IMP

Process View

Mus musculus

17 genes annotated in mouse

Multi-species View

regulation of macrophage activation

GO:0043030

Any process that modulates the frequency or rate of macrophage activation.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of macrophage activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of macrophage activation" (in gray)

Name	Description	Probability	Func Analog Organism
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.970	Mouse
Il1rl1	interleukin 1 receptor-like 1	0.945
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.913	Mouse
Stat6	signal transducer and activator of transcription 6	0.752
Il1r1	interleukin 1 receptor, type I	0.537	Mouse
Il4ra	interleukin 4 receptor, alpha	0.514
Ghr	growth hormone receptor	0.480
Hspa9	heat shock protein 9	0.363
U46068	cDNA sequence U46068	0.210
Atxn1	ataxin 1	0.186
Il1rap	interleukin 1 receptor accessory protein	0.183	Mouse
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.181
Chi3l3	chitinase 3-like 3	0.167
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.158
F7	coagulation factor VII	0.151
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.142
Mmp8	matrix metallopeptidase 8	0.141
Selp	selectin, platelet	0.128
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.119
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.117
Cxcr2	chemokine (C-X-C motif) receptor 2	0.107
Il33	interleukin 33	0.095
Pigr	polymeric immunoglobulin receptor	0.091
Il18rap	interleukin 18 receptor accessory protein	0.081	Mouse
Il6	interleukin 6	0.077
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.074
Mefv	Mediterranean fever	0.074
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.074
C5ar1	complement component 5a receptor 1	0.072
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.071
Il1rn	interleukin 1 receptor antagonist	0.071
Stat3	signal transducer and activator of transcription 3	0.068
Slpi	secretory leukocyte peptidase inhibitor	0.067
Cd44	CD44 antigen	0.065
Il1b	interleukin 1 beta	0.062
Adam8	a disintegrin and metallopeptidase domain 8	0.059
Sntb1	syntrophin, basic 1	0.055
Soat2	sterol O-acyltransferase 2	0.054
Hp	haptoglobin	0.054
Muc13	mucin 13, epithelial transmembrane	0.049
Osmr	oncostatin M receptor	0.049
Steap4	STEAP family member 4	0.049
Tcap	titin-cap	0.048
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.048
Ccl17	chemokine (C-C motif) ligand 17	0.047
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.046
Sftpd	surfactant associated protein D	0.046
Clec4e	C-type lectin domain family 4, member e	0.046
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.043
Zbtb16	zinc finger and BTB domain containing 16	0.042
Ptf1a	pancreas specific transcription factor, 1a	0.042
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.039
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.038
Il17a	interleukin 17A	0.036
Reg3g	regenerating islet-derived 3 gamma	0.036
Krt4	keratin 4	0.036
Clca1	chloride channel calcium activated 1	0.036
Tff1	trefoil factor 1	0.036	Mouse
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.036
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.035
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.035
Cxcl2	chemokine (C-X-C motif) ligand 2	0.034
Bdkrb1	bradykinin receptor, beta 1	0.033
Hba-a2	hemoglobin alpha, adult chain 2	0.033
Msr1	macrophage scavenger receptor 1	0.032
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.032
Mdm2	transformed mouse 3T3 cell double minute 2	0.032
Cxcl1	chemokine (C-X-C motif) ligand 1	0.031
Plaur	plasminogen activator, urokinase receptor	0.031
Krtap5-1	keratin associated protein 5-1	0.031
Gpr97	G protein-coupled receptor 97	0.031
Slfn4	schlafen 4	0.031
Thrb	thyroid hormone receptor beta	0.031
Trp63	transformation related protein 63	0.030
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.030
Vhl	von Hippel-Lindau tumor suppressor	0.030
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.029
Runx1	runt related transcription factor 1	0.029
Reln	reelin	0.028
Inhba	inhibin beta-A	0.028
Rgs16	regulator of G-protein signaling 16	0.027
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.027
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.027
Gpr132	G protein-coupled receptor 132	0.026
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.025
Krt71	keratin 71	0.025
Tollip	toll interacting protein	0.024
Hivep3	human immunodeficiency virus type I enhancer binding protein 3	0.023
Ifng	interferon gamma	0.023
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.023
Ahr	aryl-hydrocarbon receptor	0.023
Gcgr	glucagon receptor	0.023
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.023
F10	coagulation factor X	0.023
Ins1	insulin I	0.022
C4b	complement component 4B (Childo blood group)	0.022
Masp2	mannan-binding lectin serine peptidase 2	0.022
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.022
C80012	expressed sequence C80012	0.022
Reg1	regenerating islet-derived 1	0.021
Cldn2	claudin 2	0.021
Alox12e	arachidonate lipoxygenase, epidermal	0.021
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.021
Gypa	glycophorin A	0.021
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.021
Ptx3	pentraxin related gene	0.021
Gsdma3	gasdermin A3	0.021
Sele	selectin, endothelial cell	0.020
Vnn3	vanin 3	0.020
Apoa1	apolipoprotein A-I	0.020
Il1r2	interleukin 1 receptor, type II	0.020	Mouse
Hlf	hepatic leukemia factor	0.020
Il13	interleukin 13	0.020
H2-Q10	histocompatibility 2, Q region locus 10	0.020
Gnrh1	gonadotropin releasing hormone 1	0.019
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.019
Itga2	integrin alpha 2	0.019
Foxa3	forkhead box A3	0.019
Fmo3	flavin containing monooxygenase 3	0.019
Chi3l4	chitinase 3-like 4	0.019
Hdc	histidine decarboxylase	0.019
Tmem38b	transmembrane protein 38B	0.019
Clec4d	C-type lectin domain family 4, member d	0.019
Fcgbp	Fc fragment of IgG binding protein	0.019
Alas2	aminolevulinic acid synthase 2, erythroid	0.019
Rel	reticuloendotheliosis oncogene	0.018
Fst	follistatin	0.018
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.018
Ltf	lactotransferrin	0.018
Scgb3a1	secretoglobin, family 3A, member 1	0.018
Gp2	glycoprotein 2 (zymogen granule membrane)	0.018
Sftpa1	surfactant associated protein A1	0.018
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.018
Krt32	keratin 32	0.017
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.017
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.017
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.017
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.017
Per3	period homolog 3 (Drosophila)	0.017
Defa-rs12	defensin, alpha, related sequence 12	0.017
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.017
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.017
Beta-s	hemoglobin subunit beta-1-like	0.017
Igj	immunoglobulin joining chain	0.017
Defa-rs2	defensin, alpha, related sequence 2	0.017
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.017
Hr	hairless	0.017
2310007L24Rik	RIKEN cDNA 2310007L24 gene	0.016
Mat1a	methionine adenosyltransferase I, alpha	0.016
Ptprj	protein tyrosine phosphatase, receptor type, J	0.016
Ahsp	alpha hemoglobin stabilizing protein	0.016
Trem1	triggering receptor expressed on myeloid cells 1	0.016
Lrpprc	leucine-rich PPR-motif containing	0.016
Elk4	ELK4, member of ETS oncogene family	0.016
Hgfac	hepatocyte growth factor activator	0.016
Cd80	CD80 antigen	0.016
Sycn	syncollin	0.016
Ccr4	chemokine (C-C motif) receptor 4	0.015
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.015
Cxcl5	chemokine (C-X-C motif) ligand 5	0.015
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.015
Hamp2	hepcidin antimicrobial peptide 2	0.015
Chi3l1	chitinase 3-like 1	0.015
Il9r	interleukin 9 receptor	0.015
S1pr4	sphingosine-1-phosphate receptor 4	0.015
Gpr182	G protein-coupled receptor 182	0.015
Mmp19	matrix metallopeptidase 19	0.015
Ltb4r1	leukotriene B4 receptor 1	0.015
Timm8a1	translocase of inner mitochondrial membrane 8 homolog a1 (yeast)	0.015
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.014
Pcx	pyruvate carboxylase	0.014
Lgals2	lectin, galactose-binding, soluble 2	0.014
Hbb-b2	hemoglobin, beta adult minor chain	0.014
Acp2	acid phosphatase 2, lysosomal	0.014
Wnt9b	wingless-type MMTV integration site 9B	0.014
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.014
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.014
Mmp7	matrix metallopeptidase 7	0.013
Aff1	AF4/FMR2 family, member 1	0.013
Nfe2	nuclear factor, erythroid derived 2	0.013
Hnf1b	HNF1 homeobox B	0.013
Elf3	E74-like factor 3	0.013
Tgfbr3	transforming growth factor, beta receptor III	0.013
Cd177	CD177 antigen	0.013
Cd300lf	CD300 antigen like family member F	0.013
Tgfa	transforming growth factor alpha	0.013
Dnm2	dynamin 2	0.013
Lrrk2	leucine-rich repeat kinase 2	0.013
Fpr1	formyl peptide receptor 1	0.013
Thbs2	thrombospondin 2	0.013
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.013
Ctse	cathepsin E	0.013
Ocel1	occludin/ELL domain containing 1	0.012
Avp	arginine vasopressin	0.012
Kit	kit oncogene	0.012
Gip	gastric inhibitory polypeptide	0.012
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.012
Pvr	poliovirus receptor	0.012
Fzd4	frizzled homolog 4 (Drosophila)	0.012
Lce3c	late cornified envelope 3C	0.012
Cpa3	carboxypeptidase A3, mast cell	0.012
Fshr	follicle stimulating hormone receptor	0.012
Sult5a1	sulfotransferase family 5A, member 1	0.012
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
Npc1	Niemann Pick type C1	0.012
Pglyrp1	peptidoglycan recognition protein 1	0.012
Egfr	epidermal growth factor receptor	0.012
Ehf	ets homologous factor	0.012
Slc7a15	solute carrier family 7 (cationic amino acid transporter, y+ system), member 15	0.012
Fas	Fas (TNF receptor superfamily member 6)	0.012
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
Cnga1	cyclic nucleotide gated channel alpha 1	0.012
Nlrp3	NLR family, pyrin domain containing 3	0.011
Dnahc2	dynein, axonemal, heavy chain 2	0.011
Ptges	prostaglandin E synthase	0.011
Lif	leukemia inhibitory factor	0.011
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.011
Ins2	insulin II	0.011
Mmp3	matrix metallopeptidase 3	0.011
Foxn4	forkhead box N4	0.011
Cd207	CD207 antigen	0.011
Inpp5k	inositol polyphosphate 5-phosphatase K	0.011
Krt6a	keratin 6A	0.011
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.011
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.011
Tspo2	translocator protein 2	0.011
Ngp	neutrophilic granule protein	0.011
Cish	cytokine inducible SH2-containing protein	0.011
Il13ra1	interleukin 13 receptor, alpha 1	0.011
Il2	interleukin 2	0.011
2010002N04Rik	RIKEN cDNA 2010002N04 gene	0.011
Spink4	serine peptidase inhibitor, Kazal type 4	0.010
Adamdec1	ADAM-like, decysin 1	0.010
Dock5	dedicator of cytokinesis 5	0.010
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.010
Litaf	LPS-induced TN factor	0.010
Plek	pleckstrin	0.010
Azgp1	alpha-2-glycoprotein 1, zinc	0.010
Tmem176a	transmembrane protein 176A	0.010
Cel	carboxyl ester lipase	0.010
Asprv1	aspartic peptidase, retroviral-like 1	0.010
Sdcbp2	syndecan binding protein (syntenin) 2	0.010
Il21r	interleukin 21 receptor	0.010
Ccrl2	chemokine (C-C motif) receptor-like 2	0.010
Errfi1	ERBB receptor feedback inhibitor 1	0.010