IMP

Process View

Mus musculus

12 genes annotated in mouse

Multi-species View

defense response to fungus

GO:0050832

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "defense response to fungus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "defense response to fungus" (in gray)

Name	Description	Probability	Func Analog Organism
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.992
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.989	Fly
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.986	Fly
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.961
Tnf	tumor necrosis factor	0.814
Tgfbr2	transforming growth factor, beta receptor II	0.735
En1	engrailed 1	0.514	Fly
Clec4d	C-type lectin domain family 4, member d	0.462	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.456	Fly
Gdf5	growth differentiation factor 5	0.415	Worm
Il1rn	interleukin 1 receptor antagonist	0.384
Ctsg	cathepsin G	0.368
Tlr4	toll-like receptor 4	0.347
Elane	elastase, neutrophil expressed	0.343
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.313
Mapk14	mitogen-activated protein kinase 14	0.300	Fly
Ptgs2	prostaglandin-endoperoxide synthase 2	0.271
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.263
Msr1	macrophage scavenger receptor 1	0.213
Lyz2	lysozyme 2	0.185
Ifng	interferon gamma	0.182
Il2rg	interleukin 2 receptor, gamma chain	0.181
Tshr	thyroid stimulating hormone receptor	0.170
Clec4e	C-type lectin domain family 4, member e	0.148	Mouse
Myd88	myeloid differentiation primary response gene 88	0.136	Fly
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.134
Ncr1	natural cytotoxicity triggering receptor 1	0.133
C5ar1	complement component 5a receptor 1	0.133
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.125
Junb	Jun-B oncogene	0.122
Ccr1	chemokine (C-C motif) receptor 1	0.119
Msx2	homeobox, msh-like 2	0.117
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.114
Bicd2	bicaudal D homolog 2 (Drosophila)	0.092
Cd44	CD44 antigen	0.085
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.083
Stat3	signal transducer and activator of transcription 3	0.079
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.079
Casp1	caspase 1	0.077
Il1b	interleukin 1 beta	0.075
Retn	resistin	0.074
Tlr2	toll-like receptor 2	0.070
Ccl24	chemokine (C-C motif) ligand 24	0.069
Cd209d	CD209d antigen	0.068	Mouse
Ngp	neutrophilic granule protein	0.065
Cd209b	CD209b antigen	0.059	Mouse
Fmn1	formin 1	0.055
Il10ra	interleukin 10 receptor, alpha	0.054
Socs1	suppressor of cytokine signaling 1	0.053
Cxcl1	chemokine (C-X-C motif) ligand 1	0.051
Il1r1	interleukin 1 receptor, type I	0.050
Ltb	lymphotoxin B	0.050
Cidec	cell death-inducing DFFA-like effector c	0.049
Pycard	PYD and CARD domain containing	0.048
Slpi	secretory leukocyte peptidase inhibitor	0.048
Prg2	proteoglycan 2, bone marrow	0.047
Ccl3	chemokine (C-C motif) ligand 3	0.045
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.044
Il6	interleukin 6	0.043
Selp	selectin, platelet	0.043
Prol1	proline rich, lacrimal 1	0.042
Smad4	MAD homolog 4 (Drosophila)	0.041
Ccl4	chemokine (C-C motif) ligand 4	0.041
Cpa3	carboxypeptidase A3, mast cell	0.040
Fcna	ficolin A	0.040
Jarid2	jumonji, AT rich interactive domain 2	0.039
Cma1	chymase 1, mast cell	0.039	Mouse
Ccl22	chemokine (C-C motif) ligand 22	0.038
Batf	basic leucine zipper transcription factor, ATF-like	0.038
Ccl2	chemokine (C-C motif) ligand 2	0.038
Cd19	CD19 antigen	0.037
Ccdc64	coiled-coil domain containing 64	0.037
Gzmf	granzyme F	0.036	Mouse
Ticam1	toll-like receptor adaptor molecule 1	0.036
Mapk11	mitogen-activated protein kinase 11	0.036	Fly
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.036
Tbxas1	thromboxane A synthase 1, platelet	0.035
Niacr1	niacin receptor 1	0.035
Ooep	oocyte expressed protein homolog (dog)	0.035
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.034
Tnip1	TNFAIP3 interacting protein 1	0.034
Alox15	arachidonate 15-lipoxygenase	0.034
Il1r2	interleukin 1 receptor, type II	0.033
Gdf3	growth differentiation factor 3	0.032
Runx1	runt related transcription factor 1	0.032
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.031
Unc93b1	unc-93 homolog B1 (C. elegans)	0.030
Ang2	angiogenin, ribonuclease A family, member 2	0.030
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.030
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.030
Duox2	dual oxidase 2	0.030	Zebrafish
Cd209f	CD209f antigen	0.028
Bcl3	B-cell leukemia/lymphoma 3	0.028	Fly
Cxcl2	chemokine (C-X-C motif) ligand 2	0.028	Mouse
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.028
Il9r	interleukin 9 receptor	0.028
Xcl1	chemokine (C motif) ligand 1	0.027
Mefv	Mediterranean fever	0.027
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.026
Cd14	CD14 antigen	0.026
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.026
Il2rb	interleukin 2 receptor, beta chain	0.026
Mcpt2	mast cell protease 2	0.026	Mouse
Mapkapk2	MAP kinase-activated protein kinase 2	0.026
Has1	hyaluronan synthase1	0.026
Myf6	myogenic factor 6	0.026
Fpr2	formyl peptide receptor 2	0.025
Irf1	interferon regulatory factor 1	0.024
Cd3e	CD3 antigen, epsilon polypeptide	0.024
Camp	cathelicidin antimicrobial peptide	0.024
Slamf8	SLAM family member 8	0.024
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.024
Il12b	interleukin 12b	0.023
Il4ra	interleukin 4 receptor, alpha	0.023
Gzmb	granzyme B	0.022	Mouse
Adam8	a disintegrin and metallopeptidase domain 8	0.022
Ccr7	chemokine (C-C motif) receptor 7	0.022
Ccl6	chemokine (C-C motif) ligand 6	0.022
Gp5	glycoprotein 5 (platelet)	0.022
Fpr1	formyl peptide receptor 1	0.022
Eng	endoglin	0.021
Rhog	ras homolog gene family, member G	0.021
Cd209g	CD209g antigen	0.021
Lin28a	lin-28 homolog A (C. elegans)	0.021
Hp	haptoglobin	0.021
Sykb	spleen tyrosine kinase	0.021
Dnase1l3	deoxyribonuclease 1-like 3	0.020
Ccr6	chemokine (C-C motif) receptor 6	0.020
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.020
Ubd	ubiquitin D	0.020
Ciita	class II transactivator	0.020
Chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.020
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
Mcpt4	mast cell protease 4	0.020	Mouse
Sparc	secreted acidic cysteine rich glycoprotein	0.020
Gcet2	germinal center expressed transcript 2	0.020
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.020
Atf2	activating transcription factor 2	0.020
Il18rap	interleukin 18 receptor accessory protein	0.020
Ptgir	prostaglandin I receptor (IP)	0.019
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.019
Ptk2	PTK2 protein tyrosine kinase 2	0.019
Fas	Fas (TNF receptor superfamily member 6)	0.019
Cxcl13	chemokine (C-X-C motif) ligand 13	0.019
Cxcr5	chemokine (C-X-C motif) receptor 5	0.018
Card9	caspase recruitment domain family, member 9	0.018
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.018
Abi1	abl-interactor 1	0.018
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.018
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.018
Cd33	CD33 antigen	0.018
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.018
Cd209e	CD209e antigen	0.018
Saa3	serum amyloid A 3	0.017
Mucl1	mucin-like 1	0.017
Gp1ba	glycoprotein 1b, alpha polypeptide	0.017
Prkcd	protein kinase C, delta	0.017
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.017
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.017
Dsg4	desmoglein 4	0.016
Gdf15	growth differentiation factor 15	0.016
Zfp423	zinc finger protein 423	0.016
Cd86	CD86 antigen	0.016
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.016
Mid1	midline 1	0.016
Fgfr1	fibroblast growth factor receptor 1	0.016
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.016
Il1f9	interleukin 1 family, member 9	0.016
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.016
Ncf4	neutrophil cytosolic factor 4	0.016
Adam7	a disintegrin and metallopeptidase domain 7	0.015
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.015
Chi3l1	chitinase 3-like 1	0.015
Mgl2	macrophage galactose N-acetyl-galactosamine specific lectin 2	0.015
Fcgr1	Fc receptor, IgG, high affinity I	0.015
Ccl5	chemokine (C-C motif) ligand 5	0.015
Fcrla	Fc receptor-like A	0.015
Mpo	myeloperoxidase	0.015
Il9	interleukin 9	0.015
Ccl17	chemokine (C-C motif) ligand 17	0.015
Mmp12	matrix metallopeptidase 12	0.015
Sfpi1	SFFV proviral integration 1	0.015
Fosl1	fos-like antigen 1	0.014
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.014
Cd7	CD7 antigen	0.014
Htra3	HtrA serine peptidase 3	0.014
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.014
Ccbp2	chemokine binding protein 2	0.014
Sftpd	surfactant associated protein D	0.014
Fasl	Fas ligand (TNF superfamily, member 6)	0.014
Ccl8	chemokine (C-C motif) ligand 8	0.014
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.014
Rhd	Rh blood group, D antigen	0.014
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.014
Lipc	lipase, hepatic	0.014
Dppa3	developmental pluripotency-associated 3	0.014
Zc3h12a	zinc finger CCCH type containing 12A	0.014
Braf	Braf transforming gene	0.013
Kng1	kininogen 1	0.013
Il1rl1	interleukin 1 receptor-like 1	0.013
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.013
Vav2	vav 2 oncogene	0.013
Rag2	recombination activating gene 2	0.013
Ltf	lactotransferrin	0.013	Human
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.013
Irf5	interferon regulatory factor 5	0.013
Otx1	orthodenticle homolog 1 (Drosophila)	0.013
Il12rb1	interleukin 12 receptor, beta 1	0.013
Pilra	paired immunoglobin-like type 2 receptor alpha	0.013
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.013
Gzmd	granzyme D	0.013	Mouse
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.013
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.013
Oprm1	opioid receptor, mu 1	0.013
Atf3	activating transcription factor 3	0.012
Il12a	interleukin 12a	0.012
LOC100504404	h-2 class II histocompatibility antigen, E-K alpha chain-like	0.012
Gdf6	growth differentiation factor 6	0.012	Worm
Aoah	acyloxyacyl hydrolase	0.012
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.012
Slfn1	schlafen 1	0.012
Saa2	serum amyloid A 2	0.012
Mmp13	matrix metallopeptidase 13	0.012
Retnlb	resistin like beta	0.012
Ccr5	chemokine (C-C motif) receptor 5	0.012
Cyld	cylindromatosis (turban tumor syndrome)	0.012
Hes3	hairy and enhancer of split 3 (Drosophila)	0.012
Cmklr1	chemokine-like receptor 1	0.012
Prss28	protease, serine, 28	0.012
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.012
Gm12185	predicted gene 12185	0.012
Nos2	nitric oxide synthase 2, inducible	0.012
Cd177	CD177 antigen	0.012
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.012
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.011
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.011
Ccl7	chemokine (C-C motif) ligand 7	0.011
Brpf1	bromodomain and PHD finger containing, 1	0.011
Irg1	immunoresponsive gene 1	0.011
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.011
Ido1	indoleamine 2,3-dioxygenase 1	0.011
Mos	Moloney sarcoma oncogene	0.011
Pten	phosphatase and tensin homolog	0.011
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.011
Cst7	cystatin F (leukocystatin)	0.011
Cd5l	CD5 antigen-like	0.011
Ctsw	cathepsin W	0.011
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.011
Akr1c6	aldo-keto reductase family 1, member C6	0.010
Cd209a	CD209a antigen	0.010	Mouse
F10	coagulation factor X	0.010
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.010
Rgs16	regulator of G-protein signaling 16	0.010
Gzma	granzyme A	0.010	Mouse
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.010
Gzmc	granzyme C	0.010	Mouse
Ahsg	alpha-2-HS-glycoprotein	0.010	Mouse
Zfp36	zinc finger protein 36	0.010
Smad3	MAD homolog 3 (Drosophila)	0.010
Apcs	serum amyloid P-component	0.010
Havcr2	hepatitis A virus cellular receptor 2	0.010
Prtn3	proteinase 3	0.010	Mouse
Col1a1	collagen, type I, alpha 1	0.010
Il10	interleukin 10	0.010