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Process View

Danio rerio

12 genes annotated in zebrafish

ventricular system development

The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventricular system development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventricular system development" (in gray)

Name	Description	Probability	Func Analog Organism
wnt10a	wingless-type MMTV integration site family, member 10a	0.800	Zebrafish
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.779
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.612	Zebrafish
wnt1	wingless-type MMTV integration site family, member 1	0.564
sox1a	SRY-box containing gene 1a	0.537
dbx1a	developing brain homeobox 1a	0.478
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.451	Zebrafish
wnt4a	wingless-type MMTV integration site family, member 4a	0.439	Zebrafish
lhx5	LIM homeobox 5	0.437	Zebrafish
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.421	Zebrafish
hnf1ba	HNF1 homeobox Ba	0.378
wnt3a	wingless-type MMTV integration site family, member 3A	0.356	Zebrafish
wnt8b	wingless-type MMTV integration site family, member 8b	0.349	Zebrafish
barhl2	BarH-like 2	0.345
zic4	zic family member 4	0.343
fgf3	fibroblast growth factor 3	0.338
dld	deltaD	0.286
lef1	lymphocyte enhancer binding factor 1	0.285
znf503	zinc finger protein 503	0.278
irx5a	iroquois homeobox protein 5a	0.275
dla	deltaA	0.261
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.260
hoxb5b	homeo box B5b	0.255
gbx1	gastrulation brain homeobox 1	0.237
hoxb2a	homeo box B2a	0.231	Zebrafish
hoxa3a	homeo box A3a	0.205
wnt2	wingless-type MMTV integration site family member 2	0.205	Zebrafish
hoxc4a	homeo box C4a	0.193
sox3	SRY-box containing gene 3	0.184
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.182
zic5	zic family member 5 (odd-paired homolog, Drosophila)	0.175	Zebrafish
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.175
map2k4a	mitogen-activated protein kinase kinase 4a	0.170
fzd10	frizzled homolog 10	0.169
hoxd4a	homeo box D4a	0.159
dlb	deltaB	0.156
lhx1a	LIM homeobox 1a	0.154	Zebrafish
hoxa2b	homeo box A2b	0.154	Zebrafish
rest	RE1-silencing transcription factor	0.148
tpbgl	trophoblast glycoprotein-like	0.144
gpr126	G protein-coupled receptor 126	0.142
wnt11	wingless-type MMTV integration site family, member 11	0.138	Zebrafish
sox19a	SRY-box containing gene 19a	0.138
etv5b	ets variant 5b	0.121
hmx4	H6 family homeobox 4	0.119
lmo3	LIM domain only 3	0.118
epb4.1l4	erythrocyte protein band 4.1-like 4	0.115
twist3	twist3	0.103
zbtb4	zinc finger and BTB domain containing 4	0.102
smad9	MAD homolog 9 (Drosophila)	0.096
fgf10a	fibroblast growth factor 10a	0.094
axin2	axin 2 (conductin, axil)	0.090
irx3a	iroquois homeobox protein 3a	0.086
hoxb3a	homeo box B3a	0.085
sim2	single-minded homolog 2 (Drosophila)	0.085
otpb	orthopedia homolog b	0.084
lfng	lunatic fringe homolog	0.082	Zebrafish
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.082
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.082
epha4b	eph receptor A4b	0.081
itgav	integrin, alpha V	0.076
hoxa4a	homeo box A4a	0.076
vsx1	visual system homeobox 1 homolog, chx10-like	0.074
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.072
ndr2	nodal-related 2	0.068
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.067
neurod4	neurogenic differentiation 4	0.065
olig3	oligodendrocyte transcription factor 3	0.065
shhb	sonic hedgehog b	0.065
foxa2	forkhead box A2	0.061
pax6a	paired box gene 6a	0.059
fezf2	FEZ family zinc finger 2	0.059
mab21l2	mab-21-like 2	0.058
neurog1	neurogenin 1	0.056
meis2.1	myeloid ecotropic viral integration site 2.1	0.056
map2k4b	mitogen-activated protein kinase kinase 4b	0.055
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.055	Zebrafish
her15.1	hairy and enhancer of split-related 15.1	0.054
hoxa5a	homeo box A5a	0.054
dlx2b	distal-less homeobox gene 2b	0.053
wnt16	wingless-type MMTV integration site family, member 16	0.053
gbx2	gastrulation brain homeo box 2	0.053
clic4	chloride intracellular channel 4	0.051
twist1b	twist1b	0.051
otx1b	orthodenticle homolog 1b	0.051
foxb1.2	forkhead box B1.2	0.051
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.050
fgf17	fibroblast growth factor 17	0.050
pax6b	paired box gene 6b	0.050
cdh6	cadherin 6	0.049
mecom	MDS1 and EVI1 complex locus	0.048
sb:cb81	sb:cb81	0.047
dkk1b	dickkopf 1b	0.046
lhx2b	LIM homeobox 2b	0.045	Zebrafish
onecutl	one cut domain, family member, like	0.045
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.045	Zebrafish
pcdh18a	protocadherin 18a	0.045
wnt10b	wingless-type MMTV integration site family, member 10b	0.044	Zebrafish
olig4	oligodendrocyte transcription factor 4	0.044
sox2	SRY-box containing gene 2	0.044
atp1a3a	ATPase, Na+/K+ transporting, alpha 3a polypeptide	0.044
shha	sonic hedgehog a	0.042
six2a	sine oculis-related homeobox 2a	0.041
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.041
her3	hairy-related 3	0.041
pax8	paired box gene 8	0.040
tnnt2a	troponin T2a, cardiac	0.040
edn1	endothelin 1	0.039
gata3	GATA-binding protein 3	0.039
kitb	kit receptor b	0.039
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.039
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.038	Zebrafish
wnt11r	wingless-type MMTV integration site family, member 11, related	0.038	Zebrafish
tal1	T-cell acute lymphocytic leukemia 1	0.037
pcdh8	protocadherin 8	0.037
eng2a	engrailed 2a	0.036
lmo4a	LIM domain only 4a	0.035
meis3	myeloid ecotropic viral integration site 3	0.035
hmx3	homeo box (H6 family) 3	0.034
insm1b	insulinoma-associated 1b	0.033
pax2a	paired box gene 2a	0.033
foxp2	forkhead box P2	0.033
si:ch211-173o4.2	si:ch211-173o4.2	0.032
raraa	retinoic acid receptor, alpha a	0.032
gli3	GLI-Kruppel family member GLI3	0.032
zfyve26	zinc finger, FYVE domain containing 26	0.031
oprk1	opioid receptor, kappa 1	0.030
wnt9b	wingless-type MMTV integration site family, member 9B	0.030	Zebrafish
fgfr4	fibroblast growth factor receptor 4	0.030
dlx1a	distal-less homeobox gene 1a	0.029
hlxb9lb	homeo box HB9 like b	0.029
tbx1	T-box 1	0.029
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.028
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.028
irx1b	iroquois homeobox protein 1, b	0.027
aqp8a.1	aquaporin 8a, tandem duplicate 1	0.027
tfap2a	transcription factor AP-2 alpha	0.027
sp5l	Sp5 transcription factor-like	0.026
mapk12	mitogen-activated protein kinase 12	0.026
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.026
hoxb8a	homeo box B8a	0.026
rbp4	retinol binding protein 4, plasma	0.026
dharma	dharma	0.025
fzd7a	frizzled homolog 7a	0.025
hoxb6b	homeo box B6b	0.025
wnt5b	wingless-type MMTV integration site family, member 5b	0.025	Zebrafish
flh	floating head	0.025
wif1	wnt inhibitory factor 1	0.025
nrg2a	neuregulin 2a	0.025
chrna4	cholinergic receptor, nicotinic, alpha 4	0.024
map2k7	mitogen-activated protein kinase kinase 7	0.024
mapk4	mitogen-activated protein kinase 4	0.024
msxb	muscle segment homeobox B	0.024
hoxb10a	homeo box B10a	0.024
six4a	sine oculis homeobox homolog 4a	0.024
nkx1.2la	NK1 transcription factor related 2-like,a	0.024
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.023
rx3	retinal homeobox gene 3	0.023
notum3	notum 3	0.023
six4b	sine oculis homeobox homolog 4b	0.023
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.023
cdx4	caudal type homeo box transcription factor 4	0.023
emx1	empty spiracles homeobox 1	0.023
crabp2a	cellular retinoic acid binding protein 2, a	0.023
ecm2	extracellular matrix protein 2, female organ and adipocyte specific	0.022
nkx3.2	NK3 homeobox 2	0.022
dlx4a	distal-less homeobox gene 4a	0.022
her4.2	hairy-related 4.2	0.022
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.022
anxa4	annexin A4	0.022
dlx2a	distal-less homeobox gene 2a	0.022
dusp6	dual specificity phosphatase 6	0.022
foxg1a	forkhead box G1a	0.021
lhx1b	LIM homeobox 1b	0.021	Zebrafish
eef2l2	eukaryotic translation elongation factor 2, like 2	0.021
itgb3b	integrin beta 3b	0.021
bon	bonnie and clyde	0.021
sipa1l1	signal-induced proliferation-associated 1 like 1	0.021
fgfr2	fibroblast growth factor receptor 2	0.021
nkx2.2a	NK2 transcription factor related 2a	0.021
zic6	zic family member 6	0.021	Zebrafish
veph	ventricular zone expressed PH domain protein	0.021
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.020
gle1	GLE1 RNA export mediator homolog (yeast)	0.020
foxd3	forkhead box D3	0.020
irx7	iroquois homeobox protein 7	0.020
sim1a	single-minded homolog 1a (Drosophila)	0.020
ctgf	connective tissue growth factor	0.019
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.019	Zebrafish
nkd1	naked cuticle homolog 1 (Drosophila)	0.019
foxb1.1	forkhead box B1.1	0.019
ift46	intraflagellar transport protein 46	0.019
eomesa	eomesodermin homolog a	0.018
foxa1	forkhead box A1	0.018
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.018
hoxc8a	homeo box C8a	0.018
olfm2	olfactomedin 2	0.018
gdf6b	growth differentiation factor 6b	0.018
ncam1b	neural cell adhesion molecule 1b	0.018
ephb4b	eph receptor B4b	0.018
lmo1	LIM domain only 1	0.018
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.018
cntfr	ciliary neurotrophic factor receptor	0.018
sox8	SRY-box containing gene 8	0.017
scube2	signal peptide, CUB domain, EGF-like 2	0.017
hmx1	H6 homeo box 1	0.017
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.017
cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.017
gfap	glial fibrillary acidic protein	0.017
bmp2a	bone morphogenetic protein 2a	0.017
atp1a1a.3	ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide	0.017	Zebrafish
pou3f2	POU class 3 homeobox 2	0.017
glceb	glucuronyl C5-epimerase b	0.017
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.017
wnt3	wingless-type MMTV integration site family, member 3	0.017	Zebrafish
amotl2a	angiomotin like 2a	0.016
ppp1r3ca	protein phosphatase 1, regulatory (inhibitor) subunit 3Ca	0.016
bmp4	bone morphogenetic protein 4	0.016
evx1	even-skipped homeobox 1	0.016
gja3	gap junction protein, alpha 3	0.016
sfrp2	secreted frizzled-related protein 2	0.016
olig2	oligodendrocyte lineage transcription factor 2	0.016
hoxb5a	homeo box B5a	0.016
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.015
sp2	sp2 transcription factor	0.015
ext1b	exostoses (multiple) 1b	0.015
robo2	roundabout homolog 2	0.015
six1a	sine oculis homeobox homolog 1a	0.015
coe2	coe2	0.015
fbxl14b	F-box and leucine-rich repeat protein 14b	0.015
wnt4b	wingless-type MMTV integration site family, member 4b	0.015	Zebrafish
nkx2.2b	NK2 transcription factor related 2b	0.015
nkx2.1b	NK2 homeobox 1b	0.015
tal2	T-cell acute lymphocytic leukemia 2	0.015
eng1b	engrailed 1b	0.015
rgs4	regulator of G-protein signalling 4	0.015
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.014
dcc	deleted in colorectal carcinoma	0.014
mapk15	mitogen-activated protein kinase 15	0.014
pax9	paired box gene 9	0.014
cables1	Cdk5 and Abl enzyme substrate 1	0.014
msxc	muscle segment homeobox C	0.014
npy8br	neuropeptide Y receptor Y8b	0.014
dlc	deltaC	0.014
egr2b	early growth response 2b	0.014
tbx2a	T-box gene 2a	0.014
og9x	OG9 homeobox gene	0.014
csad	cysteine sulfinic acid decarboxylase	0.014
glra4a	glycine receptor, alpha 4a	0.014
sfrp1b	secreted frizzled-related protein 1b	0.014
otpa	orthopedia homolog a	0.014
dlx6a	distal-less homeobox gene 6a	0.014
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.013
krt15	keratin 15	0.013
atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.013
zgc:55582	zgc:55582	0.013
spaw	southpaw	0.013
robo1	roundabout homolog 1	0.013
lox	lysyl oxidase	0.013
hoxa9a	homeo box A9a	0.013
epha4a	eph receptor A4a	0.013
fbn2b	fibrillin 2b	0.013
wdr69	WD repeat domain 69	0.013
tmem57a	transmembrane protein 57a	0.013
dopey1	dopey family member 1	0.013
tmem2	transmembrane protein 2	0.012
oprd1b	opioid receptor, delta 1b	0.012
her8a	hairy-related 8a	0.012
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.012
sp5	Sp5 transcription factor	0.012
efna2	ephrin A2	0.012
tmem170a	transmembrane protein 170A	0.012
meis2.2	myeloid ecotropic viral integration site 2.2	0.012
hoxc6a	homeo box C6a	0.012
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.012
ptprb	protein tyrosine phosphatase, receptor type, b	0.012
prickle1b	prickle homolog 1 (Drosophila) b	0.012
angptl2	angiopoietin-like 2	0.012
pou3f3b	POU class 3 homeobox 3b	0.012
pou3f3a	POU class 3 homeobox 3a	0.012
hoxd3a	homeo box D3a	0.012
barhl1.2	BarH-like 1.2	0.012
her9	hairy-related 9	0.012
LOC566708	FL cytokine receptor-like	0.011
mtnr1ba	melatonin receptor type 1B a	0.011
rgma	RGM domain family, member A	0.011
hhip	hedgehog interacting protein	0.011
lhx9	LIM homeobox 9	0.011	Zebrafish
osr2	odd-skipped related 2 (Drosophila)	0.011
bcl2	B-cell leukemia/lymphoma 2	0.011
wnt8a	wingless-type MMTV integration site family, member 8a	0.011	Zebrafish
arg2	arginase, type II	0.011
slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.011
penkb	proenkephalin b	0.011
myf6	myogenic factor 6	0.011
foxj1b	forkhead box J1b	0.011
tlx2	T-cell leukemia, homeobox 2	0.011
ldb2b	LIM-domain binding factor 2b	0.011
eng2b	engrailed 2b	0.011
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.011
nrarpa	notch-regulated ankyrin repeat protein a	0.011
zgc:66326	zgc:66326	0.011
gli2b	GLI-Kruppel family member GLI2b	0.011
siah2l	seven in absentia homolog 2 (Drosophila)-like	0.011
znf711	zinc finger protein 711	0.011
uros	uroporphyrinogen III synthase	0.010
ttc26	tetratricopeptide repeat domain 26	0.010
arid4a	AT rich interactive domain 4A (RBP1-like)	0.010
trim3a	tripartite motif-containing 3a	0.010
shroom4	shroom family member 4	0.010
LOC100534712	hypothetical protein LOC100534712	0.010
gsc	goosecoid	0.010
irx4a	iroquois homeobox protein 4a	0.010
inab	internexin neuronal intermediate filament protein, alpha b	0.010
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.010
ephb3a	eph receptor B3a	0.010
atp1b1a	ATPase, Na+/K+ transporting, beta 1a polypeptide	0.010
hoxb6a	homeo box B6a	0.010