IMP

Process View

Homo sapiens

14 genes annotated in human

neuron projection extension

GO:1990138

Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neuron projection extension"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neuron projection extension" (in gray)

Name	Description	Probability	Func Analog Organism
MAPK8	mitogen-activated protein kinase 8	0.958	Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.919
FGF1	fibroblast growth factor 1 (acidic)	0.855	Worm
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.816	Worm Fly
MPRIP	myosin phosphatase Rho interacting protein	0.712
MAP2K4	mitogen-activated protein kinase kinase 4	0.710
FGFR1	fibroblast growth factor receptor 1	0.630	Fly
FLNA	filamin A, alpha	0.541
NRP1	neuropilin 1	0.527	Zebrafish Mouse Rat
ACTN2	actinin, alpha 2	0.417
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.340
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.305
LRRK2	leucine-rich repeat kinase 2	0.291	Worm
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.283	Fly
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.273
APC	adenomatous polyposis coli	0.235
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.235
FMR1	fragile X mental retardation 1	0.219
DLG4	discs, large homolog 4 (Drosophila)	0.188
NCKAP1	NCK-associated protein 1	0.184
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.146	Rat
FN1	fibronectin 1	0.115	Mouse
FGFR2	fibroblast growth factor receptor 2	0.112	Fly
JUN	jun proto-oncogene	0.111
ARRB1	arrestin, beta 1	0.108
PLXND1	plexin D1	0.082
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.075
VEGFA	vascular endothelial growth factor A	0.070	Mouse
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.070
LRP6	low density lipoprotein receptor-related protein 6	0.067
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.062
GRB7	growth factor receptor-bound protein 7	0.060
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.059	Mouse
ADAM19	ADAM metallopeptidase domain 19	0.058
ATF2	activating transcription factor 2	0.058
ITGB4	integrin, beta 4	0.053
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.052	Mouse
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.049
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.048
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.046
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.046
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.045
TGFB3	transforming growth factor, beta 3	0.043
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.042
GAS7	growth arrest-specific 7	0.042
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.041
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.041
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.040	Fly
PFN1	profilin 1	0.040
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.040
MAPT	microtubule-associated protein tau	0.038
DDX20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	0.038
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.038
MAP1B	microtubule-associated protein 1B	0.038	Mouse
GBP3	guanylate binding protein 3	0.037
TTR	transthyretin	0.037
GABARAP	GABA(A) receptor-associated protein	0.036
ABI2	abl-interactor 2	0.036	Fly
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.035	Fly
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.035	Fly
STRADA	STE20-related kinase adaptor alpha	0.035
MKL1	megakaryoblastic leukemia (translocation) 1	0.034
RANBP2	RAN binding protein 2	0.034
DISC1	disrupted in schizophrenia 1	0.034
VIM	vimentin	0.034
CBX6	chromobox homolog 6	0.033
FGF2	fibroblast growth factor 2 (basic)	0.033	Worm
SORBS1	sorbin and SH3 domain containing 1	0.033
HSPG2	heparan sulfate proteoglycan 2	0.033
PTCH1	patched 1	0.032
PCGF2	polycomb group ring finger 2	0.032
NPTN	neuroplastin	0.032
AGTPBP1	ATP/GTP binding protein 1	0.029
NCF2	neutrophil cytosolic factor 2	0.028
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.027
SCHIP1	schwannomin interacting protein 1	0.027
MARK4	MAP/microtubule affinity-regulating kinase 4	0.026
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.026
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.026
FZD1	frizzled homolog 1 (Drosophila)	0.026
CLIP1	CAP-GLY domain containing linker protein 1	0.025
SESN2	sestrin 2	0.025
ATF7IP	activating transcription factor 7 interacting protein	0.025
ZNF512B	zinc finger protein 512B	0.025
CDK9	cyclin-dependent kinase 9	0.025
CBX8	chromobox homolog 8	0.025
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.024
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.024
SPTBN1	spectrin, beta, non-erythrocytic 1	0.024
MYOD1	myogenic differentiation 1	0.023
DCC	deleted in colorectal carcinoma	0.023
CLASP1	cytoplasmic linker associated protein 1	0.023
SORBS2	sorbin and SH3 domain containing 2	0.023
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.023
TCF4	transcription factor 4	0.023
CTSA	cathepsin A	0.023
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.023	Mouse Fly
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.022
LAMA4	laminin, alpha 4	0.022
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.021
PRKG1	protein kinase, cGMP-dependent, type I	0.021
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.021
ANK2	ankyrin 2, neuronal	0.020
CSNK1E	casein kinase 1, epsilon	0.020
RNF2	ring finger protein 2	0.020
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.019
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.019
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.019
MAPK9	mitogen-activated protein kinase 9	0.019	Fly
FAM190B	family with sequence similarity 190, member B	0.019
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.019
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.019
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.019
CSNK1A1	casein kinase 1, alpha 1	0.019
SLIT2	slit homolog 2 (Drosophila)	0.018
FGFR3	fibroblast growth factor receptor 3	0.018	Fly
FERMT2	fermitin family member 2	0.018
FGF7	fibroblast growth factor 7	0.018
CFL1	cofilin 1 (non-muscle)	0.018
CPE	carboxypeptidase E	0.018
CNOT6	CCR4-NOT transcription complex, subunit 6	0.018
MYBBP1A	MYB binding protein (P160) 1a	0.018
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.018
QKI	quaking homolog, KH domain RNA binding (mouse)	0.017
ENG	endoglin	0.017
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.017
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.017
UNC119	unc-119 homolog (C. elegans)	0.017
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.017
ATXN1	ataxin 1	0.016
KIF5B	kinesin family member 5B	0.016
MAP2K7	mitogen-activated protein kinase kinase 7	0.016	Fly
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.016
TRIP6	thyroid hormone receptor interactor 6	0.015
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.015
RBL1	retinoblastoma-like 1 (p107)	0.015
MYOCD	myocardin	0.014
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.014
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.014
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.014
WASF1	WAS protein family, member 1	0.014	Fly
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.014
PRMT1	protein arginine methyltransferase 1	0.014
NF2	neurofibromin 2 (merlin)	0.014
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.014	Human
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.014
FBXO7	F-box protein 7	0.014
MARK2	MAP/microtubule affinity-regulating kinase 2	0.014
NRXN1	neurexin 1	0.014
SMAD9	SMAD family member 9	0.014
ZNF746	zinc finger protein 746	0.014
ATN1	atrophin 1	0.014
MBIP	MAP3K12 binding inhibitory protein 1	0.014
ESR1	estrogen receptor 1	0.013
SPAG9	sperm associated antigen 9	0.013
TUBA1A	tubulin, alpha 1a	0.013
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.013
BBS10	Bardet-Biedl syndrome 10	0.013
RBBP7	retinoblastoma binding protein 7	0.013
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.013
MYOG	myogenin (myogenic factor 4)	0.013
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.013
LARP7	La ribonucleoprotein domain family, member 7	0.013
NGFR	nerve growth factor receptor	0.013
AGRN	agrin	0.013
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.013
PARVA	parvin, alpha	0.012
CAB39	calcium binding protein 39	0.012
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.012
DMPK	dystrophia myotonica-protein kinase	0.012
NCOR2	nuclear receptor corepressor 2	0.012
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.012
RING1	ring finger protein 1	0.012
MARK3	MAP/microtubule affinity-regulating kinase 3	0.012
RAB5A	RAB5A, member RAS oncogene family	0.012
DCLK1	doublecortin-like kinase 1	0.012	Mouse
PUM2	pumilio homolog 2 (Drosophila)	0.012
CTGF	connective tissue growth factor	0.012
NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	0.012
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.012
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.011
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.011
FGF10	fibroblast growth factor 10	0.011
BSN	bassoon (presynaptic cytomatrix protein)	0.011
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.011	Human
JAG2	jagged 2	0.011
SFRP1	secreted frizzled-related protein 1	0.011
CDK5	cyclin-dependent kinase 5	0.011	Mouse
MAP1A	microtubule-associated protein 1A	0.011
CEP164	centrosomal protein 164kDa	0.011
NCAN	neurocan	0.010
SORBS3	sorbin and SH3 domain containing 3	0.010
MYH9	myosin, heavy chain 9, non-muscle	0.010
PLCG1	phospholipase C, gamma 1	0.010
NFASC	neurofascin	0.010
MYH10	myosin, heavy chain 10, non-muscle	0.010
MACF1	microtubule-actin crosslinking factor 1	0.010	Fly
PCDH17	protocadherin 17	0.010
VHL	von Hippel-Lindau tumor suppressor	0.010
TGFB2	transforming growth factor, beta 2	0.010
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.010	Mouse
FAM160A2	family with sequence similarity 160, member A2	0.010
LTBP4	latent transforming growth factor beta binding protein 4	0.010
BAIAP2	BAI1-associated protein 2	0.010
FBLN1	fibulin 1	0.010