IMP

Process View

Homo sapiens

29 genes annotated in human

Multi-species View

protein export from nucleus

GO:0006611

The directed movement of a protein from the nucleus into the cytoplasm.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein export from nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein export from nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.845
STK11	serine/threonine kinase 11	0.728
YAP1	Yes-associated protein 1	0.443
DAXX	death-domain associated protein	0.442
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.435	Human
AXIN1	axin 1	0.389
KPNB1	karyopherin (importin) beta 1	0.341
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.325	Human
NXF1	nuclear RNA export factor 1	0.299
IFI44L	interferon-induced protein 44-like	0.283
SMAD7	SMAD family member 7	0.265
PAX3	paired box 3	0.244
MMS22L	MMS22-like, DNA repair protein	0.218
XPO1	exportin 1 (CRM1 homolog, yeast)	0.213
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.184
AR	androgen receptor	0.132
NUP62	nucleoporin 62kDa	0.124
RCC1	regulator of chromosome condensation 1	0.112
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.102
RAN	RAN, member RAS oncogene family	0.069
WASL	Wiskott-Aldrich syndrome-like	0.068
TNPO1	transportin 1	0.067
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.065
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.063
RANBP9	RAN binding protein 9	0.063
GLIS2	GLIS family zinc finger 2	0.060
NCL	nucleolin	0.057
FBXW11	F-box and WD repeat domain containing 11	0.055
DUSP1	dual specificity phosphatase 1	0.054
SMAD4	SMAD family member 4	0.052
SOD1	superoxide dismutase 1, soluble	0.052
FGFR1	fibroblast growth factor receptor 1	0.051
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.051
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.050
IRF9	interferon regulatory factor 9	0.050
SKP1	S-phase kinase-associated protein 1	0.048
FSTL1	follistatin-like 1	0.047
TGFBR1	transforming growth factor, beta receptor 1	0.047
GHR	growth hormone receptor	0.046
PRDX1	peroxiredoxin 1	0.045
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.044
ZFYVE9	zinc finger, FYVE domain containing 9	0.043
CXXC5	CXXC finger protein 5	0.040
PSIP1	PC4 and SFRS1 interacting protein 1	0.039
ELK1	ELK1, member of ETS oncogene family	0.038
CASP8AP2	caspase 8 associated protein 2	0.038
POU3F2	POU class 3 homeobox 2	0.037
NUP98	nucleoporin 98kDa	0.036
HMGB2	high mobility group box 2	0.036
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.036
ANKRD13A	ankyrin repeat domain 13A	0.036
AXL	AXL receptor tyrosine kinase	0.036
BTRC	beta-transducin repeat containing	0.035
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.035	Human
AKIP1	A kinase (PRKA) interacting protein 1	0.035
BST2	bone marrow stromal cell antigen 2	0.034
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.032
JUP	junction plakoglobin	0.032
RSAD2	radical S-adenosyl methionine domain containing 2	0.031
CTTN	cortactin	0.031
NUP54	nucleoporin 54kDa	0.031
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.030
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.030
ISG15	ISG15 ubiquitin-like modifier	0.030
TCF4	transcription factor 4	0.029
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.029	Human
MAP2K1	mitogen-activated protein kinase kinase 1	0.029
DEDD	death effector domain containing	0.028
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.028
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.027
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.027
MAPT	microtubule-associated protein tau	0.027
STAT1	signal transducer and activator of transcription 1, 91kDa	0.027
PML	promyelocytic leukemia	0.027
EIF4E	eukaryotic translation initiation factor 4E	0.027
IFI44	interferon-induced protein 44	0.026
RYR2	ryanodine receptor 2 (cardiac)	0.026
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.026
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.026
IPO5	importin 5	0.025
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.025
PDPK1	3-phosphoinositide dependent protein kinase-1	0.025
NUP50	nucleoporin 50kDa	0.024
TRIM21	tripartite motif containing 21	0.024
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.024
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.024
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.023
SP100	SP100 nuclear antigen	0.023
ADAR	adenosine deaminase, RNA-specific	0.023
SET	SET nuclear oncogene	0.023
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.023
BCAR1	breast cancer anti-estrogen resistance 1	0.023
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	0.022
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.022
XPO5	exportin 5	0.022
NMI	N-myc (and STAT) interactor	0.021
MAPK1	mitogen-activated protein kinase 1	0.021	Yeast
IFIT5	interferon-induced protein with tetratricopeptide repeats 5	0.021
BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	0.021
RANBP1	RAN binding protein 1	0.021
CABLES1	Cdk5 and Abl enzyme substrate 1	0.021
HIPK2	homeodomain interacting protein kinase 2	0.021
PSEN1	presenilin 1	0.021
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.020
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.020
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.020
SPRR2A	small proline-rich protein 2A	0.020
MAPK9	mitogen-activated protein kinase 9	0.019
IPO13	importin 13	0.019
PDIA3	protein disulfide isomerase family A, member 3	0.019
HMGN2	high mobility group nucleosomal binding domain 2	0.019
WNK1	WNK lysine deficient protein kinase 1	0.018
PLSCR1	phospholipid scramblase 1	0.018
LRP6	low density lipoprotein receptor-related protein 6	0.018
EMD	emerin	0.018
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.017
EGR1	early growth response 1	0.017
DUSP3	dual specificity phosphatase 3	0.017	Yeast
PPIF	peptidylprolyl isomerase F	0.017
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.017
PARP12	poly (ADP-ribose) polymerase family, member 12	0.017
MAPK3	mitogen-activated protein kinase 3	0.017	Yeast
SMAD1	SMAD family member 1	0.016
FBXL15	F-box and leucine-rich repeat protein 15	0.016
ADAM15	ADAM metallopeptidase domain 15	0.016
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.016
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.016
KDM2A	lysine (K)-specific demethylase 2A	0.016
PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	0.016
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.015
IFI16	interferon, gamma-inducible protein 16	0.015
KAT5	K(lysine) acetyltransferase 5	0.015
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.015
HYOU1	hypoxia up-regulated 1	0.015
GOLGA2	golgin A2	0.015
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.015
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.014
PIAS4	protein inhibitor of activated STAT, 4	0.014
ZFPM1	zinc finger protein, multitype 1	0.014
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.014
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.014
NEK1	NIMA (never in mitosis gene a)-related kinase 1	0.014
PTMA	prothymosin, alpha	0.014
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.014
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.014
PPP5C	protein phosphatase 5, catalytic subunit	0.014
SAMD9	sterile alpha motif domain containing 9	0.014
HDAC4	histone deacetylase 4	0.014
FIBP	fibroblast growth factor (acidic) intracellular binding protein	0.014
SENP1	SUMO1/sentrin specific peptidase 1	0.014
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.014
HMGB1	high mobility group box 1	0.013
TPR	translocated promoter region (to activated MET oncogene)	0.013
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.013	Human
MARK2	MAP/microtubule affinity-regulating kinase 2	0.013
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.013
MARCKSL1	MARCKS-like 1	0.013
IFI35	interferon-induced protein 35	0.013
APC	adenomatous polyposis coli	0.013	Worm
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.013
LAP3	leucine aminopeptidase 3	0.013
FTSJD2	FtsJ methyltransferase domain containing 2	0.013
MAPK14	mitogen-activated protein kinase 14	0.013
PEA15	phosphoprotein enriched in astrocytes 15	0.013
ZEB2	zinc finger E-box binding homeobox 2	0.013
TNIK	TRAF2 and NCK interacting kinase	0.013
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.012
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
ERO1L	ERO1-like (S. cerevisiae)	0.012
NUP214	nucleoporin 214kDa	0.012
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.012
ERBB2IP	erbb2 interacting protein	0.012
STRN3	striatin, calmodulin binding protein 3	0.012
MBD1	methyl-CpG binding domain protein 1	0.012
GRB10	growth factor receptor-bound protein 10	0.012
PHF11	PHD finger protein 11	0.012
B2M	beta-2-microglobulin	0.012
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.012
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.012
CBX1	chromobox homolog 1	0.012
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.012
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.012
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.012	Fly
LEF1	lymphoid enhancer-binding factor 1	0.011	Human
PXN	paxillin	0.011
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.011
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.011	Human
VRK2	vaccinia related kinase 2	0.011
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.011
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.011
SALL2	sal-like 2 (Drosophila)	0.011
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.011
LY6E	lymphocyte antigen 6 complex, locus E	0.011
FRS2	fibroblast growth factor receptor substrate 2	0.011
AMOTL1	angiomotin like 1	0.011
IDE	insulin-degrading enzyme	0.011
PPIB	peptidylprolyl isomerase B (cyclophilin B)	0.011
GSK3B	glycogen synthase kinase 3 beta	0.011
SOX7	SRY (sex determining region Y)-box 7	0.011	Human
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.011
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.011
IFIT3	interferon-induced protein with tetratricopeptide repeats 3	0.011
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.011
STIP1	stress-induced-phosphoprotein 1	0.011
HIC1	hypermethylated in cancer 1	0.011
HERC5	hect domain and RLD 5	0.011
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.011
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.011
MYD88	myeloid differentiation primary response gene (88)	0.011
PTEN	phosphatase and tensin homolog	0.011
HPRT1	hypoxanthine phosphoribosyltransferase 1	0.010
RAD23B	RAD23 homolog B (S. cerevisiae)	0.010
TDRD7	tudor domain containing 7	0.010
TP73	tumor protein p73	0.010
RANBP2	RAN binding protein 2	0.010
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.010
PTK7	PTK7 protein tyrosine kinase 7	0.010
UBA2	ubiquitin-like modifier activating enzyme 2	0.010
SAE1	SUMO1 activating enzyme subunit 1	0.010
ALAS1	aminolevulinate, delta-, synthase 1	0.010
CDK6	cyclin-dependent kinase 6	0.010