IMP

Process View

Mus musculus

18 genes annotated in mouse

trachea development

The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "trachea development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "trachea development" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.998
Fgfr2	fibroblast growth factor receptor 2	0.997	Fly
Sox9	SRY-box containing gene 9	0.996
Ctnnb1	catenin (cadherin associated protein), beta 1	0.989
Apc	adenomatosis polyposis coli	0.981
Nodal	nodal	0.973
Bmp4	bone morphogenetic protein 4	0.971
Rarg	retinoic acid receptor, gamma	0.913
Hoxa2	homeobox A2	0.889
Pax8	paired box gene 8	0.885
Gli3	GLI-Kruppel family member GLI3	0.856
Msx1	homeobox, msh-like 1	0.814
Bmp7	bone morphogenetic protein 7	0.786
Fgf8	fibroblast growth factor 8	0.763
Hoxb3	homeobox B3	0.729
Gli2	GLI-Kruppel family member GLI2	0.721
Fgfr1	fibroblast growth factor receptor 1	0.717	Fly
Hoxb6	homeobox B6	0.695	Mouse
Pbx1	pre B-cell leukemia transcription factor 1	0.693
Hoxa3	homeobox A3	0.689
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.669
Hand1	heart and neural crest derivatives expressed transcript 1	0.664
Prrx1	paired related homeobox 1	0.648
Tgfb2	transforming growth factor, beta 2	0.622
Prrx2	paired related homeobox 2	0.603
Wnt4	wingless-related MMTV integration site 4	0.603	Mouse
Cav1	caveolin 1, caveolae protein	0.602
Hoxa5	homeobox A5	0.593
Hoxb5	homeobox B5	0.589	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.563
Nf1	neurofibromatosis 1	0.530
Tbx1	T-box 1	0.499
Rarb	retinoic acid receptor, beta	0.495	Mouse
Hoxd13	homeobox D13	0.473
Tcfap2a	transcription factor AP-2, alpha	0.466
Smo	smoothened homolog (Drosophila)	0.422
Meox2	mesenchyme homeobox 2	0.418
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.378
Hoxd3	homeobox D3	0.369
Hoxc8	homeobox C8	0.358	Mouse
Epas1	endothelial PAS domain protein 1	0.357	Fly
Pax2	paired box gene 2	0.337
Edar	ectodysplasin-A receptor	0.311
Pax3	paired box gene 3	0.299
Zeb1	zinc finger E-box binding homeobox 1	0.296
Wnt6	wingless-related MMTV integration site 6	0.264	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.255
Hoxa10	homeobox A10	0.235
Hoxa4	homeobox A4	0.232	Mouse
Foxc1	forkhead box C1	0.228
Bmp2	bone morphogenetic protein 2	0.225	Mouse
Hoxd9	homeobox D9	0.224
Hoxa9	homeobox A9	0.216
Lhx1	LIM homeobox protein 1	0.204
Twist2	twist homolog 2 (Drosophila)	0.199
Fgfr3	fibroblast growth factor receptor 3	0.193	Fly
Hoxb2	homeobox B2	0.188
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.186
Chrd	chordin	0.182
Hoxc5	homeobox C5	0.177	Mouse
Rara	retinoic acid receptor, alpha	0.174
Hand2	heart and neural crest derivatives expressed transcript 2	0.168
Smad6	MAD homolog 6 (Drosophila)	0.167
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.164
Gsk3b	glycogen synthase kinase 3 beta	0.161
Wnt3a	wingless-related MMTV integration site 3A	0.156	Mouse
Fgf10	fibroblast growth factor 10	0.154
Tcf21	transcription factor 21	0.153
Sox17	SRY-box containing gene 17	0.149	Mouse
Acvr1	activin A receptor, type 1	0.148	Mouse
Hoxc4	homeobox C4	0.146	Mouse
Ednra	endothelin receptor type A	0.146
Nos3	nitric oxide synthase 3, endothelial cell	0.146
Hoxd4	homeobox D4	0.142	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.136
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.132
Hoxb4	homeobox B4	0.127	Mouse
Kl	klotho	0.123
Sox7	SRY-box containing gene 7	0.119	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.117
Axin1	axin 1	0.115
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.114	Fly
Tbx2	T-box 2	0.110
Foxd2	forkhead box D2	0.109
Wnt11	wingless-related MMTV integration site 11	0.109	Mouse
Zfp503	zinc finger protein 503	0.106
Alx4	aristaless-like homeobox 4	0.106
Ctnna1	catenin (cadherin associated protein), alpha 1	0.106
Dlx5	distal-less homeobox 5	0.105
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.102
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.101
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.099	Mouse
Ar	androgen receptor	0.094
Hoxd10	homeobox D10	0.092
Cdh5	cadherin 5	0.082
Eya1	eyes absent 1 homolog (Drosophila)	0.081
Hoxb9	homeobox B9	0.076
Hoxa7	homeobox A7	0.075	Mouse
Hoxa1	homeobox A1	0.075
Hoxd11	homeobox D11	0.074
Ihh	Indian hedgehog	0.073	Mouse
Gpc3	glypican 3	0.071
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.067
Sox11	SRY-box containing gene 11	0.067	Mouse
Msx2	homeobox, msh-like 2	0.065
Gm13290	predicted gene 13290	0.063
Hoxd8	homeobox D8	0.062	Mouse
Col2a1	collagen, type II, alpha 1	0.062
Eda	ectodysplasin-A	0.061
Rxra	retinoid X receptor alpha	0.060
Trp63	transformation related protein 63	0.059
Fzd8	frizzled homolog 8 (Drosophila)	0.058
Aplnr	apelin receptor	0.058
Ptprb	protein tyrosine phosphatase, receptor type, B	0.057
Lef1	lymphoid enhancer binding factor 1	0.057
Nkx2-1	NK2 homeobox 1	0.056
Cldn5	claudin 5	0.055
Pou3f3	POU domain, class 3, transcription factor 3	0.055
Lrp2	low density lipoprotein receptor-related protein 2	0.054	Mouse
Smad2	MAD homolog 2 (Drosophila)	0.052
Vegfa	vascular endothelial growth factor A	0.051
Foxc2	forkhead box C2	0.050
Hoxc9	homeobox C9	0.048
En1	engrailed 1	0.048
Nf2	neurofibromatosis 2	0.047
Smad3	MAD homolog 3 (Drosophila)	0.044
Efna2	ephrin A2	0.043
Gas1	growth arrest specific 1	0.043
Pthlh	parathyroid hormone-like peptide	0.043
Alx3	aristaless-like homeobox 3	0.043
Hoxc6	homeobox C6	0.043	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.042
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.042
Bnc1	basonuclin 1	0.041
Gli1	GLI-Kruppel family member GLI1	0.041
Col1a1	collagen, type I, alpha 1	0.040
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.039
Tgfbr1	transforming growth factor, beta receptor I	0.039	Mouse
Fgf18	fibroblast growth factor 18	0.039
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.038
She	src homology 2 domain-containing transforming protein E	0.036
Wnt5a	wingless-related MMTV integration site 5A	0.036	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.036
Sox13	SRY-box containing gene 13	0.036
Hoxb8	homeobox B8	0.034	Mouse
Pax9	paired box gene 9	0.034
Efnb2	ephrin B2	0.034
Sox4	SRY-box containing gene 4	0.033	Mouse
Foxa2	forkhead box A2	0.032
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.032
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.032
Amhr2	anti-Mullerian hormone type 2 receptor	0.032	Mouse
Sox18	SRY-box containing gene 18	0.032	Mouse
Tgfa	transforming growth factor alpha	0.031
Wnt1	wingless-related MMTV integration site 1	0.031	Mouse
Stk4	serine/threonine kinase 4	0.031
Crebbp	CREB binding protein	0.030
Tcf15	transcription factor 15	0.029
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.029
Pgr	progesterone receptor	0.029
Hbb-b1	hemoglobin, beta adult major chain	0.029
Hoxa11	homeobox A11	0.029
Isl1	ISL1 transcription factor, LIM/homeodomain	0.028
Ptch1	patched homolog 1	0.028
Gsc	goosecoid homeobox	0.028
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.028
Lrp5	low density lipoprotein receptor-related protein 5	0.027	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.027
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.027
Eng	endoglin	0.026
Raf1	v-raf-leukemia viral oncogene 1	0.026
Upk3b	uroplakin 3B	0.026
Smad7	MAD homolog 7 (Drosophila)	0.026
Sall3	sal-like 3 (Drosophila)	0.026
Meox1	mesenchyme homeobox 1	0.025
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.025
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.025
Srebf2	sterol regulatory element binding factor 2	0.025
Bcl2	B-cell leukemia/lymphoma 2	0.024
Rb1	retinoblastoma 1	0.024
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.024
Pten	phosphatase and tensin homolog	0.024
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.023
Sim2	single-minded homolog 2 (Drosophila)	0.023
Fgf15	fibroblast growth factor 15	0.023
Gpr50	G-protein-coupled receptor 50	0.023
Fgf9	fibroblast growth factor 9	0.023
Fgfrl1	fibroblast growth factor receptor-like 1	0.023
Smad1	MAD homolog 1 (Drosophila)	0.023
Hic1	hypermethylated in cancer 1	0.022
Col4a3	collagen, type IV, alpha 3	0.022
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.022
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.022
Apoe	apolipoprotein E	0.021
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.021
T	brachyury	0.021
Nkx3-2	NK3 homeobox 2	0.021
Edn3	endothelin 3	0.021
Fzd10	frizzled homolog 10 (Drosophila)	0.021
Emx2	empty spiracles homolog 2 (Drosophila)	0.020
Axin2	axin2	0.020
Npr3	natriuretic peptide receptor 3	0.020
Tcfap2c	transcription factor AP-2, gamma	0.020
Hes1	hairy and enhancer of split 1 (Drosophila)	0.020
Fzd1	frizzled homolog 1 (Drosophila)	0.020
Foxf1a	forkhead box F1a	0.019
Fgf23	fibroblast growth factor 23	0.019
Wnt2b	wingless related MMTV integration site 2b	0.019	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.019
Emid1	EMI domain containing 1	0.019
Fgf4	fibroblast growth factor 4	0.019
Sox1	SRY-box containing gene 1	0.019
Gm98	predicted gene 98	0.019
Nynrin	NYN domain and retroviral integrase containing	0.019
Hif1a	hypoxia inducible factor 1, alpha subunit	0.018	Fly
Ldb2	LIM domain binding 2	0.018
Fgf2	fibroblast growth factor 2	0.018
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.018
Vstm2b	V-set and transmembrane domain containing 2B	0.018
Rem1	rad and gem related GTP binding protein 1	0.018
Ppap2b	phosphatidic acid phosphatase type 2B	0.018
Sox3	SRY-box containing gene 3	0.018	Mouse
Pou3f1	POU domain, class 3, transcription factor 1	0.017
Fzd4	frizzled homolog 4 (Drosophila)	0.017
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.017
Sult5a1	sulfotransferase family 5A, member 1	0.017
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.017
Pdgfb	platelet derived growth factor, B polypeptide	0.017
Npas1	neuronal PAS domain protein 1	0.017
Hoxa6	homeobox A6	0.017	Mouse
Hoxd1	homeobox D1	0.017
Bmp5	bone morphogenetic protein 5	0.016
Col11a1	collagen, type XI, alpha 1	0.016
Ptk7	PTK7 protein tyrosine kinase 7	0.016
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.016
Gata3	GATA binding protein 3	0.016
Bmp15	bone morphogenetic protein 15	0.016
Col13a1	collagen, type XIII, alpha 1	0.016
Ank1	ankyrin 1, erythroid	0.016
Dlx6	distal-less homeobox 6	0.015
Rpgrip1l	Rpgrip1-like	0.015
Runx2	runt related transcription factor 2	0.015
Emid2	EMI domain containing 2	0.015
Braf	Braf transforming gene	0.015
Ret	ret proto-oncogene	0.015
Prnp	prion protein	0.015
Meis1	Meis homeobox 1	0.015
Plin1	perilipin 1	0.015
Tbx15	T-box 15	0.014
Diablo	diablo homolog (Drosophila)	0.014
Foxd1	forkhead box D1	0.014
Sox2	SRY-box containing gene 2	0.014	Mouse
Fxyd2	FXYD domain-containing ion transport regulator 2	0.014
Wnt10b	wingless related MMTV integration site 10b	0.013	Mouse
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Cbfb	core binding factor beta	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013
Emp2	epithelial membrane protein 2	0.013
Pitx1	paired-like homeodomain transcription factor 1	0.013
Zic1	zinc finger protein of the cerebellum 1	0.013
Dlx2	distal-less homeobox 2	0.013
Srpx	sushi-repeat-containing protein	0.013
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.013	Mouse
Zfp771	zinc finger protein 771	0.013
Tgfb1	transforming growth factor, beta 1	0.013
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.013
Lbx2	ladybird homeobox homolog 2 (Drosophila)	0.013
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.012
Dlg1	discs, large homolog 1 (Drosophila)	0.012
Gata6	GATA binding protein 6	0.012
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.012
Npc1	Niemann Pick type C1	0.012
Zfp185	zinc finger protein 185	0.012
Smad5	MAD homolog 5 (Drosophila)	0.012
Cldn1	claudin 1	0.012
Inhbb	inhibin beta-B	0.012
Ccnd1	cyclin D1	0.012
Ece1	endothelin converting enzyme 1	0.012
Glra1	glycine receptor, alpha 1 subunit	0.012
Cib2	calcium and integrin binding family member 2	0.012
Uncx	UNC homeobox	0.012
Sertad2	SERTA domain containing 2	0.012
Fzd7	frizzled homolog 7 (Drosophila)	0.012
Wt1	Wilms tumor 1 homolog	0.012
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Tenc1	tensin like C1 domain-containing phosphatase	0.011
Tert	telomerase reverse transcriptase	0.011
Gdf1	growth differentiation factor 1	0.011	Mouse
Nrtn	neurturin	0.011
Robo3	roundabout homolog 3 (Drosophila)	0.011
Tsc2	tuberous sclerosis 2	0.011
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.011
Bmp6	bone morphogenetic protein 6	0.011
Lhx6	LIM homeobox protein 6	0.011
Wnt5b	wingless-related MMTV integration site 5B	0.011	Mouse
Itga8	integrin alpha 8	0.011
Rint1	RAD50 interactor 1	0.011
Zfp651	zinc finger protein 651	0.011
Wls	wntless homolog (Drosophila)	0.011
Dmpk	dystrophia myotonica-protein kinase	0.011
Tead3	TEA domain family member 3	0.011
Bmper	BMP-binding endothelial regulator	0.011
Des	desmin	0.011
Ctf1	cardiotrophin 1	0.010
Pax6	paired box gene 6	0.010
Shox2	short stature homeobox 2	0.010
Vcl	vinculin	0.010
Lrp4	low density lipoprotein receptor-related protein 4	0.010	Mouse
Hoxa13	homeobox A13	0.010
Mn1	meningioma 1	0.010
Epor	erythropoietin receptor	0.010
Adra2c	adrenergic receptor, alpha 2c	0.010
Prx	periaxin	0.010
Tsc22d3	TSC22 domain family, member 3	0.010
Wnt3	wingless-related MMTV integration site 3	0.010	Mouse
Plac1	placental specific protein 1	0.010
Zfp703	zinc finger protein 703	0.010
Idua	iduronidase, alpha-L-	0.010
Ext1	exostoses (multiple) 1	0.010