IMP

Process View

Mus musculus

21 genes annotated in mouse

production of molecular mediator involved in inflammatory response

The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "production of molecular mediator involved in inflammatory response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "production of molecular mediator involved in inflammatory response" (in gray)

Name	Description	Probability	Func Analog Organism
Il10	interleukin 10	0.797
Tnf	tumor necrosis factor	0.751
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.655
Ifng	interferon gamma	0.601
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.598
Ccl2	chemokine (C-C motif) ligand 2	0.511
Tlr4	toll-like receptor 4	0.511
Lyz2	lysozyme 2	0.469
Per2	period homolog 2 (Drosophila)	0.459
Apoe	apolipoprotein E	0.442
Tcra	T-cell receptor alpha chain	0.426
Mmp9	matrix metallopeptidase 9	0.422
Tlr2	toll-like receptor 2	0.408	Mouse
Myd88	myeloid differentiation primary response gene 88	0.404
Il4	interleukin 4	0.397
Rag1	recombination activating gene 1	0.394
Nos2	nitric oxide synthase 2, inducible	0.385
Cd33	CD33 antigen	0.349
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.279
Il17a	interleukin 17A	0.275
Il6	interleukin 6	0.267
Clec4n	C-type lectin domain family 4, member n	0.248
Mefv	Mediterranean fever	0.166
Cd247	CD247 antigen	0.160	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.149
Cd22	CD22 antigen	0.142
Tyrobp	TYRO protein tyrosine kinase binding protein	0.131
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.130
Orai1	ORAI calcium release-activated calcium modulator 1	0.128
Nfam1	Nfat activating molecule with ITAM motif 1	0.125
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.114
Hcst	hematopoietic cell signal transducer	0.112
Mb	myoglobin	0.111
Cd14	CD14 antigen	0.107
C5ar1	complement component 5a receptor 1	0.103
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.100
Fas	Fas (TNF receptor superfamily member 6)	0.097
Spp1	secreted phosphoprotein 1	0.097
Mmp8	matrix metallopeptidase 8	0.095
Ptgs2	prostaglandin-endoperoxide synthase 2	0.094
Ier2	immediate early response 2	0.089
Lair1	leukocyte-associated Ig-like receptor 1	0.087
Ptges	prostaglandin E synthase	0.083
Il13	interleukin 13	0.083
Il1r1	interleukin 1 receptor, type I	0.083
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.082
Igh	immunoglobulin heavy chain complex	0.077
Ccl4	chemokine (C-C motif) ligand 4	0.074
Fos	FBJ osteosarcoma oncogene	0.074
Traf3ip2	TRAF3 interacting protein 2	0.072
Laptm5	lysosomal-associated protein transmembrane 5	0.071
Inpp5d	inositol polyphosphate-5-phosphatase D	0.070
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.068
Cd300ld	CD300 molecule-like family member d	0.068	Mouse
Ikzf1	IKAROS family zinc finger 1	0.068
Stat3	signal transducer and activator of transcription 3	0.065
AF251705	cDNA sequence AF251705	0.064	Mouse
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.063
Tbxas1	thromboxane A synthase 1, platelet	0.058
Zfp36	zinc finger protein 36	0.056
Igk	immunoglobulin kappa chain complex	0.054
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.053
Plek	pleckstrin	0.052
Cd300lb	CD300 antigen like family member B	0.049	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.049
Cd44	CD44 antigen	0.047
Ticam2	toll-like receptor adaptor molecule 2	0.047
Cd19	CD19 antigen	0.046
Msr1	macrophage scavenger receptor 1	0.046
Jun	Jun oncogene	0.046
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.045
Itgal	integrin alpha L	0.044
Clec4d	C-type lectin domain family 4, member d	0.043
C3	complement component 3	0.041
Cd40	CD40 antigen	0.041
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.041
Trem3	triggering receptor expressed on myeloid cells 3	0.040
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.039
Rhob	ras homolog gene family, member B	0.039
Junb	Jun-B oncogene	0.037
Btg2	B-cell translocation gene 2, anti-proliferative	0.036
Treml1	triggering receptor expressed on myeloid cells-like 1	0.036
Ptgir	prostaglandin I receptor (IP)	0.036
Il2rg	interleukin 2 receptor, gamma chain	0.035
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.035
Sfpi1	SFFV proviral integration 1	0.035
Ticam1	toll-like receptor adaptor molecule 1	0.034
Csf1r	colony stimulating factor 1 receptor	0.034
F7	coagulation factor VII	0.034
Unc93b1	unc-93 homolog B1 (C. elegans)	0.033
Rgs14	regulator of G-protein signaling 14	0.033
Slpi	secretory leukocyte peptidase inhibitor	0.033
Cyr61	cysteine rich protein 61	0.032
Lck	lymphocyte protein tyrosine kinase	0.031
Lat	linker for activation of T cells	0.031
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.030
Blk	B lymphoid kinase	0.030
Adm	adrenomedullin	0.029
Il4ra	interleukin 4 receptor, alpha	0.029
Il1rn	interleukin 1 receptor antagonist	0.028
Errfi1	ERBB receptor feedback inhibitor 1	0.028
Btk	Bruton agammaglobulinemia tyrosine kinase	0.028	Rat
Il18rap	interleukin 18 receptor accessory protein	0.028
Fcgr4	Fc receptor, IgG, low affinity IV	0.028
Trem1	triggering receptor expressed on myeloid cells 1	0.026
Irg1	immunoresponsive gene 1	0.026
Il7r	interleukin 7 receptor	0.026
Dok3	docking protein 3	0.026
Mapk1	mitogen-activated protein kinase 1	0.026
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.026
Ccr6	chemokine (C-C motif) receptor 6	0.025
Clec7a	C-type lectin domain family 7, member a	0.025
Chi3l1	chitinase 3-like 1	0.025
Fcgr3	Fc receptor, IgG, low affinity III	0.025
Nlrp3	NLR family, pyrin domain containing 3	0.025
Clec5a	C-type lectin domain family 5, member a	0.025
Lcp1	lymphocyte cytosolic protein 1	0.024
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.024	Rat
Il17f	interleukin 17F	0.024
Sla2	Src-like-adaptor 2	0.024
Ncoa3	nuclear receptor coactivator 3	0.024
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.024
BC013712	cDNA sequence BC013712	0.023
Act1	actin related gene 1	0.023
Rel	reticuloendotheliosis oncogene	0.023
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.023
Blnk	B-cell linker	0.023
Cd180	CD180 antigen	0.023	Mouse
Fam96a	family with sequence similarity 96, member A	0.022
Cd68	CD68 antigen	0.022
Egr1	early growth response 1	0.022
Mcoln2	mucolipin 2	0.022
Gpr132	G protein-coupled receptor 132	0.022
Siglece	sialic acid binding Ig-like lectin E	0.021
Ddit4	DNA-damage-inducible transcript 4	0.021
Zap70	zeta-chain (TCR) associated protein kinase	0.021	Mouse
Ccl3	chemokine (C-C motif) ligand 3	0.021
Ccl6	chemokine (C-C motif) ligand 6	0.021
Cx3cr1	chemokine (C-X3-C) receptor 1	0.021
Atf3	activating transcription factor 3	0.020
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.020
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.020
Ccr1	chemokine (C-C motif) receptor 1	0.019
Nos1	nitric oxide synthase 1, neuronal	0.019
Itgam	integrin alpha M	0.019
Ifngr1	interferon gamma receptor 1	0.019
Pilra	paired immunoglobin-like type 2 receptor alpha	0.019
Muc20	mucin 20	0.019
Asprv1	aspartic peptidase, retroviral-like 1	0.019
Irf5	interferon regulatory factor 5	0.019
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.019
Apobr	apolipoprotein B receptor	0.018
Vav1	vav 1 oncogene	0.018
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.018
Ltc4s	leukotriene C4 synthase	0.018	Mouse
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.018
Il2	interleukin 2	0.018
Irak4	interleukin-1 receptor-associated kinase 4	0.018
Bhlhe40	basic helix-loop-helix family, member e40	0.018
Muc13	mucin 13, epithelial transmembrane	0.018
Per3	period homolog 3 (Drosophila)	0.018
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.018
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.018
Sirpa	signal-regulatory protein alpha	0.017
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.017
Cd177	CD177 antigen	0.017
Fcgr1	Fc receptor, IgG, high affinity I	0.017
Foxn4	forkhead box N4	0.017
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.017	Mouse
Fosb	FBJ osteosarcoma oncogene B	0.017
Hrh1	histamine receptor H1	0.017
Il1b	interleukin 1 beta	0.017
C3ar1	complement component 3a receptor 1	0.016
Dmkn	dermokine	0.016
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.016
Ear5	eosinophil-associated, ribonuclease A family, member 5	0.016
Pim3	proviral integration site 3	0.016
AB124611	cDNA sequence AB124611	0.016
Usp2	ubiquitin specific peptidase 2	0.016
Foxd2	forkhead box D2	0.016
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.016
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.016
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.016
Ifitm6	interferon induced transmembrane protein 6	0.016
Cxcl2	chemokine (C-X-C motif) ligand 2	0.016
F5	coagulation factor V	0.015
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.015
Il10ra	interleukin 10 receptor, alpha	0.015
Itgb2	integrin beta 2	0.015
Cysltr1	cysteinyl leukotriene receptor 1	0.015
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.015
Il1f9	interleukin 1 family, member 9	0.015
Pdcd1	programmed cell death 1	0.015
Litaf	LPS-induced TN factor	0.015
Was	Wiskott-Aldrich syndrome homolog (human)	0.015
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.015
Klf7	Kruppel-like factor 7 (ubiquitous)	0.015
Spry4	sprouty homolog 4 (Drosophila)	0.015
Hk3	hexokinase 3	0.015
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.015
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.015
Il17re	interleukin 17 receptor E	0.014
Myo1f	myosin IF	0.014
Ciita	class II transactivator	0.014
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.014
Chi3l4	chitinase 3-like 4	0.014	Human
Plaur	plasminogen activator, urokinase receptor	0.014
BC018465	cDNA sequence BC018465	0.014
Lif	leukemia inhibitory factor	0.014
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.014
Cry2	cryptochrome 2 (photolyase-like)	0.014
Adam8	a disintegrin and metallopeptidase domain 8	0.014
Tmem40	transmembrane protein 40	0.014
Klf6	Kruppel-like factor 6	0.014
Itgb3	integrin beta 3	0.014
Marco	macrophage receptor with collagenous structure	0.014
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.014
Tlr6	toll-like receptor 6	0.014	Mouse
Krt4	keratin 4	0.013
Tff1	trefoil factor 1	0.013
Csnk1e	casein kinase 1, epsilon	0.013
Rag2	recombination activating gene 2	0.013
Mx2	myxovirus (influenza virus) resistance 2	0.013
Mlph	melanophilin	0.013
Derl3	Der1-like domain family, member 3	0.013
Slamf8	SLAM family member 8	0.013
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.013
Selp	selectin, platelet	0.013
Cblb	Casitas B-lineage lymphoma b	0.013
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.013
Cd28	CD28 antigen	0.013
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.013
Csf1	colony stimulating factor 1 (macrophage)	0.013
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.013
Tlr13	toll-like receptor 13	0.013
Gdf9	growth differentiation factor 9	0.013
Clec1b	C-type lectin domain family 1, member b	0.013
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.013
Expi	extracellular proteinase inhibitor	0.012
Il15ra	interleukin 15 receptor, alpha chain	0.012
Scgb3a1	secretoglobin, family 3A, member 1	0.012
Nog	noggin	0.012
Slfn4	schlafen 4	0.012
Ptprc	protein tyrosine phosphatase, receptor type, C	0.012
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.012
Ccl9	chemokine (C-C motif) ligand 9	0.012
Ltf	lactotransferrin	0.012
Rasal1	RAS protein activator like 1 (GAP1 like)	0.012
Plau	plasminogen activator, urokinase	0.012
Rps15a	ribosomal protein S15A	0.012
Dbi	diazepam binding inhibitor	0.012
Stx11	syntaxin 11	0.012
Npy	neuropeptide Y	0.012
Gjb6	gap junction protein, beta 6	0.012
Ptgfrn	prostaglandin F2 receptor negative regulator	0.011
Ptafr	platelet-activating factor receptor	0.011
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.011
Stat6	signal transducer and activator of transcription 6	0.011
Aoah	acyloxyacyl hydrolase	0.011
Hmox1	heme oxygenase (decycling) 1	0.011
Sftpb	surfactant associated protein B	0.011
Treml4	triggering receptor expressed on myeloid cells-like 4	0.011
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.011
Wisp2	WNT1 inducible signaling pathway protein 2	0.011
Pi16	peptidase inhibitor 16	0.011
Hck	hemopoietic cell kinase	0.011
Fpr1	formyl peptide receptor 1	0.011
Cd86	CD86 antigen	0.011
Sftpd	surfactant associated protein D	0.011
Tlr8	toll-like receptor 8	0.011	Mouse
Pdcd1lg2	programmed cell death 1 ligand 2	0.011
Eya4	eyes absent 4 homolog (Drosophila)	0.011
Irak3	interleukin-1 receptor-associated kinase 3	0.011
Clec4a2	C-type lectin domain family 4, member a2	0.011
Ccr4	chemokine (C-C motif) receptor 4	0.011
Cd300lf	CD300 antigen like family member F	0.011	Mouse
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.010
Sytl3	synaptotagmin-like 3	0.010
Cbr2	carbonyl reductase 2	0.010
Mapk14	mitogen-activated protein kinase 14	0.010
Igsf6	immunoglobulin superfamily, member 6	0.010
Wfdc12	WAP four-disulfide core domain 12	0.010
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.010
Arsi	arylsulfatase i	0.010
Atxn1	ataxin 1	0.010
Cytip	cytohesin 1 interacting protein	0.010
Endou	endonuclease, polyU-specific	0.010
Adamdec1	ADAM-like, decysin 1	0.010
Cldn18	claudin 18	0.010
Prdm1	PR domain containing 1, with ZNF domain	0.010
Gpr84	G protein-coupled receptor 84	0.010
Klf2	Kruppel-like factor 2 (lung)	0.010
Retnlb	resistin like beta	0.010
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.010
Gna15	guanine nucleotide binding protein, alpha 15	0.010
Naip6	NLR family, apoptosis inhibitory protein 6	0.010