IMP
Process View
The network for 'fc receptor mediated inhibitory signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
fc receptor mediated inhibitory signaling pathway
A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ikzf1 | IKAROS family zinc finger 1 | 0.891 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.640 | |
| Cd19 | CD19 antigen | 0.556 | |
| Was | Wiskott-Aldrich syndrome homolog (human) | 0.465 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.312 | |
| Cd22 | CD22 antigen | 0.292 | |
| Fyn | Fyn proto-oncogene | 0.245 | |
| Plcg2 | phospholipase C, gamma 2 | 0.235 | |
| Lck | lymphocyte protein tyrosine kinase | 0.223 | |
| Hcls1 | hematopoietic cell specific Lyn substrate 1 | 0.200 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.200 | |
| Cd247 | CD247 antigen | 0.178 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.159 | |
| Cbl | Casitas B-lineage lymphoma | 0.147 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.142 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.128 | |
| Fyb | FYN binding protein | 0.121 | |
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.109 | |
| Clnk | cytokine-dependent hematopoietic cell linker | 0.109 | |
| Cd40 | CD40 antigen | 0.107 | |
| Ptpre | protein tyrosine phosphatase, receptor type, E | 0.107 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.091 | |
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.089 | |
| Dok2 | docking protein 2 | 0.087 | |
| Blnk | B-cell linker | 0.081 | |
| Itgax | integrin alpha X | 0.076 | |
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.073 | |
| Lyl1 | lymphoblastomic leukemia 1 | 0.071 | |
| Lat | linker for activation of T cells | 0.062 | |
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.061 | |
| Rasa1 | RAS p21 protein activator 1 | 0.061 | |
| Laptm5 | lysosomal-associated protein transmembrane 5 | 0.060 | |
| Prkce | protein kinase C, epsilon | 0.059 | |
| Dok1 | docking protein 1 | 0.058 | |
| Itgb2 | integrin beta 2 | 0.057 | |
| Foxn1 | forkhead box N1 | 0.056 | |
| Cd180 | CD180 antigen | 0.055 | |
| Tnf | tumor necrosis factor | 0.053 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.051 | |
| Cybb | cytochrome b-245, beta polypeptide | 0.049 | |
| AF251705 | cDNA sequence AF251705 | 0.047 | |
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.046 | |
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.045 | |
| Cd8a | CD8 antigen, alpha chain | 0.041 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.041 | |
| Wipf1 | WAS/WASL interacting protein family, member 1 | 0.041 | |
| Cd4 | CD4 antigen | 0.040 | |
| Sykb | spleen tyrosine kinase | 0.039 | |
| Igh | immunoglobulin heavy chain complex | 0.038 | |
| Hck | hemopoietic cell kinase | 0.037 | |
| Cd7 | CD7 antigen | 0.036 | |
| Cd5 | CD5 antigen | 0.036 | |
| Sash3 | SAM and SH3 domain containing 3 | 0.035 | |
| Cd37 | CD37 antigen | 0.035 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.035 | |
| BC013712 | cDNA sequence BC013712 | 0.035 | |
| Bcar1 | breast cancer anti-estrogen resistance 1 | 0.034 | |
| Zap70 | zeta-chain (TCR) associated protein kinase | 0.034 | |
| Cd72 | CD72 antigen | 0.032 | |
| Slc34a2 | solute carrier family 34 (sodium phosphate), member 2 | 0.032 | |
| Apobec1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 0.032 | |
| Icos | inducible T-cell co-stimulator | 0.032 | |
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.031 | |
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.030 | |
| Rac2 | RAS-related C3 botulinum substrate 2 | 0.030 | |
| Cd28 | CD28 antigen | 0.030 | |
| Cd8b1 | CD8 antigen, beta chain 1 | 0.030 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.029 | |
| Myo1f | myosin IF | 0.029 | |
| Nfam1 | Nfat activating molecule with ITAM motif 1 | 0.029 | |
| Pxn | paxillin | 0.028 | |
| Itgal | integrin alpha L | 0.028 | |
| Cdcp1 | CUB domain containing protein 1 | 0.028 | |
| Csf1r | colony stimulating factor 1 receptor | 0.028 | |
| Rgs14 | regulator of G-protein signaling 14 | 0.027 | |
| Lcp2 | lymphocyte cytosolic protein 2 | 0.027 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.027 | |
| Myo1g | myosin IG | 0.026 | |
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.026 | |
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.026 | |
| Ctsw | cathepsin W | 0.025 | |
| Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.025 | |
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.025 | |
| Ifng | interferon gamma | 0.025 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.024 | |
| Mcoln2 | mucolipin 2 | 0.024 | |
| Cd96 | CD96 antigen | 0.024 | |
| Fpr1 | formyl peptide receptor 1 | 0.024 | |
| Rasal3 | RAS protein activator like 3 | 0.024 | |
| Ciita | class II transactivator | 0.024 | |
| Ptprcap | protein tyrosine phosphatase, receptor type, C polypeptide-associated protein | 0.023 | |
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.023 | |
| Fam83f | family with sequence similarity 83, member F | 0.023 | |
| Xcr1 | chemokine (C motif) receptor 1 | 0.023 | |
| Khdrbs1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.023 | |
| Il4 | interleukin 4 | 0.023 | |
| Gpr97 | G protein-coupled receptor 97 | 0.023 | |
| Ngp | neutrophilic granule protein | 0.022 | |
| Hcst | hematopoietic cell signal transducer | 0.022 | |
| Mefv | Mediterranean fever | 0.022 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 1.000 | |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 1.000 | |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 1.000 | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.999 | |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.999 | |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.943 | |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.934 | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.849 | |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.828 | |
| PTAFR | platelet-activating factor receptor | 0.820 | |
| HK3 | hexokinase 3 (white cell) | 0.763 | |
| TYMP | thymidine phosphorylase | 0.532 | |
| CD33 | CD33 molecule | 0.334 | |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.133 | |
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.129 | |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.108 | |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.102 | |
| CSK | c-src tyrosine kinase | 0.078 | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.075 | |
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.074 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.070 | |
| CD86 | CD86 molecule | 0.068 | |
| NLRP3 | NLR family, pyrin domain containing 3 | 0.064 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.063 | |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 | 0.061 | |
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.054 | |
| CYTH4 | cytohesin 4 | 0.052 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.051 | |
| DOCK7 | dedicator of cytokinesis 7 | 0.046 | |
| CD300A | CD300a molecule | 0.046 | |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.044 | |
| AIF1 | allograft inflammatory factor 1 | 0.042 | |
| CD300C | CD300c molecule | 0.042 | |
| FPR2 | formyl peptide receptor 2 | 0.040 | |
| HCK | hemopoietic cell kinase | 0.034 | |
| TLR8 | toll-like receptor 8 | 0.033 | |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.032 | |
| MARCO | macrophage receptor with collagenous structure | 0.031 | |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 | 0.030 | |
| CD163 | CD163 molecule | 0.029 | |
| DPEP2 | dipeptidase 2 | 0.028 | |
| FPR1 | formyl peptide receptor 1 | 0.028 | |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.027 | |
| SLC15A3 | solute carrier family 15, member 3 | 0.026 | |
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.024 | |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 | 0.022 | |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.022 | |
| CFP | complement factor properdin | 0.021 | |
| CMKLR1 | chemokine-like receptor 1 | 0.019 | |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.019 | |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 | 0.018 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.018 | |
| AQP9 | aquaporin 9 | 0.018 | |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | 0.017 | |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.016 | |
| HLA-G | major histocompatibility complex, class I, G | 0.016 | |
| SIRPA | signal-regulatory protein alpha | 0.016 | |
| S100A12 | S100 calcium binding protein A12 | 0.016 | |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | 0.016 | |
| BIN2 | bridging integrator 2 | 0.016 | |
| CLEC5A | C-type lectin domain family 5, member A | 0.016 | |
| IL1RN | interleukin 1 receptor antagonist | 0.015 | |
| APOBR | apolipoprotein B receptor | 0.014 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.013 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.013 | |
| ASGR2 | asialoglycoprotein receptor 2 | 0.013 | |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.012 | |
| EMR3 | egf-like module containing, mucin-like, hormone receptor-like 3 | 0.012 | |
| FCAR | Fc fragment of IgA, receptor for | 0.012 | |
| EPOR | erythropoietin receptor | 0.011 | |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.011 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.011 | |
| BEST1 | bestrophin 1 | 0.011 | |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.011 | |
| HAMP | hepcidin antimicrobial peptide | 0.011 | |
| FOLR3 | folate receptor 3 (gamma) | 0.010 |