IMP
Process View
The network for 'smooth muscle cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
smooth muscle cell proliferation
The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 1.000 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.997 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.961 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.942 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.921 | |
| EGFR | epidermal growth factor receptor | 0.898 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.891 | |
| JAG1 | jagged 1 | 0.852 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.842 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.834 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.805 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.754 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.709 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.675 | |
| PSEN1 | presenilin 1 | 0.645 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.569 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.480 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.460 | |
| IRS1 | insulin receptor substrate 1 | 0.442 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.428 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.402 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.402 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.393 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.355 | |
| TRAF6 | TNF receptor-associated factor 6 | 0.351 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.346 | |
| JUNB | jun B proto-oncogene | 0.340 | |
| S100B | S100 calcium binding protein B | 0.330 | |
| AR | androgen receptor | 0.328 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.327 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.300 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.289 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.280 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.279 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.269 | |
| VEGFA | vascular endothelial growth factor A | 0.267 | |
| IL8 | interleukin 8 | 0.231 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.223 | |
| DSG2 | desmoglein 2 | 0.216 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.216 | |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.215 | |
| NOSTRIN | nitric oxide synthase trafficker | 0.210 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.197 | |
| RALB | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 0.196 | |
| APC | adenomatous polyposis coli | 0.193 | |
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.192 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.189 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.186 | |
| TBXA2R | thromboxane A2 receptor | 0.185 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.182 | |
| ESR1 | estrogen receptor 1 | 0.153 | |
| RNASE4 | ribonuclease, RNase A family, 4 | 0.147 | |
| TGFB3 | transforming growth factor, beta 3 | 0.142 | |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.138 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.133 | |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | 0.132 | |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.131 | |
| APOE | apolipoprotein E | 0.128 | |
| FGF10 | fibroblast growth factor 10 | 0.128 | |
| PGF | placental growth factor | 0.124 | |
| NRP1 | neuropilin 1 | 0.122 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.122 | |
| PELI3 | pellino homolog 3 (Drosophila) | 0.120 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.118 | |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.118 | |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.117 | |
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.117 | |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.115 | |
| RUNX1 | runt-related transcription factor 1 | 0.112 | |
| EDN1 | endothelin 1 | 0.111 | |
| KITLG | KIT ligand | 0.111 | |
| IL6R | interleukin 6 receptor | 0.111 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.107 | |
| DCN | decorin | 0.098 | |
| IL23A | interleukin 23, alpha subunit p19 | 0.097 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.094 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.092 | |
| IL1B | interleukin 1, beta | 0.091 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.085 | |
| C3 | complement component 3 | 0.083 | |
| CREBBP | CREB binding protein | 0.077 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.077 | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.076 | |
| IL2RB | interleukin 2 receptor, beta | 0.075 | |
| RARA | retinoic acid receptor, alpha | 0.074 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.071 | |
| A2M | alpha-2-macroglobulin | 0.066 | |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.065 | |
| ATF5 | activating transcription factor 5 | 0.064 | |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.064 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.063 | |
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.059 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.058 | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.057 | |
| IGF2R | insulin-like growth factor 2 receptor | 0.057 | |
| HR | hairless homolog (mouse) | 0.056 | |
| JAK1 | Janus kinase 1 | 0.055 | |
| PLCG1 | phospholipase C, gamma 1 | 0.055 | |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.054 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.054 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.338 | |
| Clic4 | chloride intracellular channel 4 | 0.324 | |
| Flt1 | FMS-related tyrosine kinase 1 | 0.276 | |
| Ednrb | endothelin receptor type B | 0.193 | |
| Slc8a3 | solute carrier family 8 (sodium/calcium exchanger), member 3 | 0.175 | |
| Phkg1 | phosphorylase kinase, gamma 1 | 0.159 | |
| Ctsj | cathepsin J | 0.155 | |
| LOC100362824 | caveolin 2-like | 0.147 | |
| Gper | G protein-coupled estrogen receptor 1 | 0.146 | |
| Smad7 | SMAD family member 7 | 0.145 | |
| Gnb2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.141 | |
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.139 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.135 | |
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.132 | |
| Gja5 | gap junction protein, alpha 5 | 0.130 | |
| Adrb1 | adrenergic, beta-1-, receptor | 0.121 | |
| Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.119 | |
| Il9r | interleukin 9 receptor | 0.117 | |
| Dmd | dystrophin | 0.113 | |
| Kitlg | KIT ligand | 0.113 | |
| Rgs14 | regulator of G-protein signaling 14 | 0.111 | |
| Lifr | leukemia inhibitory factor receptor alpha | 0.103 | |
| Klf13 | Kruppel-like factor 13 | 0.103 | |
| Litaf | lipopolysaccharide-induced TNF factor | 0.095 | |
| Trhr | thyrotropin releasing hormone receptor | 0.094 | |
| Cbl | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.092 | |
| Prkcg | protein kinase C, gamma | 0.086 | |
| Syt4 | synaptotagmin IV | 0.086 | |
| Sirpa | signal-regulatory protein alpha | 0.086 | |
| Apoa5 | apolipoprotein A-V | 0.085 | |
| Olr837 | olfactory receptor 837 | 0.083 | |
| Bmp6 | bone morphogenetic protein 6 | 0.083 | |
| Fli1 | Friend leukemia virus integration 1 | 0.082 | |
| Abcc6 | ATP-binding cassette, subfamily C (CFTR/MRP), member 6 | 0.080 | |
| Eef2 | eukaryotic translation elongation factor 2 | 0.080 | |
| Agxt2 | alanine-glyoxylate aminotransferase 2 | 0.078 | |
| Irs1 | insulin receptor substrate 1 | 0.078 | |
| Car5a | carbonic anhydrase 5a, mitochondrial | 0.077 | |
| Timp3 | TIMP metallopeptidase inhibitor 3 | 0.076 | |
| Msn | moesin | 0.075 | |
| Prlhr | prolactin releasing hormone receptor | 0.074 | |
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.073 | |
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.073 | |
| Il13ra1 | interleukin 13 receptor, alpha 1 | 0.072 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.072 | |
| Ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.072 | |
| Igfals | insulin-like growth factor binding protein, acid labile subunit | 0.071 | |
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.071 | |
| Abcb4 | ATP-binding cassette, subfamily B (MDR/TAP), member 4 | 0.070 | |
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.070 | |
| Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.070 | |
| Myh9 | myosin, heavy chain 9, non-muscle | 0.069 | |
| Vom2r27 | vomeronasal 2 receptor, 27 | 0.069 | |
| Cd4 | Cd4 molecule | 0.068 | |
| Gas7 | growth arrest specific 7 | 0.068 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.068 | |
| Emp1 | epithelial membrane protein 1 | 0.068 | |
| Itpkb | inositol 1,4,5-trisphosphate 3-kinase B | 0.066 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.066 | |
| Trhr2 | thyrotropin releasing hormone receptor 2 | 0.065 | |
| Agxt | alanine-glyoxylate aminotransferase | 0.065 | |
| Dact3 | dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis) | 0.065 | |
| Gja1 | gap junction protein, alpha 1 | 0.064 | |
| Fshb | follicle stimulating hormone, beta polypeptide | 0.064 | |
| Pou3f2 | POU class 3 homeobox 2 | 0.063 | |
| Podxl | podocalyxin-like | 0.062 | |
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.062 | |
| Mrgprf | MAS-related GPR, member F | 0.061 | |
| Kcnh7 | potassium voltage-gated channel, subfamily H (eag-related), member 7 | 0.061 | |
| Cav1 | caveolin 1, caveolae protein | 0.061 | |
| Crhbp | corticotropin releasing hormone binding protein | 0.061 | |
| Gc | group specific component | 0.060 | |
| Synpo | synaptopodin | 0.060 | |
| Dusp1 | dual specificity phosphatase 1 | 0.060 | |
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.059 | |
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.058 | |
| Ddr2 | discoidin domain receptor tyrosine kinase 2 | 0.057 | |
| Cela1 | chymotrypsin-like elastase family, member 1 | 0.057 | |
| Il1r1 | interleukin 1 receptor, type I | 0.057 | |
| Nrg1 | neuregulin 1 | 0.056 | |
| Vcsa2 | variable coding sequence A2 | 0.056 | |
| Cpxm2 | carboxypeptidase X (M14 family), member 2 | 0.056 | |
| Ttl | tubulin tyrosine ligase | 0.056 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.056 | |
| Elovl5 | ELOVL family member 5, elongation of long chain fatty acids (yeast) | 0.055 | |
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.055 | |
| Smad1 | SMAD family member 1 | 0.055 | |
| Trpm8 | transient receptor potential cation channel, subfamily M, member 8 | 0.054 | |
| Grb2 | growth factor receptor bound protein 2 | 0.054 | |
| Clock | clock homolog (mouse) | 0.054 | |
| Ghrh | growth hormone releasing hormone | 0.054 | |
| Plat | plasminogen activator, tissue | 0.054 | |
| Gstm3 | glutathione S-transferase mu 3 | 0.053 | |
| Foxs1 | forkhead box S1 | 0.053 | |
| Slc28a3 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 | 0.053 | |
| Lgals5 | lectin, galactose binding, soluble 5 | 0.053 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.053 | |
| Prl8a7 | prolactin family 8, subfamily a, member 7 | 0.053 | |
| Nox1 | NADPH oxidase 1 | 0.053 | |
| Foxc1 | forkhead box C1 | 0.052 |