IMP

Process View

Mus musculus

8 genes annotated in mouse

commissural neuron axon guidance

The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "commissural neuron axon guidance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "commissural neuron axon guidance" (in gray)

Name	Description	Probability	Func Analog Organism
Efnb2	ephrin B2	0.982
Gli3	GLI-Kruppel family member GLI3	0.973
Acvr1	activin A receptor, type 1	0.945
Efnb1	ephrin B1	0.917
Tgfb2	transforming growth factor, beta 2	0.863
Wnt5a	wingless-related MMTV integration site 5A	0.841
Vegfa	vascular endothelial growth factor A	0.836
Rarg	retinoic acid receptor, gamma	0.831
Slit2	slit homolog 2 (Drosophila)	0.828
Bmp4	bone morphogenetic protein 4	0.822
Axl	AXL receptor tyrosine kinase	0.817	Mouse
Kdr	kinase insert domain protein receptor	0.788
Ednra	endothelin receptor type A	0.777
Ece1	endothelin converting enzyme 1	0.776
Gli2	GLI-Kruppel family member GLI2	0.746
Nfib	nuclear factor I/B	0.736
Ephb2	Eph receptor B2	0.692
Robo1	roundabout homolog 1 (Drosophila)	0.681	Mouse
Epha4	Eph receptor A4	0.665	Mouse
Slit3	slit homolog 3 (Drosophila)	0.631
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.623
Foxc2	forkhead box C2	0.612
Flt4	FMS-like tyrosine kinase 4	0.609
Pax3	paired box gene 3	0.567
Smad6	MAD homolog 6 (Drosophila)	0.544
Jag1	jagged 1	0.533
Gata4	GATA binding protein 4	0.508
Prrx1	paired related homeobox 1	0.506
Sox9	SRY-box containing gene 9	0.494
Tyro3	TYRO3 protein tyrosine kinase 3	0.489	Mouse
Ephb3	Eph receptor B3	0.486	Mouse
Fzd4	frizzled homolog 4 (Drosophila)	0.464	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.453
Fgf8	fibroblast growth factor 8	0.446
Pbx1	pre B-cell leukemia transcription factor 1	0.413
Rara	retinoic acid receptor, alpha	0.313
Gata6	GATA binding protein 6	0.282
Ddr2	discoidin domain receptor family, member 2	0.278
Fgfr1	fibroblast growth factor receptor 1	0.277
Fzd8	frizzled homolog 8 (Drosophila)	0.272	Mouse
Nfic	nuclear factor I/C	0.267	Mouse
Gab1	growth factor receptor bound protein 2-associated protein 1	0.247
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.241
Plxnd1	plexin D1	0.239
Foxc1	forkhead box C1	0.231
Meis2	Meis homeobox 2	0.230
Eya1	eyes absent 1 homolog (Drosophila)	0.229
Chrd	chordin	0.213
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.203
She	src homology 2 domain-containing transforming protein E	0.199
Robo2	roundabout homolog 2 (Drosophila)	0.192	Mouse
Plxna1	plexin A1	0.191
Tnks1bp1	tankyrase 1 binding protein 1	0.189
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.185
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.184
Nrp1	neuropilin 1	0.182
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.172
Emp2	epithelial membrane protein 2	0.163
Gopc	golgi associated PDZ and coiled-coil motif containing	0.160
Irs1	insulin receptor substrate 1	0.160
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.156
Efna5	ephrin A5	0.149
Fgf10	fibroblast growth factor 10	0.145
Sox4	SRY-box containing gene 4	0.141
Flt1	FMS-like tyrosine kinase 1	0.136
Nfix	nuclear factor I/X	0.135	Mouse
Fzd2	frizzled homolog 2 (Drosophila)	0.131	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.126
Zfpm2	zinc finger protein, multitype 2	0.124
Rxra	retinoid X receptor alpha	0.122
Spry4	sprouty homolog 4 (Drosophila)	0.121
Nfia	nuclear factor I/A	0.121	Mouse
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.120
Npr3	natriuretic peptide receptor 3	0.115
Zfhx3	zinc finger homeobox 3	0.114
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.111
Pou3f3	POU domain, class 3, transcription factor 3	0.106
Ldb2	LIM domain binding 2	0.103
Hoxa1	homeobox A1	0.100
Rarb	retinoic acid receptor, beta	0.099
Gata5	GATA binding protein 5	0.096
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.095
Tcf4	transcription factor 4	0.094
Notch3	Notch gene homolog 3 (Drosophila)	0.094
Hoxa3	homeobox A3	0.091
Fzd1	frizzled homolog 1 (Drosophila)	0.090	Mouse
Ednrb	endothelin receptor type B	0.090
Efna1	ephrin A1	0.088
Ptprb	protein tyrosine phosphatase, receptor type, B	0.086
Nos3	nitric oxide synthase 3, endothelial cell	0.084
Sox2	SRY-box containing gene 2	0.082
Fzd7	frizzled homolog 7 (Drosophila)	0.072	Mouse
Epha7	Eph receptor A7	0.071	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.070
Ptprd	protein tyrosine phosphatase, receptor type, D	0.069
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.069
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.068
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.067
Eng	endoglin	0.067
Ptk7	PTK7 protein tyrosine kinase 7	0.065
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.064
Aplnr	apelin receptor	0.063
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.062
Zfhx4	zinc finger homeodomain 4	0.060
Plxna2	plexin A2	0.060
Grb10	growth factor receptor bound protein 10	0.059
Itga3	integrin alpha 3	0.059
Dlx5	distal-less homeobox 5	0.056
Pitx2	paired-like homeodomain transcription factor 2	0.056
Gas1	growth arrest specific 1	0.054
Fign	fidgetin	0.051
Hand2	heart and neural crest derivatives expressed transcript 2	0.051
Wwc2	WW, C2 and coiled-coil domain containing 2	0.050
Mertk	c-mer proto-oncogene tyrosine kinase	0.049	Mouse
Twist1	twist homolog 1 (Drosophila)	0.048
Isl1	ISL1 transcription factor, LIM/homeodomain	0.048
Sox7	SRY-box containing gene 7	0.047
Pax2	paired box gene 2	0.047
Sox18	SRY-box containing gene 18	0.047
Tbx3	T-box 3	0.046
Epha2	Eph receptor A2	0.046	Mouse
Gbx2	gastrulation brain homeobox 2	0.046
Nynrin	NYN domain and retroviral integrase containing	0.045
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.045
Igf1	insulin-like growth factor 1	0.043
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.042
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.041
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.041
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.041
Bmp7	bone morphogenetic protein 7	0.040
Odz3	odd Oz/ten-m homolog 3 (Drosophila)	0.040
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.040
Bmp1	bone morphogenetic protein 1	0.039
Id1	inhibitor of DNA binding 1	0.038
Hic1	hypermethylated in cancer 1	0.037
Tcfap2a	transcription factor AP-2, alpha	0.037
Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.037
Foxg1	forkhead box G1	0.037
Smo	smoothened homolog (Drosophila)	0.036	Zebrafish
Notch1	Notch gene homolog 1 (Drosophila)	0.036
Sox11	SRY-box containing gene 11	0.034
Sh3rf1	SH3 domain containing ring finger 1	0.034
Lama5	laminin, alpha 5	0.033
Vangl2	vang-like 2 (van gogh, Drosophila)	0.032
Hoxa2	homeobox A2	0.032
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.032
Mmp16	matrix metallopeptidase 16	0.031
Dll4	delta-like 4 (Drosophila)	0.031
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.031
Mark1	MAP/microtubule affinity-regulating kinase 1	0.031
Wwtr1	WW domain containing transcription regulator 1	0.030
Fbn2	fibrillin 2	0.030
Neurod1	neurogenic differentiation 1	0.030
Klf3	Kruppel-like factor 3 (basic)	0.029
Dlx1	distal-less homeobox 1	0.029
Cdk14	cyclin-dependent kinase 14	0.029
Pou3f1	POU domain, class 3, transcription factor 1	0.029
Tead2	TEA domain family member 2	0.029
Pdgfb	platelet derived growth factor, B polypeptide	0.029	Mouse
Adrb1	adrenergic receptor, beta 1	0.029
Mpdz	multiple PDZ domain protein	0.029
Ntf3	neurotrophin 3	0.028
Mmp15	matrix metallopeptidase 15	0.028
Cxcl12	chemokine (C-X-C motif) ligand 12	0.028
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.027
Cdh4	cadherin 4	0.027
Ptms	parathymosin	0.026
Ptprk	protein tyrosine phosphatase, receptor type, K	0.026
Otx2	orthodenticle homolog 2 (Drosophila)	0.026
Pcdh18	protocadherin 18	0.025
Col2a1	collagen, type II, alpha 1	0.025
Tspan12	tetraspanin 12	0.025
Smtn	smoothelin	0.024
Prox1	prospero-related homeobox 1	0.024
Myo10	myosin X	0.024
Lama4	laminin, alpha 4	0.024
Pax6	paired box gene 6	0.024
Mesp1	mesoderm posterior 1	0.024
Dock1	dedicator of cytokinesis 1	0.024
Ltbp4	latent transforming growth factor beta binding protein 4	0.024
Wnt7b	wingless-related MMTV integration site 7B	0.024
Hapln1	hyaluronan and proteoglycan link protein 1	0.023
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.022
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.022
Insm1	insulinoma-associated 1	0.022
Notch2	Notch gene homolog 2 (Drosophila)	0.022
Zfp532	zinc finger protein 532	0.022
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.022
Cachd1	cache domain containing 1	0.022
Hbegf	heparin-binding EGF-like growth factor	0.022
Mas1	MAS1 oncogene	0.022
Ephb4	Eph receptor B4	0.022	Mouse
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.022
Jup	junction plakoglobin	0.021
D0H4S114	DNA segment, human D4S114	0.021
Gdnf	glial cell line derived neurotrophic factor	0.021
S1pr3	sphingosine-1-phosphate receptor 3	0.021
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.021
Efna4	ephrin A4	0.021
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.021
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.021
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.021
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.021
Bmp2	bone morphogenetic protein 2	0.020
Zcchc14	zinc finger, CCHC domain containing 14	0.020
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.020
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.020
Dag1	dystroglycan 1	0.020
Lhx9	LIM homeobox protein 9	0.020
Nrp2	neuropilin 2	0.020	Mouse
Cdh6	cadherin 6	0.019
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.019
Lrp5	low density lipoprotein receptor-related protein 5	0.019
Snai2	snail homolog 2 (Drosophila)	0.019
Gjc1	gap junction protein, gamma 1	0.019
Epas1	endothelial PAS domain protein 1	0.019
Dll1	delta-like 1 (Drosophila)	0.019
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018
Ptgfrn	prostaglandin F2 receptor negative regulator	0.018
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.018
Plcb3	phospholipase C, beta 3	0.018
Hipk2	homeodomain interacting protein kinase 2	0.018
Tead1	TEA domain family member 1	0.018
Hes5	hairy and enhancer of split 5 (Drosophila)	0.018
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.018
Neurog2	neurogenin 2	0.017
Neo1	neogenin	0.017
Foxp2	forkhead box P2	0.017
Epha3	Eph receptor A3	0.017	Mouse
Dcc	deleted in colorectal carcinoma	0.017
Yap1	yes-associated protein 1	0.016
Gpr3	G-protein coupled receptor 3	0.016
Efna3	ephrin A3	0.016
Ppara	peroxisome proliferator activated receptor alpha	0.016
Arhgap29	Rho GTPase activating protein 29	0.016
Lamc1	laminin, gamma 1	0.016
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.016
Nog	noggin	0.016
Cxadr	coxsackie virus and adenovirus receptor	0.016
Shh	sonic hedgehog	0.016
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.016
Foxf1a	forkhead box F1a	0.016
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.016
Zfp651	zinc finger protein 651	0.015
Zbtb12	zinc finger and BTB domain containing 12	0.015
Cux2	cut-like homeobox 2	0.015
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.015
Unc5c	unc-5 homolog C (C. elegans)	0.015
Kank2	KN motif and ankyrin repeat domains 2	0.015
Gnrh1	gonadotropin releasing hormone 1	0.015
Efna2	ephrin A2	0.015
Mmp11	matrix metallopeptidase 11	0.015
Pdgfc	platelet-derived growth factor, C polypeptide	0.015
Egln1	EGL nine homolog 1 (C. elegans)	0.015
Efs	embryonal Fyn-associated substrate	0.015
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.014
Col11a1	collagen, type XI, alpha 1	0.014
Bok	BCL2-related ovarian killer protein	0.014
Ghr	growth hormone receptor	0.014
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.014
Foxd1	forkhead box D1	0.014
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.014
Pcdh1	protocadherin 1	0.014
Fjx1	four jointed box 1 (Drosophila)	0.014
Zbtb20	zinc finger and BTB domain containing 20	0.014
Smad3	MAD homolog 3 (Drosophila)	0.014
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.013
Lama1	laminin, alpha 1	0.013
Syt7	synaptotagmin VII	0.013
Zfp703	zinc finger protein 703	0.013
Ptprg	protein tyrosine phosphatase, receptor type, G	0.013
Dlg4	discs, large homolog 4 (Drosophila)	0.013
Thra	thyroid hormone receptor alpha	0.013
Bcl2	B-cell leukemia/lymphoma 2	0.013
Tead3	TEA domain family member 3	0.013
Mkl2	MKL/myocardin-like 2	0.013
Tbx2	T-box 2	0.013
Cdh10	cadherin 10	0.013
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.013
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.013
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.013
Dach1	dachshund 1 (Drosophila)	0.013
Meox2	mesenchyme homeobox 2	0.013
Neurog1	neurogenin 1	0.013
Fosl2	fos-like antigen 2	0.012
Pnoc	prepronociceptin	0.012
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.012
Msx1	homeobox, msh-like 1	0.012
Tbx1	T-box 1	0.012
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.012
Plcg1	phospholipase C, gamma 1	0.012
Ehd2	EH-domain containing 2	0.012
Nrg3	neuregulin 3	0.012
Gja1	gap junction protein, alpha 1	0.012
Pdgfa	platelet derived growth factor, alpha	0.012	Mouse
Prx	periaxin	0.012
Lrp1	low density lipoprotein receptor-related protein 1	0.012
Gli1	GLI-Kruppel family member GLI1	0.012
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.012
Wnt4	wingless-related MMTV integration site 4	0.012
Bcl6b	B-cell CLL/lymphoma 6, member B	0.012
Pcbp4	poly(rC) binding protein 4	0.012
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.012
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.012
Zfp503	zinc finger protein 503	0.012
Jag2	jagged 2	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.011
Angpt1	angiopoietin 1	0.011
Dab1	disabled homolog 1 (Drosophila)	0.011
Cdh5	cadherin 5	0.011
Cdh11	cadherin 11	0.011
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.011
Auts2	autism susceptibility candidate 2	0.011
Hdac7	histone deacetylase 7	0.011
Ar	androgen receptor	0.011
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.011
Fgf18	fibroblast growth factor 18	0.011
Gpc4	glypican 4	0.011
Mef2c	myocyte enhancer factor 2C	0.011
Ebf1	early B-cell factor 1	0.011
Fbln1	fibulin 1	0.011
Arx	aristaless related homeobox	0.011
Pcdh7	protocadherin 7	0.011
Podxl	podocalyxin-like	0.011
C77370	expressed sequence C77370	0.011
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.011
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.011
Ptk2	PTK2 protein tyrosine kinase 2	0.011
Tpbg	trophoblast glycoprotein	0.011
Pcdh10	protocadherin 10	0.011
Bdnf	brain derived neurotrophic factor	0.011
Homer2	homer homolog 2 (Drosophila)	0.011
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.011
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.011
Cdh13	cadherin 13	0.011
Pecam1	platelet/endothelial cell adhesion molecule 1	0.010
Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	0.010
Tspan9	tetraspanin 9	0.010
Pcgf2	polycomb group ring finger 2	0.010
Zfp185	zinc finger protein 185	0.010
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
Nav1	neuron navigator 1	0.010
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.010
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.010
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.010