IMP

Process View

Homo sapiens

3 genes annotated in human

ventricular septum morphogenesis

The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ventricular septum morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ventricular septum morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
JAG1	jagged 1	1.000
SMAD3	SMAD family member 3	0.994
FGF1	fibroblast growth factor 1 (acidic)	0.960
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.803
TBX5	T-box 5	0.786
CXXC5	CXXC finger protein 5	0.643
FGF10	fibroblast growth factor 10	0.629
STK3	serine/threonine kinase 3	0.583
SKIL	SKI-like oncogene	0.536
AXIN1	axin 1	0.521
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.473
DLL1	delta-like 1 (Drosophila)	0.448
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.447
EPAS1	endothelial PAS domain protein 1	0.445
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.408
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.405
JAG2	jagged 2	0.327
GSK3B	glycogen synthase kinase 3 beta	0.325
MAML1	mastermind-like 1 (Drosophila)	0.309
SMAD9	SMAD family member 9	0.306
EP300	E1A binding protein p300	0.299
XIAP	X-linked inhibitor of apoptosis	0.298
CSNK1E	casein kinase 1, epsilon	0.274
NOTCH1	notch 1	0.270
WNT3A	wingless-type MMTV integration site family, member 3A	0.248
RBBP4	retinoblastoma binding protein 4	0.242
SMAD1	SMAD family member 1	0.207
NOTCH2	notch 2	0.188	Human
SOX7	SRY (sex determining region Y)-box 7	0.155
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.137
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.118
FZD1	frizzled homolog 1 (Drosophila)	0.111	Mouse
GATA4	GATA binding protein 4	0.101
FGF7	fibroblast growth factor 7	0.091
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.087
MARCKSL1	MARCKS-like 1	0.082
PAX8	paired box 8	0.081
WNT5A	wingless-type MMTV integration site family, member 5A	0.081	Mouse
EGLN3	egl nine homolog 3 (C. elegans)	0.079
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.077
PIAS4	protein inhibitor of activated STAT, 4	0.075
NOTCH3	notch 3	0.075	Human
CTBP2	C-terminal binding protein 2	0.067
LRRK2	leucine-rich repeat kinase 2	0.066
SIRT1	sirtuin 1	0.064
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.060
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.057
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.056
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.049
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.049
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.048
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.048
LAPTM5	lysosomal protein transmembrane 5	0.048
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.047
STK4	serine/threonine kinase 4	0.046
SEC16A	SEC16 homolog A (S. cerevisiae)	0.045
EGFL7	EGF-like-domain, multiple 7	0.045
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.043
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.040
NOTCH2NL	notch 2 N-terminal like	0.040
SMAD7	SMAD family member 7	0.039	Mouse
EFNB2	ephrin-B2	0.036
TAL1	T-cell acute lymphocytic leukemia 1	0.036
POU3F2	POU class 3 homeobox 2	0.034
KIAA1191	KIAA1191	0.033
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.033
BICD1	bicaudal D homolog 1 (Drosophila)	0.032
MAPK8	mitogen-activated protein kinase 8	0.031
PTK2	PTK2 protein tyrosine kinase 2	0.031
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.030
MCC	mutated in colorectal cancers	0.030
EVC2	Ellis van Creveld syndrome 2	0.030
SOX9	SRY (sex determining region Y)-box 9	0.030
NIN	ninein (GSK3B interacting protein)	0.030
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.029
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.028
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.028
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.027
SNW1	SNW domain containing 1	0.027
FZD7	frizzled homolog 7 (Drosophila)	0.026
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.026
RBPMS	RNA binding protein with multiple splicing	0.026
ARNT	aryl hydrocarbon receptor nuclear translocator	0.026
FAM110C	family with sequence similarity 110, member C	0.025
FBLN1	fibulin 1	0.024
FGFR1	fibroblast growth factor receptor 1	0.024
MAPT	microtubule-associated protein tau	0.024
FAM110A	family with sequence similarity 110, member A	0.024
SNAI1	snail homolog 1 (Drosophila)	0.024
PABPN1	poly(A) binding protein, nuclear 1	0.023
STK38L	serine/threonine kinase 38 like	0.023
TAOK1	TAO kinase 1	0.023
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.023
PDGFC	platelet derived growth factor C	0.022
YAP1	Yes-associated protein 1	0.022
FZD8	frizzled homolog 8 (Drosophila)	0.022
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.022
LMO4	LIM domain only 4	0.022
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.022
TCF4	transcription factor 4	0.022
OCLN	occludin	0.022
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.021
MYOD1	myogenic differentiation 1	0.021
LRP6	low density lipoprotein receptor-related protein 6	0.021	Mouse
CADM4	cell adhesion molecule 4	0.021
CAMSAP1	calmodulin regulated spectrin-associated protein 1	0.020
DLL4	delta-like 4 (Drosophila)	0.020
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.020
CREBBP	CREB binding protein	0.020
HNF4A	hepatocyte nuclear factor 4, alpha	0.020
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.020
SSX4	synovial sarcoma, X breakpoint 4	0.020
FAM83D	family with sequence similarity 83, member D	0.019
FOXC1	forkhead box C1	0.019
SFPQ	splicing factor proline/glutamine-rich	0.019
AMOTL2	angiomotin like 2	0.019
TFPI2	tissue factor pathway inhibitor 2	0.019
EYA2	eyes absent homolog 2 (Drosophila)	0.019
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.019
EED	embryonic ectoderm development	0.019
ACVR1B	activin A receptor, type IB	0.019
NONO	non-POU domain containing, octamer-binding	0.019
DEFA1	defensin, alpha 1	0.019
KDM5B	lysine (K)-specific demethylase 5B	0.019
TGFBR1	transforming growth factor, beta receptor 1	0.019
PER1	period homolog 1 (Drosophila)	0.019
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.018
ACVR1	activin A receptor, type I	0.018
SF1	splicing factor 1	0.017
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.017	Mouse
GATA2	GATA binding protein 2	0.017
FOXA1	forkhead box A1	0.017
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.017
KHSRP	KH-type splicing regulatory protein	0.017
HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase	0.017
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.017
FGF8	fibroblast growth factor 8 (androgen-induced)	0.017
FUS	fused in sarcoma	0.017
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.017
POU3F1	POU class 3 homeobox 1	0.017
FOXO1	forkhead box O1	0.017
ANKRD13A	ankyrin repeat domain 13A	0.016
ZFPM1	zinc finger protein, multitype 1	0.016	Human Mouse
MNX1	motor neuron and pancreas homeobox 1	0.016
MYST2	MYST histone acetyltransferase 2	0.016
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	0.016
ACACA	acetyl-CoA carboxylase alpha	0.016
PCDH17	protocadherin 17	0.016
BBS10	Bardet-Biedl syndrome 10	0.016
FGF2	fibroblast growth factor 2 (basic)	0.016
FOXF2	forkhead box F2	0.016
MAGED1	melanoma antigen family D, 1	0.016
SOX11	SRY (sex determining region Y)-box 11	0.016	Mouse
FOXF1	forkhead box F1	0.016
NID1	nidogen 1	0.016
HES1	hairy and enhancer of split 1, (Drosophila)	0.016	Mouse
SMAD6	SMAD family member 6	0.016
VHL	von Hippel-Lindau tumor suppressor	0.016
HIPK3	homeodomain interacting protein kinase 3	0.015
FGFR3	fibroblast growth factor receptor 3	0.015
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.015
BTG1	B-cell translocation gene 1, anti-proliferative	0.015
TBX1	T-box 1	0.015
ATXN1L	ataxin 1-like	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.015
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.015
FKBP1A	FK506 binding protein 1A, 12kDa	0.015
OTP	orthopedia homeobox	0.015
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.015
NBPF10	neuroblastoma breakpoint family, member 10	0.015
CHSY1	chondroitin sulfate synthase 1	0.015
PAX6	paired box 6	0.015
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.015
SDC2	syndecan 2	0.014
COL2A1	collagen, type II, alpha 1	0.014
DST	dystonin	0.014
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.014
MTMR10	myotubularin related protein 10	0.014
PMEPA1	prostate transmembrane protein, androgen induced 1	0.014
DBN1	drebrin 1	0.014
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.014
FZD2	frizzled homolog 2 (Drosophila)	0.014
SOX5	SRY (sex determining region Y)-box 5	0.014
PLCD3	phospholipase C, delta 3	0.014
TMEM44	transmembrane protein 44	0.014
SLMAP	sarcolemma associated protein	0.013
ODF2	outer dense fiber of sperm tails 2	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
MSX2	msh homeobox 2	0.013
AR	androgen receptor	0.013
CTGF	connective tissue growth factor	0.013
FKBP14	FK506 binding protein 14, 22 kDa	0.013
MDK	midkine (neurite growth-promoting factor 2)	0.013
LBX1	ladybird homeobox 1	0.013
C1QL1	complement component 1, q subcomponent-like 1	0.013
WT1	Wilms tumor 1	0.013
ZNF608	zinc finger protein 608	0.013
MAP2K6	mitogen-activated protein kinase kinase 6	0.013
HOXC6	homeobox C6	0.013
PROX1	prospero homeobox 1	0.013	Mouse
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.013
MSX1	msh homeobox 1	0.013
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.013	Mouse
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.013
CALCR	calcitonin receptor	0.013
ARID1A	AT rich interactive domain 1A (SWI-like)	0.013
NKX6-1	NK6 homeobox 1	0.013
HNF1A	HNF1 homeobox A	0.013
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.013
MKL2	MKL/myocardin-like 2	0.013
COL8A2	collagen, type VIII, alpha 2	0.012
SASH1	SAM and SH3 domain containing 1	0.012
GATA5	GATA binding protein 5	0.012
THAP5	THAP domain containing 5	0.012
MAP1B	microtubule-associated protein 1B	0.012
CCNDBP1	cyclin D-type binding-protein 1	0.012
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.012	Mouse
POU4F1	POU class 4 homeobox 1	0.012
NKX3-2	NK3 homeobox 2	0.012	Human
PTPRF	protein tyrosine phosphatase, receptor type, F	0.012
GATA6	GATA binding protein 6	0.012
COL11A1	collagen, type XI, alpha 1	0.012
FOXD1	forkhead box D1	0.012
SHOX2	short stature homeobox 2	0.012
SIX3	SIX homeobox 3	0.012
FBP1	fructose-1,6-bisphosphatase 1	0.012
JUB	jub, ajuba homolog (Xenopus laevis)	0.012
HOXD3	homeobox D3	0.012
PLK2	polo-like kinase 2	0.012
PDE10A	phosphodiesterase 10A	0.012
POU3F3	POU class 3 homeobox 3	0.012
IRX1	iroquois homeobox 1	0.012
E2F3	E2F transcription factor 3	0.012
ZNF423	zinc finger protein 423	0.012
SALL1	sal-like 1 (Drosophila)	0.012
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.012
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.012
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.012
NPAS1	neuronal PAS domain protein 1	0.012
TBX2	T-box 2	0.012
IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	0.012
HDAC4	histone deacetylase 4	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
PSEN1	presenilin 1	0.012
HOXB7	homeobox B7	0.012
DUSP8	dual specificity phosphatase 8	0.012
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.012
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.012
PKP4	plakophilin 4	0.012
ZNF512B	zinc finger protein 512B	0.012
EDNRB	endothelin receptor type B	0.012
HOXB9	homeobox B9	0.012
GAS1	growth arrest-specific 1	0.011
SIX2	SIX homeobox 2	0.011
ARHGAP29	Rho GTPase activating protein 29	0.011
GPC4	glypican 4	0.011
NCOR1	nuclear receptor corepressor 1	0.011
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.011
LRP4	low density lipoprotein receptor-related protein 4	0.011
ZNF746	zinc finger protein 746	0.011
BMP2	bone morphogenetic protein 2	0.011
F3	coagulation factor III (thromboplastin, tissue factor)	0.011
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.011
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.011
HOXA10	homeobox A10	0.011
EMX2	empty spiracles homeobox 2	0.011
VEGFA	vascular endothelial growth factor A	0.011
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.011
KIAA1543	KIAA1543	0.011
AXIN2	axin 2	0.011
FOXG1	forkhead box G1	0.011
ZNF281	zinc finger protein 281	0.011
HOXD11	homeobox D11	0.011
HP1BP3	heterochromatin protein 1, binding protein 3	0.011
SOX13	SRY (sex determining region Y)-box 13	0.011
AMOTL1	angiomotin like 1	0.011
NEUROG3	neurogenin 3	0.011
ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)	0.011
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.011
ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	0.011
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.011
IRX5	iroquois homeobox 5	0.011
IRS2	insulin receptor substrate 2	0.011
NES	nestin	0.011
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.011
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.011
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.011
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.011
EXPH5	exophilin 5	0.011
NOVA2	neuro-oncological ventral antigen 2	0.011
SFRP5	secreted frizzled-related protein 5	0.011
SOX8	SRY (sex determining region Y)-box 8	0.011
PFN2	profilin 2	0.011
ZFHX4	zinc finger homeobox 4	0.011
LIG3	ligase III, DNA, ATP-dependent	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011	Mouse
MAB21L1	mab-21-like 1 (C. elegans)	0.011
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.011
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.011
UNC45A	unc-45 homolog A (C. elegans)	0.011
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.011
PITX2	paired-like homeodomain 2	0.011	Mouse
GJA1	gap junction protein, alpha 1, 43kDa	0.011
SBK1	SH3-binding domain kinase 1	0.011
MORC4	MORC family CW-type zinc finger 4	0.011
MDC1	mediator of DNA-damage checkpoint 1	0.011
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
LRP1B	low density lipoprotein receptor-related protein 1B	0.011
HOXD13	homeobox D13	0.011
TGFB2	transforming growth factor, beta 2	0.011
VGLL4	vestigial like 4 (Drosophila)	0.011
YY1	YY1 transcription factor	0.011
EPHA4	EPH receptor A4	0.011
INADL	InaD-like (Drosophila)	0.011
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.011
HMX2	H6 family homeobox 2	0.011
TP73	tumor protein p73	0.011
FZD5	frizzled homolog 5 (Drosophila)	0.010
GLUL	glutamate-ammonia ligase	0.010
RNF168	ring finger protein 168	0.010
ADARB1	adenosine deaminase, RNA-specific, B1	0.010
THSD7A	thrombospondin, type I, domain containing 7A	0.010
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.010
ERO1L	ERO1-like (S. cerevisiae)	0.010
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.010
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.010
PDGFA	platelet-derived growth factor alpha polypeptide	0.010
TWIST1	twist homolog 1 (Drosophila)	0.010
VASH2	vasohibin 2	0.010
RAB5B	RAB5B, member RAS oncogene family	0.010
TRIL	TLR4 interactor with leucine-rich repeats	0.010
ENC1	ectodermal-neural cortex 1 (with BTB-like domain)	0.010
GATA3	GATA binding protein 3	0.010
FGD1	FYVE, RhoGEF and PH domain containing 1	0.010
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.010
PIM1	pim-1 oncogene	0.010
FGF3	fibroblast growth factor 3	0.010
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.010
FOXS1	forkhead box S1	0.010
CIR1	corepressor interacting with RBPJ, 1	0.010
TBCD	tubulin folding cofactor D	0.010
SNAI2	snail homolog 2 (Drosophila)	0.010
ZFP106	zinc finger protein 106 homolog (mouse)	0.010
TMEM47	transmembrane protein 47	0.010
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.010
ZNF532	zinc finger protein 532	0.010
HOXA2	homeobox A2	0.010
ACVR2B	activin A receptor, type IIB	0.010
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.010
VLDLR	very low density lipoprotein receptor	0.010
EN1	engrailed homeobox 1	0.010
TLX2	T-cell leukemia homeobox 2	0.010
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.010