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Process View

Drosophila melanogaster

31 genes annotated in fly

cell fate commitment involved in pattern specification

The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell fate commitment involved in pattern specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell fate commitment involved in pattern specification" (in gray)

Name	Description	Probability	Func Analog Organism
E(spl)	Enhancer of split	1.000
HLHm7	E(spl) region transcript m7	0.994	Fly
HLHmgamma	E(spl) region transcript mgamma	0.975	Fly
HLHmdelta	E(spl) region transcript mdelta	0.969	Fly
HLHm5	E(spl) region transcript m5	0.947	Fly
wg	wingless	0.938
N	Notch	0.935
malpha	E(spl) region transcript malpha	0.862	Fly
HLHmbeta	E(spl) region transcript mbeta	0.861	Fly
ato	atonal	0.834
ac	achaete	0.809	Mouse
m4	E(spl) region transcript m4	0.784	Fly
dpp	decapentaplegic	0.693
eyg	eyegone	0.606
hh	hedgehog	0.569
amos	absent MD neurons and olfactory sensilla	0.564
ara	araucan	0.537
H	Hairless	0.477
Tom	Twin of m4	0.434
Dl	Delta	0.400	Human
Su(H)	Suppressor of Hairless	0.398
sca	scabrous	0.326
hth	homothorax	0.321
m2	E(spl) region transcript m2	0.295
Ser	Serrate	0.290
Psn	Presenilin	0.282
en	engrailed	0.280
argos	CG4531 gene product from transcript CG4531-RA	0.280
sens	senseless	0.263
ex	expanded	0.259
pnr	pannier	0.236
brk	brinker	0.221
CtBP	C-terminal Binding Protein	0.220
Traf4	TNF-receptor-associated factor 4	0.207
ro	rough	0.204
esg	escargot	0.203
dally	division abnormally delayed	0.197
sc	scute	0.190	Mouse
Mad	Mothers against dpp	0.185
Tollo	CG6890 gene product from transcript CG6890-RA	0.169
twi	twist	0.165	Fly
ase	asense	0.143	Mouse
bin	biniou	0.142
Antp	Antennapedia	0.137
tkv	thickveins	0.137
Notum	CG13076 gene product from transcript CG13076-RB	0.127
klu	klumpfuss	0.124
emc	extra macrochaetae	0.123
Ubx	Ultrabithorax	0.114
ds	dachsous	0.108
Msi	Male-specific insect derived growth factor	0.105
eg	eagle	0.097
ham	hamlet	0.081
sd	scalloped	0.074
ft	fat	0.073
nub	nubbin	0.072
vg	vestigial	0.071
ush	u-shaped	0.070
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.069
Abd-B	Abdominal B	0.069
HLHm3	E(spl) region transcript m3	0.067	Fly
tup	tailup	0.067
Dll	Distal-less	0.066
shg	shotgun	0.066
sna	snail	0.063
gcm	glial cells missing	0.057
stg	string	0.057
B-H2	BarH2	0.056
sv	shaven	0.056
eya	eyes absent	0.056
dsh	dishevelled	0.054	Worm
m6	E(spl) region transcript m6	0.048
Wnt2	Wnt oncogene analog 2	0.047	Fly
rpr	reaper	0.047
tinc	tincar	0.046
al	aristaless	0.045
ed	echinoid	0.044
pk	prickle	0.042
dy	dusky	0.041
ct	cut	0.041
dco	discs overgrown	0.038
Lim1	CG11354 gene product from transcript CG11354-RA	0.038	Fly
spdo	sanpodo	0.037
org-1	optomotor-blind-related-gene-1	0.037
Poxn	Pox neuro	0.037
tin	tinman	0.036
pan	pangolin	0.036
ab	abrupt	0.036
Fas2	Fasciclin 2	0.035
bib	big brain	0.034
dlg1	discs large 1	0.034
kni	knirps	0.033
gbb	glass bottom boat	0.032
nau	nautilus	0.032
caup	caupolican	0.032	Fly
dac	dachshund	0.030
sog	short gastrulation	0.030
tws	twins	0.030
Cdc42	CG12530 gene product from transcript CG12530-RA	0.030
babo	baboon	0.030
mam	mastermind	0.030
Dip1	Dorsal interacting protein 1	0.029
fz	frizzled	0.029
mys	myospheroid	0.028
Mef2	Myocyte enhancer factor 2	0.028
ems	empty spiracles	0.027
pb	proboscipedia	0.026
beat-Ia	beaten path Ia	0.026
in	inturned	0.026
zfh2	Zn finger homeodomain 2	0.026
Kr	Kruppel	0.025
corto	CG2530 gene product from transcript CG2530-RA	0.025
BobA	Brother of Bearded A	0.024
sns	sticks and stones	0.024
bab2	CG9102 gene product from transcript CG9102-RA	0.023
insc	inscuteable	0.023
Hr39	Hormone receptor-like in 39	0.022
bap	bagpipe	0.022
danr	distal antenna-related	0.021
cp309	CG33957 gene product from transcript CG33957-RB	0.021
ci	cubitus interruptus	0.021	Zebrafish Mouse
toe	twin of eyg	0.021
pll	pelle	0.021
pros	prospero	0.020
olf186-F	CG11430 gene product from transcript CG11430-RB	0.020
os	outstretched	0.020
numb	CG3779 gene product from transcript CG3779-RB	0.020
l(2)gl	lethal (2) giant larvae	0.020
bnl	branchless	0.020
AP-2	CG7807 gene product from transcript CG7807-RB	0.019
Ptp69D	Protein tyrosine phosphatase 69D	0.019
Lim3	CG10699 gene product from transcript CG10699-RB	0.019	Mouse Fly
slou	slouch	0.019
neur	neuralized	0.019
Hand	CG18144 gene product from transcript CG18144-RA	0.018	Fly
csw	corkscrew	0.018
cic	capicua	0.018
btl	breathless	0.018
lab	labial	0.018
tll	tailless	0.018
Ocho	CG3396 gene product from transcript CG3396-RB	0.018
Mrtf	Myocardin-related transcription factor	0.017
Pka-C1	cAMP-dependent protein kinase 1	0.017
CG7536	CG7536 gene product from transcript CG7536-RB	0.017
CG14869	CG14869 gene product from transcript CG14869-RB	0.017
Brd	Bearded	0.017
cpb	capping protein beta	0.017
abd-A	abdominal A	0.017
CG12004	CG12004 gene product from transcript CG12004-RC	0.016
sano	serrano	0.016
CG12496	CG12496 gene product from transcript CG12496-RA	0.016
gro	groucho	0.016
Tehao	CG7121 gene product from transcript CG7121-RA	0.016
fkh	fork head	0.015	Worm
da	daughterless	0.015
noc	no ocelli	0.015
slp1	sloppy paired 1	0.015
rib	ribbon	0.015
ptc	patched	0.015
fred	friend of echinoid	0.015
qm	quemao	0.015
O-fut1	O-fucosyltransferase 1	0.014
hbs	hibris	0.014
zpg	zero population growth	0.014
Tl	Toll	0.014
Dfd	Deformed	0.014
Med	Medea	0.014
vav	CG7893 gene product from transcript CG7893-RB	0.014
tap	target of Poxn	0.014	Fly
kuz	kuzbanian	0.014
wb	wing blister	0.014
dm	diminutive	0.014
pnt	pointed	0.014
Proct	Proctolin	0.013
dpn	deadpan	0.013	Fly
byn	brachyenteron	0.013
Akt1	CG4006 gene product from transcript CG4006-RA	0.013
hkb	huckebein	0.013
stumps	CG31317 gene product from transcript CG31317-RC	0.013
lbl	ladybird late	0.013
CG13424	CG13424 gene product from transcript CG13424-RA	0.013
CG6520	CG6520 gene product from transcript CG6520-RA	0.013
fas	faint sausage	0.013
fj	four-jointed	0.012
erm	earmuff	0.012
how	held out wings	0.012
mxc	multi sex combs	0.012
S	Star	0.012
nct	nicastrin	0.012	Worm
bab1	bric a brac 1	0.012
dan	distal antenna	0.012
nkd	naked cuticle	0.012
ari-1	ariadne	0.012
CG17786	CG17786 gene product from transcript CG17786-RA	0.012
Doc3	Dorsocross3	0.011
CG34139	CG34139 gene product from transcript CG34139-RD	0.011
CG7023	CG7023 gene product from transcript CG7023-RB	0.011
svp	seven up	0.011
cn	cinnabar	0.011
nimC3	nimrod C3	0.011
CG6126	CG6126 gene product from transcript CG6126-RA	0.011
nvy	nervy	0.011
Cpr97Eb	Cuticular protein 97Eb	0.011
rn	rotund	0.011
CG6410	CG6410 gene product from transcript CG6410-RA	0.011
su(f)	suppressor of forked	0.011
lin	lines	0.011
Reck	Reversion-inducing-cysteine-rich protein with kazal motifs	0.011
HtrA2	CG8464 gene product from transcript CG8464-RA	0.011
CG11592	CG11592 gene product from transcript CG11592-RA	0.011
Mob4	CG3403 gene product from transcript CG3403-RA	0.011
Scgdelta	Sarcoglycan delta	0.011
CG13531	CG13531 gene product from transcript CG13531-RB	0.011
Hex-A	Hexokinase A	0.011
tj	traffic jam	0.011
Optix	CG18455 gene product from transcript CG18455-RA	0.011
piwi	CG6122 gene product from transcript CG6122-RA	0.011
Doc2	Dorsocross2	0.010
slmb	supernumerary limbs	0.010
HLH4C	Helix loop helix protein 4C	0.010
dmrt99B	doublesex-Mab related 99B	0.010
CG14193	CG14193 gene product from transcript CG14193-RA	0.010
otk	off-track	0.010
brat	brain tumor	0.010
Cpr50Ca	Cuticular protein 50Ca	0.010
Rpn1	CG7762 gene product from transcript CG7762-RA	0.010
CG31731	CG31731 gene product from transcript CG31731-RB	0.010
ttv	tout-velu	0.010
CG8765	CG8765 gene product from transcript CG8765-RA	0.010
CG32702	CG32702 gene product from transcript CG32702-RB	0.010
toy	twin of eyeless	0.010	Mouse
eff	effete	0.010
CG14168	CG14168 gene product from transcript CG14168-RA	0.010