IMP

Process View

Mus musculus

3 genes annotated in mouse

regulation of ureteric bud formation

Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of ureteric bud formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of ureteric bud formation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	1.000
Pitx2	paired-like homeodomain transcription factor 2	1.000
Fgf8	fibroblast growth factor 8	1.000
Eya1	eyes absent 1 homolog (Drosophila)	1.000
Tbx1	T-box 1	0.999
Hoxa1	homeobox A1	0.999
Shh	sonic hedgehog	0.998
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.994
Gata4	GATA binding protein 4	0.994	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.993
Jag1	jagged 1	0.993
Rarg	retinoic acid receptor, gamma	0.986
Gli3	GLI-Kruppel family member GLI3	0.985
Gata6	GATA binding protein 6	0.981	Mouse
Bmp4	bone morphogenetic protein 4	0.977
Hand2	heart and neural crest derivatives expressed transcript 2	0.973
Vegfa	vascular endothelial growth factor A	0.973
Isl1	ISL1 transcription factor, LIM/homeodomain	0.972
Rxra	retinoid X receptor alpha	0.963
Pax3	paired box gene 3	0.961
Foxc1	forkhead box C1	0.960
Foxc2	forkhead box C2	0.958
Tcfap2a	transcription factor AP-2, alpha	0.941
Msx1	homeobox, msh-like 1	0.936
Fgf10	fibroblast growth factor 10	0.916
Hoxa2	homeobox A2	0.915
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.900
Tgfb2	transforming growth factor, beta 2	0.889
Chd7	chromodomain helicase DNA binding protein 7	0.880
Sox2	SRY-box containing gene 2	0.843
Tbx3	T-box 3	0.760
Gbx2	gastrulation brain homeobox 2	0.738
Hand1	heart and neural crest derivatives expressed transcript 1	0.718
Sox9	SRY-box containing gene 9	0.716
Foxg1	forkhead box G1	0.708
Smo	smoothened homolog (Drosophila)	0.667
Ednra	endothelin receptor type A	0.644
Bmp7	bone morphogenetic protein 7	0.626
Bnc1	basonuclin 1	0.626
Prrx1	paired related homeobox 1	0.618
Chrd	chordin	0.614
Efnb2	ephrin B2	0.609
Gata5	GATA binding protein 5	0.607	Mouse
Ntf3	neurotrophin 3	0.602
Wt1	Wilms tumor 1 homolog	0.599
Tead3	TEA domain family member 3	0.570
Smad6	MAD homolog 6 (Drosophila)	0.551
Hoxa3	homeobox A3	0.548
Tbx2	T-box 2	0.545
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.498
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.496
Zfpm2	zinc finger protein, multitype 2	0.468
Prrx2	paired related homeobox 2	0.466
Foxf1a	forkhead box F1a	0.460
Pbx1	pre B-cell leukemia transcription factor 1	0.433
Fgf3	fibroblast growth factor 3	0.429
Ptk7	PTK7 protein tyrosine kinase 7	0.426
Gsc	goosecoid homeobox	0.407
Rarb	retinoic acid receptor, beta	0.401
Gata3	GATA binding protein 3	0.399
Hoxb3	homeobox B3	0.381
Mesp1	mesoderm posterior 1	0.379
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.352	Mouse
Gli2	GLI-Kruppel family member GLI2	0.347
Nos3	nitric oxide synthase 3, endothelial cell	0.340
Hoxa4	homeobox A4	0.330
Otx2	orthodenticle homolog 2 (Drosophila)	0.318
Nynrin	NYN domain and retroviral integrase containing	0.289
Sim2	single-minded homolog 2 (Drosophila)	0.271
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.269
Nog	noggin	0.254
Hmx3	H6 homeobox 3	0.242
Efna2	ephrin A2	0.242
Sox7	SRY-box containing gene 7	0.237
Lmx1a	LIM homeobox transcription factor 1 alpha	0.233
Fgfr1	fibroblast growth factor receptor 1	0.232
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.223
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.222
Pax8	paired box gene 8	0.219
Hes1	hairy and enhancer of split 1 (Drosophila)	0.216
Emx2	empty spiracles homolog 2 (Drosophila)	0.214
Hoxd3	homeobox D3	0.210
Tcfap2c	transcription factor AP-2, gamma	0.207
Hoxb4	homeobox B4	0.191
Acvr1	activin A receptor, type 1	0.188
Snai1	snail homolog 1 (Drosophila)	0.179
Klf3	Kruppel-like factor 3 (basic)	0.176
Bcl2	B-cell leukemia/lymphoma 2	0.175
Otx1	orthodenticle homolog 1 (Drosophila)	0.172
Rara	retinoic acid receptor, alpha	0.167
Hoxc8	homeobox C8	0.165
Hoxd13	homeobox D13	0.154
Lhx1	LIM homeobox protein 1	0.151
Dlx5	distal-less homeobox 5	0.150
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.150
Hoxd9	homeobox D9	0.150
Ece1	endothelin converting enzyme 1	0.146
Wnt6	wingless-related MMTV integration site 6	0.146
Pitx1	paired-like homeodomain transcription factor 1	0.140
Hoxa13	homeobox A13	0.133
Wnt3a	wingless-related MMTV integration site 3A	0.132
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.127
Gpc3	glypican 3	0.125
Foxd2	forkhead box D2	0.121
Tbx10	T-box 10	0.118
Lef1	lymphoid enhancer binding factor 1	0.117
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.115
Emid2	EMI domain containing 2	0.115
Zeb1	zinc finger E-box binding homeobox 1	0.109
Twist2	twist homolog 2 (Drosophila)	0.109
Tcf21	transcription factor 21	0.109
Msx2	homeobox, msh-like 2	0.106
Ephb2	Eph receptor B2	0.106
Gja5	gap junction protein, alpha 5	0.101
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.100
Wnt11	wingless-related MMTV integration site 11	0.096
Ar	androgen receptor	0.093
Hoxb6	homeobox B6	0.092
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.092
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.090
Col4a3	collagen, type IV, alpha 3	0.088
Lama5	laminin, alpha 5	0.088
Fgf18	fibroblast growth factor 18	0.087
Hoxa10	homeobox A10	0.085
Lmx1b	LIM homeobox transcription factor 1 beta	0.085
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.084
Myl7	myosin, light polypeptide 7, regulatory	0.084
Fzd8	frizzled homolog 8 (Drosophila)	0.083
Col2a1	collagen, type II, alpha 1	0.080
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.080
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.080
Foxf2	forkhead box F2	0.078
Hoxd11	homeobox D11	0.078
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.077
Efnb1	ephrin B1	0.076
Sox4	SRY-box containing gene 4	0.075
Ctf1	cardiotrophin 1	0.073
Fbn2	fibrillin 2	0.072
Des	desmin	0.072
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.071
Wnt4	wingless-related MMTV integration site 4	0.069
Gdnf	glial cell line derived neurotrophic factor	0.067	Human Rat
Nfia	nuclear factor I/A	0.065
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.065
Hoxb1	homeobox B1	0.064
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.064
Npr1	natriuretic peptide receptor 1	0.063
Dll1	delta-like 1 (Drosophila)	0.063
Hoxa5	homeobox A5	0.063
Efna5	ephrin A5	0.062
Ppara	peroxisome proliferator activated receptor alpha	0.061
Tal1	T-cell acute lymphocytic leukemia 1	0.061
Gli1	GLI-Kruppel family member GLI1	0.060
Notch1	Notch gene homolog 1 (Drosophila)	0.060
Sox11	SRY-box containing gene 11	0.060
Hmga2	high mobility group AT-hook 2	0.058
Gja1	gap junction protein, alpha 1	0.057
T	brachyury	0.055
En1	engrailed 1	0.055
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.053
Hrc	histidine rich calcium binding protein	0.052
Tbx15	T-box 15	0.052
Irx3	Iroquois related homeobox 3 (Drosophila)	0.051
Vangl2	vang-like 2 (van gogh, Drosophila)	0.051
Wnt1	wingless-related MMTV integration site 1	0.051
Foxa1	forkhead box A1	0.051
Nrk	Nik related kinase	0.051
Cldn3	claudin 3	0.051
Eya4	eyes absent 4 homolog (Drosophila)	0.048
Twist1	twist homolog 1 (Drosophila)	0.048
Hoxa11	homeobox A11	0.047
Efna4	ephrin A4	0.047
Zfp503	zinc finger protein 503	0.047
Npr3	natriuretic peptide receptor 3	0.046
Lrp2	low density lipoprotein receptor-related protein 2	0.045
Zfp771	zinc finger protein 771	0.045
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.045
Gata2	GATA binding protein 2	0.045	Mouse
Foxa2	forkhead box A2	0.044
Capn6	calpain 6	0.044
Hoxc4	homeobox C4	0.044
Phox2a	paired-like homeobox 2a	0.041
Hoxb5	homeobox B5	0.041
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.041
Sall4	sal-like 4 (Drosophila)	0.040
Zfp185	zinc finger protein 185	0.040
Gpr50	G-protein-coupled receptor 50	0.040
Axin2	axin2	0.038
Actn2	actinin alpha 2	0.038
Hmx1	H6 homeobox 1	0.038
Ppl	periplakin	0.037
Plac1	placental specific protein 1	0.037
Epha1	Eph receptor A1	0.037
Hoxd4	homeobox D4	0.036
Pitx3	paired-like homeodomain transcription factor 3	0.036
Ebf3	early B-cell factor 3	0.036
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.035
Mmp11	matrix metallopeptidase 11	0.035
Tlx2	T-cell leukemia, homeobox 2	0.035
Tmprss2	transmembrane protease, serine 2	0.035
Stc2	stanniocalcin 2	0.034
Jag2	jagged 2	0.033
Neurog1	neurogenin 1	0.033
Hoxa9	homeobox A9	0.032
Zfp316	zinc finger protein 316	0.032
Wnt2b	wingless related MMTV integration site 2b	0.032
Hoxd1	homeobox D1	0.032
Lhx3	LIM homeobox protein 3	0.032
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.031
Irs3	insulin receptor substrate 3	0.031
Hes5	hairy and enhancer of split 5 (Drosophila)	0.030
Crlf1	cytokine receptor-like factor 1	0.030
Nrtn	neurturin	0.029
Bdnf	brain derived neurotrophic factor	0.029
Tead2	TEA domain family member 2	0.029
Dusp9	dual specificity phosphatase 9	0.028
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.027
Sult5a1	sulfotransferase family 5A, member 1	0.027
Lhx9	LIM homeobox protein 9	0.027
Nf1	neurofibromatosis 1	0.027
Dlx1	distal-less homeobox 1	0.027
Chad	chondroadherin	0.027
Alx4	aristaless-like homeobox 4	0.026
Gjb5	gap junction protein, beta 5	0.025
Tcf15	transcription factor 15	0.025
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.025
Mecom	MDS1 and EVI1 complex locus	0.025
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.025
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.025
Hic1	hypermethylated in cancer 1	0.025
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.024
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.024
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.024
Tgfbr2	transforming growth factor, beta receptor II	0.024
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.024
Col13a1	collagen, type XIII, alpha 1	0.024
Wiz	widely-interspaced zinc finger motifs	0.024
Tead1	TEA domain family member 1	0.024
Eya2	eyes absent 2 homolog (Drosophila)	0.023
Irx5	Iroquois related homeobox 5 (Drosophila)	0.023
Phlda2	pleckstrin homology-like domain, family A, member 2	0.023
Wnt10b	wingless related MMTV integration site 10b	0.023
Egfr	epidermal growth factor receptor	0.023
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.023
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.023
Neo1	neogenin	0.023
Hoxb9	homeobox B9	0.022
Fzd4	frizzled homolog 4 (Drosophila)	0.022
Fzd7	frizzled homolog 7 (Drosophila)	0.022
Amh	anti-Mullerian hormone	0.022
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.022
Sh3pxd2a	SH3 and PX domains 2A	0.021
Tgif2	TGFB-induced factor homeobox 2	0.021
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Notch3	Notch gene homolog 3 (Drosophila)	0.021
Epha2	Eph receptor A2	0.021
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.021
Ephb3	Eph receptor B3	0.020
Sim1	single-minded homolog 1 (Drosophila)	0.020
Smad3	MAD homolog 3 (Drosophila)	0.020
Itga3	integrin alpha 3	0.020
Creb3l1	cAMP responsive element binding protein 3-like 1	0.019
Krt15	keratin 15	0.019
Sall3	sal-like 3 (Drosophila)	0.019
Actn3	actinin alpha 3	0.019
Pax6	paired box gene 6	0.019
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.019
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.018
Foxa3	forkhead box A3	0.018
Ldb3	LIM domain binding 3	0.018
Hoxc5	homeobox C5	0.018
Wnt5b	wingless-related MMTV integration site 5B	0.018
Msi1	Musashi homolog 1(Drosophila)	0.018
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.018
Fosl2	fos-like antigen 2	0.018
Hoxa7	homeobox A7	0.018
Meox2	mesenchyme homeobox 2	0.018
Zfpm1	zinc finger protein, multitype 1	0.018
Tbx4	T-box 4	0.018
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.017
Inha	inhibin alpha	0.017
Neurog3	neurogenin 3	0.017
Dhh	desert hedgehog	0.017
Cxcr7	chemokine (C-X-C motif) receptor 7	0.017
Bik	BCL2-interacting killer	0.017
Adra2b	adrenergic receptor, alpha 2b	0.017
Hnf1b	HNF1 homeobox B	0.017
Cd151	CD151 antigen	0.017
Insm1	insulinoma-associated 1	0.016
Yap1	yes-associated protein 1	0.016
Hoxd10	homeobox D10	0.016
Fgfr3	fibroblast growth factor receptor 3	0.016
Kcnk3	potassium channel, subfamily K, member 3	0.016
Mark1	MAP/microtubule affinity-regulating kinase 1	0.016
Mogat2	monoacylglycerol O-acyltransferase 2	0.015
Slc38a5	solute carrier family 38, member 5	0.015
Nkx6-1	NK6 homeobox 1	0.015
Lama1	laminin, alpha 1	0.015
Jarid2	jumonji, AT rich interactive domain 2	0.015
Gpr97	G protein-coupled receptor 97	0.015
Lrp5	low density lipoprotein receptor-related protein 5	0.015
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.015
Dlx2	distal-less homeobox 2	0.015
Ppfibp2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.015
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.015
Ank1	ankyrin 1, erythroid	0.015
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.015
Ret	ret proto-oncogene	0.014
Unc5c	unc-5 homolog C (C. elegans)	0.014
Phf7	PHD finger protein 7	0.014
Fam83h	family with sequence similarity 83, member H	0.014
Efs	embryonal Fyn-associated substrate	0.014
Foxi3	forkhead box I3	0.014
Col22a1	collagen, type XXII, alpha 1	0.014
Mmp15	matrix metallopeptidase 15	0.014
Sdk2	sidekick homolog 2 (chicken)	0.014
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.014
Tert	telomerase reverse transcriptase	0.014
Krt14	keratin 14	0.014
Dmpk	dystrophia myotonica-protein kinase	0.014
Cic	capicua homolog (Drosophila)	0.014
Aes	amino-terminal enhancer of split	0.014
Xirp1	xin actin-binding repeat containing 1	0.013
Atoh8	atonal homolog 8 (Drosophila)	0.013
Gjb4	gap junction protein, beta 4	0.013
Wnt3	wingless-related MMTV integration site 3	0.013
Prph	peripherin	0.013
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.013
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.013
Fbln1	fibulin 1	0.013
Wfdc2	WAP four-disulfide core domain 2	0.013
Irx1	Iroquois related homeobox 1 (Drosophila)	0.013
Gypa	glycophorin A	0.013
Edn3	endothelin 3	0.013
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.013
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.013
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.013
Ihh	Indian hedgehog	0.013
Dach1	dachshund 1 (Drosophila)	0.013
Sfxn2	sideroflexin 2	0.013
Efna1	ephrin A1	0.013
Lpar3	lysophosphatidic acid receptor 3	0.012
Krt7	keratin 7	0.012
Fhdc1	FH2 domain containing 1	0.012
Barx1	BarH-like homeobox 1	0.012
Gata1	GATA binding protein 1	0.012	Mouse
Vipr1	vasoactive intestinal peptide receptor 1	0.012
Sox17	SRY-box containing gene 17	0.012
Podxl	podocalyxin-like	0.012
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Zbtb46	zinc finger and BTB domain containing 46	0.012
Hoxb2	homeobox B2	0.012
Igsf9	immunoglobulin superfamily, member 9	0.012
Grb10	growth factor receptor bound protein 10	0.012
Dll4	delta-like 4 (Drosophila)	0.012
Rspo1	R-spondin homolog (Xenopus laevis)	0.012
Spry4	sprouty homolog 4 (Drosophila)	0.012
Pax9	paired box gene 9	0.012
Fstl3	follistatin-like 3	0.012
Sost	sclerostin	0.012
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.012
Sox3	SRY-box containing gene 3	0.011
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.011
Hoxd8	homeobox D8	0.011
Ephb4	Eph receptor B4	0.011
Ptrf	polymerase I and transcript release factor	0.011
Sox13	SRY-box containing gene 13	0.011
C77080	expressed sequence C77080	0.011
Mapk12	mitogen-activated protein kinase 12	0.011
Fgf15	fibroblast growth factor 15	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	0.011
She	src homology 2 domain-containing transforming protein E	0.011
Pou3f1	POU domain, class 3, transcription factor 1	0.011
Obsl1	obscurin-like 1	0.011
Barhl2	BarH-like 2 (Drosophila)	0.011
Ano1	anoctamin 1, calcium activated chloride channel	0.011
Prdm6	PR domain containing 6	0.011
Cldn8	claudin 8	0.011
Tead4	TEA domain family member 4	0.011
Hoxc6	homeobox C6	0.011
Meis2	Meis homeobox 2	0.011
Srgap1	SLIT-ROBO Rho GTPase activating protein 1	0.011
Pcdh1	protocadherin 1	0.011
Irx4	Iroquois related homeobox 4 (Drosophila)	0.010
Ncs1	neuronal calcium sensor 1	0.010
Ckmt2	creatine kinase, mitochondrial 2	0.010
Cst9	cystatin 9	0.010
Pvrl2	poliovirus receptor-related 2	0.010
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.010
Mlph	melanophilin	0.010
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.010
Dsg2	desmoglein 2	0.010
Baiap2l1	BAI1-associated protein 2-like 1	0.010
Barx2	BarH-like homeobox 2	0.010
Zfp768	zinc finger protein 768	0.010
Plxna1	plexin A1	0.010