IMP

Process View

Homo sapiens

40 genes annotated in human

glycerophospholipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glycerophospholipid biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glycerophospholipid biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.997	Rat
FGFR1	fibroblast growth factor receptor 1	0.837
FGFR2	fibroblast growth factor receptor 2	0.813
GRB2	growth factor receptor-bound protein 2	0.642
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.532
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.480
MPDZ	multiple PDZ domain protein	0.456
VEGFA	vascular endothelial growth factor A	0.375	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.369
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.248
ALB	albumin	0.246
IRS1	insulin receptor substrate 1	0.213
APOA1	apolipoprotein A-I	0.184
GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	0.179	Yeast
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.152
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.143
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.143
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.137
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.114
NRP1	neuropilin 1	0.114
A2M	alpha-2-macroglobulin	0.103
HP	haptoglobin	0.098
PIGT	phosphatidylinositol glycan anchor biosynthesis, class T	0.083	Yeast
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.081
CHMP2B	chromatin modifying protein 2B	0.075
SYK	spleen tyrosine kinase	0.072
NOS1	nitric oxide synthase 1 (neuronal)	0.068
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.067
PLCG1	phospholipase C, gamma 1	0.063	Human
CMIP	c-Maf-inducing protein	0.053
APOC1	apolipoprotein C-I	0.053
APOC3	apolipoprotein C-III	0.046
UVRAG	UV radiation resistance associated gene	0.045
CD63	CD63 molecule	0.044
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.043
SH3BP2	SH3-domain binding protein 2	0.042
BLNK	B-cell linker	0.041
CUTA	cutA divalent cation tolerance homolog (E. coli)	0.040
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.039
PGF	placental growth factor	0.038	Human
SOS1	son of sevenless homolog 1 (Drosophila)	0.038
GAB1	GRB2-associated binding protein 1	0.038
BECN1	beclin 1, autophagy related	0.036
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.035
LCAT	lecithin-cholesterol acyltransferase	0.035
FGF10	fibroblast growth factor 10	0.034	Human
EGFR	epidermal growth factor receptor	0.031
AXL	AXL receptor tyrosine kinase	0.031
SPAG9	sperm associated antigen 9	0.031
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.030
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.029
SAR1B	SAR1 homolog B (S. cerevisiae)	0.029
FGF7	fibroblast growth factor 7	0.029	Human Rat
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.028
FGF1	fibroblast growth factor 1 (acidic)	0.028	Human
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.028
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.027
SLMO2	slowmo homolog 2 (Drosophila)	0.027	Yeast
MDFI	MyoD family inhibitor	0.026
C17orf28	chromosome 17 open reading frame 28	0.026
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.026
PIKFYVE	phosphoinositide kinase, FYVE finger containing	0.026
SORBS1	sorbin and SH3 domain containing 1	0.026
SORBS3	sorbin and SH3 domain containing 3	0.026
NME4	non-metastatic cells 4, protein expressed in	0.026
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.026
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.025
APOC2	apolipoprotein C-II	0.025
TLR3	toll-like receptor 3	0.024
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.024
GRB7	growth factor receptor-bound protein 7	0.024
PTPRB	protein tyrosine phosphatase, receptor type, B	0.024
RABGGTB	Rab geranylgeranyltransferase, beta subunit	0.024
INO80B	INO80 complex subunit B	0.024
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.024
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.023	Mouse
GAB2	GRB2-associated binding protein 2	0.023
DCTN1	dynactin 1	0.023
TSPAN4	tetraspanin 4	0.023
GRB10	growth factor receptor-bound protein 10	0.022
C6orf211	chromosome 6 open reading frame 211	0.022
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.021	Human Fly
FGA	fibrinogen alpha chain	0.021
VAV2	vav 2 guanine nucleotide exchange factor	0.021
IPO11	importin 11	0.021
PIGS	phosphatidylinositol glycan anchor biosynthesis, class S	0.021	Yeast
GMFB	glia maturation factor, beta	0.020
LMF2	lipase maturation factor 2	0.020
TMEM41B	transmembrane protein 41B	0.020
SH2B1	SH2B adaptor protein 1	0.020
VAV3	vav 3 guanine nucleotide exchange factor	0.019
CD28	CD28 molecule	0.019
APOA2	apolipoprotein A-II	0.019
ERRFI1	ERBB receptor feedback inhibitor 1	0.019
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.019	Mouse Rat
LIN7C	lin-7 homolog C (C. elegans)	0.019
SSTR3	somatostatin receptor 3	0.018
WDTC1	WD and tetratricopeptide repeats 1	0.018
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.018
TTR	transthyretin	0.018
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.018
PDGFC	platelet derived growth factor C	0.018
ATMIN	ATM interactor	0.018
APRT	adenine phosphoribosyltransferase	0.018
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.018
INSR	insulin receptor	0.018
GANAB	glucosidase, alpha; neutral AB	0.017
HPS6	Hermansky-Pudlak syndrome 6	0.017
PDGFA	platelet-derived growth factor alpha polypeptide	0.017
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
NUCB1	nucleobindin 1	0.017
LYPLA1	lysophospholipase I	0.017
AHSG	alpha-2-HS-glycoprotein	0.017
CHD1	chromodomain helicase DNA binding protein 1	0.016
MFN1	mitofusin 1	0.016
CHUK	conserved helix-loop-helix ubiquitous kinase	0.016
ERGIC2	ERGIC and golgi 2	0.016
ABI1	abl-interactor 1	0.016
PLTP	phospholipid transfer protein	0.016
SH2D3A	SH2 domain containing 3A	0.016
ALAS1	aminolevulinate, delta-, synthase 1	0.016
VAT1	vesicle amine transport protein 1 homolog (T. californica)	0.016
EZR	ezrin	0.016
FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	0.016	Yeast
MAN1B1	mannosidase, alpha, class 1B, member 1	0.015
HSPA13	heat shock protein 70kDa family, member 13	0.015
GFAP	glial fibrillary acidic protein	0.015
SNAI1	snail homolog 1 (Drosophila)	0.015
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.015
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.015
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.015
KCTD9	potassium channel tetramerisation domain containing 9	0.015
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.015
TMEM33	transmembrane protein 33	0.015
IGSF8	immunoglobulin superfamily, member 8	0.015
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.015
SCARB1	scavenger receptor class B, member 1	0.015
UBASH3B	ubiquitin associated and SH3 domain containing B	0.015
ADAM15	ADAM metallopeptidase domain 15	0.015
TNS4	tensin 4	0.015
TFG	TRK-fused gene	0.015
SLC35A3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	0.015
MESDC2	mesoderm development candidate 2	0.015
PHRF1	PHD and ring finger domains 1	0.015
PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.015
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.014
CLPTM1L	CLPTM1-like	0.014
AKAP2	A kinase (PRKA) anchor protein 2	0.014
NLRX1	NLR family member X1	0.014
DOK4	docking protein 4	0.014
PTK6	PTK6 protein tyrosine kinase 6	0.014
PANK3	pantothenate kinase 3	0.014
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.014
PFDN4	prefoldin subunit 4	0.014
RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.014
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.014	Human Mouse Rat Fly
GOLT1B	golgi transport 1B	0.014
PFKL	phosphofructokinase, liver	0.014
TMED5	transmembrane emp24 protein transport domain containing 5	0.014
TMEM38B	transmembrane protein 38B	0.014
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.014
ACSL3	acyl-CoA synthetase long-chain family member 3	0.013
C20orf24	chromosome 20 open reading frame 24	0.013
LRP1	low density lipoprotein receptor-related protein 1	0.013
TNS3	tensin 3	0.013
ARRDC3	arrestin domain containing 3	0.013
PYROXD1	pyridine nucleotide-disulphide oxidoreductase domain 1	0.013
CD151	CD151 molecule (Raph blood group)	0.013
EIF6	eukaryotic translation initiation factor 6	0.013
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.013
DSE	dermatan sulfate epimerase	0.013
PNPLA2	patatin-like phospholipase domain containing 2	0.013
DSCAML1	Down syndrome cell adhesion molecule like 1	0.013
CHMP5	chromatin modifying protein 5	0.013
B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	0.013
LTBP3	latent transforming growth factor beta binding protein 3	0.013
ARRB1	arrestin, beta 1	0.013
COL2A1	collagen, type II, alpha 1	0.013
IRS2	insulin receptor substrate 2	0.013
AZIN1	antizyme inhibitor 1	0.013
ALG3	asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)	0.013
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.012
APOB	apolipoprotein B (including Ag(x) antigen)	0.012
SLC25A32	solute carrier family 25, member 32	0.012
PDCD10	programmed cell death 10	0.012
IFRD1	interferon-related developmental regulator 1	0.012
LAT	linker for activation of T cells	0.012
TSTA3	tissue specific transplantation antigen P35B	0.012
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.012
ITFG3	integrin alpha FG-GAP repeat containing 3	0.012
APBB3	amyloid beta (A4) precursor protein-binding, family B, member 3	0.012
CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.012
GRAP2	GRB2-related adaptor protein 2	0.012
TP53BP1	tumor protein p53 binding protein 1	0.012
CCDC91	coiled-coil domain containing 91	0.012
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.012
XPOT	exportin, tRNA (nuclear export receptor for tRNAs)	0.012
SEP15	15 kDa selenoprotein	0.012
NAMPT	nicotinamide phosphoribosyltransferase	0.012
VAV1	vav 1 guanine nucleotide exchange factor	0.012
PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	0.012
TMEM123	transmembrane protein 123	0.012
BAI1	brain-specific angiogenesis inhibitor 1	0.012
CST3	cystatin C	0.012
THBS1	thrombospondin 1	0.012
C1D	C1D nuclear receptor corepressor	0.012
EML3	echinoderm microtubule associated protein like 3	0.012
SMC1A	structural maintenance of chromosomes 1A	0.012
C1orf27	chromosome 1 open reading frame 27	0.012
NRG1	neuregulin 1	0.011
NUPL1	nucleoporin like 1	0.011
AKAP12	A kinase (PRKA) anchor protein 12	0.011
GAA	glucosidase, alpha; acid	0.011
USP33	ubiquitin specific peptidase 33	0.011
GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
PKN3	protein kinase N3	0.011
RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.011
NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	0.011
ACTR1B	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	0.011
KRT9	keratin 9	0.011
FAM134A	family with sequence similarity 134, member A	0.011
TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	0.011
EGF	epidermal growth factor	0.011
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.011
DGAT1	diacylglycerol O-acyltransferase 1	0.011
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.011
AQP7	aquaporin 7	0.011
GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1	0.011
MUC1	mucin 1, cell surface associated	0.011
CHID1	chitinase domain containing 1	0.011
NECAB3	N-terminal EF-hand calcium binding protein 3	0.011
NOS3	nitric oxide synthase 3 (endothelial cell)	0.011
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	0.011
NR1D1	nuclear receptor subfamily 1, group D, member 1	0.011
AP2A2	adaptor-related protein complex 2, alpha 2 subunit	0.011
KLHL24	kelch-like 24 (Drosophila)	0.011
TFPI2	tissue factor pathway inhibitor 2	0.011
FGFR3	fibroblast growth factor receptor 3	0.011
SKIL	SKI-like oncogene	0.011
YIPF6	Yip1 domain family, member 6	0.011
SMN2	survival of motor neuron 2, centromeric	0.011
UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.011
BZW1	basic leucine zipper and W2 domains 1	0.011
ACSL1	acyl-CoA synthetase long-chain family member 1	0.011
NME3	non-metastatic cells 3, protein expressed in	0.011
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.011
BLK	B lymphoid tyrosine kinase	0.010
DAPK1	death-associated protein kinase 1	0.010
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.010
LDLR	low density lipoprotein receptor	0.010
HSPG2	heparan sulfate proteoglycan 2	0.010
SCOC	short coiled-coil protein	0.010
CCNC	cyclin C	0.010
CD99	CD99 molecule	0.010
NRBF2	nuclear receptor binding factor 2	0.010
MINPP1	multiple inositol-polyphosphate phosphatase 1	0.010
GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	0.010
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.010
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.010
UFM1	ubiquitin-fold modifier 1	0.010
PTGFRN	prostaglandin F2 receptor negative regulator	0.010
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.010
NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	0.010
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.010
GCLM	glutamate-cysteine ligase, modifier subunit	0.010
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.010
SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)	0.010
AHCTF1	AT hook containing transcription factor 1	0.010
C9orf82	chromosome 9 open reading frame 82	0.010
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.010
DCTN2	dynactin 2 (p50)	0.010
CCL14	chemokine (C-C motif) ligand 14	0.010
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.010