IMP

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Homo sapiens

26 genes annotated in human

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regulation of response to oxidative stress

GO:1902882

Any process that modulates the frequency, rate or extent of response to oxidative stress.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of response to oxidative stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of response to oxidative stress" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.902
BCL2L1	BCL2-like 1	0.814	Human
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.586
TRIB3	tribbles homolog 3 (Drosophila)	0.525
EGFR	epidermal growth factor receptor	0.436
PRDX1	peroxiredoxin 1	0.404
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.350
SQSTM1	sequestosome 1	0.314
INSR	insulin receptor	0.281	Worm
BID	BH3 interacting domain death agonist	0.266
GAS6	growth arrest-specific 6	0.262
MAPT	microtubule-associated protein tau	0.206
BCL2	B-cell CLL/lymphoma 2	0.195	Human
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.188
BAK1	BCL2-antagonist/killer 1	0.185	Human
WBP4	WW domain binding protein 4 (formin binding protein 21)	0.175
BAD	BCL2-associated agonist of cell death	0.168
DYNLL1	dynein, light chain, LC8-type 1	0.153
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.152
IRS1	insulin receptor substrate 1	0.137
PML	promyelocytic leukemia	0.137
APOE	apolipoprotein E	0.136
CSNK1A1	casein kinase 1, alpha 1	0.130
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.127
PINK1	PTEN induced putative kinase 1	0.127
FBXO7	F-box protein 7	0.098
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.096
KEAP1	kelch-like ECH-associated protein 1	0.095
BAX	BCL2-associated X protein	0.095	Human
UBE3A	ubiquitin protein ligase E3A	0.093
DDIT3	DNA-damage-inducible transcript 3	0.092
GAB1	GRB2-associated binding protein 1	0.088
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.087
DAXX	death-domain associated protein	0.086
SFPQ	splicing factor proline/glutamine-rich	0.084
BAG3	BCL2-associated athanogene 3	0.078
ZNF746	zinc finger protein 746	0.072
TOP1	topoisomerase (DNA) I	0.066
CRYAB	crystallin, alpha B	0.065
IRS2	insulin receptor substrate 2	0.065
GSK3B	glycogen synthase kinase 3 beta	0.065
NONO	non-POU domain containing, octamer-binding	0.064
VHL	von Hippel-Lindau tumor suppressor	0.061
NAMPT	nicotinamide phosphoribosyltransferase	0.061
RNR2	l-rRNA	0.058
MAP2K5	mitogen-activated protein kinase kinase 5	0.057
ARNT	aryl hydrocarbon receptor nuclear translocator	0.055
HSPB8	heat shock 22kDa protein 8	0.053
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.052
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.052
CPNE6	copine VI (neuronal)	0.051
NCOR2	nuclear receptor corepressor 2	0.051
LOXL1	lysyl oxidase-like 1	0.048
IGF1R	insulin-like growth factor 1 receptor	0.048	Worm
APOA1	apolipoprotein A-I	0.047
SNCAIP	synuclein, alpha interacting protein	0.046
EGLN1	egl nine homolog 1 (C. elegans)	0.045
DUSP1	dual specificity phosphatase 1	0.044
LTBP2	latent transforming growth factor beta binding protein 2	0.044
FTL	ferritin, light polypeptide	0.043
RNF144B	ring finger protein 144B	0.043
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.042
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.042
TGIF1	TGFB-induced factor homeobox 1	0.040
HDAC1	histone deacetylase 1	0.039
GRB10	growth factor receptor-bound protein 10	0.039
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.035
MAP2K6	mitogen-activated protein kinase kinase 6	0.035
PLAU	plasminogen activator, urokinase	0.034	Human
MAPK14	mitogen-activated protein kinase 14	0.033	Fly
PRDX4	peroxiredoxin 4	0.033
CCDC6	coiled-coil domain containing 6	0.032
PDIA4	protein disulfide isomerase family A, member 4	0.032
PLXNB1	plexin B1	0.032
PDIA3	protein disulfide isomerase family A, member 3	0.031
APLP2	amyloid beta (A4) precursor-like protein 2	0.031
HSPA1B	heat shock 70kDa protein 1B	0.030
ERO1L	ERO1-like (S. cerevisiae)	0.030
CALR	calreticulin	0.030
FTH1	ferritin, heavy polypeptide 1	0.029
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.029
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.029
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.028
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.028
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.028	Human
PRKCA	protein kinase C, alpha	0.028
APP	amyloid beta (A4) precursor protein	0.027
RAB5B	RAB5B, member RAS oncogene family	0.026
LRRK2	leucine-rich repeat kinase 2	0.025
GHR	growth hormone receptor	0.025
FAS	Fas (TNF receptor superfamily, member 6)	0.025
MMS22L	MMS22-like, DNA repair protein	0.025
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.024
HM13	histocompatibility (minor) 13	0.024
MEF2C	myocyte enhancer factor 2C	0.024
POLR2C	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	0.024
CUL7	cullin 7	0.023
NOG	noggin	0.023
BANP	BTG3 associated nuclear protein	0.023
SOCS3	suppressor of cytokine signaling 3	0.022
ADRBK1	adrenergic, beta, receptor kinase 1	0.022
PPIB	peptidylprolyl isomerase B (cyclophilin B)	0.022
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.022
CDK2AP2	cyclin-dependent kinase 2 associated protein 2	0.022
LRP6	low density lipoprotein receptor-related protein 6	0.022
AHR	aryl hydrocarbon receptor	0.021
MAX	MYC associated factor X	0.021
LAT	linker for activation of T cells	0.020
CTSD	cathepsin D	0.020
ZBED1	zinc finger, BED-type containing 1	0.020
GAB2	GRB2-associated binding protein 2	0.020
CTSL1	cathepsin L1	0.020
DBN1	drebrin 1	0.020
MAPK6	mitogen-activated protein kinase 6	0.019
NCL	nucleolin	0.019
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.019
HUWE1	HECT, UBA and WWE domain containing 1	0.019
RANBP9	RAN binding protein 9	0.018
KNG1	kininogen 1	0.018
MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	0.018
RIPK2	receptor-interacting serine-threonine kinase 2	0.018
DUSP23	dual specificity phosphatase 23	0.017
CARS	cysteinyl-tRNA synthetase	0.017
DYNLT1	dynein, light chain, Tctex-type 1	0.017
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.017
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.017
JAK2	Janus kinase 2	0.016
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.016
MAP1B	microtubule-associated protein 1B	0.016
TBC1D14	TBC1 domain family, member 14	0.016
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.016
NFIL3	nuclear factor, interleukin 3 regulated	0.016
OBSL1	obscurin-like 1	0.016
EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	0.016
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.016
BIRC3	baculoviral IAP repeat containing 3	0.015
SAT1	spermidine/spermine N1-acetyltransferase 1	0.015
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.015
HSPB2	heat shock 27kDa protein 2	0.015
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.015
PRKCZ	protein kinase C, zeta	0.015
GANAB	glucosidase, alpha; neutral AB	0.015
WASF1	WAS protein family, member 1	0.015
EGLN3	egl nine homolog 3 (C. elegans)	0.015
RUNX1	runt-related transcription factor 1	0.014
ZFYVE9	zinc finger, FYVE domain containing 9	0.014
FUS	fused in sarcoma	0.014
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.014
IL8	interleukin 8	0.014
GCH1	GTP cyclohydrolase 1	0.014
KAT2B	K(lysine) acetyltransferase 2B	0.014
WTAP	Wilms tumor 1 associated protein	0.014
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.014
UBASH3B	ubiquitin associated and SH3 domain containing B	0.014
SDCBP	syndecan binding protein (syntenin)	0.014
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.013
MAPK11	mitogen-activated protein kinase 11	0.013	Fly
PRDX6	peroxiredoxin 6	0.013
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.013
PRDX2	peroxiredoxin 2	0.013
RNF11	ring finger protein 11	0.013
ACSL1	acyl-CoA synthetase long-chain family member 1	0.013
CYLD	cylindromatosis (turban tumor syndrome)	0.013
CMIP	c-Maf-inducing protein	0.013
TIMP2	TIMP metallopeptidase inhibitor 2	0.013
PLAUR	plasminogen activator, urokinase receptor	0.013
HSPA1A	heat shock 70kDa protein 1A	0.013
UBQLN1	ubiquilin 1	0.013
DUSP9	dual specificity phosphatase 9	0.013
WBP2	WW domain binding protein 2	0.012
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.012
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.012
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.012
APLP1	amyloid beta (A4) precursor-like protein 1	0.012
TPPP	tubulin polymerization promoting protein	0.012
NCOA6	nuclear receptor coactivator 6	0.012
CDK12	cyclin-dependent kinase 12	0.012
GFER	growth factor, augmenter of liver regeneration	0.012
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.012
EPAS1	endothelial PAS domain protein 1	0.012	Human
PACRG	PARK2 co-regulated	0.012
ATF5	activating transcription factor 5	0.012	Human
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
ENO1	enolase 1, (alpha)	0.012
CREBBP	CREB binding protein	0.012
VEGFA	vascular endothelial growth factor A	0.011
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.011
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.011
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.011
EZR	ezrin	0.011
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.011
DAPK1	death-associated protein kinase 1	0.011
AR	androgen receptor	0.011
RFWD2	ring finger and WD repeat domain 2	0.011
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.011
CCNE1	cyclin E1	0.011
GRN	granulin	0.011
POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	0.011
RPL11	ribosomal protein L11	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
OTUD4	OTU domain containing 4	0.011
FRS2	fibroblast growth factor receptor substrate 2	0.011
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.011
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.011	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.011
APOC1	apolipoprotein C-I	0.011
CCL20	chemokine (C-C motif) ligand 20	0.011
EPOR	erythropoietin receptor	0.011
ADAM17	ADAM metallopeptidase domain 17	0.011
GTF2I	general transcription factor IIi	0.010
KAT5	K(lysine) acetyltransferase 5	0.010
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.010
CHPF	chondroitin polymerizing factor	0.010
HPR	haptoglobin-related protein	0.010
RAD23B	RAD23 homolog B (S. cerevisiae)	0.010
SFN	stratifin	0.010
SPOP	speckle-type POZ protein	0.010
TERT	telomerase reverse transcriptase	0.010
FHL1	four and a half LIM domains 1	0.010
RARA	retinoic acid receptor, alpha	0.010