The network for 'positive regulation of cell cycle process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell cycle process

Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.

Mus musculus
Name Description Probability Func Analog Organism
Trp53 transformation related protein 53 0.995
Ctnnb1 catenin (cadherin associated protein), beta 1 0.946
Neurod1 neurogenic differentiation 1 0.909
Shh sonic hedgehog 0.884
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.869
Cbl Casitas B-lineage lymphoma 0.834
Pax6 paired box gene 6 0.750
Pax3 paired box gene 3 0.729
Cdk2 cyclin-dependent kinase 2 0.689
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.678
Notch2 Notch gene homolog 2 (Drosophila) 0.627
Pitx2 paired-like homeodomain transcription factor 2 0.572
Gli3 GLI-Kruppel family member GLI3 0.541
Tcf3 transcription factor 3 0.508
Pkd1 polycystic kidney disease 1 homolog 0.461
Hand1 heart and neural crest derivatives expressed transcript 1 0.452
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.446
Hoxd13 homeobox D13 0.434
Hdac1 histone deacetylase 1 0.389
Otx2 orthodenticle homolog 2 (Drosophila) 0.381
Sox2 SRY-box containing gene 2 0.379
Rac1 RAS-related C3 botulinum substrate 1 0.366
Plk1 polo-like kinase 1 (Drosophila) 0.358
Neurog2 neurogenin 2 0.346
Cdk4 cyclin-dependent kinase 4 0.336
Kdr kinase insert domain protein receptor 0.326
Stag1 stromal antigen 1 0.313
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.289
Gdf5 growth differentiation factor 5 0.274
Hes1 hairy and enhancer of split 1 (Drosophila) 0.273
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.270
Ccnb1 cyclin B1 0.264
Grb10 growth factor receptor bound protein 10 0.263
Ccnd1 cyclin D1 0.249
Hoxa13 homeobox A13 0.249
Rb1 retinoblastoma 1 0.241
Id1 inhibitor of DNA binding 1 0.238
Alx4 aristaless-like homeobox 4 0.237
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.237
Mdm2 transformed mouse 3T3 cell double minute 2 0.234
Sox11 SRY-box containing gene 11 0.232
Smad6 MAD homolog 6 (Drosophila) 0.232
Emx1 empty spiracles homolog 1 (Drosophila) 0.220
Adam17 a disintegrin and metallopeptidase domain 17 0.220
Pthlh parathyroid hormone-like peptide 0.215
Vegfa vascular endothelial growth factor A 0.209
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.198
Fgfr2 fibroblast growth factor receptor 2 0.196
Nos3 nitric oxide synthase 3, endothelial cell 0.192
Dab1 disabled homolog 1 (Drosophila) 0.190
Tcf4 transcription factor 4 0.186
Isl1 ISL1 transcription factor, LIM/homeodomain 0.185
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.184
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.181
Lhx3 LIM homeobox protein 3 0.179
Ccna2 cyclin A2 0.172
Ccne1 cyclin E1 0.172
Sox9 SRY-box containing gene 9 0.171
Fgfr1 fibroblast growth factor receptor 1 0.169
Ptf1a pancreas specific transcription factor, 1a 0.168
Gata4 GATA binding protein 4 0.166
Csf1 colony stimulating factor 1 (macrophage) 0.165
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.163
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.153
Plcg1 phospholipase C, gamma 1 0.152
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.152
Rag1 recombination activating gene 1 0.150
Pten phosphatase and tensin homolog 0.148
Arid1a AT rich interactive domain 1A (SWI-like) 0.147
Acan aggrecan 0.146
Myf5 myogenic factor 5 0.146
Pax7 paired box gene 7 0.146
Brca1 breast cancer 1 0.143
Tmpo thymopoietin 0.140
Onecut1 one cut domain, family member 1 0.140
Id3 inhibitor of DNA binding 3 0.135
Gab1 growth factor receptor bound protein 2-associated protein 1 0.134
Wnt3a wingless-related MMTV integration site 3A 0.132
Axin1 axin 1 0.131
Apc adenomatosis polyposis coli 0.130
Ccnb2 cyclin B2 0.128
Pou3f3 POU domain, class 3, transcription factor 3 0.128
Mdm4 transformed mouse 3T3 cell double minute 4 0.128
Mcm3 minichromosome maintenance deficient 3 (S. cerevisiae) 0.126
Lef1 lymphoid enhancer binding factor 1 0.126
Foxc1 forkhead box C1 0.126
Jag1 jagged 1 0.124
Meox2 mesenchyme homeobox 2 0.122
Ccnd2 cyclin D2 0.122
Pax9 paired box gene 9 0.119
Tbx3 T-box 3 0.119
Bmp7 bone morphogenetic protein 7 0.117
Lrp6 low density lipoprotein receptor-related protein 6 0.116
Srsf2 serine/arginine-rich splicing factor 2 0.115
Dnm1 dynamin 1 0.115
Psen1 presenilin 1 0.114
Gsk3b glycogen synthase kinase 3 beta 0.112
En1 engrailed 1 0.112
Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.110
H2afx H2A histone family, member X 0.108
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
trr-1 Protein TRR-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
dap dacapo 0.786
Akt1 CG4006 gene product from transcript CG4006-RA 0.683
CycB Cyclin B 0.560
bsk basket 0.424
malpha E(spl) region transcript malpha 0.348
HLHmbeta E(spl) region transcript mbeta 0.318
asp abnormal spindle 0.228
arm armadillo 0.211
dup double parked 0.186
HLHmdelta E(spl) region transcript mdelta 0.183
HLHm5 E(spl) region transcript m5 0.177
CycE Cyclin E 0.175
HLHmgamma E(spl) region transcript mgamma 0.163
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.157
pbl pebble 0.145
aop anterior open 0.141
Mad Mothers against dpp 0.122
tws twins 0.118
spi spitz 0.118
baz bazooka 0.107
stg string 0.105
eg eagle 0.100
dm diminutive 0.099
SoxN SoxNeuro 0.093
NetB Netrin-B 0.090
myoglianin CG1838 gene product from transcript CG1838-RD 0.089
ari-2 ariadne 2 0.087
numb CG3779 gene product from transcript CG3779-RB 0.086
dsh dishevelled 0.086
BicD Bicaudal D 0.086
HLHm7 E(spl) region transcript m7 0.083
brat brain tumor 0.081
ttk tramtrack 0.081
CycA Cyclin A 0.079
spn-B spindle B 0.077
orb oo18 RNA-binding protein 0.076
Chro Chromator 0.075
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.074
Psf2 CG18013 gene product from transcript CG18013-RA 0.073
nej nejire 0.073
Det Deterin 0.071
cta concertina 0.069
Su(H) Suppressor of Hairless 0.066
gish gilgamesh 0.065
trc tricornered 0.063
glu gluon 0.063
mbc myoblast city 0.063
shn schnurri 0.061
G-oalpha47A G protein oalpha 47A 0.059
pim pimples 0.057
E(spl) Enhancer of split 0.057
Stat92E Signal-transducer and activator of transcription protein at 92E 0.052
Fs(2)Ket Female sterile (2) Ketel 0.052
ftz-f1 ftz transcription factor 1 0.051
vas vasa 0.051
Lis-1 Lissencephaly-1 0.047
HLHm3 E(spl) region transcript m3 0.047
rap retina aberrant in pattern 0.046
JIL-1 CG6297 gene product from transcript CG6297-RA 0.046
S6k RPS6-p70-protein kinase 0.046
cdc2 CG5363 gene product from transcript CG5363-RA 0.046
tkv thickveins 0.045
Orc2 Origin recognition complex subunit 2 0.045
emc extra macrochaetae 0.041
pita CG3941 gene product from transcript CG3941-RA 0.041
Kr-h1 Kruppel homolog 1 0.040
chb chromosome bows 0.040
Tao-1 CG14217 gene product from transcript CG14217-RF 0.037
hth homothorax 0.036
lat latheo 0.036
l(1)dd4 lethal (1) discs degenerate 4 0.036
ovo CG6824 gene product from transcript CG6824-RE 0.036
Syx1A Syntaxin 1A 0.036
CG9772 CG9772 gene product from transcript CG9772-RB 0.035
so sine oculis 0.035
stil stand still 0.035
Cks85A Cyclin-dependent kinase subunit 85A 0.034
bel belle 0.034
Pvr PDGF- and VEGF-receptor related 0.033
scrib scribbled 0.032
mod(mdg4) modifier of mdg4 0.032
rhi rhino 0.032
DNApol-alpha50 DNA polymerase alpha 50kD 0.031
CG11071 CG11071 gene product from transcript CG11071-RA 0.031
M6 CG7540 gene product from transcript CG7540-RA 0.030
ird5 immune response deficient 5 0.030
esc extra sexcombs 0.030
Taspase1 Taspase 1 0.029
BobA Brother of Bearded A 0.029
sc scute 0.029
Cbl CG7037 gene product from transcript CG7037-RB 0.029
ranshi CG9793 gene product from transcript CG9793-RA 0.029
Vsx2 CG33980 gene product from transcript CG33980-RA 0.028
par-1 CG8201 gene product from transcript CG8201-RA 0.028
Cul-5 Cullin-5 0.028
qua quail 0.027
Imp IGF-II mRNA-binding protein 0.027
cid centromere identifier 0.027
Top1 Topoisomerase 1 0.027
Cdc27 CG8610 gene product from transcript CG8610-RA 0.027
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Homo sapiens
Name Description Probability Func Analog Organism
CDK2 cyclin-dependent kinase 2 1.000
EGFR epidermal growth factor receptor 0.992
TP53 tumor protein p53 0.976
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.968
RB1 retinoblastoma 1 0.966
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.965
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.965
CCND1 cyclin D1 0.897
CCNA2 cyclin A2 0.891
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.887
SKP2 S-phase kinase-associated protein 2 (p45) 0.832
E2F1 E2F transcription factor 1 0.806
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.790
AURKB aurora kinase B 0.783
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.771
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.770
CDK6 cyclin-dependent kinase 6 0.763
RBL1 retinoblastoma-like 1 (p107) 0.757
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.743
NCF1 neutrophil cytosolic factor 1 0.728
EP300 E1A binding protein p300 0.725
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.708
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.700
BRCA1 breast cancer 1, early onset 0.697
GRB10 growth factor receptor-bound protein 10 0.695
CBX5 chromobox homolog 5 0.680
RXRA retinoid X receptor, alpha 0.655
GSK3B glycogen synthase kinase 3 beta 0.627
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.625
CDK1 cyclin-dependent kinase 1 0.624
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.614
E2F7 E2F transcription factor 7 0.596
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.569
CCNB1 cyclin B1 0.555
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.548
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.538
JUP junction plakoglobin 0.534
TAL1 T-cell acute lymphocytic leukemia 1 0.495
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.494
KRT14 keratin 14 0.490
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.489
CCNE1 cyclin E1 0.488
XIAP X-linked inhibitor of apoptosis 0.479
CCNB2 cyclin B2 0.472
MCM7 minichromosome maintenance complex component 7 0.469
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.461
RACGAP1 Rac GTPase activating protein 1 0.447
NOTCH1 notch 1 0.443
PLK1 polo-like kinase 1 0.434
ARHGAP10 Rho GTPase activating protein 10 0.430
E2F8 E2F transcription factor 8 0.428
CDC6 cell division cycle 6 homolog (S. cerevisiae) 0.426
CDT1 chromatin licensing and DNA replication factor 1 0.422
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.419
CKS1B CDC28 protein kinase regulatory subunit 1B 0.417
CDCA8 cell division cycle associated 8 0.382
BIRC5 baculoviral IAP repeat containing 5 0.379
ORC2 origin recognition complex, subunit 2 0.377
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.365
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.361
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.333
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.331
CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.326
CCND3 cyclin D3 0.322
ACTN2 actinin, alpha 2 0.321
SKP1 S-phase kinase-associated protein 1 0.321
FASLG Fas ligand (TNF superfamily, member 6) 0.317
APAF1 apoptotic peptidase activating factor 1 0.312
CDC26 cell division cycle 26 homolog (S. cerevisiae) 0.308
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.308
CAV1 caveolin 1, caveolae protein, 22kDa 0.302
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.299
RAD51C RAD51 homolog C (S. cerevisiae) 0.295
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.292
UBE2C ubiquitin-conjugating enzyme E2C 0.288
PAX3 paired box 3 0.288
C19orf39 chromosome 19 open reading frame 39 0.285
CDKN3 cyclin-dependent kinase inhibitor 3 0.283
CD80 CD80 molecule 0.276
HDAC1 histone deacetylase 1 0.275
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.273
CCR2 chemokine (C-C motif) receptor 2 0.272
CD86 CD86 molecule 0.262
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.254
STAG2 stromal antigen 2 0.245
CCL5 chemokine (C-C motif) ligand 5 0.244
STON2 stonin 2 0.243
CDK9 cyclin-dependent kinase 9 0.239
NRP1 neuropilin 1 0.235
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 0.234
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.234
LIN9 lin-9 homolog (C. elegans) 0.233
FOXM1 forkhead box M1 0.233
SMAD2 SMAD family member 2 0.226
VHL von Hippel-Lindau tumor suppressor 0.223
JAK2 Janus kinase 2 0.219
LRDD leucine-rich repeats and death domain containing 0.219
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.216
TPBG trophoblast glycoprotein 0.215
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.212
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
CLB5 Clb5p 0.314
PFS1 Pfs1p 0.261
ARP8 Arp8p 0.236
RTS1 Rts1p 0.130
CTF4 Ctf4p 0.117
SIN3 Sin3p 0.104
VID24 Vid24p 0.100
CLB2 Clb2p 0.099
GLN3 Gln3p 0.099
CDC28 Cdc28p 0.094
BEM3 Bem3p 0.081
CKS1 Cks1p 0.080
MIG2 Mig2p 0.078
PDS1 Pds1p 0.076
CDH1 Cdh1p 0.075
CDC14 Cdc14p 0.067
TPK1 Tpk1p 0.065
RAD53 Rad53p 0.065
AFT1 Aft1p 0.062
NSE4 Nse4p 0.059
CDC20 Cdc20p 0.059
CDC6 Cdc6p 0.059
HHO1 Hho1p 0.059
GCR2 Gcr2p 0.058
HAL5 Hal5p 0.057
CLB1 Clb1p 0.056
YAK1 Yak1p 0.056
YPL014W hypothetical protein 0.055
APC2 Apc2p 0.050
VHS1 Vhs1p 0.049
CLB3 Clb3p 0.049
PIN4 Pin4p 0.049
CSR2 Csr2p 0.048
PSP2 Psp2p 0.047
MIG3 Mig3p 0.047
ROX1 Rox1p 0.047
SLK19 Slk19p 0.046
YKR075C hypothetical protein 0.046
MMS21 Mms21p 0.046
RAD54 Rad54p 0.046
MAD2 Mad2p 0.045
CDC16 Cdc16p 0.045
CSM1 Csm1p 0.044
PHM8 Phm8p 0.044
NSE1 Nse1p 0.043
HSL1 Hsl1p 0.043
CDC27 Cdc27p 0.043
VPS27 Vps27p 0.042
HXT3 Hxt3p 0.042
CBK1 Cbk1p 0.042
PRP45 Prp45p 0.041
TAO3 Tao3p 0.041
CLB6 Clb6p 0.040
CPR7 Cpr7p 0.040
MIG1 Mig1p 0.039
SAC7 Sac7p 0.038
HSF1 Hsf1p 0.038
RAD55 Rad55p 0.038
KCS1 Kcs1p 0.038
SLD3 Sld3p 0.037
PSF2 Psf2p 0.037
RFC5 Rfc5p 0.037
POG1 Pog1p 0.036
IRA1 Ira1p 0.036
IRC15 Irc15p 0.036
MCM4 Mcm4p 0.035
CDC4 Cdc4p 0.035
YDR506C hypothetical protein 0.034
KRE29 Kre29p 0.033
APC4 Apc4p 0.033
CYR1 Cyr1p 0.033
CDC24 Cdc24p 0.033
SLG1 Slg1p 0.032
YLR297W hypothetical protein 0.032
IES1 Ies1p 0.031
GAT2 Gat2p 0.031
MUS81 Mus81p 0.031
CAM1 Cam1p 0.030
SEC16 Sec16p 0.030
HST3 Hst3p 0.030
FKH2 Fkh2p 0.030
ATG29 Atg29p 0.029
VIK1 Vik1p 0.029
DCC1 Dcc1p 0.029
YKL187C hypothetical protein 0.029
IML1 Iml1p 0.028
CLB4 Clb4p 0.028
ATG2 Atg2p 0.028
CAT8 Cat8p 0.028
TYE7 Tye7p 0.028
CHK1 Chk1p 0.028
YTA7 Yta7p 0.027
VMA4 Vma4p 0.027
NBL1 Nbl1p 0.027
ORC1 Orc1p 0.027
FKH1 Fkh1p 0.026
SWI5 Swi5p 0.026
CTI6 Cti6p 0.026
PBS2 Pbs2p 0.026
RAD7 Rad7p 0.026