IMP

Process View

Mus musculus

18 genes annotated in mouse

secondary metabolic process

GO:0019748

The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "secondary metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "secondary metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Tyr	tyrosinase	0.999
Lyst	lysosomal trafficking regulator	0.998
Mitf	microphthalmia-associated transcription factor	0.985
Tyrp1	tyrosinase-related protein 1	0.982
Rac1	RAS-related C3 botulinum substrate 1	0.842	Fly
Casp1	caspase 1	0.792	Fly
Oca2	oculocutaneous albinism II	0.750
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.748	Mouse
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.690
Mc1r	melanocortin 1 receptor	0.687
a	nonagouti	0.641
Kit	kit oncogene	0.639
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.611	Fly
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.570
Gbp5	guanylate binding protein 5	0.555
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.472
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.463
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.449
Bax	BCL2-associated X protein	0.440	Mouse
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.387
Bcl2	B-cell leukemia/lymphoma 2	0.369
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.368	Fly
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.344
Otc	ornithine transcarbamylase	0.286
Pycard	PYD and CARD domain containing	0.267
Aadac	arylacetamide deacetylase (esterase)	0.265
Tlr4	toll-like receptor 4	0.225
Ctnnb1	catenin (cadherin associated protein), beta 1	0.225
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.223
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.207
Slc26a4	solute carrier family 26, member 4	0.204
Vav2	vav 2 oncogene	0.194	Fly
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.189
Efnb2	ephrin B2	0.188
Akr1c6	aldo-keto reductase family 1, member C6	0.170	Human
Cps1	carbamoyl-phosphate synthetase 1	0.169
Grb2	growth factor receptor bound protein 2	0.169
Arhgap1	Rho GTPase activating protein 1	0.166
Trp53	transformation related protein 53	0.162
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.155
Fmo5	flavin containing monooxygenase 5	0.140
Pomc	pro-opiomelanocortin-alpha	0.138
Gata4	GATA binding protein 4	0.138
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.137
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.132	Rat
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.129
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.127
Ephb2	Eph receptor B2	0.125	Fly
Aim2	absent in melanoma 2	0.124
Pou2af1	POU domain, class 2, associating factor 1	0.123
Vav3	vav 3 oncogene	0.116	Fly
Inhbc	inhibin beta-C	0.115
Slc45a2	solute carrier family 45, member 2	0.108
Il7	interleukin 7	0.107
Pmel	premelanosome protein	0.106
Mlph	melanophilin	0.105
Pgk1	phosphoglycerate kinase 1	0.104
Bak1	BCL2-antagonist/killer 1	0.103	Mouse
Lepr	leptin receptor	0.098
Cxcl13	chemokine (C-X-C motif) ligand 13	0.088
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.088	Rat
Gsta2	glutathione S-transferase, alpha 2 (Yc2)	0.087
Shc3	src homology 2 domain-containing transforming protein C3	0.086	Fly
Myo5a	myosin VA	0.086
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.084
Efnb1	ephrin B1	0.082
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.080
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.079	Rat
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.079
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.076
Cdsn	corneodesmosin	0.075
Hrg	histidine-rich glycoprotein	0.069
Lta	lymphotoxin A	0.068	Fly
Rdh7	retinol dehydrogenase 7	0.068
Cbl	Casitas B-lineage lymphoma	0.066
F13b	coagulation factor XIII, beta subunit	0.066
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.065
Gsta4	glutathione S-transferase, alpha 4	0.065	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.062
Chga	chromogranin A	0.055
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.055
Msn	moesin	0.053
Tdo2	tryptophan 2,3-dioxygenase	0.053
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.052
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.052
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.051	Fly
Slc24a5	solute carrier family 24, member 5	0.051
Adra2b	adrenergic receptor, alpha 2b	0.051
Plcg1	phospholipase C, gamma 1	0.050
Ces1d	carboxylesterase 1D	0.049
Eda	ectodysplasin-A	0.049
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.049
Cd19	CD19 antigen	0.048
Vav1	vav 1 oncogene	0.048	Fly
Aqp8	aquaporin 8	0.047
Alb	albumin	0.047
Il18	interleukin 18	0.046
Mbl2	mannose-binding lectin (protein C) 2	0.045
Ikbkb	inhibitor of kappaB kinase beta	0.045
Il4	interleukin 4	0.045
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.044
Camk4	calcium/calmodulin-dependent protein kinase IV	0.044
Inmt	indolethylamine N-methyltransferase	0.041
Ephb3	Eph receptor B3	0.040	Fly
F9	coagulation factor IX	0.039
Kcnu1	potassium channel, subfamily U, member 1	0.038
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.037
Rab38	RAB38, member of RAS oncogene family	0.037
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.037
Jag1	jagged 1	0.037
Psen1	presenilin 1	0.037
Klc1	kinesin light chain 1	0.036
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.035
Id2	inhibitor of DNA binding 2	0.035
Tox	thymocyte selection-associated high mobility group box	0.035
Sult1d1	sulfotransferase family 1D, member 1	0.034
Wnt7b	wingless-related MMTV integration site 7B	0.034
Nf1	neurofibromatosis 1	0.034
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.034
Tnf	tumor necrosis factor	0.034	Fly
Src	Rous sarcoma oncogene	0.034
Ikzf3	IKAROS family zinc finger 3	0.033
Ldlr	low density lipoprotein receptor	0.033
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.032
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.032
Kitl	kit ligand	0.032
Barx2	BarH-like homeobox 2	0.032
BC021891	cDNA sequence BC021891	0.032
Star	steroidogenic acute regulatory protein	0.031
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.030
Ces3a	carboxylesterase 3A	0.029
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.029	Fly
Gdnf	glial cell line derived neurotrophic factor	0.029
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.028
Pon1	paraoxonase 1	0.028
Npy1r	neuropeptide Y receptor Y1	0.028
Adh1	alcohol dehydrogenase 1 (class I)	0.028
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.028
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.027
Mup3	major urinary protein 3	0.027
Rhoa	ras homolog gene family, member A	0.027	Fly
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.027
Fbn2	fibrillin 2	0.027
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.027
Ednrb	endothelin receptor type B	0.026
Lep	leptin	0.026
Mtpn	myotrophin	0.026
Ces1c	carboxylesterase 1C	0.026
Spi16	serine protease inhibitor 16	0.026
Bcl6	B-cell leukemia/lymphoma 6	0.025
Iqgap1	IQ motif containing GTPase activating protein 1	0.025
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.025
Apoh	apolipoprotein H	0.025
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.025
Itga3	integrin alpha 3	0.025
Prox1	prospero-related homeobox 1	0.024
Adam10	a disintegrin and metallopeptidase domain 10	0.024
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.024
Afm	afamin	0.024
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.023
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.023
Dpep1	dipeptidase 1 (renal)	0.022
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.022
Ctnnd1	catenin (cadherin associated protein), delta 1	0.022
Bmp4	bone morphogenetic protein 4	0.022
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.022
Lrrk1	leucine-rich repeat kinase 1	0.022
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.022
Mapk10	mitogen-activated protein kinase 10	0.022	Fly
Mapk8	mitogen-activated protein kinase 8	0.021	Fly
Mapk9	mitogen-activated protein kinase 9	0.021	Fly
Sardh	sarcosine dehydrogenase	0.021
Per2	period homolog 2 (Drosophila)	0.021
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.021
Hmox1	heme oxygenase (decycling) 1	0.021
Il10	interleukin 10	0.020
Ptk6	PTK6 protein tyrosine kinase 6	0.020
Gstm3	glutathione S-transferase, mu 3	0.020
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.020	Rat
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.020
Bnc1	basonuclin 1	0.020
Vdr	vitamin D receptor	0.019
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.019
Tmpo	thymopoietin	0.019
G6pc	glucose-6-phosphatase, catalytic	0.019
Cxcr5	chemokine (C-X-C motif) receptor 5	0.019
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.019
Gstm1	glutathione S-transferase, mu 1	0.019
Atf2	activating transcription factor 2	0.019
Krt1	keratin 1	0.018
Nat1	N-acetyl transferase 1	0.018
Ltb	lymphotoxin B	0.018
C9	complement component 9	0.018
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.018
Pparg	peroxisome proliferator activated receptor gamma	0.018
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.018
Ces1g	carboxylesterase 1G	0.018
Reln	reelin	0.017
Mapk14	mitogen-activated protein kinase 14	0.017
L1cam	L1 cell adhesion molecule	0.017
Apoc4	apolipoprotein C-IV	0.017
Macf1	microtubule-actin crosslinking factor 1	0.017
Sult1b1	sulfotransferase family 1B, member 1	0.017
Vegfa	vascular endothelial growth factor A	0.017
Wnt6	wingless-related MMTV integration site 6	0.017
Sykb	spleen tyrosine kinase	0.017
Azgp1	alpha-2-glycoprotein 1, zinc	0.017
Bhmt	betaine-homocysteine methyltransferase	0.017
Ccdc88a	coiled coil domain containing 88A	0.017
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.016
Epha4	Eph receptor A4	0.016	Fly
Chn1	chimerin (chimaerin) 1	0.016
Egln1	EGL nine homolog 1 (C. elegans)	0.016
Rab27a	RAB27A, member RAS oncogene family	0.016
Dct	dopachrome tautomerase	0.016
Zeb1	zinc finger E-box binding homeobox 1	0.016
Gata6	GATA binding protein 6	0.016
Plxna3	plexin A3	0.016
Slc12a1	solute carrier family 12, member 1	0.016
Zp1	zona pellucida glycoprotein 1	0.016
H2-M9	histocompatibility 2, M region locus 9	0.016
Shc2	SHC (Src homology 2 domain containing) transforming protein 2	0.015	Fly
Rnd3	Rho family GTPase 3	0.015
Upp2	uridine phosphorylase 2	0.015
Mug1	murinoglobulin 1	0.015
Hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.015	Rat
Ugt3a1	UDP glycosyltransferases 3 family, polypeptide A1	0.015
Rbp4	retinol binding protein 4, plasma	0.015
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.015
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.015
Apoc1	apolipoprotein C-I	0.015
Cd14	CD14 antigen	0.015
Ikbkg	inhibitor of kappaB kinase gamma	0.015
Clrn3	clarin 3	0.015
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.014
Keg1	kidney expressed gene 1	0.014
Cbfb	core binding factor beta	0.014
Spnb3	spectrin beta 3	0.014
Acly	ATP citrate lyase	0.014
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.014
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.014
Gsta3	glutathione S-transferase, alpha 3	0.014
2810422J05Rik	RIKEN cDNA 2810422J05 gene	0.014
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.014
Ctnna2	catenin (cadherin associated protein), alpha 2	0.014
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.014	Human
Spry4	sprouty homolog 4 (Drosophila)	0.014
Pah	phenylalanine hydroxylase	0.014	Worm
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.014
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.014
Il17re	interleukin 17 receptor E	0.014
Aox1	aldehyde oxidase 1	0.014
Fasn	fatty acid synthase	0.014
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.014
Cfhr1	complement factor H-related 1	0.013
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.013
Soat1	sterol O-acyltransferase 1	0.013
Mertk	c-mer proto-oncogene tyrosine kinase	0.013
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.013
Cdhr5	cadherin-related family member 5	0.013
Cd22	CD22 antigen	0.013
Cd3e	CD3 antigen, epsilon polypeptide	0.013
Ces2e	carboxylesterase 2E	0.013
Mocs1	molybdenum cofactor synthesis 1	0.013
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.013
Nrg3	neuregulin 3	0.013
Il1b	interleukin 1 beta	0.013
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.013
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.013
Sh3rf1	SH3 domain containing ring finger 1	0.013
Osmr	oncostatin M receptor	0.013
Lamc1	laminin, gamma 1	0.013
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.013	Rat
Vsig4	V-set and immunoglobulin domain containing 4	0.012
Klkb1	kallikrein B, plasma 1	0.012
Odf1	outer dense fiber of sperm tails 1	0.012
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.012
Dmgdh	dimethylglycine dehydrogenase precursor	0.012
Il3	interleukin 3	0.012
Cfh	complement component factor h	0.012
Ptprv	protein tyrosine phosphatase, receptor type, V	0.012
Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	0.012
Gpr12	G-protein coupled receptor 12	0.012
Cbr1	carbonyl reductase 1	0.012
Apoa5	apolipoprotein A-V	0.012
S100a3	S100 calcium binding protein A3	0.012
Gab1	growth factor receptor bound protein 2-associated protein 1	0.012
Pdcd1	programmed cell death 1	0.012
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.012
Inhba	inhibin beta-A	0.012
Gm14743	predicted gene 14743	0.011
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.011
Efnb3	ephrin B3	0.011
Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	0.011
Ptprd	protein tyrosine phosphatase, receptor type, D	0.011
Rora	RAR-related orphan receptor alpha	0.011
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.011
Ppy	pancreatic polypeptide	0.011
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.011
Akr1c21	aldo-keto reductase family 1, member C21	0.011	Human
Dock1	dedicator of cytokinesis 1	0.011
Dio1	deiodinase, iodothyronine, type I	0.011
Ifna9	interferon alpha 9	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Gstt1	glutathione S-transferase, theta 1	0.011
Sim1	single-minded homolog 1 (Drosophila)	0.011
Bid	BH3 interacting domain death agonist	0.011
Ptafr	platelet-activating factor receptor	0.011
Aicda	activation-induced cytidine deaminase	0.011
Tnks1bp1	tankyrase 1 binding protein 1	0.011
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.010
Slc2a5	solute carrier family 2 (facilitated glucose transporter), member 5	0.010
Gripap1	GRIP1 associated protein 1	0.010
Acsm1	acyl-CoA synthetase medium-chain family member 1	0.010
Hao2	hydroxyacid oxidase 2	0.010
Ahsg	alpha-2-HS-glycoprotein	0.010
Mat1a	methionine adenosyltransferase I, alpha	0.010
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.010
Lrrk2	leucine-rich repeat kinase 2	0.010
Mfn2	mitofusin 2	0.010
Uox	urate oxidase	0.010
Krt2	keratin 2	0.010
Chrm5	cholinergic receptor, muscarinic 5	0.010
Prkce	protein kinase C, epsilon	0.010