IMP
Process View
positive regulation of natural killer cell mediated cytotoxicity
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of natural killer cell mediated cytotoxicity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.952 | ||
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.913 | Mouse | |
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.907 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.798 | Mouse | |
| Stat5b | signal transducer and activator of transcription 5B | 0.794 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.711 | ||
| Icos | inducible T-cell co-stimulator | 0.696 | ||
| B2m | beta-2 microglobulin | 0.601 | ||
| Gzmk | granzyme K | 0.581 | ||
| H2-K1 | histocompatibility 2, K1, K region | 0.508 | Mouse | |
| Stat5a | signal transducer and activator of transcription 5A | 0.369 | ||
| Gzma | granzyme A | 0.348 | ||
| Gzmb | granzyme B | 0.318 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.289 | ||
| Irf9 | interferon regulatory factor 9 | 0.283 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.270 | Mouse | |
| Tapbp | TAP binding protein | 0.250 | ||
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.249 | ||
| Il18r1 | interleukin 18 receptor 1 | 0.229 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.219 | ||
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.187 | ||
| Itgax | integrin alpha X | 0.139 | ||
| H2-D1 | histocompatibility 2, D region locus 1 | 0.122 | Mouse | |
| Il10 | interleukin 10 | 0.112 | ||
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.108 | Mouse | |
| Trim21 | tripartite motif-containing 21 | 0.100 | ||
| Klra8 | killer cell lectin-like receptor, subfamily A, member 8 | 0.100 | ||
| Klrb1c | killer cell lectin-like receptor subfamily B member 1C | 0.093 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.088 | Mouse | |
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.086 | ||
| Cd244 | CD244 natural killer cell receptor 2B4 | 0.084 | ||
| Cd7 | CD7 antigen | 0.080 | ||
| Klrb1a | killer cell lectin-like receptor subfamily B member 1A | 0.079 | Mouse | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.074 | Mouse | |
| Ctsw | cathepsin W | 0.072 | ||
| Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 | 0.069 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.067 | ||
| Cd180 | CD180 antigen | 0.066 | ||
| Dpep3 | dipeptidase 3 | 0.063 | ||
| Ubd | ubiquitin D | 0.062 | ||
| Aoah | acyloxyacyl hydrolase | 0.058 | ||
| Il2rb | interleukin 2 receptor, beta chain | 0.056 | ||
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.055 | Mouse | |
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.055 | ||
| Itk | IL2-inducible T-cell kinase | 0.054 | ||
| Nfil3 | nuclear factor, interleukin 3, regulated | 0.053 | ||
| Slamf7 | SLAM family member 7 | 0.053 | ||
| BC147527 | cDNA sequence BC147527 | 0.051 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.051 | ||
| Sh2d2a | SH2 domain protein 2A | 0.050 | ||
| Spna1 | spectrin alpha 1 | 0.049 | ||
| Ccr3 | chemokine (C-C motif) receptor 3 | 0.047 | ||
| Klra7 | killer cell lectin-like receptor, subfamily A, member 7 | 0.047 | Mouse | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.047 | ||
| Lepr | leptin receptor | 0.043 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.042 | ||
| Bex6 | brain expressed gene 6 | 0.041 | ||
| H2-Q8 | histocompatibility 2, Q region locus 8 | 0.041 | ||
| H2-Eb1 | histocompatibility 2, class II antigen E beta | 0.040 | ||
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.040 | ||
| Pyhin1 | pyrin and HIN domain family, member 1 | 0.040 | ||
| Ctsb | cathepsin B | 0.038 | ||
| Cp | ceruloplasmin | 0.037 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.035 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.035 | ||
| Gzmc | granzyme C | 0.035 | ||
| Cd160 | CD160 antigen | 0.034 | ||
| Gbp7 | guanylate binding protein 7 | 0.033 | ||
| Il6 | interleukin 6 | 0.032 | ||
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.032 | ||
| Cd96 | CD96 antigen | 0.031 | ||
| Irgm2 | immunity-related GTPase family M member 2 | 0.030 | ||
| Ctsd | cathepsin D | 0.030 | ||
| Fpr1 | formyl peptide receptor 1 | 0.029 | ||
| Il4ra | interleukin 4 receptor, alpha | 0.028 | ||
| Stat2 | signal transducer and activator of transcription 2 | 0.028 | Mouse | |
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.027 | ||
| Klra2 | killer cell lectin-like receptor, subfamily A, member 2 | 0.027 | Mouse | |
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.027 | ||
| Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 0.026 | ||
| Cd3e | CD3 antigen, epsilon polypeptide | 0.025 | ||
| Il2ra | interleukin 2 receptor, alpha chain | 0.025 | ||
| Klra3 | killer cell lectin-like receptor, subfamily A, member 3 | 0.025 | Mouse | |
| H2-Q6 | histocompatibility 2, Q region locus 6 | 0.025 | ||
| Il6st | interleukin 6 signal transducer | 0.024 | ||
| Gbp2 | guanylate binding protein 2 | 0.024 | ||
| Il2 | interleukin 2 | 0.024 | ||
| Itgae | integrin alpha E, epithelial-associated | 0.024 | ||
| Plbd2 | phospholipase B domain containing 2 | 0.023 | ||
| Gcet2 | germinal center expressed transcript 2 | 0.023 | ||
| Itga4 | integrin alpha 4 | 0.023 | ||
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.023 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.023 | ||
| Cd3g | CD3 antigen, gamma polypeptide | 0.023 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.022 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.022 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.022 | ||
| Cxcr6 | chemokine (C-X-C motif) receptor 6 | 0.022 | ||
| Sh2d1b1 | SH2 domain protein 1B1 | 0.022 | ||
| AA408251 | expressed sequence AA408251 | 0.021 | ||
| Klrb1f | killer cell lectin-like receptor subfamily B member 1F | 0.021 | Mouse | |
| Gbp1 | guanylate binding protein 1 | 0.021 | ||
| Ar | androgen receptor | 0.021 | ||
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.021 | ||
| Eomes | eomesodermin homolog (Xenopus laevis) | 0.020 | ||
| Lgals9 | lectin, galactose binding, soluble 9 | 0.020 | ||
| Fcrla | Fc receptor-like A | 0.020 | ||
| AF251705 | cDNA sequence AF251705 | 0.019 | ||
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.019 | ||
| Flt3 | FMS-like tyrosine kinase 3 | 0.019 | ||
| Klre1 | killer cell lectin-like receptor family E member 1 | 0.019 | ||
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.019 | ||
| Cd3d | CD3 antigen, delta polypeptide | 0.019 | ||
| Txk | TXK tyrosine kinase | 0.018 | ||
| Lcn4 | lipocalin 4 | 0.018 | ||
| Gfi1 | growth factor independent 1 | 0.018 | ||
| Ifng | interferon gamma | 0.018 | ||
| Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.018 | ||
| P2ry12 | purinergic receptor P2Y, G-protein coupled 12 | 0.018 | ||
| Tlr4 | toll-like receptor 4 | 0.018 | ||
| Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 0.017 | ||
| AW112010 | expressed sequence AW112010 | 0.017 | ||
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.017 | ||
| Il7r | interleukin 7 receptor | 0.017 | ||
| Parp12 | poly (ADP-ribose) polymerase family, member 12 | 0.017 | ||
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.016 | ||
| Klrc3 | killer cell lectin-like receptor subfamily C, member 3 | 0.016 | ||
| Parp10 | poly (ADP-ribose) polymerase family, member 10 | 0.016 | ||
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.016 | Mouse | |
| Xcr1 | chemokine (C motif) receptor 1 | 0.016 | ||
| Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.016 | ||
| Lgals8 | lectin, galactose binding, soluble 8 | 0.016 | ||
| Cd28 | CD28 antigen | 0.015 | ||
| Kynu | kynureninase (L-kynurenine hydrolase) | 0.015 | ||
| Tcn2 | transcobalamin 2 | 0.015 | ||
| Camk4 | calcium/calmodulin-dependent protein kinase IV | 0.015 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.015 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.014 | ||
| Usp18 | ubiquitin specific peptidase 18 | 0.014 | ||
| Cd2 | CD2 antigen | 0.014 | ||
| Glrp1 | glutamine repeat protein 1 | 0.013 | ||
| H2-T18 | histocompatibility 2, T region locus 18 | 0.013 | ||
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.013 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.013 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.013 | ||
| Tor3a | torsin family 3, member A | 0.013 | ||
| Il12rb1 | interleukin 12 receptor, beta 1 | 0.013 | ||
| Adar | adenosine deaminase, RNA-specific | 0.012 | ||
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.012 | ||
| H2-Q5 | histocompatibility 2, Q region locus 5 | 0.012 | ||
| Pfdn5 | prefoldin 5 | 0.012 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.012 | ||
| Gzmd | granzyme D | 0.012 | ||
| Iigp1 | interferon inducible GTPase 1 | 0.012 | ||
| Fpr2 | formyl peptide receptor 2 | 0.012 | ||
| H2-M2 | histocompatibility 2, M region locus 2 | 0.012 | ||
| Car1 | carbonic anhydrase 1 | 0.012 | ||
| Gpr33 | G protein-coupled receptor 33 | 0.012 | ||
| Cmklr1 | chemokine-like receptor 1 | 0.011 | ||
| Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.011 | ||
| Casp12 | caspase 12 | 0.011 | ||
| Hgf | hepatocyte growth factor | 0.011 | ||
| Ms4a4b | membrane-spanning 4-domains, subfamily A, member 4B | 0.011 | ||
| Zbtb37 | zinc finger and BTB domain containing 37 | 0.011 | ||
| Clec2i | C-type lectin domain family 2, member i | 0.011 | ||
| Cd8a | CD8 antigen, alpha chain | 0.011 | ||
| Cst7 | cystatin F (leukocystatin) | 0.011 | ||
| Dnase1l3 | deoxyribonuclease 1-like 3 | 0.011 | ||
| Stap1 | signal transducing adaptor family member 1 | 0.011 | ||
| Cd84 | CD84 antigen | 0.011 | ||
| Clec4b1 | C-type lectin domain family 4, member b1 | 0.011 | ||
| Pdcd6ip | programmed cell death 6 interacting protein | 0.010 | ||
| F2rl2 | coagulation factor II (thrombin) receptor-like 2 | 0.010 | ||
| H2-Aa | histocompatibility 2, class II antigen A, alpha | 0.010 | ||
| Nckap1l | NCK associated protein 1 like | 0.010 | ||
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.010 | ||
| Herc6 | hect domain and RLD 6 | 0.010 | ||
| Irg1 | immunoresponsive gene 1 | 0.010 | ||
| Tmem106a | transmembrane protein 106A | 0.010 | ||
| Igtp | interferon gamma induced GTPase | 0.010 | ||
| Gm2a | GM2 ganglioside activator protein | 0.010 | ||
| Cyp4v3 | cytochrome P450, family 4, subfamily v, polypeptide 3 | 0.010 | ||
| Tbx21 | T-box 21 | 0.010 |