The network for 't cell mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

t cell mediated immunity

Any process involved in the carrying out of an immune response by a T cell.

Mus musculus
Name Description Probability Func Analog Organism
H2-K1 histocompatibility 2, K1, K region 0.994
H2-Q7 histocompatibility 2, Q region locus 7 0.943
Cd40 CD40 antigen 0.914
Clec4d C-type lectin domain family 4, member d 0.888
Ccl5 chemokine (C-C motif) ligand 5 0.797
Prf1 perforin 1 (pore forming protein) 0.794
Pnp2 purine-nucleoside phosphorylase 2 0.787
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.766
H2-D1 histocompatibility 2, D region locus 1 0.749
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.713
Casp8 caspase 8 0.629
Tapbp TAP binding protein 0.615
Fyn Fyn proto-oncogene 0.595
Rab27a RAB27A, member RAS oncogene family 0.554
Fcna ficolin A 0.548
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.519
Ccl22 chemokine (C-C motif) ligand 22 0.494
B2m beta-2 microglobulin 0.453
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.447
Ccl8 chemokine (C-C motif) ligand 8 0.435
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.364
Lyz2 lysozyme 2 0.361
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.340
Tnf tumor necrosis factor 0.338
Il2rg interleukin 2 receptor, gamma chain 0.335
Irf1 interferon regulatory factor 1 0.327
Ikzf1 IKAROS family zinc finger 1 0.326
Itgb2 integrin beta 2 0.324
Ifngr1 interferon gamma receptor 1 0.322
Birc3 baculoviral IAP repeat-containing 3 0.321
Spna1 spectrin alpha 1 0.304
Ccr1 chemokine (C-C motif) receptor 1 0.298
Igh immunoglobulin heavy chain complex 0.295
Il1b interleukin 1 beta 0.287
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.279
Cd28 CD28 antigen 0.278
Xcl1 chemokine (C motif) ligand 1 0.270
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.267
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.258
Itgax integrin alpha X 0.254
Cd209d CD209d antigen 0.254
Ccr7 chemokine (C-C motif) receptor 7 0.243
Cd4 CD4 antigen 0.242
Cma1 chymase 1, mast cell 0.242
Cd209b CD209b antigen 0.240
Clec4e C-type lectin domain family 4, member e 0.238
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.230
Il2rb interleukin 2 receptor, beta chain 0.229
Gzma granzyme A 0.211
Mmp12 matrix metallopeptidase 12 0.210
Traf6 TNF receptor-associated factor 6 0.206
Shisa5 shisa homolog 5 (Xenopus laevis) 0.203
Icos inducible T-cell co-stimulator 0.196
Sh2d2a SH2 domain protein 2A 0.191
Il10rb interleukin 10 receptor, beta 0.189
Mmp3 matrix metallopeptidase 3 0.184
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.183
Il12b interleukin 12b 0.177
Ikbkg inhibitor of kappaB kinase gamma 0.176
a nonagouti 0.174
Mefv Mediterranean fever 0.173
Lsp1 lymphocyte specific 1 0.170
Ptprc protein tyrosine phosphatase, receptor type, C 0.168
Tnip1 TNFAIP3 interacting protein 1 0.167
Cd209g CD209g antigen 0.163
Selp selectin, platelet 0.162
Anxa1 annexin A1 0.160
Il18rap interleukin 18 receptor accessory protein 0.158
Ccl7 chemokine (C-C motif) ligand 7 0.157
Fas Fas (TNF receptor superfamily member 6) 0.156
Gzmb granzyme B 0.155
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.155
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.155
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.151
Il1rl1 interleukin 1 receptor-like 1 0.149
Nkg7 natural killer cell group 7 sequence 0.147
Mmp10 matrix metallopeptidase 10 0.141
Cd209f CD209f antigen 0.139
Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide 0.138
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 0.135
Ncr1 natural cytotoxicity triggering receptor 1 0.133
Ccl24 chemokine (C-C motif) ligand 24 0.129
Hbb-b1 hemoglobin, beta adult major chain 0.128
Klf1 Kruppel-like factor 1 (erythroid) 0.128
Plaur plasminogen activator, urokinase receptor 0.126
Apbh androgen-binding protein eta 0.126
Litaf LPS-induced TN factor 0.124
Lta lymphotoxin A 0.124
Nckap1l NCK associated protein 1 like 0.123
Il23a interleukin 23, alpha subunit p19 0.123
Ifng interferon gamma 0.122
Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.121
Cd209a CD209a antigen 0.121
Ctsw cathepsin W 0.119
Selplg selectin, platelet (p-selectin) ligand 0.117
Cxcl2 chemokine (C-X-C motif) ligand 2 0.116
Card11 caspase recruitment domain family, member 11 0.116
Jak2 Janus kinase 2 0.115
Cxcl9 chemokine (C-X-C motif) ligand 9 0.115
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.111
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
dlg4 discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila) 0.066
zgc:64115 zgc:64115 0.056
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.040
nod1 nucleotide-binding oligomerization domain containing 1 0.031
tfec transcription factor EC 0.022
irak4 interleukin-1 receptor-associated kinase 4 0.021
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.020
ltk leukocyte tyrosine kinase 0.020
dlb deltaB 0.018
zgc:55891 zgc:55891 0.018
dlg2 discs, large (Drosophila) homolog 2 0.018
hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.018
crestin crestin 0.017
syngr1a synaptogyrin 1a 0.017
notch2 notch homolog 2 0.017
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.016
fcer1gl Fc receptor, IgE, high affinity I, gamma polypeptide like 0.016
cxcr3.2 chemokine (C-X-C motif) receptor 3.2 0.016
LOC557072 caspase recruitment domain-containing protein 11-like 0.015
zgc:152830 zgc:152830 0.015
ahr2 aryl hydrocarbon receptor 2 0.015
ctsba cathepsin B, a 0.014
lrrc33 leucine rich repeat containing 33 0.014
gstt1a glutathione S-transferase theta 1a 0.013
tlr3 toll-like receptor 3 0.013
zgc:162329 zgc:162329 0.012
c1qc complement component 1, q subcomponent, C chain 0.012
celsr1a cadherin EGF LAG seven-pass G-type receptor 1a 0.012
aox3 aldehyde oxidase 3 0.012
coro1a coronin, actin binding protein, 1A 0.011
nfyc nuclear transcription factor Y, gamma 0.011
nadl1.1 neural adhesion molecule L1.1 0.011
brpf1 bromodomain and PHD finger containing, 1 0.011
gpr22 G protein-coupled receptor 22 0.011
bmp3 bone morphogenetic protein 3 0.011
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.011
zgc:63831 zgc:63831 0.011
pdgfab platelet derived growth factor alpha b 0.011
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.011
tbx21 T-box 21 0.011
sc:d173 sc:d173 0.011
st8sia5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 0.011
LOC100004946 transient receptor potential cation channel subfamily M member 4-like 0.010
pkz protein kinase containing Z-DNA binding domains 0.010
jag1b jagged 1b 0.010
itk IL2-inducible T-cell kinase 0.010
gmfg glia maturation factor, gamma 0.010
barx1 BarH-like homeobox 1 0.010
hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 0.010
mfsd7 major facilitator superfamily domain containing 7 0.010
tnfsf10l4 tumor necrosis factor (ligand) superfamily, member 10 like 4 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.959
B2M beta-2-microglobulin 0.932
HLA-B major histocompatibility complex, class I, B 0.818
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.813
HLA-A major histocompatibility complex, class I, A 0.791
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.605
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.586
HLA-G major histocompatibility complex, class I, G 0.555
BTN3A2 butyrophilin, subfamily 3, member A2 0.538
BTN3A3 butyrophilin, subfamily 3, member A3 0.449
HLA-F major histocompatibility complex, class I, F 0.441
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.425
IL4R interleukin 4 receptor 0.424
HLA-C major histocompatibility complex, class I, C 0.417
CCL5 chemokine (C-C motif) ligand 5 0.417
BTN3A1 butyrophilin, subfamily 3, member A1 0.401
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.390
BIRC3 baculoviral IAP repeat containing 3 0.341
CD40 CD40 molecule, TNF receptor superfamily member 5 0.333
NOTCH3 notch 3 0.284
CXCL9 chemokine (C-X-C motif) ligand 9 0.246
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.237
CCR5 chemokine (C-C motif) receptor 5 0.212
NOTCH1 notch 1 0.210
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.183
IL2RG interleukin 2 receptor, gamma 0.179
CD80 CD80 molecule 0.170
SIGLEC7 sialic acid binding Ig-like lectin 7 0.167
SRGN serglycin 0.167
HLA-E major histocompatibility complex, class I, E 0.166
PILRA paired immunoglobin-like type 2 receptor alpha 0.161
CXCL10 chemokine (C-X-C motif) ligand 10 0.159
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.157
CCL8 chemokine (C-C motif) ligand 8 0.144
TRAF1 TNF receptor-associated factor 1 0.132
TAPBP TAP binding protein (tapasin) 0.130
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.113
SNAP23 synaptosomal-associated protein, 23kDa 0.109
CCR1 chemokine (C-C motif) receptor 1 0.100
CXCL11 chemokine (C-X-C motif) ligand 11 0.088
CCL4 chemokine (C-C motif) ligand 4 0.076
CCR7 chemokine (C-C motif) receptor 7 0.074
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 0.070
CCL13 chemokine (C-C motif) ligand 13 0.067
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.061
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.057
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.056
TNF tumor necrosis factor 0.055
SQSTM1 sequestosome 1 0.053
TRIM38 tripartite motif containing 38 0.051
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.050
ICAM1 intercellular adhesion molecule 1 0.048
BTN2A2 butyrophilin, subfamily 2, member A2 0.048
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.046
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.043
NOTCH2 notch 2 0.041
IL10 interleukin 10 0.041
IL10RA interleukin 10 receptor, alpha 0.040
GFI1B growth factor independent 1B transcription repressor 0.039
CCL11 chemokine (C-C motif) ligand 11 0.039
VAMP4 vesicle-associated membrane protein 4 0.038
TGIF1 TGFB-induced factor homeobox 1 0.038
IL1B interleukin 1, beta 0.036
IFNG interferon, gamma 0.035
ADAM17 ADAM metallopeptidase domain 17 0.035
IL8 interleukin 8 0.034
LGALS3 lectin, galactoside-binding, soluble, 3 0.034
IDE insulin-degrading enzyme 0.033
CD163 CD163 molecule 0.033
CCL2 chemokine (C-C motif) ligand 2 0.033
ZMYND11 zinc finger, MYND-type containing 11 0.032
TRAF2 TNF receptor-associated factor 2 0.032
TYMP thymidine phosphorylase 0.031
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.031
CCL22 chemokine (C-C motif) ligand 22 0.031
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.030
OASL 2'-5'-oligoadenylate synthetase-like 0.030
IL15RA interleukin 15 receptor, alpha 0.030
PML promyelocytic leukemia 0.030
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.029
CCL7 chemokine (C-C motif) ligand 7 0.029
PTAFR platelet-activating factor receptor 0.028
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.027
DPP4 dipeptidyl-peptidase 4 0.027
TRADD TNFRSF1A-associated via death domain 0.027
BTN2A1 butyrophilin, subfamily 2, member A1 0.027
CD48 CD48 molecule 0.026
CD247 CD247 molecule 0.026
TJP1 tight junction protein 1 (zona occludens 1) 0.025
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.025
HK3 hexokinase 3 (white cell) 0.025
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.025
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.024
FPR3 formyl peptide receptor 3 0.024
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.023
CALCOCO2 calcium binding and coiled-coil domain 2 0.023
CXCL13 chemokine (C-X-C motif) ligand 13 0.023
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.023
NLRP3 NLR family, pyrin domain containing 3 0.023
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.022
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-EC2 RT1 class Ib, locus EC2 0.343
Hsph1 heat shock 105/110 protein 1 0.139
Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) 0.055
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.044
Stip1 stress-induced phosphoprotein 1 0.029
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.027
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.014
Ccl5 chemokine (C-C motif) ligand 5 0.011
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.011
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.011
Ctsh cathepsin H 0.010
Irf7 interferon regulatory factor 7 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism