receptor-like	0.050
KAT2B	K(lysine) acetyltransferase 2B	0.049
LMNA	lamin A/C	0.048
NCOA6	nuclear receptor coactivator 6	0.048
ACVR1	activin A receptor, type I	0.044
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.042
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.042
PXN	paxillin	0.040
MAPT	microtubule-associated protein tau	0.039
MYOZ1	myozenin 1	0.038
DDR2	discoidin domain receptor tyrosine kinase 2	0.037
F2	coagulation factor II (thrombin)	0.036
TKT	transketolase	0.036
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.036
ADRB2	adrenergic, beta-2-, receptor, surface	0.035	Human Mouse Rat
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.034
SDPR	serum deprivation response	0.033
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.033
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.032
RET	ret proto-oncogene	0.032
APOC1	apolipoprotein C-I	0.032
MYH9	myosin, heavy chain 9, non-muscle	0.031
SDF2L1	stromal cell-derived factor 2-like 1	0.031
BBS10	Bardet-Biedl syndrome 10	0.031
GLRX3	glutaredoxin 3	0.031
TP73	tumor protein p73	0.030
BAG1	BCL2-associated athanogene	0.030
HYOU1	hypoxia up-regulated 1	0.030
IGF1	insulin-like growth factor 1 (somatomedin C)	0.030
MAPK8	mitogen-activated protein kinase 8	0.030
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.029
EGLN3	egl nine homolog 3 (C. elegans)	0.028
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.028
PROCR	protein C receptor, endothelial	0.028
ENG	endoglin	0.027
PRKCDBP	protein kinase C, delta binding protein	0.027
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.027
PTPRF	protein tyrosine phosphatase, receptor type, F	0.027
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.027
CD34	CD34 molecule	0.026
DLG4	discs, large homolog 4 (Drosophila)	0.026
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.025	Rat
FRZB	frizzled-related protein	0.025
EZR	ezrin	0.025
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.024
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.024
RHEB	Ras homolog enriched in brain	0.023
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.023	Rat
RIN3	Ras and Rab interactor 3	0.023
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.022
TXNRD1	thioredoxin reductase 1	0.022
LAT	linker for activation of T cells	0.022
EDNRB	endothelin receptor type B	0.022
PLG	plasminogen	0.021
ARRDC3	arrestin domain containing 3	0.021
ANGPTL4	angiopoietin-like 4	0.021	Human
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.021
SYK	spleen tyrosine kinase	0.020
THBS1	thrombospondin 1	0.020
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.019
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.019
SPARCL1	SPARC-like 1 (hevin)	0.019
GCH1	GTP cyclohydrolase 1	0.019
KRT5	keratin 5	0.019
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.018	Human
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.018
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.017
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.017	Rat
PRKCG	protein kinase C, gamma	0.017
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.017
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.017
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.017	Human
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.017
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.016
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.016
KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.016
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.016
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.016
MED28	mediator complex subunit 28	0.016
APOA1	apolipoprotein A-I	0.016
CD247	CD247 molecule	0.016
CUX1	cut-like homeobox 1	0.016
AGTR1	angiotensin II receptor, type 1	0.015
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.015
RADIL	Ras association and DIL domains	0.015
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.015
EDN1	endothelin 1	0.015
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.015
HSPB1	heat shock 27kDa protein 1	0.015
LAMA4	laminin, alpha 4	0.015
ANGPT1	angiopoietin 1	0.014	Human
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.014
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.014
BMPR1A	bone morphogenetic protein receptor, type IA	0.014
MRVI1	murine retrovirus integration site 1 homolog	0.014	Mouse
SPRR2A	small proline-rich protein 2A	0.014
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.014
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.014
STAB1	stabilin 1	0.014
MSH4	mutS homolog 4 (E. coli)	0.014
ELN	elastin	0.014
EPS8	epidermal growth factor receptor pathway substrate 8	0.014
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.014
GAB2	GRB2-associated binding protein 2	0.013
APOE	apolipoprotein E	0.013	Mouse
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.013
NCOA7	nuclear receptor coactivator 7	0.013
DLC1	deleted in liver cancer 1	0.013
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.013
VEGFC	vascular endothelial growth factor C	0.013
GJA1	gap junction protein, alpha 1, 43kDa	0.013
C19orf10	chromosome 19 open reading frame 10	0.013
WFDC1	WAP four-disulfide core domain 1	0.013
IL6	interleukin 6 (interferon, beta 2)	0.013
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.013
MAPK3	mitogen-activated protein kinase 3	0.013
HSPB6	heat shock protein, alpha-crystallin-related, B6	0.013
CNN2	calponin 2	0.013
PDIA4	protein disulfide isomerase family A, member 4	0.012
CCL7	chemokine (C-C motif) ligand 7	0.012
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.012
PLTP	phospholipid transfer protein	0.012
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.012
AQP7	aquaporin 7	0.012
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.012	Mouse Rat
CD93	CD93 molecule	0.012
IL1B	interleukin 1, beta	0.012
IGFBP1	insulin-like growth factor binding protein 1	0.012
ALOX5AP	arachidonate 5-lipoxygenase-activating protein	0.012
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.012
PLAUR	plasminogen activator, urokinase receptor	0.012
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.012
CTSB	cathepsin B	0.012
CSF1R	colony stimulating factor 1 receptor	0.012
THBD	thrombomodulin	0.012
AMBP	alpha-1-microglobulin/bikunin precursor	0.012
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.012
TAC1	tachykinin, precursor 1	0.012
SORBS1	sorbin and SH3 domain containing 1	0.012
MNDA	myeloid cell nuclear differentiation antigen	0.012
NID2	nidogen 2 (osteonidogen)	0.011
PDIA6	protein disulfide isomerase family A, member 6	0.011
ITGB5	integrin, beta 5	0.011
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.011
DUSP6	dual specificity phosphatase 6	0.011
PROL1	proline rich, lacrimal 1	0.011
COL4A1	collagen, type IV, alpha 1	0.011
ITIH3	inter-alpha (globulin) inhibitor H3	0.011
FAF1	Fas (TNFRSF6) associated factor 1	0.011
TEF	thyrotrophic embryonic factor	0.011
TNXB	tenascin XB	0.011
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.011
DPT	dermatopontin	0.011
NPY5R	neuropeptide Y receptor Y5	0.011
PZP	pregnancy-zone protein	0.011
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.011
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
TGFB3	transforming growth factor, beta 3	0.011
NDRG1	N-myc downstream regulated 1	0.011
BDKRB2	bradykinin receptor B2	0.011	Human Mouse
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.011
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.011
COL18A1	collagen, type XVIII, alpha 1	0.011
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.011
ANGPT2	angiopoietin 2	0.011	Human
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.011
NOTCH4	notch 4	0.010
CLCN3	chloride channel 3	0.010
RGS2	regulator of G-protein signaling 2, 24kDa	0.010	Mouse
CFHR2	complement factor H-related 2	0.010
GRB7	growth factor receptor-bound protein 7	0.010
NOS3	nitric oxide synthase 3 (endothelial cell)	0.010	Human
CRHBP	corticotropin releasing hormone binding protein	0.010
RGS5	regulator of G-protein signaling 5	0.010
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.010