IMP

Process View

Mus musculus

4 genes annotated in mouse

mammary gland bud morphogenesis

The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mammary gland bud morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mammary gland bud morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	1.000
Shh	sonic hedgehog	0.999
Prrx1	paired related homeobox 1	0.990
Gli3	GLI-Kruppel family member GLI3	0.964
Sox9	SRY-box containing gene 9	0.934
Pax3	paired box gene 3	0.860
Fgfr3	fibroblast growth factor receptor 3	0.834	Mouse
Bmp4	bone morphogenetic protein 4	0.802
Pax2	paired box gene 2	0.693
Ctnnb1	catenin (cadherin associated protein), beta 1	0.686
Fgf10	fibroblast growth factor 10	0.604
Foxc1	forkhead box C1	0.595
Gli2	GLI-Kruppel family member GLI2	0.583
Nkx2-1	NK2 homeobox 1	0.509
Tcf21	transcription factor 21	0.302
Nog	noggin	0.272
Eya1	eyes absent 1 homolog (Drosophila)	0.254
Pten	phosphatase and tensin homolog	0.245
Fgf8	fibroblast growth factor 8	0.229
Trp63	transformation related protein 63	0.219
Fgfr1	fibroblast growth factor receptor 1	0.210	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.209
Vangl2	vang-like 2 (van gogh, Drosophila)	0.193
Egfr	epidermal growth factor receptor	0.171
Apc	adenomatosis polyposis coli	0.171
Fgf9	fibroblast growth factor 9	0.168	Mouse
Rarb	retinoic acid receptor, beta	0.162
Tbx3	T-box 3	0.161
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.157
Lrp6	low density lipoprotein receptor-related protein 6	0.151
Meox2	mesenchyme homeobox 2	0.149
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.148
Twist2	twist homolog 2 (Drosophila)	0.147
Foxa2	forkhead box A2	0.146
Bmp5	bone morphogenetic protein 5	0.141
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.131
Hoxd11	homeobox D11	0.128
Msx2	homeobox, msh-like 2	0.121
Pthlh	parathyroid hormone-like peptide	0.120
Fgfrl1	fibroblast growth factor receptor-like 1	0.116
Dlx5	distal-less homeobox 5	0.116
Pbx1	pre B-cell leukemia transcription factor 1	0.115
Sox2	SRY-box containing gene 2	0.107
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.104
Foxg1	forkhead box G1	0.092
Runx2	runt related transcription factor 2	0.089
Tbx15	T-box 15	0.089
Wnt5a	wingless-related MMTV integration site 5A	0.086
Eda	ectodysplasin-A	0.085
Ptch1	patched homolog 1	0.077
Pitx1	paired-like homeodomain transcription factor 1	0.077
Tbx1	T-box 1	0.075
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.074
Pitx2	paired-like homeodomain transcription factor 2	0.072
Foxc2	forkhead box C2	0.070
Ar	androgen receptor	0.069
Hoxa11	homeobox A11	0.069
Zeb1	zinc finger E-box binding homeobox 1	0.067
Gbx2	gastrulation brain homeobox 2	0.067
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.065
Kl	klotho	0.063
Npr3	natriuretic peptide receptor 3	0.062
Bdnf	brain derived neurotrophic factor	0.062
Esr2	estrogen receptor 2 (beta)	0.061
Fgf18	fibroblast growth factor 18	0.061
Otx2	orthodenticle homolog 2 (Drosophila)	0.057
Npr2	natriuretic peptide receptor 2	0.055
Trp53	transformation related protein 53	0.052
Jag1	jagged 1	0.052
Gata3	GATA binding protein 3	0.052
Hoxa5	homeobox A5	0.046
Ptk7	PTK7 protein tyrosine kinase 7	0.045
Pax8	paired box gene 8	0.045
Chd7	chromodomain helicase DNA binding protein 7	0.041
Col2a1	collagen, type II, alpha 1	0.040
Hoxd13	homeobox D13	0.039
Hoxa10	homeobox A10	0.038
Ret	ret proto-oncogene	0.037
Acan	aggrecan	0.036
Tgfb2	transforming growth factor, beta 2	0.036
Adra1a	adrenergic receptor, alpha 1a	0.035
Nodal	nodal	0.035
Prrx2	paired related homeobox 2	0.035
Chrd	chordin	0.034
Btbd17	BTB (POZ) domain containing 17	0.034
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.033
Isl1	ISL1 transcription factor, LIM/homeodomain	0.033
Hoxa13	homeobox A13	0.032
Pou4f3	POU domain, class 4, transcription factor 3	0.032
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.031
Efnb2	ephrin B2	0.031
Lhx3	LIM homeobox protein 3	0.031
Smo	smoothened homolog (Drosophila)	0.030
Ihh	Indian hedgehog	0.029
Msx1	homeobox, msh-like 1	0.029
Shc3	src homology 2 domain-containing transforming protein C3	0.029
Alx4	aristaless-like homeobox 4	0.029
Hmx2	H6 homeobox 2	0.028
Ctgf	connective tissue growth factor	0.028
Gsc	goosecoid homeobox	0.028
Wnt3a	wingless-related MMTV integration site 3A	0.028
Acvr1	activin A receptor, type 1	0.028
Ptgs2	prostaglandin-endoperoxide synthase 2	0.027
Bmp7	bone morphogenetic protein 7	0.027
Pax9	paired box gene 9	0.027
Lmx1a	LIM homeobox transcription factor 1 alpha	0.027
Rxra	retinoid X receptor alpha	0.027
Tbx5	T-box 5	0.026
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.026
Angpt4	angiopoietin 4	0.025
Hoxa1	homeobox A1	0.025
Lepr	leptin receptor	0.025
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.025
Cntn4	contactin 4	0.025
Clic3	chloride intracellular channel 3	0.024
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.024
Agmat	agmatine ureohydrolase (agmatinase)	0.024
Hes1	hairy and enhancer of split 1 (Drosophila)	0.024
Fgfbp1	fibroblast growth factor binding protein 1	0.024
Emx2	empty spiracles homolog 2 (Drosophila)	0.024
Hand2	heart and neural crest derivatives expressed transcript 2	0.024
Pgr	progesterone receptor	0.023
Thrb	thyroid hormone receptor beta	0.023
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.023
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.023
Lhx1	LIM homeobox protein 1	0.023
Edn3	endothelin 3	0.023
Oprd1	opioid receptor, delta 1	0.022
Rara	retinoic acid receptor, alpha	0.022
Ghr	growth hormone receptor	0.022
Rxrg	retinoid X receptor gamma	0.022
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.021
Pkdcc	protein kinase domain containing, cytoplasmic	0.021
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.021
Spry4	sprouty homolog 4 (Drosophila)	0.021
Vegfa	vascular endothelial growth factor A	0.021
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Nkx3-2	NK3 homeobox 2	0.020
Tecta	tectorin alpha	0.020
Pou3f4	POU domain, class 3, transcription factor 4	0.020
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.020
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.019
Stx1b	syntaxin 1B	0.019
Fgf3	fibroblast growth factor 3	0.019	Mouse
Dlx6	distal-less homeobox 6	0.019
Kcnk3	potassium channel, subfamily K, member 3	0.019
Lep	leptin	0.019
Plcb1	phospholipase C, beta 1	0.019
Hmx3	H6 homeobox 3	0.019
Esr1	estrogen receptor 1 (alpha)	0.019
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.019
Bmp2	bone morphogenetic protein 2	0.019
Fgf22	fibroblast growth factor 22	0.018	Mouse
Krt34	keratin 34	0.018
Grem1	gremlin 1	0.018
Sall4	sal-like 4 (Drosophila)	0.018
Musk	muscle, skeletal, receptor tyrosine kinase	0.018
Crhr2	corticotropin releasing hormone receptor 2	0.017
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.017
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.017
Cdh15	cadherin 15	0.017
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.017
Gli1	GLI-Kruppel family member GLI1	0.017
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.017
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.017
Col1a1	collagen, type I, alpha 1	0.017
Mme	membrane metallo endopeptidase	0.017
Epha4	Eph receptor A4	0.017
Bdkrb2	bradykinin receptor, beta 2	0.017
Ppap2b	phosphatidic acid phosphatase type 2B	0.017
Smad3	MAD homolog 3 (Drosophila)	0.017
Cdh6	cadherin 6	0.017
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.017
Amhr2	anti-Mullerian hormone type 2 receptor	0.017
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.016
Wt1	Wilms tumor 1 homolog	0.016
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.016
Cdh16	cadherin 16	0.016
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.016
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.016
Il6st	interleukin 6 signal transducer	0.016
Slurp1	secreted Ly6/Plaur domain containing 1	0.016
Wnt9b	wingless-type MMTV integration site 9B	0.016
Kif3a	kinesin family member 3A	0.016
Dll1	delta-like 1 (Drosophila)	0.016
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.016
Mylk2	myosin, light polypeptide kinase 2, skeletal muscle	0.016
Tcfap2a	transcription factor AP-2, alpha	0.016
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.016
Magix	MAGI family member, X-linked	0.016
Fgf23	fibroblast growth factor 23	0.015
En1	engrailed 1	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Crhr1	corticotropin releasing hormone receptor 1	0.015
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.015
Tcf15	transcription factor 15	0.015
Hapln1	hyaluronan and proteoglycan link protein 1	0.015
Epha1	Eph receptor A1	0.015
Ldb3	LIM domain binding 3	0.015
Nefm	neurofilament, medium polypeptide	0.015
Gpc3	glypican 3	0.015
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.015
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.015
Mmp16	matrix metallopeptidase 16	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.015
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.015
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.015
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.015
Mgat3	mannoside acetylglucosaminyltransferase 3	0.014
Omp	olfactory marker protein	0.014
Timp3	tissue inhibitor of metalloproteinase 3	0.014
Alx1	ALX homeobox 1	0.014
Lcn8	lipocalin 8	0.014
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.014
Fam164c	family with sequence similarity 164, member C	0.014
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.014
Mid2	midline 2	0.014
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.014
Syt7	synaptotagmin VII	0.014
Dmrt1	doublesex and mab-3 related transcription factor 1	0.014
Lrp4	low density lipoprotein receptor-related protein 4	0.013
Adra1b	adrenergic receptor, alpha 1b	0.013
Gh	growth hormone	0.013
Fut2	fucosyltransferase 2	0.013
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.013
Lef1	lymphoid enhancer binding factor 1	0.013
Tgfa	transforming growth factor alpha	0.013
Has1	hyaluronan synthase1	0.013
Grb10	growth factor receptor bound protein 10	0.013
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.013
Angpt1	angiopoietin 1	0.013
Lmna	lamin A	0.013
Syt1	synaptotagmin I	0.013
Drd3	dopamine receptor D3	0.013
Pth1r	parathyroid hormone 1 receptor	0.013
Tbx10	T-box 10	0.013
Pax6	paired box gene 6	0.013
Prlr	prolactin receptor	0.013
Rb1	retinoblastoma 1	0.013
Ros1	Ros1 proto-oncogene	0.013
Wnt3	wingless-related MMTV integration site 3	0.013
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.012
Tll1	tolloid-like	0.012
Ptgfr	prostaglandin F receptor	0.012
Krt84	keratin 84	0.012
Vsnl1	visinin-like 1	0.012
Spry2	sprouty homolog 2 (Drosophila)	0.012
Otp	orthopedia homolog (Drosophila)	0.012
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.012
Sox11	SRY-box containing gene 11	0.012
Gpr37	G protein-coupled receptor 37	0.012
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.012
Igf1	insulin-like growth factor 1	0.012
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.012
Fgf17	fibroblast growth factor 17	0.012
Rgs6	regulator of G-protein signaling 6	0.012
Smyd1	SET and MYND domain containing 1	0.012
Braf	Braf transforming gene	0.012
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.012
Il25	interleukin 25	0.012
Asgr2	asialoglycoprotein receptor 2	0.012
Ednra	endothelin receptor type A	0.012
Sftpb	surfactant associated protein B	0.012
Hoxa9	homeobox A9	0.012
Itga8	integrin alpha 8	0.012
Nf1	neurofibromatosis 1	0.012
Tpo	thyroid peroxidase	0.012
Foxa1	forkhead box A1	0.012
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.012
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.012
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.012
Notch1	Notch gene homolog 1 (Drosophila)	0.012
Dtna	dystrobrevin alpha	0.012
T	brachyury	0.012
Sstr1	somatostatin receptor 1	0.012
Krt13	keratin 13	0.012
Btbd3	BTB (POZ) domain containing 3	0.012
Ank	progressive ankylosis	0.012
Zp3	zona pellucida glycoprotein 3	0.012
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.011
Cer1	cerberus 1 homolog (Xenopus laevis)	0.011
Tex21	testis expressed gene 21	0.011
Adcy8	adenylate cyclase 8	0.011
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.011
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.011
Mov10l1	Moloney leukemia virus 10-like 1	0.011
Ptprd	protein tyrosine phosphatase, receptor type, D	0.011
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.011
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.011
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.011
Klk6	kallikrein related-peptidase 6	0.011
Cst11	cystatin 11	0.011
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.011
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.011
Fam20c	family with sequence similarity 20, member C	0.011
Slc25a48	solute carrier family 25, member 48	0.011
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.011
Npy5r	neuropeptide Y receptor Y5	0.011
Nppc	natriuretic peptide type C	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Dlg1	discs, large homolog 1 (Drosophila)	0.011
Adrb3	adrenergic receptor, beta 3	0.011
Car7	carbonic anhydrase 7	0.011
Hoxa7	homeobox A7	0.011
Mog	myelin oligodendrocyte glycoprotein	0.011
Ajap1	adherens junction associated protein 1	0.011
Nanog	Nanog homeobox	0.011
Npas1	neuronal PAS domain protein 1	0.011
Foxb2	forkhead box B2	0.011
Gjc2	gap junction protein, gamma 2	0.011
Pcdh12	protocadherin 12	0.011
Bmper	BMP-binding endothelial regulator	0.011
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.011
Thra	thyroid hormone receptor alpha	0.011
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Foxh1	forkhead box H1	0.011
Kcnk4	potassium channel, subfamily K, member 4	0.011
Sstr3	somatostatin receptor 3	0.011
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.010
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.010
Cckbr	cholecystokinin B receptor	0.010
Slc26a5	solute carrier family 26, member 5	0.010
Srd5a2	steroid 5 alpha-reductase 2	0.010
Hoxa2	homeobox A2	0.010
Pou3f3	POU domain, class 3, transcription factor 3	0.010
Cpxm2	carboxypeptidase X 2 (M14 family)	0.010
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.010
Rgs4	regulator of G-protein signaling 4	0.010
Rbl2	retinoblastoma-like 2	0.010
Bcan	brevican	0.010
Tbx4	T-box 4	0.010
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.010
Foxd3	forkhead box D3	0.010
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.010
Psen1	presenilin 1	0.010
BC057022	cDNA sequence BC057022	0.010
Per3	period homolog 3 (Drosophila)	0.010
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.010
Sall1	sal-like 1 (Drosophila)	0.010
Idua	iduronidase, alpha-L-	0.010
Opn4	opsin 4 (melanopsin)	0.010
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.010
Nfia	nuclear factor I/A	0.010
Fgf14	fibroblast growth factor 14	0.010	Mouse