IMP

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Homo sapiens

32 genes annotated in human

carbohydrate metabolism disease

DOID:0050013

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "carbohydrate metabolism disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "carbohydrate metabolism disease" (in gray)

Name	Description	Probability	Func Analog Organism
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.997
INSR	insulin receptor	0.995
GRB10	growth factor receptor-bound protein 10	0.973
IGF1R	insulin-like growth factor 1 receptor	0.952
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.924
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.863
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.858
IRS2	insulin receptor substrate 2	0.668
MAP2K7	mitogen-activated protein kinase kinase 7	0.634
HNF4A	hepatocyte nuclear factor 4, alpha	0.564
PROX1	prospero homeobox 1	0.520
CD247	CD247 molecule	0.501
STAT5B	signal transducer and activator of transcription 5B	0.405
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.403
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.395
ESRRG	estrogen-related receptor gamma	0.333
PGK1	phosphoglycerate kinase 1	0.324
VAV1	vav 1 guanine nucleotide exchange factor	0.312
IRS1	insulin receptor substrate 1	0.297
GPI	glucose-6-phosphate isomerase	0.289
SH2B1	SH2B adaptor protein 1	0.276
PTBP1	polypyrimidine tract binding protein 1	0.271
PSEN1	presenilin 1	0.251
ALDOA	aldolase A, fructose-bisphosphate	0.231
PLCG1	phospholipase C, gamma 1	0.226
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.209
HNF1A	HNF1 homeobox A	0.208
SREBF2	sterol regulatory element binding transcription factor 2	0.180
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.175
LCK	lymphocyte-specific protein tyrosine kinase	0.155
IL6R	interleukin 6 receptor	0.149
LAT	linker for activation of T cells	0.145
PGAM1	phosphoglycerate mutase 1 (brain)	0.137
MAPK8	mitogen-activated protein kinase 8	0.131
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.111
GCKR	glucokinase (hexokinase 4) regulator	0.110
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.108
JUP	junction plakoglobin	0.106
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.101
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.091
SRCIN1	SRC kinase signaling inhibitor 1	0.083
TKT	transketolase	0.081
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.078
PDX1	pancreatic and duodenal homeobox 1	0.073
HDGF	hepatoma-derived growth factor	0.070
ENO1	enolase 1, (alpha)	0.068
KCNJ11	potassium inwardly-rectifying channel, subfamily J, member 11	0.067
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.065
PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	0.064
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.064
OASL	2'-5'-oligoadenylate synthetase-like	0.054	Human
RECQL5	RecQ protein-like 5	0.053
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.047
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.046
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.046	Human
HNF1B	HNF1 homeobox B	0.045
YBX1	Y box binding protein 1	0.044
HDAC7	histone deacetylase 7	0.044
HIC1	hypermethylated in cancer 1	0.043
TNIK	TRAF2 and NCK interacting kinase	0.043
PTK2	PTK2 protein tyrosine kinase 2	0.042
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.042
SYK	spleen tyrosine kinase	0.042
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.041
SH3RF1	SH3 domain containing ring finger 1	0.040
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.040
HTT	huntingtin	0.039
APOB	apolipoprotein B (including Ag(x) antigen)	0.039
HMGA2	high mobility group AT-hook 2	0.038	Human
CDX2	caudal type homeobox 2	0.034
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.034
STAT5A	signal transducer and activator of transcription 5A	0.033
EMD	emerin	0.033
NKX6-1	NK6 homeobox 1	0.032
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.031
MASP2	mannan-binding lectin serine peptidase 2	0.031
HDAC9	histone deacetylase 9	0.030
PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	0.030
BCR	breakpoint cluster region	0.029
TNK2	tyrosine kinase, non-receptor, 2	0.029
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.029	Human
CARM1	coactivator-associated arginine methyltransferase 1	0.029
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.028
BCAR1	breast cancer anti-estrogen resistance 1	0.027
USP18	ubiquitin specific peptidase 18	0.027
APP	amyloid beta (A4) precursor protein	0.026
SPRR2A	small proline-rich protein 2A	0.026
SOCS3	suppressor of cytokine signaling 3	0.026
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.026
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.025
GRB14	growth factor receptor-bound protein 14	0.025
MTNR1A	melatonin receptor 1A	0.025	Human
NEUROD1	neurogenic differentiation 1	0.025
CAV2	caveolin 2	0.024
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.024
POU2F1	POU class 2 homeobox 1	0.024
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.024
PTPRC	protein tyrosine phosphatase, receptor type, C	0.023
LTK	leukocyte receptor tyrosine kinase	0.023
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.022
PPARG	peroxisome proliferator-activated receptor gamma	0.022
PYY	peptide YY	0.022
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.021	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.021
ONECUT1	one cut homeobox 1	0.021
AR	androgen receptor	0.021
GLIS2	GLIS family zinc finger 2	0.021
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.020	Human
HOXB7	homeobox B7	0.020
PTPRA	protein tyrosine phosphatase, receptor type, A	0.020
PCBP1	poly(rC) binding protein 1	0.020
PRMT6	protein arginine methyltransferase 6	0.020
BST2	bone marrow stromal cell antigen 2	0.020
TCF4	transcription factor 4	0.020
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.020
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.019
ISG15	ISG15 ubiquitin-like modifier	0.019
TRIM14	tripartite motif containing 14	0.019
PKM2	pyruvate kinase, muscle	0.019
ADAM15	ADAM metallopeptidase domain 15	0.019
MUC1	mucin 1, cell surface associated	0.019
APC2	adenomatosis polyposis coli 2	0.019
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.018
CCL20	chemokine (C-C motif) ligand 20	0.018
STAT1	signal transducer and activator of transcription 1, 91kDa	0.018
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.018
FOXA2	forkhead box A2	0.018
EPOR	erythropoietin receptor	0.018
PAX6	paired box 6	0.018	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.017
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.017
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.017
NEUROG3	neurogenin 3	0.017	Human
POU3F4	POU class 3 homeobox 4	0.017
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.017	Human
IFI6	interferon, alpha-inducible protein 6	0.017
CCL14	chemokine (C-C motif) ligand 14	0.017
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.016
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.016
SOCS1	suppressor of cytokine signaling 1	0.016
POFUT1	protein O-fucosyltransferase 1	0.016
JAK2	Janus kinase 2	0.016
SST	somatostatin	0.016
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.016
NKX2-2	NK2 homeobox 2	0.016
HRH1	histamine receptor H1	0.016
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.015
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.015
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.015	Human
CHGA	chromogranin A (parathyroid secretory protein 1)	0.015
GCG	glucagon	0.015
CRX	cone-rod homeobox	0.015
HDAC4	histone deacetylase 4	0.015
GP2	glycoprotein 2 (zymogen granule membrane)	0.015
RUNX1	runt-related transcription factor 1	0.015
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.015
IL8	interleukin 8	0.014
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.014
GJB1	gap junction protein, beta 1, 32kDa	0.014
CAPN1	calpain 1, (mu/I) large subunit	0.014
CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10	0.014
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.014
LBX1	ladybird homeobox 1	0.014
ESRRB	estrogen-related receptor beta	0.014
PTBP2	polypyrimidine tract binding protein 2	0.014
TRPV6	transient receptor potential cation channel, subfamily V, member 6	0.014
SCGN	secretagogin, EF-hand calcium binding protein	0.014
HP	haptoglobin	0.014
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.014
KIF9	kinesin family member 9	0.014
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.014
IKZF4	IKAROS family zinc finger 4 (Eos)	0.014
TRIB1	tribbles homolog 1 (Drosophila)	0.013
MED28	mediator complex subunit 28	0.013
HOXD12	homeobox D12	0.013
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.013
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.013
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.013
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.013
ING2	inhibitor of growth family, member 2	0.013
CTNNBIP1	catenin, beta interacting protein 1	0.013
SLC25A40	solute carrier family 25, member 40	0.013
PNPLA3	patatin-like phospholipase domain containing 3	0.013
FOXO1	forkhead box O1	0.013
RGS20	regulator of G-protein signaling 20	0.013
GYS1	glycogen synthase 1 (muscle)	0.013
RHOB	ras homolog gene family, member B	0.012
RHPN2	rhophilin, Rho GTPase binding protein 2	0.012
SAMD9	sterile alpha motif domain containing 9	0.012
FLNB	filamin B, beta	0.012
ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	0.012
GAB1	GRB2-associated binding protein 1	0.012
GSTCD	glutathione S-transferase, C-terminal domain containing	0.012
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.012
ITIH2	inter-alpha (globulin) inhibitor H2	0.012
PAX4	paired box 4	0.012
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.012
JAK1	Janus kinase 1	0.012
MBD1	methyl-CpG binding domain protein 1	0.012
VIL1	villin 1	0.012
TDRD7	tudor domain containing 7	0.012
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.012
FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	0.012
CTTN	cortactin	0.012
WWTR1	WW domain containing transcription regulator 1	0.012
DTX3L	deltex 3-like (Drosophila)	0.012
USF1	upstream transcription factor 1	0.012
HGFAC	HGF activator	0.012
PPY	pancreatic polypeptide	0.012
TM4SF5	transmembrane 4 L six family member 5	0.012
HK1	hexokinase 1	0.012
EMX1	empty spiracles homeobox 1	0.012
ACTL6B	actin-like 6B	0.012
HIST1H1B	histone cluster 1, H1b	0.012
FOXO3	forkhead box O3	0.012
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.012
CXCL3	chemokine (C-X-C motif) ligand 3	0.012
INPPL1	inositol polyphosphate phosphatase-like 1	0.012
BRSK2	BR serine/threonine kinase 2	0.012
INSM1	insulinoma-associated 1	0.012
HOXA6	homeobox A6	0.012
SAMD4B	sterile alpha motif domain containing 4B	0.012
VAV3	vav 3 guanine nucleotide exchange factor	0.011
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.011
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.011
GUCA2B	guanylate cyclase activator 2B (uroguanylin)	0.011
PAX8	paired box 8	0.011
COX6B1	cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)	0.011
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.011
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.011
TLX2	T-cell leukemia homeobox 2	0.011
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.011
ISL1	ISL LIM homeobox 1	0.011
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.011
PTPRF	protein tyrosine phosphatase, receptor type, F	0.011
EGF	epidermal growth factor	0.011
FGF8	fibroblast growth factor 8 (androgen-induced)	0.011
PAX2	paired box 2	0.011
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.011
APOA1	apolipoprotein A-I	0.011
SOCS2	suppressor of cytokine signaling 2	0.011
RSAD2	radical S-adenosyl methionine domain containing 2	0.011
RBP4	retinol binding protein 4, plasma	0.011
CBX6	chromobox homolog 6	0.011
THEMIS	thymocyte selection associated	0.011
GHR	growth hormone receptor	0.011
TMSB4Y	thymosin beta 4, Y-linked	0.011
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.011
ESR1	estrogen receptor 1	0.011
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.011
CDHR2	cadherin-related family member 2	0.011
MYT1	myelin transcription factor 1	0.011
PABPC1	poly(A) binding protein, cytoplasmic 1	0.011
PDXP	pyridoxal (pyridoxine, vitamin B6) phosphatase	0.011
AQP2	aquaporin 2 (collecting duct)	0.011
STC1	stanniocalcin 1	0.011
REPS2	RALBP1 associated Eps domain containing 2	0.011
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.011
PTPRB	protein tyrosine phosphatase, receptor type, B	0.011
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.011
TLN1	talin 1	0.011
SPRY2	sprouty homolog 2 (Drosophila)	0.010
PA2G4	proliferation-associated 2G4, 38kDa	0.010
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.010
SH2D2A	SH2 domain containing 2A	0.010
RHO	rhodopsin	0.010
PGM1	phosphoglucomutase 1	0.010
TTR	transthyretin	0.010
SERGEF	secretion regulating guanine nucleotide exchange factor	0.010
CYC1	cytochrome c-1	0.010
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.010
TBCD	tubulin folding cofactor D	0.010
ADAR	adenosine deaminase, RNA-specific	0.010
TEAD4	TEA domain family member 4	0.010
KIF1C	kinesin family member 1C	0.010
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.010
CD7	CD7 molecule	0.010
DRD2	dopamine receptor D2	0.010
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.010
CISH	cytokine inducible SH2-containing protein	0.010
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.010
SIAH2	seven in absentia homolog 2 (Drosophila)	0.010
FUS	fused in sarcoma	0.010
RARA	retinoic acid receptor, alpha	0.010
GCGR	glucagon receptor	0.008
HMGA1	high mobility group AT-hook 1	0.007
LIPC	lipase, hepatic	0.007
MTNR1B	melatonin receptor 1B	0.007
IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	0.006
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.005
GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.005
CDKAL1	CDK5 regulatory subunit associated protein 1-like 1	0.005
SLC30A8	solute carrier family 30 (zinc transporter), member 8	0.005
WFS1	Wolfram syndrome 1 (wolframin)	0.005
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.004
GCK	glucokinase (hexokinase 4)	0.004
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.004
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.004
RETN	resistin	0.003
FOXP3	forkhead box P3	0.003
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.002
IL6	interleukin 6 (interferon, beta 2)	0.001
TPI1	triosephosphate isomerase 1	0.001