IMP

Process View

Mus musculus

16 genes annotated in mouse

Multi-species View

regulation of mast cell degranulation

GO:0043304

Any process that modulates the frequency, rate, or extent of mast cell degranulation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mast cell degranulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mast cell degranulation" (in gray)

Name	Description	Probability	Func Analog Organism
Inpp5d	inositol polyphosphate-5-phosphatase D	0.992
Grb2	growth factor receptor bound protein 2	0.979
Il4	interleukin 4	0.974
Cd247	CD247 antigen	0.965	Mouse
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.951
Mefv	Mediterranean fever	0.910
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.857
Ptprc	protein tyrosine phosphatase, receptor type, C	0.856
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.761
Ikzf1	IKAROS family zinc finger 1	0.735
Lat	linker for activation of T cells	0.721
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.620
Cd19	CD19 antigen	0.591
Ifng	interferon gamma	0.495
Dok1	docking protein 1	0.488
Cbl	Casitas B-lineage lymphoma	0.485
Dok3	docking protein 3	0.426
Ptk2	PTK2 protein tyrosine kinase 2	0.402
Cd40	CD40 antigen	0.352
Igh	immunoglobulin heavy chain complex	0.323
Nfam1	Nfat activating molecule with ITAM motif 1	0.314
C5ar1	complement component 5a receptor 1	0.276
Cd22	CD22 antigen	0.274
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.239
Clec4n	C-type lectin domain family 4, member n	0.221
Msr1	macrophage scavenger receptor 1	0.217
Met	met proto-oncogene	0.188
Btk	Bruton agammaglobulinemia tyrosine kinase	0.175	Mouse
Il2rb	interleukin 2 receptor, beta chain	0.165
Il2	interleukin 2	0.161
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.157
Shc1	src homology 2 domain-containing transforming protein C1	0.148
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.139
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.130
Hcst	hematopoietic cell signal transducer	0.130
Lck	lymphocyte protein tyrosine kinase	0.130	Mouse
Tcra	T-cell receptor alpha chain	0.126
Was	Wiskott-Aldrich syndrome homolog (human)	0.121
S1pr4	sphingosine-1-phosphate receptor 4	0.116
Tyrobp	TYRO protein tyrosine kinase binding protein	0.113
Snai1	snail homolog 1 (Drosophila)	0.110
Clec4d	C-type lectin domain family 4, member d	0.107
Lyl1	lymphoblastomic leukemia 1	0.106
Sykb	spleen tyrosine kinase	0.103
Rag1	recombination activating gene 1	0.100
Foxn1	forkhead box N1	0.100
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.091	Mouse
Plcg2	phospholipase C, gamma 2	0.088
Cd4	CD4 antigen	0.087
Stat6	signal transducer and activator of transcription 6	0.085
Il2rg	interleukin 2 receptor, gamma chain	0.082
Dok2	docking protein 2	0.082
Lair1	leukocyte-associated Ig-like receptor 1	0.082
Trem3	triggering receptor expressed on myeloid cells 3	0.077
Fes	feline sarcoma oncogene	0.076	Human
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.076
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.074
Tbxas1	thromboxane A synthase 1, platelet	0.071
Itgb3	integrin beta 3	0.069
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.066
Fas	Fas (TNF receptor superfamily member 6)	0.066
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.066	Mouse
Kit	kit oncogene	0.065
Ccr1	chemokine (C-C motif) receptor 1	0.064
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.063
Ccr6	chemokine (C-C motif) receptor 6	0.062
Il10ra	interleukin 10 receptor, alpha	0.062
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.057
Pilra	paired immunoglobin-like type 2 receptor alpha	0.057
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.055	Mouse
Pten	phosphatase and tensin homolog	0.055
Il13	interleukin 13	0.052
Il4ra	interleukin 4 receptor, alpha	0.050
Mmp8	matrix metallopeptidase 8	0.050
Hmox1	heme oxygenase (decycling) 1	0.048
Slpi	secretory leukocyte peptidase inhibitor	0.048
Siglece	sialic acid binding Ig-like lectin E	0.045
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.044
Nos2	nitric oxide synthase 2, inducible	0.043
Csf1r	colony stimulating factor 1 receptor	0.043
Pxn	paxillin	0.042
Plcg1	phospholipase C, gamma 1	0.041
Ptgs2	prostaglandin-endoperoxide synthase 2	0.041
Mvp	major vault protein	0.041
Cmklr1	chemokine-like receptor 1	0.041
Irg1	immunoresponsive gene 1	0.041
Zap70	zeta-chain (TCR) associated protein kinase	0.039	Mouse
Cxcr2	chemokine (C-X-C motif) receptor 2	0.038
Il1rn	interleukin 1 receptor antagonist	0.038
Cd28	CD28 antigen	0.037
Rel	reticuloendotheliosis oncogene	0.037
Gpr132	G protein-coupled receptor 132	0.037
AF251705	cDNA sequence AF251705	0.036	Mouse
Gpr35	G protein-coupled receptor 35	0.035
Marco	macrophage receptor with collagenous structure	0.035
Fcgr4	Fc receptor, IgG, low affinity IV	0.034
Pou2f2	POU domain, class 2, transcription factor 2	0.034
Hcls1	hematopoietic cell specific Lyn substrate 1	0.034
Ptpre	protein tyrosine phosphatase, receptor type, E	0.033
Ptpra	protein tyrosine phosphatase, receptor type, A	0.033
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.033
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.033
Cd300lb	CD300 antigen like family member B	0.033	Mouse
Ager	advanced glycosylation end product-specific receptor	0.032
Sirpa	signal-regulatory protein alpha	0.031
Fpr1	formyl peptide receptor 1	0.031
Mb	myoglobin	0.030
Il1b	interleukin 1 beta	0.030
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.030
F7	coagulation factor VII	0.029
Tnf	tumor necrosis factor	0.029
Ncr1	natural cytotoxicity triggering receptor 1	0.029
Cd300ld	CD300 molecule-like family member d	0.028	Mouse
Plaur	plasminogen activator, urokinase receptor	0.027
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.027
Adam8	a disintegrin and metallopeptidase domain 8	0.027
Adamdec1	ADAM-like, decysin 1	0.026
Itk	IL2-inducible T-cell kinase	0.025
Trem1	triggering receptor expressed on myeloid cells 1	0.025
Fcgr3	Fc receptor, IgG, low affinity III	0.025	Mouse
Il18rap	interleukin 18 receptor accessory protein	0.024
Pou2af1	POU domain, class 2, associating factor 1	0.024
Cd300lf	CD300 antigen like family member F	0.024	Mouse
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.024
Ncf1	neutrophil cytosolic factor 1	0.023
Bcar1	breast cancer anti-estrogen resistance 1	0.023
Cr2	complement receptor 2	0.023
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.022
Ccl4	chemokine (C-C motif) ligand 4	0.022
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.022
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.021
Eya4	eyes absent 4 homolog (Drosophila)	0.021
Sh3bp2	SH3-domain binding protein 2	0.021
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.021
Cd80	CD80 antigen	0.021
Rgs14	regulator of G-protein signaling 14	0.020
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.020
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.020
Sfpi1	SFFV proviral integration 1	0.020
Ccl17	chemokine (C-C motif) ligand 17	0.020
Ccl9	chemokine (C-C motif) ligand 9	0.020
Vav1	vav 1 oncogene	0.020
BC013712	cDNA sequence BC013712	0.020
Mmp9	matrix metallopeptidase 9	0.019
C3ar1	complement component 3a receptor 1	0.019
Slc15a3	solute carrier family 15, member 3	0.019
Lyz2	lysozyme 2	0.018
Cd68	CD68 antigen	0.018
Snx20	sorting nexin 20	0.018
Fasl	Fas ligand (TNF superfamily, member 6)	0.018
Cd6	CD6 antigen	0.018
Cd300a	CD300A antigen	0.018
Itgb2	integrin beta 2	0.017
Cd14	CD14 antigen	0.017
Il1f9	interleukin 1 family, member 9	0.017
Bst1	bone marrow stromal cell antigen 1	0.017
Ptafr	platelet-activating factor receptor	0.017
Fyn	Fyn proto-oncogene	0.017	Mouse
Cd8a	CD8 antigen, alpha chain	0.017
Hhex	hematopoietically expressed homeobox	0.017
Clec4e	C-type lectin domain family 4, member e	0.016
Vpreb3	pre-B lymphocyte gene 3	0.016
Trpm2	transient receptor potential cation channel, subfamily M, member 2	0.016
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.016
Clec4a2	C-type lectin domain family 4, member a2	0.016
Cd86	CD86 antigen	0.016
Hmha1	histocompatibility (minor) HA-1	0.016
Gm14548	predicted gene 14548	0.016
Fpr2	formyl peptide receptor 2	0.016
Clnk	cytokine-dependent hematopoietic cell linker	0.015
Cd33	CD33 antigen	0.015
Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18	0.015
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.015
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.015
Cnr2	cannabinoid receptor 2 (macrophage)	0.015
Mcoln2	mucolipin 2	0.015
Cd160	CD160 antigen	0.015
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.015
Cd180	CD180 antigen	0.015
Il6	interleukin 6	0.014
Ly9	lymphocyte antigen 9	0.014
Apobr	apolipoprotein B receptor	0.014
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.014
Gpr182	G protein-coupled receptor 182	0.014
Fosl2	fos-like antigen 2	0.014
C130050O18Rik	RIKEN cDNA C130050O18 gene	0.014
Sell	selectin, lymphocyte	0.014
Mxd1	MAX dimerization protein 1	0.013
Irf5	interferon regulatory factor 5	0.013
Card11	caspase recruitment domain family, member 11	0.013
Cd7	CD7 antigen	0.013
Plekho2	pleckstrin homology domain containing, family O member 2	0.013
Tmem106a	transmembrane protein 106A	0.013
Cd40lg	CD40 ligand	0.013
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.013
Jak2	Janus kinase 2	0.013
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
Il17a	interleukin 17A	0.013
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.013
Gna15	guanine nucleotide binding protein, alpha 15	0.012
Fyb	FYN binding protein	0.012
Mmp19	matrix metallopeptidase 19	0.012
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.012
Il1a	interleukin 1 alpha	0.012
Skap2	src family associated phosphoprotein 2	0.012
Sit1	suppression inducing transmembrane adaptor 1	0.012
Ephb2	Eph receptor B2	0.012
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.012
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.012
Tlr6	toll-like receptor 6	0.012
Igsf6	immunoglobulin superfamily, member 6	0.012
4833422F24Rik	RIKEN cDNA 4833422F24 gene	0.012
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.012
Treml1	triggering receptor expressed on myeloid cells-like 1	0.012
Plek	pleckstrin	0.012
Myo1f	myosin IF	0.012
Sla2	Src-like-adaptor 2	0.011
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.011
F10	coagulation factor X	0.011
Bdnf	brain derived neurotrophic factor	0.011
Zeb1	zinc finger E-box binding homeobox 1	0.011
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.011
Pcdh12	protocadherin 12	0.011
Cxcr3	chemokine (C-X-C motif) receptor 3	0.011
Fcrl1	Fc receptor-like 1	0.011
Itgam	integrin alpha M	0.011
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.010
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.010
Itgax	integrin alpha X	0.010
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.010
Tmprss2	transmembrane protease, serine 2	0.010
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.010
Litaf	LPS-induced TN factor	0.010
Sftpb	surfactant associated protein B	0.010
Frs2	fibroblast growth factor receptor substrate 2	0.010
Tlr8	toll-like receptor 8	0.010
Gp1bb	glycoprotein Ib, beta polypeptide	0.010
Cd5l	CD5 antigen-like	0.010
Cdcp1	CUB domain containing protein 1	0.010