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Danio rerio

2 genes annotated in zebrafish

regulation of cell killing

Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cell killing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cell killing" (in gray)

Name	Description	Probability	Func Analog Organism
zgc:64115	zgc:64115	0.390
polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.231
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.132
trim25	tripartite motif-containing 25	0.077
LOC566020	Gig2-like protein DreO	0.077
scarb1	scavenger receptor class B, member 1	0.073
twist1b	twist1b	0.064
lrrc33	leucine rich repeat containing 33	0.063
yrk	Yes-related kinase	0.062
LOC100535854	ubiquitin carboxyl-terminal hydrolase CYLD-like	0.058
hbbe1.1	hemoglobin beta embryonic-1.1	0.056
casp8	caspase 8, apoptosis-related cysteine peptidase	0.052
npy4r	neuropeptide Y receptor Y4	0.052
fcho2	FCH domain only 2	0.048
zgc:174863	zgc:174863	0.047
stat1a	signal transduction and activation of transcription 1a	0.045
fas	Fas (TNF receptor superfamily, member 6)	0.040
tfap2e	transcription factor AP-2 epsilon	0.038
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.036
grna	granulin a	0.035
zgc:162964	zgc:162964	0.035
pax7b	paired box gene 7b	0.034
sqstm1	sequestosome 1	0.034
zgc:162329	zgc:162329	0.033
stat1b	signal transducer and activator of transcription 1b	0.032
ifnphi1	interferon phi 1	0.032
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.032
apaf1	apoptotic protease activating factor 1	0.029
etnk1	ethanolamine kinase 1	0.029
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.029
zgc:101598	zgc:101598	0.028
asah1b	N-acylsphingosine amidohydrolase (acid ceramidase) 1b	0.028
defbl3	defensin, beta-like 3	0.028
g6pd	glucose-6-phosphate dehydrogenase	0.028
ugt5c2	UDP glucuronosyltransferase 5 family, polypeptide C2	0.028
irf11	interferon regulatory factor 11	0.027
pkz	protein kinase containing Z-DNA binding domains	0.027
spns2	spinster homolog 2 (Drosophila)	0.026
mcl1a	myeloid cell leukemia sequence 1a	0.026
c1qb	complement component 1, q subcomponent, B chain	0.025
impdh1b	inosine 5'-phosphate dehydrogenase 1b	0.025
cxcr3.2	chemokine (C-X-C motif) receptor 3.2	0.025
LOC792676	similar to N-myc-interactor (Nmi) (N-myc and STAT interactor)	0.025
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.025
pygmb	phosphorylase, glycogen (muscle) b	0.025
arl4aa	ADP-ribosylation factor-like 4aa	0.025
styk1	serine/threonine/tyrosine kinase 1	0.024
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.024
cflar	CASP8 and FADD-like apoptosis regulator	0.024
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.023
gsk3b	glycogen synthase kinase 3 beta	0.022
col5a3	collagen, type V, alpha 3	0.022
c3c	complement component c3c	0.022
hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.021
ugt5a2	UDP glucuronosyltransferase 5 family, polypeptide A2	0.021
psmb9a	proteasome (prosome, macropain) subunit, beta type, 9a	0.021
npy7r	neuropeptide Y receptor Y7	0.021
cnnm2a	cyclin M2a	0.021
waca	WW domain containing adaptor with coiled-coil a	0.021
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.021
sp8b	sp8 transcription factor b	0.021
mep1a.1	meprin A, alpha.1	0.021
casp9	caspase 9, apoptosis-related cysteine protease	0.020
c1qc	complement component 1, q subcomponent, C chain	0.020
ifi35	interferon-induced protein 35	0.020
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.020
nos2a	nitric oxide synthase 2a, inducible	0.020
tlr4bb	toll-like receptor 4b, duplicate b	0.020
gnsb	glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b	0.020
isg15	ISG15 ubiquitin-like modifier	0.019
sdcbp	syndecan binding protein (syntenin)	0.019
mxa	myxovirus (influenza) resistance A	0.019
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.019
nitr8	novel immune-type receptor 8	0.019
gpr137bb	G protein-coupled receptor 137bb	0.019
slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.019
si:ch211-244b2.4	si:ch211-244b2.4	0.019
kpna3	karyopherin (importin) alpha 3	0.019
itln1	intelectin 1	0.019
c3b	complement component c3b	0.018
zgc:171538	zgc:171538	0.018
illr1	immune-related, lectin-like receptor 1	0.018	Zebrafish
LOC100005232	Gig2-like protein DreD	0.018
ip6k2	inositol hexaphosphate kinase 2	0.018
pttg1ipb	pituitary tumor-transforming 1 interacting protein b	0.018
fadd	Fas (tnfrsf6)-associated via death domain	0.017
gbp1	guanylate binding protein 1	0.017
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.017
sb:cb134	sb:cb134	0.017
il12bb	interleukin 12B, b	0.017	Mouse
csf1ra	colony stimulating factor 1 receptor, a	0.017
irgq1	immunity-related GTPase family, q1	0.017
nitr4a	novel immune-type receptor 4a	0.017
LOC100005454	Gig2-like protein DreK	0.017
fxr2	fragile X mental retardation, autosomal homolog 2	0.017
lats1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.017
cd209	CD209 molecule	0.017	Zebrafish
slc12a10.1	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.1	0.017
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.017
zgc:92313	zgc:92313	0.017
tlr9	toll-like receptor 9	0.017
gpr22	G protein-coupled receptor 22	0.017
plekha7	pleckstrin homology domain containing, family A member 7	0.016
zgc:110789	zgc:110789	0.016
vps39	vacuolar protein sorting 39 homolog (S. cerevisiae)	0.016
ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.016
fbln4	fibulin 4	0.016
il10	interleukin 10	0.016
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.016
itk	IL2-inducible T-cell kinase	0.016
irak4	interleukin-1 receptor-associated kinase 4	0.016
rabep1	rabaptin, RAB GTPase binding effector protein 1	0.016
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.015
tpsn	tapasin	0.015
tbx21	T-box 21	0.015
faf2	Fas associated factor family member 2	0.015
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.015
mtmr8	myotubularin related protein 8	0.015
psme2	proteasome activator subunit 2	0.015
trim55b	tripartite motif-containing 55b	0.015
rab5c	RAB5C, member RAS oncogene family	0.015
gab1	GRB2-associated binding protein 1	0.015
nitr12	novel immune-type receptor 12	0.015
npepps	aminopeptidase puromycin sensitive	0.015
si:dkey-151c10.1	si:dkey-151c10.1	0.014
zgc:100915	zgc:100915	0.014
cd8a	CD8 antigen, alpha polypeptide	0.014
tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.014
ggnbp2	gametogenetin binding protein 2	0.014
adprhl1	ADP-ribosylhydrolase like 1	0.014
amh	anti-Mullerian hormone	0.014
LOC793458	peptide Y-like	0.014
bmf1	Bcl2 modifying factor 1	0.014
eomesb	eomesodermin homolog b	0.014
taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto	0.014
LOC794786	interferon-induced protein with tetratricopeptide repeats 1-like	0.014
abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.014
crfb17	cytokine receptor family member B17	0.014
zgc:66100	zgc:66100	0.014
k31	k31 gene	0.014
egr2a	early growth response 2a	0.014
ptger2b	prostaglandin E receptor 2b (subtype EP2)	0.014
stat6	signal transducer and activator of transcription 6, interleukin-4 induced	0.014
znf148	zinc finger protein 148	0.013
crfa31.2	IL-4RA-like protein 2	0.013
id:ibd5104	id:ibd5104	0.013
tp53bp2	tumor protein p53 binding protein, 2	0.013
cpne1	copine I	0.013
robo4	roundabout homolog 4	0.013
cd40lg	CD40 ligand	0.013
mipa	major intrinsic protein of lens fiber a	0.013
pdcd6ip	programmed cell death 6 interacting protein	0.013
cxc46	CXC chemokine 46	0.013
zgc:110775	zgc:110775	0.013
foxp3a	forkhead box P3a	0.013
b4galt5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	0.013
LOC100005283	Gig2-like protein DreE	0.013
hdac4	histone deacetylase 4	0.013
baxa	bcl2-associated X protein, a	0.013
ptprma	protein tyrosine phosphatase, receptor type, M, a	0.013
grk5	G protein-coupled receptor kinase 5	0.013
il17a/f2	interleukin 17a/f2	0.013
greb1	growth regulation by estrogen in breast cancer 1	0.013
sult2st1	sulfotransferase family 2, cytosolic sulfotransferase 1	0.013
b4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.013
gstal	glutathione S-transferase, alpha-like	0.013
LOC566708	FL cytokine receptor-like	0.013
tlr22	toll-like receptor 22	0.013
LOC567441	interferon-induced protein with tetratricopeptide repeats 5-like	0.013
si:ch73-9j13.1	si:ch73-9j13.1	0.012
psma6b	proteasome (prosome, macropain) subunit, alpha type, 6b	0.012
illr3	immune-related, lectin-like receptor 3	0.012
crfb13	cytokine receptor family member b13	0.012
zgc:153286	zgc:153286	0.012
cx34.4	connexin 34.4	0.012
rnd1l	Rho family GTPase 1 like	0.012
zgc:63629	zgc:63629	0.012
tfe3a	transcription factor binding to IGHM enhancer 3a	0.012
LOC100534776	toll-like receptor 7-like	0.012
igfbp2b	insulin-like growth factor binding protein 2b	0.012
cd40	CD40 antigen	0.012
rps6ka3a	ribosomal protein S6 kinase, polypeptide 3a	0.012
caspb	caspase b and caspase b-like	0.012
LOC100000934	hypothetical protein LOC100000934	0.012
pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.012
nitr13	novel immune-type receptor 13	0.012
zgc:63831	zgc:63831	0.012
snx5	sorting nexin 5	0.012
zgc:56194	zgc:56194	0.012
si:ch211-170d8.2	si:ch211-170d8.2	0.012
LOC563316	similar to Ap3b1 protein	0.012
il22	interleukin 22	0.012
jak2a	Janus kinase 2a	0.012
nos1	nitric oxide synthase 1 (neuronal)	0.012
adrb2a	adrenergic receptor, beta 2a	0.012
sec31b	Sec31 homolog B (S. cerevisiae)	0.012
chmp1a	chromatin modifying protein 1A	0.012
wnt5a	wingless-type MMTV integration site family, member 5a	0.012
tspo	translocator protein	0.012
zgc:103710	zgc:103710	0.012
fth1a	ferritin, heavy polypeptide 1a	0.012
atoh8	atonal homolog 8	0.012
tm9sf1	transmembrane 9 superfamily member 1	0.012
sb:cb183	sb:cb183	0.012
rab22a	RAB22A, member RAS oncogene family	0.012
si:dkeyp-117b8.3	si:dkeyp-117b8.3	0.012
tax1bp1b	Tax1 (human T-cell leukemia virus type I) binding protein 1b	0.012
gltscr1	glioma tumor suppressor candidate region gene 1	0.012
lyrm1	LYR motif containing 1	0.011
gabarapa	GABA(A) receptor-associated protein a	0.011
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.011
gna13b	guanine nucleotide binding protein (G protein), alpha 13b	0.011
map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.011
irgf1	immunity-related GTPase family, f1	0.011
cyp2v2	cytochrome P450, family 2, subfamily V, polypeptide 2	0.011
nitr5	novel immune-type receptor 5 and immune-type receptor 5-like	0.011
phrf1	PHD and ring finger domains 1	0.011
ptk6a	PTK6 protein tyrosine kinase 6a	0.011
zgc:172101	zgc:172101	0.011
zap70	zeta-chain (TCR) associated protein kinase	0.011
camk2g2	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2	0.011
ugt2a6	UDP glucuronosyltransferase 2 family, polypeptide A6	0.011
pax5	paired box gene 5	0.011
zgc:92745	zgc:92745	0.011
serinc5	serine incorporator 5	0.011
ugt2b6	UDP glucuronosyltransferase 2 family, polypeptide B6	0.011
abat	4-aminobutyrate aminotransferase	0.011
zfyve28	zinc finger, FYVE domain containing 28	0.011
atp2b1b	ATPase, Ca++ transporting, plasma membrane 1b	0.011
c10orf11	c10orf11 homolog (H. sapiens)	0.011
pou5f1	POU domain, class 5, transcription factor 1	0.011
ugt5f1	UDP glucuronosyltransferase 5 family, polypeptide F1	0.011
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.011
calcr	calcitonin receptor	0.011
zgc:153941	zgc:153941	0.011
sipa1l1	signal-induced proliferation-associated 1 like 1	0.011
LOC100148845	neurogenin-1-like	0.011
tlr8b	toll-like receptor 8b	0.011
irf7	interferon regulatory factor 7	0.011
pbxip1b	pre-B-cell leukemia homeobox interacting protein 1b	0.011
mef2a	myocyte enhancer factor 2a	0.011
ccnt2a	cyclin T2a	0.011
acsl3a	acyl-CoA synthetase long-chain family member 3a	0.011
tlr4ba	toll-like receptor 4b, duplicate a	0.011
ap1m2	adaptor-related protein complex 1, mu 2 subunit	0.011
irgq2	immunity-related GTPase family, q2	0.011
si:ch73-13b6.3	si:ch73-13b6.3	0.011
f2r	coagulation factor II (thrombin) receptor	0.011
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.011
rab5ab	RAB5A, member RAS oncogene family, b	0.010
mfsd4a	major facilitator superfamily domain containing 4a	0.010
elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	0.010
syngr1a	synaptogyrin 1a	0.010
insra	insulin receptor a	0.010
zgc:123282	zgc:123282	0.010
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.010
gpr143	G protein-coupled receptor 143	0.010
npsnl	nephrosin-like	0.010
myb	myeloblastosis oncogene	0.010
tead1a	TEA domain family member 1a	0.010
chmp5	chromatin modifying protein 5	0.010
aida	axin interaction partner and dorsalization antagonist	0.010
tead3a	TEA domain family member 3 a	0.010
LOC561406	prostacyclin receptor-like	0.010
eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.010
kctd9	potassium channel tetramerisation domain containing 9	0.010
bc2	putative breast adenocarcinoma marker	0.010
slc2a1b	solute carrier family 2 (facilitated glucose transporter), member 1b	0.010
gch2	GTP cyclohydrolase 2	0.010
cd247l	CD247 antigen like	0.010
jak1	Janus kinase 1	0.010
plaua	plasminogen activator, urokinase a	0.010
zgc:153921	zgc:153921	0.010
LOC100535646	hypothetical protein LOC100535646	0.010
foxq1b	forkhead box Q1b	0.010
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.010
tfec	transcription factor EC	0.010
syk	spleen tyrosine kinase	0.010
LOC100535549	cytoplasmic polyadenylation element-binding protein 4-like	0.010