IMP

Process View

Mus musculus

17 genes annotated in mouse

regulation of triglyceride metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of triglyceride metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of triglyceride metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Lep	leptin	1.000
Pnpla2	patatin-like phospholipase domain containing 2	0.999
Apoe	apolipoprotein E	0.998
Ghr	growth hormone receptor	0.998
Abhd5	abhydrolase domain containing 5	0.997
Lepr	leptin receptor	0.997
Pparg	peroxisome proliferator activated receptor gamma	0.993
Cav1	caveolin 1, caveolae protein	0.933
Thra	thyroid hormone receptor alpha	0.932
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.930
Cidec	cell death-inducing DFFA-like effector c	0.882
Lpin1	lipin 1	0.859
Nos3	nitric oxide synthase 3, endothelial cell	0.854
Ar	androgen receptor	0.849
Esr1	estrogen receptor 1 (alpha)	0.799	Rat
Dab1	disabled homolog 1 (Drosophila)	0.727
Prlr	prolactin receptor	0.626
Lef1	lymphoid enhancer binding factor 1	0.626	Mouse
Irs2	insulin receptor substrate 2	0.550
Ren1	renin 1 structural	0.457
Adipoq	adiponectin, C1Q and collagen domain containing	0.415
Ncor1	nuclear receptor co-repressor 1	0.406
Pten	phosphatase and tensin homolog	0.400
Insr	insulin receptor	0.381
Adrb3	adrenergic receptor, beta 3	0.352
Kiss1	KiSS-1 metastasis-suppressor	0.348
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.340
Scd1	stearoyl-Coenzyme A desaturase 1	0.307
Tcf7	transcription factor 7, T-cell specific	0.268	Mouse
Lipe	lipase, hormone sensitive	0.240
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.238	Mouse
Nos1	nitric oxide synthase 1, neuronal	0.236
Npc1	Niemann Pick type C1	0.231
Plin5	perilipin 5	0.222
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.203
Drd2	dopamine receptor D2	0.187
Agtr1a	angiotensin II receptor, type 1a	0.180
Lcat	lecithin cholesterol acyltransferase	0.179
Ccna2	cyclin A2	0.175
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.160
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.150	Mouse
Kit	kit oncogene	0.141
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.126	Mouse
Vdr	vitamin D receptor	0.124
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.113
Retn	resistin	0.108
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.105	Mouse
Rxra	retinoid X receptor alpha	0.086
Lss	lanosterol synthase	0.086
Flt1	FMS-like tyrosine kinase 1	0.082
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.081
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.080
Stat5a	signal transducer and activator of transcription 5A	0.079
Il1r1	interleukin 1 receptor, type I	0.079
Hp	haptoglobin	0.079
Ccne1	cyclin E1	0.078
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.074
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.070
Fga	fibrinogen alpha chain	0.069
Reln	reelin	0.065
Alb	albumin	0.062
Fabp4	fatty acid binding protein 4, adipocyte	0.061
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.060
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.060
Bcl2	B-cell leukemia/lymphoma 2	0.059
Srf	serum response factor	0.057
Sqle	squalene epoxidase	0.056
Gnrh1	gonadotropin releasing hormone 1	0.055
Fshr	follicle stimulating hormone receptor	0.055
Bglap	bone gamma carboxyglutamate protein	0.054
Adipor2	adiponectin receptor 2	0.052
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.051
Amhr2	anti-Mullerian hormone type 2 receptor	0.051
Ctnnb1	catenin (cadherin associated protein), beta 1	0.051
Plin4	perilipin 4	0.050
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.047
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.047
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.046	Mouse
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.046
Mrap	melanocortin 2 receptor accessory protein	0.045
Irs1	insulin receptor substrate 1	0.045
Ccnb2	cyclin B2	0.045
Plin1	perilipin 1	0.045	Fly
Cfd	complement factor D (adipsin)	0.044
H1	histocompatibility 1	0.044
Npy1r	neuropeptide Y receptor Y1	0.043
Tgfb1	transforming growth factor, beta 1	0.043
Fasn	fatty acid synthase	0.041
Lpl	lipoprotein lipase	0.041
Slc12a6	solute carrier family 12, member 6	0.040
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.040	Mouse
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.039	Human
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.037
C4b	complement component 4B (Childo blood group)	0.037
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.036
Apoc1	apolipoprotein C-I	0.036
Rb1	retinoblastoma 1	0.036
Ahsg	alpha-2-HS-glycoprotein	0.036
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.035
Tlr2	toll-like receptor 2	0.035
Notch2	Notch gene homolog 2 (Drosophila)	0.035
Dhcr7	7-dehydrocholesterol reductase	0.035
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.035
Stat3	signal transducer and activator of transcription 3	0.035
Pcx	pyruvate carboxylase	0.034
Adig	adipogenin	0.034
Wasf2	WAS protein family, member 2	0.034
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.033
Kiss1r	KISS1 receptor	0.033
Lrp1	low density lipoprotein receptor-related protein 1	0.033
Ncoa1	nuclear receptor coactivator 1	0.033
Apoa1	apolipoprotein A-I	0.033
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.032
Cyp51	cytochrome P450, family 51	0.032
Cp	ceruloplasmin	0.031
Vldlr	very low density lipoprotein receptor	0.031	Mouse
Nos2	nitric oxide synthase 2, inducible	0.030
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.030
Mpv17	MpV17 mitochondrial inner membrane protein	0.030
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.029
Car3	carbonic anhydrase 3	0.029
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.029
Ccl2	chemokine (C-C motif) ligand 2	0.028
Igf1	insulin-like growth factor 1	0.028
Crp	C-reactive protein, pentraxin-related	0.028
Psen1	presenilin 1	0.028
Apof	apolipoprotein F	0.027
Ncoa3	nuclear receptor coactivator 3	0.027
Nnmt	nicotinamide N-methyltransferase	0.026
Stat5b	signal transducer and activator of transcription 5B	0.025
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.025
Gjb2	gap junction protein, beta 2	0.025
Vav2	vav 2 oncogene	0.025
LOC100503041	PDZ domain-containing protein 7-like	0.024
Hamp	hepcidin antimicrobial peptide	0.024
Mstn	myostatin	0.024
Fas	Fas (TNF receptor superfamily member 6)	0.024
Timp4	tissue inhibitor of metalloproteinase 4	0.024
Ahr	aryl-hydrocarbon receptor	0.024
Fgg	fibrinogen gamma chain	0.023
Rxrg	retinoid X receptor gamma	0.023
Scd2	stearoyl-Coenzyme A desaturase 2	0.023
Ccnb1	cyclin B1	0.023
Sc4mol	sterol-C4-methyl oxidase-like	0.023
Egfr	epidermal growth factor receptor	0.023
Trp53	transformation related protein 53	0.023
Orm1	orosomucoid 1	0.023
Adrb1	adrenergic receptor, beta 1	0.022
Lrp5	low density lipoprotein receptor-related protein 5	0.022
Ccnd1	cyclin D1	0.022
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.021
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.021
Ptch1	patched homolog 1	0.021
Esr2	estrogen receptor 2 (beta)	0.021
C9	complement component 9	0.020
Agtr2	angiotensin II receptor, type 2	0.020
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.020
F2	coagulation factor II	0.019
Steap4	STEAP family member 4	0.019
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.019	Mouse
Apc	adenomatosis polyposis coli	0.019
Cxcl10	chemokine (C-X-C motif) ligand 10	0.018
Vgf	VGF nerve growth factor inducible	0.018
Clock	circadian locomotor output cycles kaput	0.018
Nf1	neurofibromatosis 1	0.018
Vnn3	vanin 3	0.017
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.017
Acly	ATP citrate lyase	0.017
Angptl4	angiopoietin-like 4	0.017
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.017
Akr1c6	aldo-keto reductase family 1, member C6	0.017
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.017
Vegfa	vascular endothelial growth factor A	0.017
Cox8b	cytochrome c oxidase, subunit VIIIb	0.017
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.016
Plin2	perilipin 2	0.016
Ces1c	carboxylesterase 1C	0.016
Tbc1d4	TBC1 domain family, member 4	0.016
Mup4	major urinary protein 4	0.016
Mup3	major urinary protein 3	0.016
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.016
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.016
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.016	Mouse
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.016
Gpr182	G protein-coupled receptor 182	0.015
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.015
Tshr	thyroid stimulating hormone receptor	0.015
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.015
Rpgrip1l	Rpgrip1-like	0.015
Ldlr	low density lipoprotein receptor	0.015
Prss1	protease, serine, 1 (trypsin 1)	0.015
Mapk8	mitogen-activated protein kinase 8	0.015
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.015
Dhcr24	24-dehydrocholesterol reductase	0.015
Fads2	fatty acid desaturase 2	0.014
Cd5l	CD5 antigen-like	0.014
Pzp	pregnancy zone protein	0.014
Kl	klotho	0.014
Ugt3a2	UDP glycosyltransferases 3 family, polypeptide A2	0.014
Wwox	WW domain-containing oxidoreductase	0.014
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.014
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.014
Tmprss11e	transmembrane protease, serine 11e	0.014
Ambp	alpha 1 microglobulin/bikunin	0.014
Duox2	dual oxidase 2	0.014
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.014
Art3	ADP-ribosyltransferase 3	0.013
Gys2	glycogen synthase 2	0.013
F13b	coagulation factor XIII, beta subunit	0.013
Adrb2	adrenergic receptor, beta 2	0.013
Hist1h1a	histone cluster 1, H1a	0.013
Pou3f1	POU domain, class 3, transcription factor 1	0.013
Fgf21	fibroblast growth factor 21	0.013
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.013
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.013
Hnf4a	hepatic nuclear factor 4, alpha	0.012
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.012
Tbx3	T-box 3	0.012
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.012
Dio1	deiodinase, iodothyronine, type I	0.012
Lmf1	lipase maturation factor 1	0.012
Kng1	kininogen 1	0.012
Plg	plasminogen	0.012
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.012
Ces1d	carboxylesterase 1D	0.012
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.012
Cd36	CD36 antigen	0.012	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.012
Dmgdh	dimethylglycine dehydrogenase precursor	0.012
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.012
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.011
Adra1b	adrenergic receptor, alpha 1b	0.011
Fgb	fibrinogen beta chain	0.011
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.011
Tbpl2	TATA box binding protein like 2	0.011
Pah	phenylalanine hydroxylase	0.011
Cdca8	cell division cycle associated 8	0.011
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.011
Ppara	peroxisome proliferator activated receptor alpha	0.011
Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	0.011
Ptgs2	prostaglandin-endoperoxide synthase 2	0.011
Mt1	metallothionein 1	0.011
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.010
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.010
Fmo1	flavin containing monooxygenase 1	0.010
Inmt	indolethylamine N-methyltransferase	0.010
H2-Q10	histocompatibility 2, Q region locus 10	0.010
Fgf1	fibroblast growth factor 1	0.010
Gsta3	glutathione S-transferase, alpha 3	0.010
Angptl3	angiopoietin-like 3	0.010
Idi1	isopentenyl-diphosphate delta isomerase	0.010
Rdh7	retinol dehydrogenase 7	0.010
Vhl	von Hippel-Lindau tumor suppressor	0.010