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Process View

Danio rerio

1 genes annotated in zebrafish

smooth muscle tissue development

The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "smooth muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "smooth muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
prdm1a	PR domain containing 1a, with ZNF domain	0.691
bmp2b	bone morphogenetic protein 2b	0.681
sox9a	SRY-box containing gene 9a	0.449	Mouse
cdh2	cadherin 2, neuronal	0.397
pax2a	paired box gene 2a	0.301
dlx3b	distal-less homeobox gene 3b	0.295
shha	sonic hedgehog a	0.277	Mouse
foxd3	forkhead box D3	0.181
col2a1a	collagen type II, alpha-1a	0.157
foxa2	forkhead box A2	0.116
foxa3	forkhead box A3	0.111
ptch2	patched 2	0.110
th	tyrosine hydroxylase	0.105
extl3	exostoses (multiple)-like 3	0.095
cdh1	cadherin 1, epithelial	0.095
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.091
mef2d	myocyte enhancer factor 2d	0.086
foxi1	forkhead box I1	0.074
myod1	myogenic differentiation 1	0.067
pcdh8	protocadherin 8	0.067
furina	furin (paired basic amino acid cleaving enzyme) a	0.066
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.063
acvr1b	activin A receptor, type IB	0.062
twist2	twist2	0.060
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.058
dusp1	dual specificity phosphatase 1	0.056
lhx2b	LIM homeobox 2b	0.054
nf1a	neurofibromin 1a	0.051	Mouse
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.049
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.048
sox10	SRY-box containing gene 10	0.046
zeb2b	zinc finger E-box binding homeobox 2b	0.046
eya1	eyes absent homolog 1	0.045
otpa	orthopedia homolog a	0.045
bhlhe41	basic helix-loop-helix family, member e41	0.044
dlx5a	distal-less homeobox gene 5a	0.043
oprd1b	opioid receptor, delta 1b	0.041
tcf12	transcription factor 12	0.041
barhl2	BarH-like 2	0.040
tbx1	T-box 1	0.040
tbx2b	T-box 2b	0.039
hoxc4a	homeo box C4a	0.038
foxj1b	forkhead box J1b	0.037
dusp6	dual specificity phosphatase 6	0.036
tsc22d3	TSC22 domain family, member 3	0.035
s1pr2	sphingosine-1-phosphate receptor 2	0.035
admp	anti-dorsalizing morphogenic protein	0.035
tfap2a	transcription factor AP-2 alpha	0.034
sox8	SRY-box containing gene 8	0.033
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.033
csnk1db	casein kinase 1, delta b	0.032
nf1b	neurofibromin 1b	0.032	Mouse
vangl2	vang-like 2 (van gogh, Drosophila)	0.032
pnx	posterior neuron-specific homeobox	0.032
gata3	GATA-binding protein 3	0.032
dlx2a	distal-less homeobox gene 2a	0.031
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.031
brd2a	bromodomain-containing 2a	0.031
ndr2	nodal-related 2	0.030
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.030
sox9b	SRY-box containing gene 9b	0.030
notch3	notch homolog 3	0.030
barx1	BarH-like homeobox 1	0.029
ptch1	patched 1	0.029
chd	chordin	0.029
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.029
aplnrb	apelin receptor b	0.029
lef1	lymphocyte enhancer binding factor 1	0.029
prdm14	PR domain containing 14	0.028
rasl11b	RAS-like, family 11, member B	0.028
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.027
fgf10a	fibroblast growth factor 10a	0.027
zbtb4	zinc finger and BTB domain containing 4	0.027
ihha	Indian hedgehog homolog a	0.027	Mouse
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.026
jag1b	jagged 1b	0.026
csnk1a1	casein kinase 1, alpha 1	0.026
ltk	leukocyte tyrosine kinase	0.026
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.025
si:ch211-173b8.2	si:ch211-173b8.2	0.025
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.025
kdrl	kinase insert domain receptor like	0.025
gdnf	glial cell derived neurotrophic factor	0.025
zgc:55813	zgc:55813	0.025
grhl2b	grainyhead-like 2b (Drosophila)	0.025
mical3	flavoprotein oxidoreductase MICAL3	0.025
lrrc50	leucine rich repeat containing 50	0.024
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.024
fn1	fibronectin 1	0.024
pitx3	paired-like homeodomain transcription factor 3	0.024
btg1	B-cell translocation gene 1	0.023
bmper	BMP binding endothelial regulator	0.023
prickle1a	prickle-like 1 (Drosophila) a	0.023
zgc:110298	zgc:110298	0.022
pik3ip1	phosphoinositide-3-kinase interacting protein 1	0.021
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.021
fzd7b	frizzled homolog 7b	0.021
zgc:112329	zgc:112329	0.021
lepr	leptin receptor	0.021
nrp1a	neuropilin 1a	0.021
foxj1a	forkhead box J1a	0.020
smad1	MAD homolog 1 (Drosophila)	0.020
myhc4	myosin heavy chain 4	0.020
hhip	hedgehog interacting protein	0.020
gfra1b	gdnf family receptor alpha 1b	0.020
six4a	sine oculis homeobox homolog 4a	0.020
fgf8a	fibroblast growth factor 8 a	0.020
arx	aristaless related homeobox	0.020
sulf1	sulfatase 1	0.019
six4b	sine oculis homeobox homolog 4b	0.019
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.019
plk3	polo-like kinase 3 (Drosophila)	0.019
LOC564872	monocarboxylate transporter 7-like	0.019
tshz1	teashirt family zinc finger 1	0.019
satb2	SATB homeobox 2	0.019
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.019
bop1	block of proliferation 1	0.019
nkx2.3	NK2 transcription factor related 3	0.019
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.019
entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.018
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.018
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.018
fstl1a	follistatin-like 1a	0.018
zeb1	zinc finger E-box binding homeobox 1	0.018
fgf24	fibroblast growth factor 24	0.018
b3gnt7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	0.017
pcdh18b	protocadherin 18b	0.017
abca5	ATP-binding cassette, sub-family A (ABC1), member 5	0.017
runx2b	runt-related transcription factor 2b	0.017
cnppd1	cyclin Pas1/PHO80 domain containing 1	0.017
appa	amyloid beta (A4) precursor protein a	0.017
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.017
sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.017
vgll4l	vestigial like 4 like	0.017
rx3	retinal homeobox gene 3	0.016
szl	sizzled	0.016
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.016
shhb	sonic hedgehog b	0.016	Mouse
gsc	goosecoid	0.016
zgc:101724	zgc:101724	0.016
col27a1b	collagen, type XXVII, alpha 1b	0.016
rorcb	RAR-related orphan receptor C b	0.016
sox17	SRY-box containing gene 17	0.016
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.016
mef2cb	myocyte enhancer factor 2cb	0.016
olig4	oligodendrocyte transcription factor 4	0.016
tob1a	transducer of ERBB2, 1a	0.016
ifnphi1	interferon phi 1	0.015
tmem2	transmembrane protein 2	0.015
robo2	roundabout homolog 2	0.015
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.015
zgc:55307	zgc:55307	0.015
mid1ip1a	MID1 interacting protein 1a	0.015
cdx4	caudal type homeo box transcription factor 4	0.015
fsta	follistatin a	0.015
uox	urate oxidase	0.015
nr5a5	nuclear receptor subfamily 5, group A, member 5	0.015
trim33	tripartite motif-containing 33	0.015
sqstm1	sequestosome 1	0.015
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.015
copeb	core promoter element binding protein	0.015
gnb1b	guanine nucleotide binding protein (G protein), beta polypeptide 1b	0.015
pdca	phosducin a	0.015
osr2	odd-skipped related 2 (Drosophila)	0.015
sox32	SRY-box containing gene 32	0.015
tsc2	tuberous sclerosis 2	0.014
grn2	granulin 2	0.014
egr1	early growth response 1	0.014
nog1	noggin 1	0.014
foxf1	forkhead box F1	0.014
ptgs1	prostaglandin-endoperoxide synthase 1	0.014
rasgef1ba	RasGEF domain family, member 1Ba	0.014
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.014
aplp2	amyloid beta (A4) precursor-like protein 2	0.014
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.014
itgav	integrin, alpha V	0.014
fign	fidgetin	0.014
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.014
mesp2	mesoderm posterior 2 homolog (mouse)	0.014
epha4a	eph receptor A4a	0.014
klf2a	Kruppel-like factor 2a	0.014
tob1b	transducer of ERBB2, 1b	0.014
foxo3a	forkhead box O3A	0.013
pdlim7	PDZ and LIM domain 7	0.013
slc34a2a	solute carrier family 34 (sodium phosphate), member 2a	0.013
skia	nuclear oncoprotein skia	0.013
LOC100332039	ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like	0.013
slc26a5	solute carrier family 26, member 5	0.013
csrnp1a	cysteine-serine-rich nuclear protein 1a	0.013
arrdc2	arrestin domain containing 2	0.013
id:ibd5051	id:ibd5051	0.013
fabp6	fatty acid binding protein 6, ileal (gastrotropin)	0.013
zgc:112355	zgc:112355	0.013
gle1	GLE1 RNA export mediator homolog (yeast)	0.013
hand2	heart and neural crest derivatives expressed transcript 2	0.013
plxnb2a	plexin b2a	0.013
serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.013
tsc1a	tuberous sclerosis 1a	0.013
boc	brother of CDO	0.013
ext2	exostoses (multiple) 2	0.013
mylipa	myosin regulatory light chain interacting protein a	0.013
pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.013
mych	myelocytomatosis oncogene homolog	0.013
tp73	tumor protein p73	0.013
foxa1	forkhead box A1	0.013
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.012
epha2	eph receptor A2	0.012
oprm1	opioid receptor, mu 1	0.012
pho	phoenix	0.012
eif2ak3	eukaryotic translation initiation factor 2-alpha kinase 3	0.012
bmp16	bone morphogenetic protein 16	0.012
calm1a	calmodulin 1a	0.012
mtp	microsomal triglyceride transfer protein	0.012
bdnf	brain-derived neurotrophic factor	0.012
midn	midnolin	0.012
cry1b	cryptochrome 1b	0.012
tfe3b	transcription factor binding to IGHM enhancer 3b	0.012
zgc:153921	zgc:153921	0.012
zgc:158603	zgc:158603	0.012
LOC572344	hypothetical protein LOC572344	0.012
plagl2	pleiomorphic adenoma gene-like 2	0.012
chrna6	cholinergic receptor, nicotinic, alpha 6	0.012
zgc:73347	zgc:73347	0.012
dlx6a	distal-less homeobox gene 6a	0.012
mical2b	microtubule associated monoxygenase, calponin and LIM domain containing 2b	0.012
fgf3	fibroblast growth factor 3	0.012
angpt1	angiopoietin 1	0.012
ocrl	oculocerebrorenal syndrome of Lowe	0.012
si:ch211-284e13.2	si:ch211-284e13.2	0.012
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.012
irx1b	iroquois homeobox protein 1, b	0.012
atp1b3b	ATPase, Na+/K+ transporting, beta 3b polypeptide	0.012
wtap	Wilms tumor 1 associated protein	0.012
zgc:136773	zgc:136773	0.012
mef2ca	myocyte enhancer factor 2ca	0.012
sgk1	serum/glucocorticoid regulated kinase 1	0.012
fabp1a	fatty acid binding protein 1a, liver	0.012
lhx6	LIM homeobox 6	0.012
gtpbp1	GTP binding protein 1	0.012
pik3r3	phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)	0.012
etv5a	ets variant 5a	0.012
hdac4	histone deacetylase 4	0.012
wnt9a	wingless-type MMTV integration site family, member 9A	0.012
brd2b	bromodomain containing 2b	0.012
igf2a	insulin-like growth factor 2a	0.012
foxd5	forkhead box D5	0.012
slit3	slit (Drosophila) homolog 3	0.011
ef1a	elongation factor 1-alpha	0.011
im:7137555	im:7137555	0.011
hsd17b12a	hydroxysteroid (17-beta) dehydrogenase 12a	0.011
spns2	spinster homolog 2 (Drosophila)	0.011
si:dkey-97i18.2	si:dkey-97i18.2	0.011
mxi1	max interacting protein	0.011
cyp51	cytochrome P450, family 51	0.011
edn1	endothelin 1	0.011
kctd12.1	potassium channel tetramerisation domain containing 12.1	0.011
nrxn2a	neurexin 2a	0.011
notch1a	notch homolog 1a	0.011
mycl1b	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b	0.011
zgc:136878	zgc:136878	0.011
pc	pyruvate carboxylase	0.011
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.011
pax6b	paired box gene 6b	0.011
zfp36l1a	zinc finger protein 36, C3H type-like 1a	0.011
arih1l	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like	0.011
zgc:152984	zgc:152984	0.011
tcf7l1b	transcription factor 7-like 1b (T-cell specific, HMG-box)	0.011
skiv2l2	superkiller viralicidic activity 2-like 2	0.011
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.011
ppp3cb	protein phosphatase 3, catalytic subunit, beta isozyme	0.011
mepce	methylphosphate capping enzyme	0.011
mmp15b	matrix metallopeptidase 15b	0.011
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.011
slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.011
hmgb3a	high-mobility group box 3a	0.011
rnf103	ring finger protein 103	0.011
im:7139293	im:7139293	0.011
bnip3lb	BCL2/adenovirus E1B interacting protein 3-like b	0.011
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.011
frzb	frizzled-related protein	0.011
grnb	granulin b	0.011
pitx2	paired-like homeodomain transcription factor 2	0.011
robo3	roundabout homolog 3	0.011
stk38l	serine/threonine kinase 38 like	0.011
si:ch211-170d8.2	si:ch211-170d8.2	0.011
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.011
kdm5ba	lysine (K)-specific demethylase 5Ba	0.011
ankrd12	ankyrin repeat domain 12	0.011
ids	iduronate 2-sulfatase	0.011
s100a10a	S100 calcium binding protein A10a	0.011
ryr1b	ryanodine receptor 1b (skeletal)	0.011
zgc:163008	zgc:163008	0.011
hoxa13a	homeo box A13a	0.011
zgc:91870	zgc:91870	0.011
drd3	dopamine receptor D3	0.010
dmd	dystrophin	0.010
spon2a	spondin 2a, extracellular matrix protein	0.010
pkd2	polycystic kidney disease 2	0.010	Human
zgc:112421	zgc:112421	0.010
flrt1b	fibronectin leucine rich transmembrane 1b	0.010
axin1	axin 1	0.010
alcamb	activated leukocyte cell adhesion molecule b	0.010
ptpra	protein tyrosine phosphatase, receptor type, A	0.010
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.010
dusp4	dual specificity phosphatase 4	0.010
gna13b	guanine nucleotide binding protein (G protein), alpha 13b	0.010
upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.010
si:dkey-177e13.4	si:dkey-177e13.4	0.010
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.010
aktip	akt interacting protein	0.010
wnt3a	wingless-type MMTV integration site family, member 3A	0.010
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.010
tmem198b	transmembrane protein 198b	0.010
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.010
si:dkey-233h2.3	si:dkey-233h2.3	0.010
cart1	cartilage paired-class homeoprotein 1	0.010
lama5	laminin, alpha 5	0.010
smad3a	MAD homolog 3a (Drosophila)	0.010
klf4a	Kruppel-like transcription factor 4a	0.010
hoxc1a	homeo box C1a	0.010
arl4ab	ADP-ribosylation factor-like 4ab	0.010
cnn2	calponin 2	0.010
zgc:73225	zgc:73225	0.010
pfkfb4l	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, like	0.010
hif1al	hypoxia-inducible factor 1, alpha subunit, like	0.010
eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.010
npdc1	neural proliferation, differentiation and control, 1	0.010
dlg2	discs, large (Drosophila) homolog 2	0.010
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.010
rc3	rabconnectin 3	0.010
ctgf	connective tissue growth factor	0.010
si:ch211-285f17.1	si:ch211-285f17.1	0.010
smo	smoothened homolog (Drosophila)	0.010