IMP

Process View

Homo sapiens

20 genes annotated in human

response to nutrient

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to nutrient"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to nutrient" (in gray)

Name	Description	Probability	Func Analog Organism
ESR1	estrogen receptor 1	0.651
NCOR2	nuclear receptor corepressor 2	0.564
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.495	Human
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.432	Human
RXRA	retinoid X receptor, alpha	0.428	Rat
HNF4A	hepatocyte nuclear factor 4, alpha	0.413
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.404
THBS1	thrombospondin 1	0.386
CDK6	cyclin-dependent kinase 6	0.383
RARA	retinoic acid receptor, alpha	0.339	Rat
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.335
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.331	Rat
NFYA	nuclear transcription factor Y, alpha	0.292
COTL1	coactosin-like 1 (Dictyostelium)	0.258
NRP1	neuropilin 1	0.244
DLG4	discs, large homolog 4 (Drosophila)	0.241
CCND3	cyclin D3	0.225
ENG	endoglin	0.222
TP53	tumor protein p53	0.192	Rat
MED13	mediator complex subunit 13	0.167
NCOA1	nuclear receptor coactivator 1	0.161
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.159	Rat
IL1R1	interleukin 1 receptor, type I	0.158
ACTN2	actinin, alpha 2	0.137
CCND1	cyclin D1	0.133	Rat
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.133
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.131
MED10	mediator complex subunit 10	0.122
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.117
EP300	E1A binding protein p300	0.117
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.116
AXL	AXL receptor tyrosine kinase	0.108
GSK3B	glycogen synthase kinase 3 beta	0.106
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.106
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.102
TSC1	tuberous sclerosis 1	0.099	Fly
RB1	retinoblastoma 1	0.098
DHCR7	7-dehydrocholesterol reductase	0.096
TSC2	tuberous sclerosis 2	0.092	Fly
PPARA	peroxisome proliferator-activated receptor alpha	0.090	Human
MED25	mediator complex subunit 25	0.088
PRSS2	protease, serine, 2 (trypsin 2)	0.077
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.075
NRIP1	nuclear receptor interacting protein 1	0.069
ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	0.068
SIRT1	sirtuin 1	0.063	Fly
FN1	fibronectin 1	0.062
CCR5	chemokine (C-C motif) receptor 5	0.061
CXCL11	chemokine (C-X-C motif) ligand 11	0.060
DDIT3	DNA-damage-inducible transcript 3	0.060	Rat
AR	androgen receptor	0.058
EGFR	epidermal growth factor receptor	0.056
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.056	Rat
TEK	TEK tyrosine kinase, endothelial	0.054
VEGFA	vascular endothelial growth factor A	0.054	Rat
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.052
DNM2	dynamin 2	0.051	Fly
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.049	Rat
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.048	Fly
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.047	Rat
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.046
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.045
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.045	Fly
FSTL1	follistatin-like 1	0.044
COL3A1	collagen, type III, alpha 1	0.043
VAC14	Vac14 homolog (S. cerevisiae)	0.043
ITGB4	integrin, beta 4	0.042
NCOA3	nuclear receptor coactivator 3	0.042	Human
FADS2	fatty acid desaturase 2	0.041
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.041
NCOR1	nuclear receptor corepressor 1	0.041
SP1	Sp1 transcription factor	0.040
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.040
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.040	Rat
ESR2	estrogen receptor 2 (ER beta)	0.040
CAV1	caveolin 1, caveolae protein, 22kDa	0.040
EPAS1	endothelial PAS domain protein 1	0.039
HDAC1	histone deacetylase 1	0.039
IRS1	insulin receptor substrate 1	0.039
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.038
OSMR	oncostatin M receptor	0.037
DBP	D site of albumin promoter (albumin D-box) binding protein	0.037	Fly
IQGAP1	IQ motif containing GTPase activating protein 1	0.037
RALBP1	ralA binding protein 1	0.037
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.037	Rat
ELL	elongation factor RNA polymerase II	0.037
IRS2	insulin receptor substrate 2	0.036
IL1RN	interleukin 1 receptor antagonist	0.034
ENO2	enolase 2 (gamma, neuronal)	0.033
MSN	moesin	0.032
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.032	Yeast
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.031
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.030
SPRR2A	small proline-rich protein 2A	0.029
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.028
FOXO1	forkhead box O1	0.028
GRB10	growth factor receptor-bound protein 10	0.028
TGFB3	transforming growth factor, beta 3	0.027
PDPK1	3-phosphoinositide dependent protein kinase-1	0.027
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.027
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.027
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.027	Rat
RUNX1	runt-related transcription factor 1	0.026
S100B	S100 calcium binding protein B	0.026
FBXW7	F-box and WD repeat domain containing 7	0.026
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.026
INO80B	INO80 complex subunit B	0.026
UBQLN1	ubiquilin 1	0.026
SC4MOL	sterol-C4-methyl oxidase-like	0.025
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.025
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.025
RIPK2	receptor-interacting serine-threonine kinase 2	0.025
LRRK2	leucine-rich repeat kinase 2	0.025
WNT3A	wingless-type MMTV integration site family, member 3A	0.024
KAT2B	K(lysine) acetyltransferase 2B	0.024
MED1	mediator complex subunit 1	0.024	Mouse
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.023
ALB	albumin	0.023
MKL1	megakaryoblastic leukemia (translocation) 1	0.023
AMPH	amphiphysin	0.023
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.023
BCL2L1	BCL2-like 1	0.022
IL1RAP	interleukin 1 receptor accessory protein	0.022
MED13L	mediator complex subunit 13-like	0.022
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.021
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.021	Rat
PGR	progesterone receptor	0.021
ACACA	acetyl-CoA carboxylase alpha	0.021
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.021
CDK8	cyclin-dependent kinase 8	0.021	Yeast
APIP	APAF1 interacting protein	0.021
SETDB1	SET domain, bifurcated 1	0.021
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.021
VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)	0.020
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.020
TGFB1	transforming growth factor, beta 1	0.020	Rat
USF1	upstream transcription factor 1	0.020
COL1A2	collagen, type I, alpha 2	0.020
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.020
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.019
CD63	CD63 molecule	0.019
CHMP4B	chromatin modifying protein 4B	0.019
WASL	Wiskott-Aldrich syndrome-like	0.019
HLF	hepatic leukemia factor	0.019
HRG	histidine-rich glycoprotein	0.019
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.019
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.018	Human
INSR	insulin receptor	0.018	Rat
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.018	Rat
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.018
IL8	interleukin 8	0.018
AGTR2	angiotensin II receptor, type 2	0.018
ESRRG	estrogen-related receptor gamma	0.018
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.018	Rat
MASP2	mannan-binding lectin serine peptidase 2	0.017
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
KNG1	kininogen 1	0.017
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.017
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.017
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.017
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.016
ADAM15	ADAM metallopeptidase domain 15	0.016
LEPR	leptin receptor	0.016
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.016
GCKR	glucokinase (hexokinase 4) regulator	0.016
WNT5A	wingless-type MMTV integration site family, member 5A	0.016
EGR1	early growth response 1	0.016
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.015
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.015
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.015
ITGA6	integrin, alpha 6	0.015
COL4A1	collagen, type IV, alpha 1	0.015
F9	coagulation factor IX	0.015
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.015
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.015
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.015
JAK1	Janus kinase 1	0.015
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.015
PAWR	PRKC, apoptosis, WT1, regulator	0.015
TK1	thymidine kinase 1, soluble	0.015
TBX5	T-box 5	0.015
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.014	Rat
C8A	complement component 8, alpha polypeptide	0.014
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.014
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.014
AHSG	alpha-2-HS-glycoprotein	0.014
KRT15	keratin 15	0.014
SMAD9	SMAD family member 9	0.014
MED29	mediator complex subunit 29	0.014
FDPS	farnesyl diphosphate synthase	0.014
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.014	Yeast
CDK2	cyclin-dependent kinase 2	0.014
SPOP	speckle-type POZ protein	0.014
ZHX1	zinc fingers and homeoboxes 1	0.014
MED14	mediator complex subunit 14	0.014
TF	transferrin	0.013
TRIM27	tripartite motif containing 27	0.013
USF2	upstream transcription factor 2, c-fos interacting	0.013
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.013
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.013
IDI1	isopentenyl-diphosphate delta isomerase 1	0.013
AQP7	aquaporin 7	0.013
ALDOB	aldolase B, fructose-bisphosphate	0.013
EBP	emopamil binding protein (sterol isomerase)	0.013
ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.013
SQLE	squalene epoxidase	0.013
MEP1B	meprin A, beta	0.012
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.012
APOB	apolipoprotein B (including Ag(x) antigen)	0.012
EZR	ezrin	0.012
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.012
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.012
FKBP8	FK506 binding protein 8, 38kDa	0.012
INSIG1	insulin induced gene 1	0.012
CDHR5	cadherin-related family member 5	0.012
FGA	fibrinogen alpha chain	0.012
VPS25	vacuolar protein sorting 25 homolog (S. cerevisiae)	0.012	Yeast
MYOCD	myocardin	0.012
BMP2	bone morphogenetic protein 2	0.012
CCL20	chemokine (C-C motif) ligand 20	0.012
COL5A2	collagen, type V, alpha 2	0.012
F11	coagulation factor XI	0.012
MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.011
ADH6	alcohol dehydrogenase 6 (class V)	0.011
FABP4	fatty acid binding protein 4, adipocyte	0.011	Zebrafish
CCL2	chemokine (C-C motif) ligand 2	0.011
PDLIM7	PDZ and LIM domain 7 (enigma)	0.011
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.011
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.011
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.011
APOA2	apolipoprotein A-II	0.011
VCAM1	vascular cell adhesion molecule 1	0.011	Rat
PTK2	PTK2 protein tyrosine kinase 2	0.011
SHARPIN	SHANK-associated RH domain interactor	0.011
AKAP6	A kinase (PRKA) anchor protein 6	0.011
GAB2	GRB2-associated binding protein 2	0.011
APP	amyloid beta (A4) precursor protein	0.011
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.011
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.011	Yeast
BCL2A1	BCL2-related protein A1	0.011
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.010
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.010
F3	coagulation factor III (thromboplastin, tissue factor)	0.010
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.010
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.010
CXCL9	chemokine (C-X-C motif) ligand 9	0.010
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.010
AMBRA1	autophagy/beclin-1 regulator 1	0.010
APCS	amyloid P component, serum	0.010
PAH	phenylalanine hydroxylase	0.010
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.010
CHMP6	chromatin modifying protein 6	0.010
ANGPT2	angiopoietin 2	0.010