The network for 'regulation of mast cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mast cell differentiation

Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Hand2 heart and neural crest derivatives expressed transcript 2 0.999
Otx2 orthodenticle homolog 2 (Drosophila) 0.999
Neurod1 neurogenic differentiation 1 0.999
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.998
Gata4 GATA binding protein 4 0.997
Stat3 signal transducer and activator of transcription 3 0.996
Isl1 ISL1 transcription factor, LIM/homeodomain 0.996
Pax3 paired box gene 3 0.993
Neurog2 neurogenin 2 0.992
Pax6 paired box gene 6 0.989
Neurod4 neurogenic differentiation 4 0.989
Gli2 GLI-Kruppel family member GLI2 0.981
Ptf1a pancreas specific transcription factor, 1a 0.979
Msx1 homeobox, msh-like 1 0.976
Irf9 interferon regulatory factor 9 0.970
Hand1 heart and neural crest derivatives expressed transcript 1 0.967
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.933
Foxc2 forkhead box C2 0.903
Gata1 GATA binding protein 1 0.902
Trp53 transformation related protein 53 0.892
Pitx2 paired-like homeodomain transcription factor 2 0.892
Onecut1 one cut domain, family member 1 0.875
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.861
Lep leptin 0.858
Fgf8 fibroblast growth factor 8 0.845
Tcfap2a transcription factor AP-2, alpha 0.787
Prlr prolactin receptor 0.763
Foxp3 forkhead box P3 0.754
Gsc goosecoid homeobox 0.752
Pdx1 pancreatic and duodenal homeobox 1 0.744
En1 engrailed 1 0.735
Tgfb1 transforming growth factor, beta 1 0.722
Prrx1 paired related homeobox 1 0.699
Sox9 SRY-box containing gene 9 0.697
Mecom MDS1 and EVI1 complex locus 0.693
Stat1 signal transducer and activator of transcription 1 0.690
Kiss1 KiSS-1 metastasis-suppressor 0.686
Prph2 peripherin 2 0.652
Tgfb2 transforming growth factor, beta 2 0.641
Lhx5 LIM homeobox protein 5 0.626
Il10 interleukin 10 0.616
Sox11 SRY-box containing gene 11 0.587
Nkx3-2 NK3 homeobox 2 0.565
Emx1 empty spiracles homolog 1 (Drosophila) 0.543
Dlx2 distal-less homeobox 2 0.531
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.529
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.528
Prrx2 paired related homeobox 2 0.520
Lepr leptin receptor 0.512
Cbfa2t3 core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) 0.506
Gli3 GLI-Kruppel family member GLI3 0.477
Gpr50 G-protein-coupled receptor 50 0.472
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.470
Hoxa1 homeobox A1 0.467
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.463
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.455
Gata6 GATA binding protein 6 0.453
Rxra retinoid X receptor alpha 0.445
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.439
Zeb1 zinc finger E-box binding homeobox 1 0.433
Pou4f2 POU domain, class 4, transcription factor 2 0.428
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.416
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.415
Myd88 myeloid differentiation primary response gene 88 0.412
Insm1 insulinoma-associated 1 0.408
Neurog3 neurogenin 3 0.406
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.405
Gnrhr gonadotropin releasing hormone receptor 0.404
Alx3 aristaless-like homeobox 3 0.404
Gbx2 gastrulation brain homeobox 2 0.399
Lhx3 LIM homeobox protein 3 0.399
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.385
Efna2 ephrin A2 0.383
Pax9 paired box gene 9 0.382
Hoxd13 homeobox D13 0.372
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.365
Ntf3 neurotrophin 3 0.363
Dlx5 distal-less homeobox 5 0.363
Lhx9 LIM homeobox protein 9 0.357
Nhlh1 nescient helix loop helix 1 0.347
Tlx3 T-cell leukemia, homeobox 3 0.329
Smo smoothened homolog (Drosophila) 0.321
Shox2 short stature homeobox 2 0.318
Zic1 zinc finger protein of the cerebellum 1 0.309
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.308
Ebf3 early B-cell factor 3 0.302
Gdf11 growth differentiation factor 11 0.297
Atoh7 atonal homolog 7 (Drosophila) 0.292
Nos3 nitric oxide synthase 3, endothelial cell 0.290
Hoxd3 homeobox D3 0.289
Prox1 prospero-related homeobox 1 0.285
Socs1 suppressor of cytokine signaling 1 0.285
Foxa2 forkhead box A2 0.274
Stat6 signal transducer and activator of transcription 6 0.271
Fgf15 fibroblast growth factor 15 0.267
Hoxc5 homeobox C5 0.260
Lgals9 lectin, galactose binding, soluble 9 0.258
Hic1 hypermethylated in cancer 1 0.253
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.242
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism