IMP

Process View

Mus musculus

19 genes annotated in mouse

negative regulation of growth of symbiont involved in interaction with host

Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of growth of symbiont involved in interaction with host"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of growth of symbiont involved in interaction with host" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.984
Fasl	Fas ligand (TNF superfamily, member 6)	0.977	Mouse
Tlr4	toll-like receptor 4	0.918	Mouse
Lta	lymphotoxin A	0.839
Il10	interleukin 10	0.815
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.707
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.689
Cd44	CD44 antigen	0.658
Apoe	apolipoprotein E	0.656
Cd40	CD40 antigen	0.547
Ldlr	low density lipoprotein receptor	0.474
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.409
Ccl4	chemokine (C-C motif) ligand 4	0.376
Mpo	myeloperoxidase	0.371
Nos2	nitric oxide synthase 2, inducible	0.369
Elane	elastase, neutrophil expressed	0.312
Myd88	myeloid differentiation primary response gene 88	0.297
Ctsg	cathepsin G	0.295
Cma1	chymase 1, mast cell	0.292	Mouse
Ticam1	toll-like receptor adaptor molecule 1	0.271
Cxcr5	chemokine (C-X-C motif) receptor 5	0.260
Unc93b1	unc-93 homolog B1 (C. elegans)	0.244
Pdcd1	programmed cell death 1	0.233
Ngp	neutrophilic granule protein	0.230	Mouse
Camp	cathelicidin antimicrobial peptide	0.226
Ltf	lactotransferrin	0.210
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.204
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.166
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.163
Ifnar2	interferon (alpha and beta) receptor 2	0.151
Ccr2	chemokine (C-C motif) receptor 2	0.150
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.148
Mmp9	matrix metallopeptidase 9	0.146
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.145
Pou2af1	POU domain, class 2, associating factor 1	0.142
Mcpt8	mast cell protease 8	0.134	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.129
Mmp8	matrix metallopeptidase 8	0.128
Cxcl13	chemokine (C-X-C motif) ligand 13	0.127
Il4	interleukin 4	0.121
Xcl1	chemokine (C motif) ligand 1	0.120
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.113
Il1r1	interleukin 1 receptor, type I	0.101
Ncr1	natural cytotoxicity triggering receptor 1	0.098
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.096
Il12rb1	interleukin 12 receptor, beta 1	0.095
Lyz2	lysozyme 2	0.094
Oas3	2'-5' oligoadenylate synthetase 3	0.093
Gbp1	guanylate binding protein 1	0.083
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.082	Mouse
Il7	interleukin 7	0.081
Prg2	proteoglycan 2, bone marrow	0.081
Irg1	immunoresponsive gene 1	0.079
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.079
Cd19	CD19 antigen	0.078
Cd7	CD7 antigen	0.077
Stat2	signal transducer and activator of transcription 2	0.077
Rhd	Rh blood group, D antigen	0.075
Il2rb	interleukin 2 receptor, beta chain	0.074
Cpa3	carboxypeptidase A3, mast cell	0.074
Cst7	cystatin F (leukocystatin)	0.072
Duox2	dual oxidase 2	0.072
Ltb	lymphotoxin B	0.068
Jak3	Janus kinase 3	0.065
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.064
Itgal	integrin alpha L	0.064
Gp1ba	glycoprotein 1b, alpha polypeptide	0.064
Vdr	vitamin D receptor	0.063
Ifng	interferon gamma	0.062
Il22	interleukin 22	0.060	Mouse
Batf	basic leucine zipper transcription factor, ATF-like	0.057
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.055
Il1b	interleukin 1 beta	0.055
Slpi	secretory leukocyte peptidase inhibitor	0.054
Gfi1b	growth factor independent 1B	0.053
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.052
Tbx21	T-box 21	0.050
Nlrp3	NLR family, pyrin domain containing 3	0.050	Mouse
Ooep	oocyte expressed protein homolog (dog)	0.049
Gzmb	granzyme B	0.047	Mouse
Casp1	caspase 1	0.047
Dsg4	desmoglein 4	0.047
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.046
Ubd	ubiquitin D	0.045
Klf1	Kruppel-like factor 1 (erythroid)	0.045
Esr1	estrogen receptor 1 (alpha)	0.044
Cxcl10	chemokine (C-X-C motif) ligand 10	0.042
Irak1	interleukin-1 receptor-associated kinase 1	0.042
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.041
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.041
Trem3	triggering receptor expressed on myeloid cells 3	0.040
Tlr2	toll-like receptor 2	0.040
Sfrp4	secreted frizzled-related protein 4	0.039
Lyl1	lymphoblastomic leukemia 1	0.038
Nkg7	natural killer cell group 7 sequence	0.038
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.038
Aoah	acyloxyacyl hydrolase	0.037
Prf1	perforin 1 (pore forming protein)	0.037
Lipc	lipase, hepatic	0.036
Gzmd	granzyme D	0.036	Mouse
Tshr	thyroid stimulating hormone receptor	0.036
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.036
Spna1	spectrin alpha 1	0.036
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.036
Trim10	tripartite motif-containing 10	0.036
Btk	Bruton agammaglobulinemia tyrosine kinase	0.035
Rsad2	radical S-adenosyl methionine domain containing 2	0.034
Sh2d2a	SH2 domain protein 2A	0.034
Tspo2	translocator protein 2	0.033
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.033
Col14a1	collagen, type XIV, alpha 1	0.033
Socs1	suppressor of cytokine signaling 1	0.033
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.033
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.032
Blk	B lymphoid kinase	0.032
Slc12a6	solute carrier family 12, member 6	0.032
Folr2	folate receptor 2 (fetal)	0.032
H2-M9	histocompatibility 2, M region locus 9	0.030
Prtn3	proteinase 3	0.030	Mouse
Naip6	NLR family, apoptosis inhibitory protein 6	0.029
Lag3	lymphocyte-activation gene 3	0.029
Sftpd	surfactant associated protein D	0.029	Mouse
C3	complement component 3	0.029
Cd300ld	CD300 molecule-like family member d	0.029
Fpr1	formyl peptide receptor 1	0.028
Tpsb2	tryptase beta 2	0.028
Gypa	glycophorin A	0.027
Prg3	proteoglycan 3	0.027
Fcna	ficolin A	0.027
Butr1	butyrophilin related 1	0.027
Ifnar1	interferon (alpha and beta) receptor 1	0.026
Il17a	interleukin 17A	0.026
Icos	inducible T-cell co-stimulator	0.026
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.025
Sva	seminal vesicle antigen	0.024
Il10ra	interleukin 10 receptor, alpha	0.024
Irak4	interleukin-1 receptor-associated kinase 4	0.024
Ermap	erythroblast membrane-associated protein	0.024
Mcpt2	mast cell protease 2	0.024	Mouse
Mitf	microphthalmia-associated transcription factor	0.024
Cd96	CD96 antigen	0.023
Il23a	interleukin 23, alpha subunit p19	0.023
Slfn4	schlafen 4	0.023
Gba	glucosidase, beta, acid	0.023
Il18rap	interleukin 18 receptor accessory protein	0.023
Cd40lg	CD40 ligand	0.023	Mouse
Hemgn	hemogen	0.023
Spp1	secreted phosphoprotein 1	0.023
Rhag	Rhesus blood group-associated A glycoprotein	0.022
Tal1	T-cell acute lymphocytic leukemia 1	0.022
Il18r1	interleukin 18 receptor 1	0.022
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.022
Slfn1	schlafen 1	0.022
Soat2	sterol O-acyltransferase 2	0.022
Dpt	dermatopontin	0.021
Prss2	protease, serine, 2	0.021
Clnk	cytokine-dependent hematopoietic cell linker	0.021
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.021
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.020
C2	complement component 2 (within H-2S)	0.020
Vpreb3	pre-B lymphocyte gene 3	0.020
Marco	macrophage receptor with collagenous structure	0.020
Naip1	NLR family, apoptosis inhibitory protein 1	0.020
Il1r2	interleukin 1 receptor, type II	0.020
Ccl22	chemokine (C-C motif) ligand 22	0.020
Fcnb	ficolin B	0.020
Xcr1	chemokine (C motif) receptor 1	0.020
Mefv	Mediterranean fever	0.020
Itgb2l	integrin beta 2-like	0.019
Ctse	cathepsin E	0.019
Pycard	PYD and CARD domain containing	0.019
Tg	thyroglobulin	0.019
Gpr35	G protein-coupled receptor 35	0.019
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.019	Mouse
Slamf7	SLAM family member 7	0.019
Fcgr1	Fc receptor, IgG, high affinity I	0.019
Il1f9	interleukin 1 family, member 9	0.018
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.018
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.018
Crtam	cytotoxic and regulatory T cell molecule	0.018
Cd177	CD177 antigen	0.018
Cd5l	CD5 antigen-like	0.018
Ctsw	cathepsin W	0.017
Pdcd1lg2	programmed cell death 1 ligand 2	0.017
Irf1	interferon regulatory factor 1	0.017	Mouse
Ifitm6	interferon induced transmembrane protein 6	0.017
Gfi1	growth factor independent 1	0.017
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.017
Kel	Kell blood group	0.016
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.016
Col1a1	collagen, type I, alpha 1	0.016
Cxcl9	chemokine (C-X-C motif) ligand 9	0.016
Myh2	myosin, heavy polypeptide 2, skeletal muscle, adult	0.016
Ly6i	lymphocyte antigen 6 complex, locus I	0.016
Mt4	metallothionein 4	0.016
Cd14	CD14 antigen	0.016
Adam8	a disintegrin and metallopeptidase domain 8	0.016
Il3	interleukin 3	0.016
Prl2b1	prolactin family 2, subfamily b, member 1	0.016
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.016
Alox15	arachidonate 15-lipoxygenase	0.015
Gzmk	granzyme K	0.015	Mouse
Itga2b	integrin alpha 2b	0.015
Gna15	guanine nucleotide binding protein, alpha 15	0.015
Gzmc	granzyme C	0.015	Mouse
Trim21	tripartite motif-containing 21	0.015
Ticam2	toll-like receptor adaptor molecule 2	0.015
Irf4	interferon regulatory factor 4	0.015	Mouse
Il1rn	interleukin 1 receptor antagonist	0.015
Il6	interleukin 6	0.015
Miox	myo-inositol oxygenase	0.015
Bcl6	B-cell leukemia/lymphoma 6	0.015
Il1a	interleukin 1 alpha	0.014
Acly	ATP citrate lyase	0.014
Car1	carbonic anhydrase 1	0.014
Samhd1	SAM domain and HD domain, 1	0.014
Ggt5	gamma-glutamyltransferase 5	0.014
Inhbc	inhibin beta-C	0.014
Nfe2	nuclear factor, erythroid derived 2	0.014
Slamf8	SLAM family member 8	0.014
Gzmf	granzyme F	0.014	Mouse
Cidec	cell death-inducing DFFA-like effector c	0.014
Ang2	angiogenin, ribonuclease A family, member 2	0.013
Napsa	napsin A aspartic peptidase	0.013
Mgmt	O-6-methylguanine-DNA methyltransferase	0.013
Adamdec1	ADAM-like, decysin 1	0.013
Wfdc12	WAP four-disulfide core domain 12	0.013
Sfpi1	SFFV proviral integration 1	0.013
Igtp	interferon gamma induced GTPase	0.013
Fabp4	fatty acid binding protein 4, adipocyte	0.013
Mcpt4	mast cell protease 4	0.013	Mouse
Itgax	integrin alpha X	0.013
Ccr3	chemokine (C-C motif) receptor 3	0.013
Gpr133	G protein-coupled receptor 133	0.012
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.012
Mcl1	myeloid cell leukemia sequence 1	0.012
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.012
Uba7	ubiquitin-like modifier activating enzyme 7	0.012
Ccl3	chemokine (C-C motif) ligand 3	0.012
Gpr97	G protein-coupled receptor 97	0.012
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.012
Cd160	CD160 antigen	0.012
Pgk2	phosphoglycerate kinase 2	0.012
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.012
Lcn4	lipocalin 4	0.012
Cblb	Casitas B-lineage lymphoma b	0.012
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.012
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.012
Aim2	absent in melanoma 2	0.011
Uts2r	urotensin 2 receptor	0.011
Siglece	sialic acid binding Ig-like lectin E	0.011
Cldn13	claudin 13	0.011
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.011
Rac1	RAS-related C3 botulinum substrate 1	0.011
Gpr182	G protein-coupled receptor 182	0.011
Gp9	glycoprotein 9 (platelet)	0.011
Il2ra	interleukin 2 receptor, alpha chain	0.011
Cd33	CD33 antigen	0.011
Cd79b	CD79B antigen	0.011
Agxt	alanine-glyoxylate aminotransferase	0.011
Igk	immunoglobulin kappa chain complex	0.011
Aqp9	aquaporin 9	0.011
Epx	eosinophil peroxidase	0.011	Mouse
Gjb2	gap junction protein, beta 2	0.011
Ccl5	chemokine (C-C motif) ligand 5	0.011
Aicda	activation-induced cytidine deaminase	0.011
Cxcr3	chemokine (C-X-C motif) receptor 3	0.011
Fasn	fatty acid synthase	0.011
Gzme	granzyme E	0.011	Mouse
Icam4	intercellular adhesion molecule 4, Landsteiner-Wiener blood group	0.010
Il15	interleukin 15	0.010
Mup4	major urinary protein 4	0.010
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.010
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.010
Oosp1	oocyte secreted protein 1	0.010
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.010