IMP

Process View

Mus musculus

3 genes annotated in mouse

embryonic nail plate morphogenesis

The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "embryonic nail plate morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "embryonic nail plate morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Prrx1	paired related homeobox 1	1.000
Fgfr2	fibroblast growth factor receptor 2	0.996
Bmp7	bone morphogenetic protein 7	0.992
Smo	smoothened homolog (Drosophila)	0.985
Dlx5	distal-less homeobox 5	0.968
Eya1	eyes absent 1 homolog (Drosophila)	0.967
Prrx2	paired related homeobox 2	0.966
Gli2	GLI-Kruppel family member GLI2	0.946
Foxc1	forkhead box C1	0.942
Bmp4	bone morphogenetic protein 4	0.941
Tgfb2	transforming growth factor, beta 2	0.932
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.926
Shh	sonic hedgehog	0.919
Hoxa2	homeobox A2	0.917
Msx2	homeobox, msh-like 2	0.907
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.808
Msx1	homeobox, msh-like 1	0.793
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.773
Runx2	runt related transcription factor 2	0.761
Pbx1	pre B-cell leukemia transcription factor 1	0.724
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.719
Sox9	SRY-box containing gene 9	0.684
Ednra	endothelin receptor type A	0.671
Alx4	aristaless-like homeobox 4	0.649
Fgfr1	fibroblast growth factor receptor 1	0.600
Fzd1	frizzled homolog 1 (Drosophila)	0.578	Mouse
Wnt5a	wingless-related MMTV integration site 5A	0.541
Tcfap2a	transcription factor AP-2, alpha	0.539
Gpc3	glypican 3	0.531
Ptk7	PTK7 protein tyrosine kinase 7	0.482
Gas1	growth arrest specific 1	0.455
Gopc	golgi associated PDZ and coiled-coil motif containing	0.452
Foxc2	forkhead box C2	0.368
Smad6	MAD homolog 6 (Drosophila)	0.365
Pax9	paired box gene 9	0.359
Tbx15	T-box 15	0.330
Gsc	goosecoid homeobox	0.319
Efna2	ephrin A2	0.317
Tbx1	T-box 1	0.307
Dlx2	distal-less homeobox 2	0.283
Hoxb6	homeobox B6	0.280
Hand1	heart and neural crest derivatives expressed transcript 1	0.265
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.257
Fgf8	fibroblast growth factor 8	0.222
Pax3	paired box gene 3	0.219
Lef1	lymphoid enhancer binding factor 1	0.213
Acvr1	activin A receptor, type 1	0.199
Hes1	hairy and enhancer of split 1 (Drosophila)	0.189
Fgfr3	fibroblast growth factor receptor 3	0.186
Zfp185	zinc finger protein 185	0.182
Twist2	twist homolog 2 (Drosophila)	0.182
Efnb1	ephrin B1	0.178
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.173
Alx1	ALX homeobox 1	0.172
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.166
Tead2	TEA domain family member 2	0.165
Rarg	retinoic acid receptor, gamma	0.159
Efs	embryonal Fyn-associated substrate	0.151
Chrd	chordin	0.148
Vangl2	vang-like 2 (van gogh, Drosophila)	0.145
Fzd2	frizzled homolog 2 (Drosophila)	0.144	Mouse
Fbln1	fibulin 1	0.144
Ptch1	patched homolog 1	0.142
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.136
Fgf10	fibroblast growth factor 10	0.127
Grb10	growth factor receptor bound protein 10	0.127
Foxg1	forkhead box G1	0.120
Tbx3	T-box 3	0.115
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.115
Pitx2	paired-like homeodomain transcription factor 2	0.115
Fzd7	frizzled homolog 7 (Drosophila)	0.113	Mouse
Hoxd9	homeobox D9	0.111
En1	engrailed 1	0.109
Ephb3	Eph receptor B3	0.108
Otx2	orthodenticle homolog 2 (Drosophila)	0.107
Sox2	SRY-box containing gene 2	0.107
Bmp2	bone morphogenetic protein 2	0.105
Mrc2	mannose receptor, C type 2	0.104
Cachd1	cache domain containing 1	0.102
Emp2	epithelial membrane protein 2	0.102
Sfrp1	secreted frizzled-related protein 1	0.099
Col4a5	collagen, type IV, alpha 5	0.097
Hoxb3	homeobox B3	0.095
Twist1	twist homolog 1 (Drosophila)	0.095
Gli1	GLI-Kruppel family member GLI1	0.095
Hoxa9	homeobox A9	0.094
Hand2	heart and neural crest derivatives expressed transcript 2	0.089
Sfrp2	secreted frizzled-related protein 2	0.084
Zeb1	zinc finger E-box binding homeobox 1	0.081
Capn6	calpain 6	0.080
Mn1	meningioma 1	0.080
Sstr4	somatostatin receptor 4	0.079
Foxd1	forkhead box D1	0.078
Vegfa	vascular endothelial growth factor A	0.076
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.073
Dlg4	discs, large homolog 4 (Drosophila)	0.072
Efna4	ephrin A4	0.072
Smad3	MAD homolog 3 (Drosophila)	0.071
Tbx2	T-box 2	0.071
Fzd8	frizzled homolog 8 (Drosophila)	0.068	Mouse
Zfp503	zinc finger protein 503	0.068
Hoxa3	homeobox A3	0.068
Zfhx4	zinc finger homeodomain 4	0.066
En2	engrailed 2	0.064
Pitx1	paired-like homeodomain transcription factor 1	0.062
Tpbg	trophoblast glycoprotein	0.060
Mfap2	microfibrillar-associated protein 2	0.058
Jag1	jagged 1	0.058
Npr3	natriuretic peptide receptor 3	0.057
Creb3l1	cAMP responsive element binding protein 3-like 1	0.057
Fzd6	frizzled homolog 6 (Drosophila)	0.057
Cul7	cullin 7	0.057
Lrp6	low density lipoprotein receptor-related protein 6	0.055
Hoxa1	homeobox A1	0.054
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.052
Wnt1	wingless-related MMTV integration site 1	0.052
Tshz1	teashirt zinc finger family member 1	0.051
Disp1	dispatched homolog 1 (Drosophila)	0.051
Bmp5	bone morphogenetic protein 5	0.049
Hoxd10	homeobox D10	0.047
Tcfap2c	transcription factor AP-2, gamma	0.047
Ephb2	Eph receptor B2	0.046
Fjx1	four jointed box 1 (Drosophila)	0.046
Hoxa11	homeobox A11	0.043
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.042
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.041
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.040
Trp63	transformation related protein 63	0.040
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.040
Alx3	aristaless-like homeobox 3	0.040
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.038
Meis2	Meis homeobox 2	0.038
Ptch2	patched homolog 2	0.037
Hoxc4	homeobox C4	0.037
Pax6	paired box gene 6	0.037
Lrp2	low density lipoprotein receptor-related protein 2	0.036
Cdh6	cadherin 6	0.036
Thbs3	thrombospondin 3	0.036
Wnt7b	wingless-related MMTV integration site 7B	0.036
Wnt5b	wingless-related MMTV integration site 5B	0.035
Wwtr1	WW domain containing transcription regulator 1	0.035
Stra6	stimulated by retinoic acid gene 6	0.035
Tgfbr3	transforming growth factor, beta receptor III	0.035
Wnt6	wingless-related MMTV integration site 6	0.035
Rarb	retinoic acid receptor, beta	0.034
S1pr3	sphingosine-1-phosphate receptor 3	0.034
Axin2	axin2	0.034
Uts2r	urotensin 2 receptor	0.033
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.033
Wnt3a	wingless-related MMTV integration site 3A	0.033
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.033
Col9a1	collagen, type IX, alpha 1	0.033
Hoxd8	homeobox D8	0.033
Notch3	Notch gene homolog 3 (Drosophila)	0.033
Hoxd4	homeobox D4	0.032
Tcf15	transcription factor 15	0.032
Cdh3	cadherin 3	0.032
Aplnr	apelin receptor	0.032
Efnb2	ephrin B2	0.032
Krtap5-1	keratin associated protein 5-1	0.031
Neo1	neogenin	0.031
Dlk1	delta-like 1 homolog (Drosophila)	0.031
Itga8	integrin alpha 8	0.031
Sh3rf1	SH3 domain containing ring finger 1	0.030
Hoxc8	homeobox C8	0.030
Hoxb4	homeobox B4	0.030
Sox13	SRY-box containing gene 13	0.030
Hoxb5	homeobox B5	0.030
Hoxa10	homeobox A10	0.029
Id4	inhibitor of DNA binding 4	0.029
Hrc	histidine rich calcium binding protein	0.029
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.029
Irs1	insulin receptor substrate 1	0.029
Has2	hyaluronan synthase 2	0.028
Dlg1	discs, large homolog 1 (Drosophila)	0.028
Gdf10	growth differentiation factor 10	0.028
Ddr2	discoidin domain receptor family, member 2	0.028
Smtn	smoothelin	0.027
Ctnnal1	catenin (cadherin associated protein), alpha-like 1	0.027
Gjb5	gap junction protein, beta 5	0.027
Bnc1	basonuclin 1	0.027
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.027
Ctnnb1	catenin (cadherin associated protein), beta 1	0.026
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.026
Mmp11	matrix metallopeptidase 11	0.026
Ltbp3	latent transforming growth factor beta binding protein 3	0.026
Gata6	GATA binding protein 6	0.026
Gjc1	gap junction protein, gamma 1	0.026
Igfbp2	insulin-like growth factor binding protein 2	0.025
Hoxd3	homeobox D3	0.025
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.025
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.025
Smad5	MAD homolog 5 (Drosophila)	0.024
Ptprg	protein tyrosine phosphatase, receptor type, G	0.024
Tagln	transgelin	0.024
Smoc2	SPARC related modular calcium binding 2	0.023
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.023
Acvr2b	activin receptor IIB	0.023
Plxna3	plexin A3	0.023
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.023
Zfhx3	zinc finger homeobox 3	0.022
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.022
Col11a1	collagen, type XI, alpha 1	0.022
Ctf1	cardiotrophin 1	0.022
Prx	periaxin	0.022
Tspan9	tetraspanin 9	0.022
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.022
Eda	ectodysplasin-A	0.021
Plcd1	phospholipase C, delta 1	0.021
Cdsn	corneodesmosin	0.021
Irx3	Iroquois related homeobox 3 (Drosophila)	0.021
Tgif2	TGFB-induced factor homeobox 2	0.021
Dll1	delta-like 1 (Drosophila)	0.021
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.021
Rara	retinoic acid receptor, alpha	0.020
Hic1	hypermethylated in cancer 1	0.020
Dlx3	distal-less homeobox 3	0.020
Sox4	SRY-box containing gene 4	0.020
Hoxc5	homeobox C5	0.019
Matn4	matrilin 4	0.019
Lama5	laminin, alpha 5	0.019
Ebf3	early B-cell factor 3	0.019
Sult5a1	sulfotransferase family 5A, member 1	0.019
Tcf21	transcription factor 21	0.019
Nog	noggin	0.019
Pax2	paired box gene 2	0.019
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.019
Peg10	paternally expressed 10	0.019
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.018
Wnt11	wingless-related MMTV integration site 11	0.018
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.018
Dlx6	distal-less homeobox 6	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.018	Mouse
Pax7	paired box gene 7	0.018
Foxd2	forkhead box D2	0.018
Hoxa5	homeobox A5	0.017
Wfdc2	WAP four-disulfide core domain 2	0.017
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.017
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.017
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.017
Nxn	nucleoredoxin	0.017
Lrp5	low density lipoprotein receptor-related protein 5	0.017
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.017
Col2a1	collagen, type II, alpha 1	0.017
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.016
Tyr	tyrosinase	0.016
Parva	parvin, alpha	0.016
Mia1	melanoma inhibitory activity 1	0.016
Fgf18	fibroblast growth factor 18	0.016
Zbtb12	zinc finger and BTB domain containing 12	0.016
Amotl2	angiomotin-like 2	0.016
Epha4	Eph receptor A4	0.016
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.016
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.016
Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	0.016
Galr2	galanin receptor 2	0.016
Etl4	enhancer trap locus 4	0.015
Myog	myogenin	0.015
Btbd3	BTB (POZ) domain containing 3	0.015
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.015
Gm13290	predicted gene 13290	0.015
Per3	period homolog 3 (Drosophila)	0.015
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.015
Epb4.1l4a	erythrocyte protein band 4.1-like 4a	0.015
Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.015
Plagl1	pleiomorphic adenoma gene-like 1	0.015
Col12a1	collagen, type XII, alpha 1	0.015
Dlg2	discs, large homolog 2 (Drosophila)	0.014
Sct	secretin	0.014
Fbn2	fibrillin 2	0.014
Ntf3	neurotrophin 3	0.014
Zfp532	zinc finger protein 532	0.014
Krt5	keratin 5	0.014
Nynrin	NYN domain and retroviral integrase containing	0.014
Lefty1	left right determination factor 1	0.014
Nfia	nuclear factor I/A	0.014
Ednrb	endothelin receptor type B	0.013
Ptprk	protein tyrosine phosphatase, receptor type, K	0.013
Krt33b	keratin 33B	0.013
Mdk	midkine	0.013
Angpt1	angiopoietin 1	0.013
Ptrf	polymerase I and transcript release factor	0.013
Ptpru	protein tyrosine phosphatase, receptor type, U	0.013
S1pr2	sphingosine-1-phosphate receptor 2	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Foxf2	forkhead box F2	0.013
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.013
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.013
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.013
Efna3	ephrin A3	0.013
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.013
Krtap16-4	keratin associated protein 16-4	0.013
Krtap13	keratin associated protein 13	0.013
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.013
Cpa3	carboxypeptidase A3, mast cell	0.013
Hoxb9	homeobox B9	0.013
Pcdh18	protocadherin 18	0.012
Cst9	cystatin 9	0.012
Emx2	empty spiracles homolog 2 (Drosophila)	0.012
Aif1l	allograft inflammatory factor 1-like	0.012
Psapl1	prosaposin-like 1	0.012
Tlx2	T-cell leukemia, homeobox 2	0.012
Sardh	sarcosine dehydrogenase	0.012
Ltbp4	latent transforming growth factor beta binding protein 4	0.012
Ager	advanced glycosylation end product-specific receptor	0.012
Pthlh	parathyroid hormone-like peptide	0.012
Socs5	suppressor of cytokine signaling 5	0.012
Mc5r	melanocortin 5 receptor	0.012
Ntn1	netrin 1	0.012
Cpxm1	carboxypeptidase X 1 (M14 family)	0.012
Ephb4	Eph receptor B4	0.012
Podxl	podocalyxin-like	0.012
Sh3d19	SH3 domain protein D19	0.012
Timp2	tissue inhibitor of metalloproteinase 2	0.012
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.012
Spry4	sprouty homolog 4 (Drosophila)	0.012
Ptgfr	prostaglandin F receptor	0.012
Itgb5	integrin beta 5	0.012
Dpysl2	dihydropyrimidinase-like 2	0.012
Ppl	periplakin	0.012
Apln	apelin	0.012
Prss12	protease, serine, 12 neurotrypsin (motopsin)	0.012
Plxna1	plexin A1	0.012
Calm4	calmodulin 4	0.012
Olfr140	olfactory receptor 140	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Dsg4	desmoglein 4	0.011
Mgat3	mannoside acetylglucosaminyltransferase 3	0.011
Efna1	ephrin A1	0.011
Gata3	GATA binding protein 3	0.011
Cldn8	claudin 8	0.011
Fgd1	FYVE, RhoGEF and PH domain containing 1	0.011
Mmp16	matrix metallopeptidase 16	0.011
Dlx1	distal-less homeobox 1	0.011
Bfsp1	beaded filament structural protein 1, in lens-CP94	0.011
Nrk	Nik related kinase	0.011
Cldn6	claudin 6	0.011
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.011
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.011
Scx	scleraxis	0.011
Ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.011
Sox7	SRY-box containing gene 7	0.011
Wnt4	wingless-related MMTV integration site 4	0.011
Foxd3	forkhead box D3	0.011
Lpar1	lysophosphatidic acid receptor 1	0.011
Gata2	GATA binding protein 2	0.011
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Myl9	myosin, light polypeptide 9, regulatory	0.011
Itga3	integrin alpha 3	0.011
Gbx2	gastrulation brain homeobox 2	0.011
Cxadr	coxsackie virus and adenovirus receptor	0.011
Ptgfrn	prostaglandin F2 receptor negative regulator	0.011
Gjb4	gap junction protein, beta 4	0.011
Mecom	MDS1 and EVI1 complex locus	0.011
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.011
Snai2	snail homolog 2 (Drosophila)	0.011
Fgf15	fibroblast growth factor 15	0.010
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.010
Ptprf	protein tyrosine phosphatase, receptor type, F	0.010
Otx1	orthodenticle homolog 1 (Drosophila)	0.010
Jub	ajuba	0.010
Gpr37	G protein-coupled receptor 37	0.010
Nf1	neurofibromatosis 1	0.010
Fam109a	family with sequence similarity 109, member A	0.010
Ocln	occludin	0.010
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.010
Homer3	homer homolog 3 (Drosophila)	0.010
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.010
Igfbp5	insulin-like growth factor binding protein 5	0.010
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.010
Fam164c	family with sequence similarity 164, member C	0.010
Epha2	Eph receptor A2	0.010
Fgf7	fibroblast growth factor 7	0.010
Foxo4	forkhead box O4	0.010
Mfap4	microfibrillar-associated protein 4	0.010
Foxj1	forkhead box J1	0.010
Hr	hairless	0.010
Pcdh12	protocadherin 12	0.010