The network for 'embryonic placenta development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic placenta development

The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 1.000
Shh sonic hedgehog 0.999
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.999
Fgf8 fibroblast growth factor 8 0.998
Foxc1 forkhead box C1 0.998
Pitx2 paired-like homeodomain transcription factor 2 0.997
Hand2 heart and neural crest derivatives expressed transcript 2 0.996
Ctnnb1 catenin (cadherin associated protein), beta 1 0.994
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.993
Hand1 heart and neural crest derivatives expressed transcript 1 0.992
Hif1a hypoxia inducible factor 1, alpha subunit 0.991
Gata4 GATA binding protein 4 0.989
Fgf10 fibroblast growth factor 10 0.985
Notch2 Notch gene homolog 2 (Drosophila) 0.980
Egfr epidermal growth factor receptor 0.980
Gata6 GATA binding protein 6 0.978
Rxra retinoid X receptor alpha 0.978
Gli3 GLI-Kruppel family member GLI3 0.976
Foxc2 forkhead box C2 0.967
Jag1 jagged 1 0.965
Foxa2 forkhead box A2 0.963
Vegfa vascular endothelial growth factor A 0.960
Pten phosphatase and tensin homolog 0.957
Cdx2 caudal type homeobox 2 0.954
Efnb2 ephrin B2 0.946
Otx2 orthodenticle homolog 2 (Drosophila) 0.942
Pax2 paired box gene 2 0.939
Lepr leptin receptor 0.928
Smad6 MAD homolog 6 (Drosophila) 0.922
Foxg1 forkhead box G1 0.921
Stat3 signal transducer and activator of transcription 3 0.918
Rarg retinoic acid receptor, gamma 0.911
Tbx3 T-box 3 0.897
Hoxd13 homeobox D13 0.896
Pitx1 paired-like homeodomain transcription factor 1 0.892
Bmp4 bone morphogenetic protein 4 0.875
Tcfap2c transcription factor AP-2, gamma 0.875
Ptgs2 prostaglandin-endoperoxide synthase 2 0.875
Neurog1 neurogenin 1 0.871
Wt1 Wilms tumor 1 homolog 0.870
Dlx5 distal-less homeobox 5 0.866
Tbx1 T-box 1 0.861
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.857
Krt17 keratin 17 0.854
Tcfap2a transcription factor AP-2, alpha 0.850
Hoxa1 homeobox A1 0.849
Sox9 SRY-box containing gene 9 0.846
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.843
Adra2b adrenergic receptor, alpha 2b 0.839
Tlx3 T-cell leukemia, homeobox 3 0.834
Nos3 nitric oxide synthase 3, endothelial cell 0.825
Fos FBJ osteosarcoma oncogene 0.824
Mecom MDS1 and EVI1 complex locus 0.818
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.802
Vhl von Hippel-Lindau tumor suppressor 0.801
Neurog2 neurogenin 2 0.796
Tbx5 T-box 5 0.792
Pcdh12 protocadherin 12 0.783
Notch1 Notch gene homolog 1 (Drosophila) 0.781
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.779
Tal1 T-cell acute lymphocytic leukemia 1 0.779
Alx4 aristaless-like homeobox 4 0.777
Padi3 peptidyl arginine deiminase, type III 0.774
Pax3 paired box gene 3 0.772
Trp63 transformation related protein 63 0.765
Hes5 hairy and enhancer of split 5 (Drosophila) 0.762
Wnt7a wingless-related MMTV integration site 7A 0.761
Vangl2 vang-like 2 (van gogh, Drosophila) 0.754
Sox2 SRY-box containing gene 2 0.754
Hoxd11 homeobox D11 0.750
Lhx3 LIM homeobox protein 3 0.745
Pax8 paired box gene 8 0.731
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.725
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.724
Chd7 chromodomain helicase DNA binding protein 7 0.722
Esr1 estrogen receptor 1 (alpha) 0.722
Myod1 myogenic differentiation 1 0.716
Wnt5a wingless-related MMTV integration site 5A 0.713
Kit kit oncogene 0.710
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.705
Tbx2 T-box 2 0.704
Csf1 colony stimulating factor 1 (macrophage) 0.703
Gdnf glial cell line derived neurotrophic factor 0.702
Crebbp CREB binding protein 0.698
Wnt3a wingless-related MMTV integration site 3A 0.696
Krt5 keratin 5 0.694
Gpc3 glypican 3 0.688
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.653
Tgfb2 transforming growth factor, beta 2 0.643
Gli2 GLI-Kruppel family member GLI2 0.641
Nodal nodal 0.633
Jun Jun oncogene 0.626
Ntf3 neurotrophin 3 0.623
Lhx1 LIM homeobox protein 1 0.622
Hes1 hairy and enhancer of split 1 (Drosophila) 0.617
Hoxa13 homeobox A13 0.610
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.607
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.600
Epas1 endothelial PAS domain protein 1 0.591
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
SP1 Sp1 transcription factor 1.000
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.996
EP300 E1A binding protein p300 0.996
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.952
EPAS1 endothelial PAS domain protein 1 0.951
NCOA3 nuclear receptor coactivator 3 0.947
CREBBP CREB binding protein 0.937
SMAD3 SMAD family member 3 0.934
ESR1 estrogen receptor 1 0.902
STK4 serine/threonine kinase 4 0.842
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.838
EGR1 early growth response 1 0.820
NCOR1 nuclear receptor corepressor 1 0.798
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.777
NCOA2 nuclear receptor coactivator 2 0.776
KRT6B keratin 6B 0.766
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.687
SKIL SKI-like oncogene 0.631
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.631
POU5F1 POU class 5 homeobox 1 0.612
RARA retinoic acid receptor, alpha 0.601
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.570
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.544
KAT2B K(lysine) acetyltransferase 2B 0.541
MAPK14 mitogen-activated protein kinase 14 0.531
RUNX1 runt-related transcription factor 1 0.486
FBXL12 F-box and leucine-rich repeat protein 12 0.485
FGF1 fibroblast growth factor 1 (acidic) 0.483
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.473
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.455
NCOA1 nuclear receptor coactivator 1 0.429
TAL1 T-cell acute lymphocytic leukemia 1 0.426
MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 0.425
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.412
GADD45B growth arrest and DNA-damage-inducible, beta 0.406
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.402
RXRA retinoid X receptor, alpha 0.390
CREB1 cAMP responsive element binding protein 1 0.373
STK3 serine/threonine kinase 3 0.358
HSPB1 heat shock 27kDa protein 1 0.356
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.325
SAV1 salvador homolog 1 (Drosophila) 0.305
FGF10 fibroblast growth factor 10 0.301
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.298
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.297
MAPK1 mitogen-activated protein kinase 1 0.289
SMAD2 SMAD family member 2 0.281
HIPK2 homeodomain interacting protein kinase 2 0.278
BHLHE40 basic helix-loop-helix family, member e40 0.278
DUSP1 dual specificity phosphatase 1 0.270
SMAD4 SMAD family member 4 0.268
FAM46A family with sequence similarity 46, member A 0.265
TP53 tumor protein p53 0.262
NCOR2 nuclear receptor corepressor 2 0.254
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.254
AHR aryl hydrocarbon receptor 0.249
BAG1 BCL2-associated athanogene 0.247
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.245
MTA1 metastasis associated 1 0.242
NOTCH1 notch 1 0.241
BAG3 BCL2-associated athanogene 3 0.232
YY1 YY1 transcription factor 0.228
MED13 mediator complex subunit 13 0.225
PUM2 pumilio homolog 2 (Drosophila) 0.225
MAX MYC associated factor X 0.218
TCF4 transcription factor 4 0.211
NIPBL Nipped-B homolog (Drosophila) 0.211
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.209
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.204
PIAS1 protein inhibitor of activated STAT, 1 0.204
KRT18 keratin 18 0.200
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.198
JUN jun proto-oncogene 0.193
EGLN3 egl nine homolog 3 (C. elegans) 0.193
ARNT aryl hydrocarbon receptor nuclear translocator 0.190
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.190
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.187
HSPA8 heat shock 70kDa protein 8 0.187
STAT5A signal transducer and activator of transcription 5A 0.186
CTGF connective tissue growth factor 0.183
EGLN1 egl nine homolog 1 (C. elegans) 0.181
FOS FBJ murine osteosarcoma viral oncogene homolog 0.181
VEZF1 vascular endothelial zinc finger 1 0.177
JUB jub, ajuba homolog (Xenopus laevis) 0.174
CENPJ centromere protein J 0.164
SPEN spen homolog, transcriptional regulator (Drosophila) 0.157
PEBP4 phosphatidylethanolamine-binding protein 4 0.157
TCF12 transcription factor 12 0.157
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.155
FGF7 fibroblast growth factor 7 0.153
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.151
MTA3 metastasis associated 1 family, member 3 0.148
IER2 immediate early response 2 0.144
MAP1S microtubule-associated protein 1S 0.139
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.137
TRRAP transformation/transcription domain-associated protein 0.135
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.134
MED25 mediator complex subunit 25 0.134
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.132
TRIM33 tripartite motif containing 33 0.130
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Rattus norvegicus
Name Description Probability Func Analog Organism
Junb jun B proto-oncogene 0.472
Krt18 keratin 18 0.180
Egr1 early growth response 1 0.159
Errfi1 ERBB receptor feedback inhibitor 1 0.082
Cald1 caldesmon 1 0.078
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.071
Nfya nuclear transcription factor-Y alpha 0.057
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.053
Ier3 immediate early response 3 0.041
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.035
Jak1 Janus kinase 1 0.035
RGD1564560 similar to RCK 0.034
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.033
Marcks myristoylated alanine rich protein kinase C substrate 0.032
Vegfa vascular endothelial growth factor A 0.029
Sp1 Sp1 transcription factor 0.029
Zfp36 zinc finger protein 36 0.029
Jarid1a jumonji, AT rich interactive domain 1A (Rbp2 like) 0.026
Stk3 serine/threonine kinase 3 (STE20 homolog, yeast) 0.026
Tgfbr2 transforming growth factor, beta receptor II 0.026
Foxe3 forkhead box E3 0.025
Nab1 Ngfi-A binding protein 1 0.025
Cebpd CCAAT/enhancer binding protein (C/EBP), delta 0.025
Cyth1 cytohesin 1 0.025
Jun Jun oncogene 0.024
Smad7 SMAD family member 7 0.024
Hnrnpl heterogeneous nuclear ribonucleoprotein L 0.023
Arf5 ADP-ribosylation factor 5 0.022
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.022
Hfe hemochromatosis 0.021
RGD1309414 similar to KIAA0913 protein 0.021
Cd38 CD38 molecule 0.020
Bmp4 bone morphogenetic protein 4 0.020
Add3 adducin 3 (gamma) 0.020
Foxo1 forkhead box O1 0.020
Mapk1 mitogen activated protein kinase 1 0.019
Zbtb41 zinc finger and BTB domain containing 41 0.019
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.019
Cpne3 copine III 0.019
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.019
Sf1 splicing factor 1 0.018
Dusp1 dual specificity phosphatase 1 0.018
St13 suppression of tumorigenicity 13 0.018
Casp1 caspase 1 0.018
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.018
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.018
Picalm phosphatidylinositol binding clathrin assembly protein 0.017
Krt19 keratin 19 0.017
RGD1310351 similar to RIKEN cDNA 4732418C07 0.017
Cpb1 carboxypeptidase B1 (tissue) 0.017
Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.017
Btg2 BTG family, member 2 0.017
Akap1 A kinase (PRKA) anchor protein 1 0.016
Kif15 kinesin family member 15 0.016
Hspa1a heat shock 70kD protein 1A 0.016
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.016
Bmp7 bone morphogenetic protein 7 0.016
Wipf1 WAS/WASL interacting protein family, member 1 0.016
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.016
Gper G protein-coupled estrogen receptor 1 0.016
Cyfip1 cytoplasmic FMR1 interacting protein 1 0.016
Cyb5r1 cytochrome b5 reductase 1 0.016
Sdc3 syndecan 3 0.016
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.016
Bglap bone gamma-carboxyglutamate (gla) protein 0.015
Fos FBJ osteosarcoma oncogene 0.015
Prkca protein kinase C, alpha 0.015
Epcam epithelial cell adhesion molecule 0.015
Slc44a4 solute carrier family 44, member 4 0.015
Itga1 integrin, alpha 1 0.015
Fmr1 fragile X mental retardation 1 0.015
Nfia nuclear factor I/A 0.015
Mprip myosin phosphatase Rho interacting protein 0.015
Socs2 suppressor of cytokine signaling 2 0.014
Cpsf2 cleavage and polyadenylation specific factor 2 0.014
Mga MAX gene associated 0.014
Vdac1 voltage-dependent anion channel 1 0.014
Adam9 ADAM metallopeptidase domain 9 (meltrin gamma) 0.014
Sppl2a signal peptide peptidase-like 2A 0.014
Casp3 caspase 3 0.014
Mapk6 mitogen-activated protein kinase 6 0.014
Aqp9 aquaporin 9 0.014
Zbtb20 zinc finger and BTB domain containing 20 0.014
Trim23 tripartite motif-containing 23 0.014
Fosl2 fos-like antigen 2 0.013
Vhl von Hippel-Lindau tumor suppressor 0.013
Ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.013
Bat2d1 BAT2 domain containing 1 0.013
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.013
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.013
Fkbp4 FK506 binding protein 4 0.013
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.013
Cpb2 carboxypeptidase B2 (plasma) 0.013
Cish cytokine inducible SH2-containing protein 0.013
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.013
Pyy peptide YY (mapped) 0.013
A1bg alpha-1-B glycoprotein 0.012
Nfix nuclear factor I/X (CCAAT-binding transcription factor) 0.012
Gdf15 growth differentiation factor 15 0.012
Wasl Wiskott-Aldrich syndrome-like 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism