IMP

Process View

Homo sapiens

29 genes annotated in human

Multi-species View

vascular process in circulatory system

GO:0003018

A circulatory process that occurs at the level of the vasculature.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vascular process in circulatory system"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vascular process in circulatory system" (in gray)

Name	Description	Probability	Func Analog Organism
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.990
TEK	TEK tyrosine kinase, endothelial	0.961
MPDZ	multiple PDZ domain protein	0.952
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.942
VEGFA	vascular endothelial growth factor A	0.834
FGB	fibrinogen beta chain	0.803
FGA	fibrinogen alpha chain	0.695
ACTN2	actinin, alpha 2	0.674
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.614
AMOT	angiomotin	0.605
YAP1	Yes-associated protein 1	0.593
JAG1	jagged 1	0.489
COTL1	coactosin-like 1 (Dictyostelium)	0.444
NRP1	neuropilin 1	0.438
NAMPT	nicotinamide phosphoribosyltransferase	0.421
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.414
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.397
DRD2	dopamine receptor D2	0.366
TIMP3	TIMP metallopeptidase inhibitor 3	0.315
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.311
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.292
FGG	fibrinogen gamma chain	0.241
PTEN	phosphatase and tensin homolog	0.240
ANGPT2	angiopoietin 2	0.235	Human
A2M	alpha-2-macroglobulin	0.235
IL8	interleukin 8	0.229
MAPK12	mitogen-activated protein kinase 12	0.224
NOTCH1	notch 1	0.215
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.210
NOSTRIN	nitric oxide synthase trafficker	0.208
MAPT	microtubule-associated protein tau	0.199
AMOTL1	angiomotin like 1	0.186	Human
PGF	placental growth factor	0.148	Human
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.146
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.140
PTPRB	protein tyrosine phosphatase, receptor type, B	0.137	Human
NFIL3	nuclear factor, interleukin 3 regulated	0.129
CAV2	caveolin 2	0.127
GCLM	glutamate-cysteine ligase, modifier subunit	0.114
JUP	junction plakoglobin	0.111
VAC14	Vac14 homolog (S. cerevisiae)	0.108
CXCL2	chemokine (C-X-C motif) ligand 2	0.100
CALCRL	calcitonin receptor-like	0.100
LDLR	low density lipoprotein receptor	0.096
DLG4	discs, large homolog 4 (Drosophila)	0.095
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.090
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.088
CRP	C-reactive protein, pentraxin-related	0.088
TIMP2	TIMP metallopeptidase inhibitor 2	0.086
GCLC	glutamate-cysteine ligase, catalytic subunit	0.085
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.083
C19orf10	chromosome 19 open reading frame 10	0.079
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.079	Human
KAT2B	K(lysine) acetyltransferase 2B	0.078
NCOA1	nuclear receptor coactivator 1	0.076
DPYSL4	dihydropyrimidinase-like 4	0.075
RLN3	relaxin 3	0.075
TBC1D10A	TBC1 domain family, member 10A	0.074
THBS1	thrombospondin 1	0.073
THBS2	thrombospondin 2	0.071
COL1A1	collagen, type I, alpha 1	0.065
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.063
STC1	stanniocalcin 1	0.060
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.059
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.058
GJA1	gap junction protein, alpha 1, 43kDa	0.057
IL1B	interleukin 1, beta	0.056
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.056
ADORA2A	adenosine A2a receptor	0.053	Rat
IL6	interleukin 6 (interferon, beta 2)	0.053
VEGFC	vascular endothelial growth factor C	0.050	Human
HP	haptoglobin	0.049
GHR	growth hormone receptor	0.048
CDH5	cadherin 5, type 2 (vascular endothelium)	0.047
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.043
TECPR1	tectonin beta-propeller repeat containing 1	0.043
COL5A1	collagen, type V, alpha 1	0.040
ANGPT1	angiopoietin 1	0.039
COL4A1	collagen, type IV, alpha 1	0.039
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.037
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.036
ADORA1	adenosine A1 receptor	0.035	Rat
CAV1	caveolin 1, caveolae protein, 22kDa	0.035	Mouse
HYOU1	hypoxia up-regulated 1	0.034
GRB7	growth factor receptor-bound protein 7	0.034
LRP1	low density lipoprotein receptor-related protein 1	0.033
FYN	FYN oncogene related to SRC, FGR, YES	0.033
ARNT	aryl hydrocarbon receptor nuclear translocator	0.033
RRAS2	related RAS viral (r-ras) oncogene homolog 2	0.033
FLT4	fms-related tyrosine kinase 4	0.032
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.032
CD93	CD93 molecule	0.031
PKM2	pyruvate kinase, muscle	0.031
JAG2	jagged 2	0.030
COL6A1	collagen, type VI, alpha 1	0.030
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.029
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.029
CCL7	chemokine (C-C motif) ligand 7	0.028
TP73	tumor protein p73	0.028
MAPK8	mitogen-activated protein kinase 8	0.028
PKN1	protein kinase N1	0.027
CUX1	cut-like homeobox 1	0.027
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.027
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.027
ADAM15	ADAM metallopeptidase domain 15	0.027
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.027
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.026
MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.026
AGTR1	angiotensin II receptor, type 1	0.025
EDNRB	endothelin receptor type B	0.025
LAT	linker for activation of T cells	0.023
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.023
SDF2L1	stromal cell-derived factor 2-like 1	0.023
NECAB2	N-terminal EF-hand calcium binding protein 2	0.023
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.023	Rat
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.023
ACVR1	activin A receptor, type I	0.023
CALCA	calcitonin-related polypeptide alpha	0.022
SNAI1	snail homolog 1 (Drosophila)	0.021
ARRDC3	arrestin domain containing 3	0.021
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.021
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.021
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.021
KRT5	keratin 5	0.020
ABI2	abl-interactor 2	0.020
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.020
CTSB	cathepsin B	0.020
PXN	paxillin	0.020
GEM	GTP binding protein overexpressed in skeletal muscle	0.020
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.020
LCK	lymphocyte-specific protein tyrosine kinase	0.020
FRZB	frizzled-related protein	0.019
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.019
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.019
APOA1	apolipoprotein A-I	0.019
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.019
DLL1	delta-like 1 (Drosophila)	0.019
APOC1	apolipoprotein C-I	0.019
BMP4	bone morphogenetic protein 4	0.019
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.018
SAT1	spermidine/spermine N1-acetyltransferase 1	0.018
CYSLTR2	cysteinyl leukotriene receptor 2	0.018
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.018
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.018
PLCG1	phospholipase C, gamma 1	0.018
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.017
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.017
TSHR	thyroid stimulating hormone receptor	0.017
DUSP6	dual specificity phosphatase 6	0.017
PCDH17	protocadherin 17	0.017
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.017
NPPB	natriuretic peptide B	0.017
PLAUR	plasminogen activator, urokinase receptor	0.017
WNT2	wingless-type MMTV integration site family member 2	0.016
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.016
SYK	spleen tyrosine kinase	0.016
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.016
BDKRB2	bradykinin receptor B2	0.016	Human Mouse
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.016
ARRB1	arrestin, beta 1	0.016
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.016
INADL	InaD-like (Drosophila)	0.016
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.016
PEBP4	phosphatidylethanolamine-binding protein 4	0.016
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.016
NF2	neurofibromin 2 (merlin)	0.016
SOD2	superoxide dismutase 2, mitochondrial	0.016	Mouse
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.016
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.016
HSPB1	heat shock 27kDa protein 1	0.016
IGF2	insulin-like growth factor 2 (somatomedin A)	0.016
RBMS3	RNA binding motif, single stranded interacting protein 3	0.016
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.015
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.015
DMD	dystrophin	0.015
DPPA4	developmental pluripotency associated 4	0.015
LAMA4	laminin, alpha 4	0.015
NCOA7	nuclear receptor coactivator 7	0.015
DDR2	discoidin domain receptor tyrosine kinase 2	0.015
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.015
S100A9	S100 calcium binding protein A9	0.015
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.015
F2	coagulation factor II (thrombin)	0.015
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.015
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.014
FGF18	fibroblast growth factor 18	0.014
TBX5	T-box 5	0.014
BCAR1	breast cancer anti-estrogen resistance 1	0.014
EGFL7	EGF-like-domain, multiple 7	0.014
MAP2	microtubule-associated protein 2	0.014
VMP1	vacuole membrane protein 1	0.014
TBXA2R	thromboxane A2 receptor	0.014	Mouse
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.014
COL4A2	collagen, type IV, alpha 2	0.014
PTPRN	protein tyrosine phosphatase, receptor type, N	0.014
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.014	Mouse Rat
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.014
CD34	CD34 molecule	0.014
COL3A1	collagen, type III, alpha 1	0.014
COL2A1	collagen, type II, alpha 1	0.014
PDZK1	PDZ domain containing 1	0.014
GCH1	GTP cyclohydrolase 1	0.013
RIPK2	receptor-interacting serine-threonine kinase 2	0.013
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.013
PLG	plasminogen	0.013
NOTCH4	notch 4	0.013
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.013	Human
MSH4	mutS homolog 4 (E. coli)	0.013
COL18A1	collagen, type XVIII, alpha 1	0.013
GSTM5	glutathione S-transferase mu 5	0.013
NCOA6	nuclear receptor coactivator 6	0.013
GPR116	G protein-coupled receptor 116	0.013
MAPK14	mitogen-activated protein kinase 14	0.013
SH3GL3	SH3-domain GRB2-like 3	0.013
AR	androgen receptor	0.013
NDRG1	N-myc downstream regulated 1	0.013
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.013
PRL	prolactin	0.013
MYH11	myosin, heavy chain 11, smooth muscle	0.012
TAC1	tachykinin, precursor 1	0.012
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.012
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.012
SLIT2	slit homolog 2 (Drosophila)	0.012
FAS	Fas (TNF receptor superfamily, member 6)	0.012
ENG	endoglin	0.012
ACSL1	acyl-CoA synthetase long-chain family member 1	0.012
FYB	FYN binding protein	0.012
THBD	thrombomodulin	0.012
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.012
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.012
DNM1	dynamin 1	0.012
BMP2	bone morphogenetic protein 2	0.012
DLC1	deleted in liver cancer 1	0.012
GPR6	G protein-coupled receptor 6	0.012
CXCR1	chemokine (C-X-C motif) receptor 1	0.012	Rat
IGFBP5	insulin-like growth factor binding protein 5	0.012
WWTR1	WW domain containing transcription regulator 1	0.012
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	0.012	Human
NPY5R	neuropeptide Y receptor Y5	0.012
BIRC3	baculoviral IAP repeat containing 3	0.012
IER3	immediate early response 3	0.012
F2R	coagulation factor II (thrombin) receptor	0.012	Mouse Rat
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.012
AVP	arginine vasopressin	0.012
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.011
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.011
FST	follistatin	0.011
TMEM59L	transmembrane protein 59-like	0.011
COL14A1	collagen, type XIV, alpha 1	0.011
HMOX1	heme oxygenase (decycling) 1	0.011
PTPRR	protein tyrosine phosphatase, receptor type, R	0.011
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.011
NOS3	nitric oxide synthase 3 (endothelial cell)	0.011	Human
INPPL1	inositol polyphosphate phosphatase-like 1	0.011
GUCY1A3	guanylate cyclase 1, soluble, alpha 3	0.011
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.011
SH3GL1	SH3-domain GRB2-like 1	0.011
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.011
RELN	reelin	0.011
SPARCL1	SPARC-like 1 (hevin)	0.011
LRRC32	leucine rich repeat containing 32	0.011
PGM5	phosphoglucomutase 5	0.011
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.011
CFP	complement factor properdin	0.011
PTPRC	protein tyrosine phosphatase, receptor type, C	0.011
FZD4	frizzled homolog 4 (Drosophila)	0.011
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.011
ND1	NADH dehydrogenase, subunit 1 (complex I)	0.011
FLNA	filamin A, alpha	0.011
AHSG	alpha-2-HS-glycoprotein	0.011
SOX17	SRY (sex determining region Y)-box 17	0.011
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.011
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.011
FOXF1	forkhead box F1	0.011
CD4	CD4 molecule	0.011
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.011
PURA	purine-rich element binding protein A	0.011
SPRR2A	small proline-rich protein 2A	0.011
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.011
AXL	AXL receptor tyrosine kinase	0.011
ITGA8	integrin, alpha 8	0.011
IGF1	insulin-like growth factor 1 (somatomedin C)	0.011
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.011
ENPEP	glutamyl aminopeptidase (aminopeptidase A)	0.011
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.010
SMAD7	SMAD family member 7	0.010
CCL3	chemokine (C-C motif) ligand 3	0.010
DPYS	dihydropyrimidinase	0.010
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.010
RGS4	regulator of G-protein signaling 4	0.010
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.010
SLIT3	slit homolog 3 (Drosophila)	0.010	Human
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.010
ANGPTL4	angiopoietin-like 4	0.010	Human
ADM	adrenomedullin	0.010
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.010
CXCL5	chemokine (C-X-C motif) ligand 5	0.010
ITIH2	inter-alpha (globulin) inhibitor H2	0.010
CTNND1	catenin (cadherin-associated protein), delta 1	0.010
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.010
PROCR	protein C receptor, endothelial	0.010
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.010
SORBS1	sorbin and SH3 domain containing 1	0.010
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.010
GPR50	G protein-coupled receptor 50	0.010
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.010	Human
ADRA2B	adrenergic, alpha-2B-, receptor	0.010
DCTN1	dynactin 1	0.010
EGLN3	egl nine homolog 3 (C. elegans)	0.010
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.010	Human
EFNA2	ephrin-A2	0.010
MCAM	melanoma cell adhesion molecule	0.010
RGS2	regulator of G-protein signaling 2, 24kDa	0.010	Mouse