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Danio rerio

26 genes annotated in zebrafish

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regulation of angiogenesis

GO:0045765

Any process that modulates the frequency, rate or extent of angiogenesis.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of angiogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of angiogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
plcg1	phospholipase C, gamma 1	0.641	Human
kdrl	kinase insert domain receptor like	0.602
notch3	notch homolog 3	0.546
fbn2b	fibrillin 2b	0.428
dll4	delta-like 4 (Drosophila)	0.337
efnb2a	ephrin B2a	0.263
cdh5	cadherin 5	0.257
nrarpa	notch-regulated ankyrin repeat protein a	0.239
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.178	Human Mouse
fn1	fibronectin 1	0.176
nrp1a	neuropilin 1a	0.153
foxn4	forkhead box N4	0.136
ephb4a	eph receptor B4a	0.121
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.121
ccm2	cerebral cavernous malformation 2	0.118
vegfc	vascular endothelial growth factor c	0.117
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.097
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.095
sulf1	sulfatase 1	0.092	Human
tie2	endothelium-specific receptor tyrosine kinase 2	0.089	Human Mouse Rat
agtr2	angiotensin II receptor, type 2	0.086
dlc	deltaC	0.084	Zebrafish
etv2	ets variant gene 2	0.082
dla	deltaA	0.082	Zebrafish
plxnd1	plexin D1	0.078
ilk	integrin linked kinase	0.077
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.069	Human
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.067
krit1	KRIT1, ankyrin repeat containing	0.067	Human Mouse
jag2	jagged 2	0.063	Zebrafish
ptgs1	prostaglandin-endoperoxide synthase 1	0.062
col5a2l	collagen, type V, alpha 2-like	0.062
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.061
lama5	laminin, alpha 5	0.058
dnd	dead end	0.056
epas1b	endothelial PAS domain protein 1b	0.053
hoxb5b	homeo box B5b	0.052
dlb	deltaB	0.050	Zebrafish
calcrla	calcitonin receptor-like a	0.048
antxr1	anthrax toxin receptor 1	0.047
irx3a	iroquois homeobox protein 3a	0.047
tal1	T-cell acute lymphocytic leukemia 1	0.047
mcamb	melanoma cell adhesion molecule b	0.047
wnt11r	wingless-type MMTV integration site family, member 11, related	0.045
vegfaa	vascular endothelial growth factor Aa	0.045
si:ch73-60e21.1	si:ch73-60e21.1	0.045
sox9a	SRY-box containing gene 9a	0.045
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.044
tcf12	transcription factor 12	0.044
nf1a	neurofibromin 1a	0.044	Mouse
fsta	follistatin a	0.043
sulf2	sulfatase 2	0.043
selp	selectin P	0.041
bmp2b	bone morphogenetic protein 2b	0.041
pdgfrb2	platelet derived growth factor receptor beta 2	0.040
neurod4	neurogenic differentiation 4	0.040
edn1	endothelin 1	0.040
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.039
col2a1a	collagen type II, alpha-1a	0.038
traf4a	tnf receptor-associated factor 4a	0.038
gli2a	GLI-Kruppel family member GLI2a	0.038
hspa12b	heat shock protein 12B	0.037
olig2	oligodendrocyte lineage transcription factor 2	0.036
nrp1b	neuropilin 1b	0.036	Zebrafish
ankrd6	ankyrin repeat domain 6	0.035
prdm16	PR domain containing 16	0.035
pitx3	paired-like homeodomain transcription factor 3	0.035
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.035
sb:cb560	sb:cb560	0.035
thbs1	thrombospondin 1	0.034	Human Mouse
pcdh18b	protocadherin 18b	0.034
tbx20	T-box 20	0.033
fras1	Fraser syndrome 1	0.033
si:ch211-212m21.5	si:ch211-212m21.5	0.033
dlg2	discs, large (Drosophila) homolog 2	0.032
nrp2a	neuropilin 2a	0.032	Zebrafish
hlxb9la	homeo box HB9 like a	0.032
dld	deltaD	0.032	Zebrafish
atoh8	atonal homolog 8	0.031
flt4	fms-related tyrosine kinase 4	0.031
olig4	oligodendrocyte transcription factor 4	0.031
hhex	hematopoietically expressed homeobox	0.031
arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.031
acvrl1	activin A receptor type II-like 1	0.031	Mouse
pax8	paired box gene 8	0.030
LOC796298	isotocin receptor-like 1	0.030
LOC100003514	protein kinase C alpha type-like	0.030
twist1a	twist1a	0.029
tie1	endothelium-specific receptor tyrosine kinase 1	0.029	Mouse
cds2	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.028
gja3	gap junction protein, alpha 3	0.028
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.028
wt1b	wilms tumor 1b	0.028
igf1ra	insulin-like growth factor 1a receptor	0.028
ntn2	netrin 2	0.028
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.028
wt1a	wilms tumor 1a	0.027
bty	bloodthirsty	0.027
eng1a	engrailed 1a	0.027
hoxb4a	homeo box B4a	0.027
tagln	transgelin	0.026
odc1	ornithine decarboxylase 1	0.026
unc5b	unc-5 homolog B (C. elegans)	0.026
prox1b	prospero-related homeobox gene 1b	0.026
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.026
dcc	deleted in colorectal carcinoma	0.026
neurog1	neurogenin 1	0.025
hoxb2a	homeo box B2a	0.025
ntn4	netrin 4	0.024
tagln2	transgelin 2	0.024
tpm4	tropomyosin 4	0.024
nf1b	neurofibromin 1b	0.024	Mouse
postn	periostin, osteoblast specific factor	0.024
wu:fv91b12	wu:fv91b12	0.024
angpt1	angiopoietin 1	0.023
fzd7a	frizzled homolog 7a	0.023
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.023
col12a1	collagen, type XII, alpha 1	0.023
sars	seryl-tRNA synthetase	0.023
boc	brother of CDO	0.022
krt8	keratin 8	0.022
otpb	orthopedia homolog b	0.022
acvr1l	activin A receptor, type I like	0.022
pax9	paired box gene 9	0.021
cyp1b1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.021	Mouse
mib	mind bomb	0.021
rock2b	rho-associated, coiled-coil containing protein kinase 2b	0.021	Human
esama	endothelial cell adhesion molecule a	0.021
tp63	tumor protein p63	0.021	Zebrafish
notch1b	notch homolog 1b	0.021	Human
zgc:153148	zgc:153148	0.021
dusp5	dual specificity phosphatase 5	0.021
rbp4	retinol binding protein 4, plasma	0.020
hoxa1a	homeo box A1a	0.020
lypd6	LY6/PLAUR domain containing 6	0.020
ptprf	protein tyrosine phosphatase, receptor type, F	0.020
guca1c	guanylate cyclase activator 1C	0.020
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.020
wtip	Wilms tumor 1 interacting protein	0.020
sema3ab	semaphorin 3ab	0.020
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.019
wnt10a	wingless-type MMTV integration site family, member 10a	0.019
cpb1	carboxypeptidase B1 (tissue)	0.019
ptch2	patched 2	0.019
itga5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.019
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.019
trpv4	transient receptor potential cation channel, subfamily V, member 4	0.019
loxl2b	lysyl oxidase-like 2b	0.019
prnprs1	prion protein, related sequence 1	0.019
si:ch211-235f6.2	si:ch211-235f6.2	0.019
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.019
ren	renin	0.019
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.019
zbtb4	zinc finger and BTB domain containing 4	0.019
gata2a	GATA-binding protein 2a	0.018	Human Mouse
sox19a	SRY-box containing gene 19a	0.018
sox2	SRY-box containing gene 2	0.018
igf2b	insulin-like growth factor 2b	0.018
alcamb	activated leukocyte cell adhesion molecule b	0.018
elk4	ELK4, ETS-domain protein	0.018
s1pr1	sphingosine-1-phosphate receptor 1	0.018
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.017
zgc:85866	zgc:85866	0.017
gdf6b	growth differentiation factor 6b	0.017
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.017
ryr3	ryanodine receptor 3	0.017
egr1	early growth response 1	0.017
sox7	SRY-box containing gene 7	0.017
dzip1	DAZ interacting protein 1	0.017
vasp	vasodilator-stimulated phosphoprotein	0.017
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.017
dag1	dystroglycan 1	0.017
dbx1b	developing brain homeobox 1b	0.017
pdzrn3	PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3	0.017
osr2	odd-skipped related 2 (Drosophila)	0.017
jun	jun proto-oncogene	0.017
tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.017
pax2a	paired box gene 2a	0.017
mrc1a	mannose receptor, C type 1a	0.016
ptprk	protein tyrosine phosphatase, receptor type, K	0.016
onecutl	one cut domain, family member, like	0.016
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.016
mapk6	mitogen-activated protein kinase 6	0.016
hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.016
phf21a	PHD finger protein 21A	0.016
lepre1	Lepre1 protein	0.016
hoxb5a	homeo box B5a	0.016
dab2	disabled homolog 2 (Drosophila)	0.016
foxc1b	forkhead box C1b	0.016
si:ch211-14k19.8	si:ch211-14k19.8	0.016
alcama	activated leukocyte cell adhesion molecule a	0.016
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.016
calm3b	calmodulin 3b (phosphorylase kinase, delta)	0.015
pou3f2	POU class 3 homeobox 2	0.015
zgc:112180	zgc:112180	0.015
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.015
tjp2b	tight junction protein 2b (zona occludens 2)	0.015
birc2	baculoviral IAP repeat-containing 2	0.015	Zebrafish
wnt4a	wingless-type MMTV integration site family, member 4a	0.015
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.015
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.015
cyp1d1	cytochrome P450, family 1, subfamily D, polypeptide 1	0.015
mtp	microsomal triglyceride transfer protein	0.015
pdgfrl	platelet-derived growth factor receptor-like	0.015
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.015
rfng	radical fringe homolog (Drosophila)	0.015
sb:cb62	sb:cb62	0.015
gpx7	glutathione peroxidase 7	0.015
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.015
prkcq	protein kinase C, theta	0.015	Zebrafish
aox3	aldehyde oxidase 3	0.015
plxna3	plexin A3	0.015
aplnrb	apelin receptor b	0.015
ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.015
hoxd3a	homeo box D3a	0.015
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.015
frem2a	Fras1 related extracellular matrix protein 2a	0.014
jag1b	jagged 1b	0.014	Zebrafish
gli1	GLI-Kruppel family member 1	0.014
mespb	mesoderm posterior b	0.014
bhlhe41	basic helix-loop-helix family, member e41	0.014
ecscr	endothelial cell-specific chemotaxis regulator	0.014
meis2.2	myeloid ecotropic viral integration site 2.2	0.014
rictor	RPTOR independent companion of MTOR, complex 2	0.014
ptprja	protein tyrosine phosphatase, receptor type, J a	0.014
dbx1a	developing brain homeobox 1a	0.014
ednra	endothelin receptor type A	0.014
fes	feline sarcoma oncogene	0.014
plekhg5a	pleckstrin homology domain containing, family G (with RhoGef domain) member 5a	0.014
ifnphi1	interferon phi 1	0.014
glceb	glucuronyl C5-epimerase b	0.014
ptrfb	polymerase I and transcript release factor b	0.014
fgfr3	fibroblast growth factor receptor 3	0.014
ca10a	carbonic anhydrase Xa	0.014
jup	junction plakoglobin	0.014
ass1	argininosuccinate synthetase 1	0.014
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.014
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.014
hoxd4a	homeo box D4a	0.014
enpep	glutamyl aminopeptidase	0.014
LOC798872	deiodinase 3	0.014
nr1h3	nuclear receptor subfamily 1, group H, member 3	0.014
hoxc9a	homeo box C9a	0.014
crb2b	crumbs homolog 2b	0.014
ccbe1	collagen and calcium binding EGF domains 1	0.013	Mouse
gpc4	glypican 4	0.013
lama1	laminin, alpha 1	0.013
atoh7	atonal homolog 7	0.013
fzd5	frizzled homolog 5	0.013
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.013
col9a3	collagen, type IX, alpha 3	0.013
notch2	notch homolog 2	0.013
zgc:103482	zgc:103482	0.013
utrn	utrophin	0.013
igfbp7	insulin-like growth factor binding protein 7	0.013
cyr61l1	cysteine-rich, angiogenic inducer 61 like 1	0.013
sema3fa	semaphorin 3fa	0.013
matn4	matrilin 4	0.013
sulf2l	sulfatase 2, like	0.013
metrn	meteorin, glial cell differentiation regulator	0.013
fgfrl1b	fibroblast growth factor receptor-like 1b	0.013
skia	nuclear oncoprotein skia	0.013
ptk2.1	protein tyrosine kinase 2a	0.013
tjp2a	tight junction protein 2a (zona occludens 2)	0.013
myl10	myosin, light chain 10, regulatory	0.013
col7a1l	collagen type VII alpha 1-like	0.013
si:dkeyp-68f6.1	si:dkeyp-68f6.1	0.013
il8	interleukin 8	0.013
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.013
tnnt2a	troponin T2a, cardiac	0.013
cdx1a	caudal type homeo box transcription factor 1 a	0.012
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.012
zgc:92806	zgc:92806	0.012
epb41l5	erythrocyte membrane protein band 4.1 like 5	0.012
srpx	sushi-repeat-containing protein	0.012
ier5l	immediate early response 5-like	0.012
pdcd2	programmed cell death 2	0.012
gb:bm036580	gb:bm036580	0.012
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.012
itgav	integrin, alpha V	0.012
sema3h	semaphorin 3h	0.012
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.012
cct5	chaperonin containing TCP1, subunit 5 (epsilon)	0.012
igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.012
pgm1	phosphoglucomutase 1	0.012
hsp47	heat shock protein 47	0.012
coe2	coe2	0.012
gata1a	GATA binding protein 1a	0.012
xirp2b	xin actin-binding repeat containing 2b	0.012
plag1	pleiomorphic adenoma gene 1	0.012
lamb1a	laminin, beta 1a	0.012
eng2a	engrailed 2a	0.012
opn4x1	opsin 4x1	0.012
zgc:110340	zgc:110340	0.012
naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.012
klf2a	Kruppel-like factor 2a	0.012
pax7b	paired box gene 7b	0.012
itk	IL2-inducible T-cell kinase	0.012
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.012
pitx1	paired-like homeodomain transcription factor 1	0.012
esr1	estrogen receptor 1	0.012
pdgfaa	platelet-derived growth factor alpha a	0.012
pld1a	phospholipase D1a	0.012
vgll4l	vestigial like 4 like	0.012
epb4.1l4	erythrocyte protein band 4.1-like 4	0.012
nadka	NAD kinase a	0.012
he2	hatching enzyme 2	0.012
tbx1	T-box 1	0.012
si:dkey-202c5.1	si:dkey-202c5.1	0.012
fzd6	frizzled homolog 6 (Drosophila)	0.012
rxrbb	retinoid x receptor, beta b	0.012
isl2a	islet2a	0.011
pdlim2	PDZ and LIM domain 2 (mystique)	0.011
ptprjb	protein tyrosine phosphatase, receptor type, J b	0.011
entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
kop	askopos	0.011
f7	coagulation factor VII	0.011
zic6	zic family member 6	0.011
kirrela	kin of IRRE like a	0.011
zgc:56116	zgc:56116	0.011
cpa1	carboxypeptidase A1 (pancreatic)	0.011
aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.011
naa50	N(alpha)-acetyltransferase 50, NatE catalytic subunit	0.011
nkx2.2b	NK2 transcription factor related 2b	0.011
rx3	retinal homeobox gene 3	0.011
plekhg4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	0.011
cldni	claudin i	0.011
dcn	decorin	0.011
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.011
irgq1	immunity-related GTPase family, q1	0.011
cnn2	calponin 2	0.011
gulp1	GULP, engulfment adaptor PTB domain containing 1	0.011
zgc:112161	zgc:112161	0.011
tp53inp1	tumor protein p53 inducible nuclear protein 1	0.011
six2a	sine oculis-related homeobox 2a	0.011
hand2	heart and neural crest derivatives expressed transcript 2	0.011
arhgap29a	Rho GTPase activating protein 29a	0.011
vasn	vasorin	0.011
csnk1da	casein kinase 1, delta a	0.011
zgc:111821	zgc:111821	0.011
plk3	polo-like kinase 3 (Drosophila)	0.011
wnt5b	wingless-type MMTV integration site family, member 5b	0.011	Human
tdrd7	tudor domain containing 7	0.011
dscam	Down syndrome cell adhesion molecule	0.011
fgfr4	fibroblast growth factor receptor 4	0.011
hs3st1l1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like1	0.011
cxcl12a	chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)	0.011
mmp2	matrix metalloproteinase 2	0.011
zgc:112211	zgc:112211	0.011
pmp22a	peripheral myelin protein 22a	0.011
myo6a	myosin VIa	0.011
prkcbb	protein kinase C, beta b	0.011	Zebrafish
cyp1a	cytochrome P450, family 1, subfamily A	0.011
hsp90a.2	heat shock protein 90-alpha 2	0.011
acsl4l	acyl-CoA synthetase long-chain family member 4, like	0.011
hapln3	hyaluronan and proteoglycan link protein 3	0.011
cldn15la	claudin 15-like a	0.011
ptpra	protein tyrosine phosphatase, receptor type, A	0.011
jazf1b	JAZF zinc finger 1b	0.011
prl	prolactin	0.011
csrp3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.011
lrrc6	leucine rich repeat containing 6	0.011
wu:fb76c12	wu:fb76c12	0.011
slc2a1a	solute carrier family 2 (facilitated glucose transporter), member 1a	0.011
hmga1a	high mobility group AT-hook 1a	0.010
mapk1	mitogen-activated protein kinase 1	0.010
vhl	von Hippel-Lindau tumor suppressor	0.010
tgm2	transglutaminase 2, C polypeptide	0.010
acy3.2	aspartoacylase (aminocyclase) 3.2	0.010
her4.5	hairy-related 4.5	0.010
prrx1a	paired related homeobox 1a	0.010
cldn15a	claudin 15a	0.010
egr2a	early growth response 2a	0.010
rx1	retinal homeobox gene 1	0.010
gli3	GLI-Kruppel family member GLI3	0.010
ppp1r14bb	protein phosphatase 1, regulatory (inhibitor) subunit 14Bb	0.010
fgf19	fibroblast growth factor 19	0.010
fermt2	fermitin family homolog 2 (Drosophila)	0.010
perp	PERP, TP53 apoptosis effector	0.010
ihhb	Indian hedgehog homolog b	0.010
lmo2	LIM domain only 2 (rhombotin-like 1)	0.010
cpa2	carboxypeptidase A2 (pancreatic)	0.010
pth1a	parathyroid hormone 1a	0.010
wnt10b	wingless-type MMTV integration site family, member 10b	0.010
zgc:112079	zgc:112079	0.010
lhfpl2	lipoma HMGIC fusion partner-like 2	0.010
hoxc1a	homeo box C1a	0.010
frem3	Fras1 related extracellular matrix 3	0.010
gipc1	GIPC PDZ domain containing family, member 1	0.010
sb:eu512	sb:eu512	0.010
flnbl	filamin B, like	0.010
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.010
zgc:163064	zgc:163064	0.010