IMP

Process View

Drosophila melanogaster

30 genes annotated in fly

Multi-species View

melanotic encapsulation of foreign target

GO:0035011

Formation of a multilayered, melanized sheath of cells around a foreign invader.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "melanotic encapsulation of foreign target"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "melanotic encapsulation of foreign target" (in gray)

Name	Description	Probability	Func Analog Organism
proPO-A1	prophenol oxidase A1	1.000
PGRP-LC	Peptidoglycan recognition protein LC	0.996
FucT6	alpha1,6-fucosyltransferase	0.995
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.992
Akt1	CG4006 gene product from transcript CG4006-RA	0.991
alpha-Man-II	alpha Mannosidase II	0.990
Exn	Ephexin	0.988
Hml	Hemolectin	0.985
Flo-2	flotillin 2	0.983
Lsp1alpha	Larval serum protein 1 alpha	0.981	Fly
Shc	SHC-adaptor protein	0.970
Ephrin	CG1862 gene product from transcript CG1862-RA	0.965
Rac1	CG2248 gene product from transcript CG2248-RA	0.963
CG8193	CG8193 gene product from transcript CG8193-RA	0.960
alpha-Man-I	alpha Mannosidase I	0.956
Dhc64C	Dynein heavy chain 64C	0.928
Lsp1beta	Larval serum protein 1 beta	0.921	Fly
Eb1	CG3265 gene product from transcript CG3265-RF	0.896
vav	CG7893 gene product from transcript CG7893-RB	0.894
CG42377	CG42377 gene product from transcript CG42377-RA	0.860
CG11874	CG11874 gene product from transcript CG11874-RA	0.858
CG11376	CG11376 gene product from transcript CG11376-RA	0.847
Rac2	CG8556 gene product from transcript CG8556-RA	0.810
CG7830	CG7830 gene product from transcript CG7830-RA	0.767
dia	diaphanous	0.738
Eph	Eph receptor tyrosine kinase	0.725
Mgat1	UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I	0.691
CG42247	CG42247 gene product from transcript CG42247-RC	0.642
betaInt-nu	beta[nu] integrin	0.511
Cdc42	CG12530 gene product from transcript CG12530-RA	0.406
LanA	Laminin A	0.393
CG6361	CG6361 gene product from transcript CG6361-RA	0.373
gish	gilgamesh	0.358
RhoBTB	CG5701 gene product from transcript CG5701-RA	0.291
CG6370	CG6370 gene product from transcript CG6370-RA	0.266
Sp7	Serine protease 7	0.261
Pten	CG5671 gene product from transcript CG5671-RB	0.259
Obp99b	Odorant-binding protein 99b	0.233
CG13144	CG13144 gene product from transcript CG13144-RA	0.233
scb	scab	0.217
CG33523	CG33523 gene product from transcript CG33523-RD	0.199
RhoL	rho-like	0.197
l(2)gl	lethal (2) giant larvae	0.173
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.166
Lsp2	Larval serum protein 2	0.148	Fly
cact	cactus	0.142
AttA	Attacin-A	0.115
spz	spatzle	0.110
crb	crumbs	0.104
CG13962	CG13962 gene product from transcript CG13962-RA	0.095
NtR	CG6698 gene product from transcript CG6698-RA	0.091
Tl	Toll	0.088
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.083
bsk	basket	0.082
Rho1	CG8416 gene product from transcript CG8416-RB	0.081	Fly
Fbp2	Fat body protein 2	0.073
SPE	Spatzle-Processing Enzyme	0.069
grass	Gram-positive Specific Serine protease	0.066
rok	Rho-kinase	0.065
CG15118	CG15118 gene product from transcript CG15118-RC	0.065
cora	coracle	0.056
Hem	HEM-protein	0.054
MP1	Melanization Protease 1	0.053
nrv2	nervana 2	0.053
Myd88	CG2078 gene product from transcript CG2078-RA	0.052
CG32185	CG32185 gene product from transcript CG32185-RA	0.047
ird1	immune response deficient 1	0.046
Fbp1	Fat body protein 1	0.046	Fly
Spn27A	Serpin 27A	0.045
Spn28D	Serpin 28D	0.045
Cdlc2	Cytoplasmic dynein light chain 2	0.044
Sgs1	Salivary gland secretion 1	0.042
Lcp1	Larval cuticle protein 1	0.042
sina	seven in absentia	0.042
Pvf2	PDGF- and VEGF-related factor 2	0.041
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.039
gl	glass	0.038
GNBP1	Gram-negative bacteria binding protein 1	0.037
fon	fondue	0.036
Shal	Shaker cognate l	0.035
tbce	tubulin-specific chaperone E	0.035
PGRP-SA	Peptidoglycan recognition protein SA	0.035
betaggt-I	beta subunit of type I geranylgeranyl transferase	0.035
l(2)k16918	lethal (2) k16918	0.034
Lsp1gamma	Larval serum protein 1 gamma	0.032	Fly
Sgs4	Salivary gland secretion 4	0.031
ena	enabled	0.031
loqs	loquacious	0.031
alpha-Est5	alpha-Esterase-5	0.031
Irc	Immune-regulated catalase	0.030
G-oalpha47A	G protein oalpha 47A	0.030
Yeti	CG40218 gene product from transcript CG40218-RA	0.029
Mtl	Mig-2-like	0.027	Fly
Sr-CI	Scavenger receptor class C, type I	0.026
Yp3	Yolk protein 3	0.025
Spn77Ba	Serpin 77Ba	0.024
ari-2	ariadne 2	0.024
Est-6	Esterase 6	0.024
CG8501	CG8501 gene product from transcript CG8501-RA	0.024
poly	CG9829 gene product from transcript CG9829-RB	0.023
alpha-Est7	alpha-Esterase-7	0.023
king-tubby	king tubby	0.023
vps2	CG14542 gene product from transcript CG14542-RA	0.023
pcx	pecanex	0.023
CG5111	CG5111 gene product from transcript CG5111-RA	0.023
Vrp1	Verprolin 1	0.022
CG15658	CG15658 gene product from transcript CG15658-RA	0.021
Yp2	Yolk protein 2	0.021
CG31352	CG31352 gene product from transcript CG31352-RA	0.021
CG1021	CG1021 gene product from transcript CG1021-RE	0.021
CG18563	CG18563 gene product from transcript CG18563-RB	0.020
MED26	Mediator complex subunit 26	0.020
CG30288	CG30288 gene product from transcript CG30288-RC	0.020
bip2	CG2009 gene product from transcript CG2009-RA	0.020
IM18	Immune induced molecule 18	0.020
Galpha49B	G protein alpha49B	0.020
CYLD	cylindromatosis	0.020
modSP	modular serine protease	0.020
rempA	reduced mechanoreceptor potential A	0.019
pirk	poor Imd response upon knock-in	0.019
Pvr	PDGF- and VEGF-receptor related	0.019
mbc	myoblast city	0.019
Oli	Olig family	0.019
eater	CG6124 gene product from transcript CG6124-RB	0.018
Dredd	Death related ced-3/Nedd2-like protein	0.018
kst	karst	0.018
repo	reversed polarity	0.018
SNF1A	SNF1A/AMP-activated protein kinase	0.017
Adh	Alcohol dehydrogenase	0.016
nAcRbeta-21C	nicotinic acetylcholine receptor beta 21C	0.016
spirit	Serine Protease Immune Response Integrator	0.016
PGRP-SD	CG7496 gene product from transcript CG7496-RA	0.016
Syx6	Syntaxin 6	0.016
imd	immune deficiency	0.016
CG10631	CG10631 gene product from transcript CG10631-RA	0.016
CG1625	CG1625 gene product from transcript CG1625-RB	0.016
Hr96	Hormone receptor-like in 96	0.016
srp	serpent	0.016
grp	grapes	0.015
CG6385	CG6385 gene product from transcript CG6385-RA	0.015
CG8455	CG8455 gene product from transcript CG8455-RA	0.014
PGRP-LF	Peptidoglycan recognition protein LF	0.014
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.014
CG17082	CG17082 gene product from transcript CG17082-RD	0.014
Drs	Drosomycin	0.014
par-1	CG8201 gene product from transcript CG8201-RA	0.013
loco	locomotion defects	0.013
CG17777	CG17777 gene product from transcript CG17777-RB	0.013
Dlic	Dynein light intermediate chain	0.013
CG1092	CG1092 gene product from transcript CG1092-RA	0.013
Snp	Snipper	0.013
Cyp18a1	Cytochrome P450-18a1	0.012
Gef26	CG9491 gene product from transcript CG9491-RB	0.012
bmm	brummer	0.012
Mrtf	Myocardin-related transcription factor	0.012
garz	gartenzwerg	0.012
CG5999	CG5999 gene product from transcript CG5999-RB	0.012
Yp1	Yolk protein 1	0.012
ird5	immune response deficient 5	0.012
CG3117	CG3117 gene product from transcript CG3117-RB	0.012
CG30148	CG30148 gene product from transcript CG30148-RA	0.012
Dsk	Drosulfakinin	0.011
Xe7	CG2179 gene product from transcript CG2179-RA	0.011
CG9989	CG9989 gene product from transcript CG9989-RA	0.011
alpha-Est2	alpha-Esterase-2	0.011
CG14709	CG14709 gene product from transcript CG14709-RB	0.011
Tsp42Ek	Tetraspanin 42Ek	0.011
CG15369	CG15369 gene product from transcript CG15369-RA	0.011
Ir84a	Ionotropic receptor 84a	0.011
CG14528	CG14528 gene product from transcript CG14528-RA	0.011
Sop2	Suppressor of profilin 2	0.010
Acp62F	Accessory gland peptide 62F	0.010
lkb1	CG9374 gene product from transcript CG9374-RJ	0.010
CG7320	CG7320 gene product from transcript CG7320-RA	0.010	Fly
prom	prominin	0.010
Rheb	CG1081 gene product from transcript CG1081-RA	0.010
Glt	Glutactin	0.010
l(3)mbn	lethal (3) malignant blood neoplasm	0.010
GNBP3	Gram-negative bacteria binding protein 3	0.010
CG10559	CG10559 gene product from transcript CG10559-RB	0.010