IMP

Process View

Mus musculus

2 genes annotated in mouse

regulation of transcription from rna polymerase ii promoter in response to hypoxia

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transcription from rna polymerase ii promoter in response to hypoxia"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of transcription from rna polymerase ii promoter in response to hypoxia" (in gray)

Name	Description	Probability	Func Analog Organism
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.999
Notch2	Notch gene homolog 2 (Drosophila)	0.998	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.921
Bcl2	B-cell leukemia/lymphoma 2	0.907
Vegfa	vascular endothelial growth factor A	0.886	Human
Ptgs2	prostaglandin-endoperoxide synthase 2	0.876
Jag1	jagged 1	0.836
Rxra	retinoid X receptor alpha	0.748
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.697
Egfr	epidermal growth factor receptor	0.692
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.665
Ctnnb1	catenin (cadherin associated protein), beta 1	0.663
Egr1	early growth response 1	0.649
Lepr	leptin receptor	0.588
Gata4	GATA binding protein 4	0.560
Pitx2	paired-like homeodomain transcription factor 2	0.460
Psen1	presenilin 1	0.440
Fgfr2	fibroblast growth factor receptor 2	0.438
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.411
Pten	phosphatase and tensin homolog	0.394
Nab2	Ngfi-A binding protein 2	0.389
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.343
Lama5	laminin, alpha 5	0.327
Fos	FBJ osteosarcoma oncogene	0.320
Notch1	Notch gene homolog 1 (Drosophila)	0.301
Foxc1	forkhead box C1	0.267
Tbx1	T-box 1	0.263
Fgf8	fibroblast growth factor 8	0.261
Acvr1	activin A receptor, type 1	0.250
Dll1	delta-like 1 (Drosophila)	0.229
Hif1a	hypoxia inducible factor 1, alpha subunit	0.224	Human
Gdnf	glial cell line derived neurotrophic factor	0.224
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.222
Bmp4	bone morphogenetic protein 4	0.216
Efnb2	ephrin B2	0.210
Chd7	chromodomain helicase DNA binding protein 7	0.196
Gata6	GATA binding protein 6	0.190
Egln1	EGL nine homolog 1 (C. elegans)	0.182
Egr2	early growth response 2	0.177	Mouse
Tgfb2	transforming growth factor, beta 2	0.175
Wt1	Wilms tumor 1 homolog	0.167	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.155
Hoxa1	homeobox A1	0.151
Epas1	endothelial PAS domain protein 1	0.149
Col4a3	collagen, type IV, alpha 3	0.148
Vhl	von Hippel-Lindau tumor suppressor	0.132	Human
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.123
Jun	Jun oncogene	0.119
Foxc2	forkhead box C2	0.114
Dusp1	dual specificity phosphatase 1	0.112
Smad3	MAD homolog 3 (Drosophila)	0.110
Nab1	Ngfi-A binding protein 1	0.107
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.105
Ren1	renin 1 structural	0.100
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.098
Vangl2	vang-like 2 (van gogh, Drosophila)	0.096
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.094
Foxo1	forkhead box O1	0.093
Ednra	endothelin receptor type A	0.087
Cd151	CD151 antigen	0.086
Sox9	SRY-box containing gene 9	0.085
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.084
Pkd1	polycystic kidney disease 1 homolog	0.080
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.078
Junb	Jun-B oncogene	0.076
Hand2	heart and neural crest derivatives expressed transcript 2	0.072
Klf6	Kruppel-like factor 6	0.072
Rarb	retinoic acid receptor, beta	0.071
Psen2	presenilin 2	0.068
Ar	androgen receptor	0.067
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.066	Human
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.066
Tcfap2a	transcription factor AP-2, alpha	0.065
Kdr	kinase insert domain protein receptor	0.065
Pbx1	pre B-cell leukemia transcription factor 1	0.063
Wwtr1	WW domain containing transcription regulator 1	0.061
Klf3	Kruppel-like factor 3 (basic)	0.059
Adam17	a disintegrin and metallopeptidase domain 17	0.059
Ntf3	neurotrophin 3	0.057
Smo	smoothened homolog (Drosophila)	0.055
Shh	sonic hedgehog	0.052
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.052
Btg2	B-cell translocation gene 2, anti-proliferative	0.050
Cav1	caveolin 1, caveolae protein	0.049
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.049
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.046
Ece1	endothelin converting enzyme 1	0.046
Tcf21	transcription factor 21	0.046
Kiss1	KiSS-1 metastasis-suppressor	0.045
Crebbp	CREB binding protein	0.045
Itga3	integrin alpha 3	0.045
Skil	SKI-like	0.043
Prkci	protein kinase C, iota	0.040
Fosb	FBJ osteosarcoma oncogene B	0.040
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.039
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.039
Wsb1	WD repeat and SOCS box-containing 1	0.039
Yap1	yes-associated protein 1	0.038
Ahr	aryl-hydrocarbon receptor	0.038
Sox4	SRY-box containing gene 4	0.037
Nphs2	nephrosis 2 homolog, podocin (human)	0.037
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.036
Plxnd1	plexin D1	0.036
Cyr61	cysteine rich protein 61	0.034
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.033
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.033
She	src homology 2 domain-containing transforming protein E	0.032
Pparg	peroxisome proliferator activated receptor gamma	0.031
Gja1	gap junction protein, alpha 1	0.031
Pax3	paired box gene 3	0.030
Apoe	apolipoprotein E	0.030
Esr1	estrogen receptor 1 (alpha)	0.029
Tgfbr2	transforming growth factor, beta receptor II	0.029
Fas	Fas (TNF receptor superfamily member 6)	0.028
Zfp36	zinc finger protein 36	0.028
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.028
Zfhx3	zinc finger homeobox 3	0.027
Agtr1a	angiotensin II receptor, type 1a	0.027
Apc	adenomatosis polyposis coli	0.027
Dll4	delta-like 4 (Drosophila)	0.027
Kit	kit oncogene	0.027
Lyz2	lysozyme 2	0.026
Klf7	Kruppel-like factor 7 (ubiquitous)	0.025
Smad7	MAD homolog 7 (Drosophila)	0.025
Gli3	GLI-Kruppel family member GLI3	0.025
Rara	retinoic acid receptor, alpha	0.025
Zfp362	zinc finger protein 362	0.025
Amhr2	anti-Mullerian hormone type 2 receptor	0.024
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.024
Mcl1	myeloid cell leukemia sequence 1	0.024
Irs2	insulin receptor substrate 2	0.023
Tbx2	T-box 2	0.023
Pax2	paired box gene 2	0.023
Pdgfb	platelet derived growth factor, B polypeptide	0.023
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.023
Egfl7	EGF-like domain 7	0.022
Rarg	retinoic acid receptor, gamma	0.022
Smad4	MAD homolog 4 (Drosophila)	0.022
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.022
Trp53	transformation related protein 53	0.022
Smad5	MAD homolog 5 (Drosophila)	0.020
Pkd2	polycystic kidney disease 2	0.020
Efnb1	ephrin B1	0.020
Gata3	GATA binding protein 3	0.020
Hoxa3	homeobox A3	0.020
Mgrn1	mahogunin, ring finger 1	0.019
Hoxa2	homeobox A2	0.019
Isl1	ISL1 transcription factor, LIM/homeodomain	0.019
Atf3	activating transcription factor 3	0.019
Hes1	hairy and enhancer of split 1 (Drosophila)	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Zfpm2	zinc finger protein, multitype 2	0.019
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.018
Fzd4	frizzled homolog 4 (Drosophila)	0.018
Cdh5	cadherin 5	0.018
Nrp1	neuropilin 1	0.017
Bnc1	basonuclin 1	0.017
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.017
Klf4	Kruppel-like factor 4 (gut)	0.017
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.017
Smad1	MAD homolog 1 (Drosophila)	0.017
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.017
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.017
Cic	capicua homolog (Drosophila)	0.017
Idua	iduronidase, alpha-L-	0.017
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.016
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.016
Bdkrb2	bradykinin receptor, beta 2	0.016
Ltbp1	latent transforming growth factor beta binding protein 1	0.015
Zswim6	zinc finger, SWIM domain containing 6	0.015
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.015
Npc1	Niemann Pick type C1	0.015
Socs3	suppressor of cytokine signaling 3	0.015
Braf	Braf transforming gene	0.014
Ripply3	ripply3 homolog (zebrafish)	0.014
Bhlhe40	basic helix-loop-helix family, member e40	0.014
Emid2	EMI domain containing 2	0.014
Phf13	PHD finger protein 13	0.014
Sox7	SRY-box containing gene 7	0.014
Acvr2b	activin receptor IIB	0.014
Zfp503	zinc finger protein 503	0.014
Rhob	ras homolog gene family, member B	0.013
Inhbb	inhibin beta-B	0.013
Foxa2	forkhead box A2	0.013
Fosl2	fos-like antigen 2	0.013
Smad6	MAD homolog 6 (Drosophila)	0.013
Ep300	E1A binding protein p300	0.013
Tbx18	T-box18	0.013
Midn	midnolin	0.013
Msl1	male-specific lethal 1 homolog (Drosophila)	0.013
Pmp22	peripheral myelin protein 22	0.013
Gna13	guanine nucleotide binding protein, alpha 13	0.013
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.013
Cxcr4	chemokine (C-X-C motif) receptor 4	0.013
Mkl2	MKL/myocardin-like 2	0.013
Meox2	mesenchyme homeobox 2	0.013
Amotl2	angiomotin-like 2	0.013
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
Megf8	multiple EGF-like-domains 8	0.012
Csnk1e	casein kinase 1, epsilon	0.012
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.012
Sh3rf1	SH3 domain containing ring finger 1	0.012
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.012
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.012
Stat3	signal transducer and activator of transcription 3	0.012
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.012
Btg1	B-cell translocation gene 1, anti-proliferative	0.012
Cxcr7	chemokine (C-X-C motif) receptor 7	0.012
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.012
Wbp2	WW domain binding protein 2	0.012
Igfbp5	insulin-like growth factor binding protein 5	0.012
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.012
Ski	ski sarcoma viral oncogene homolog (avian)	0.011
Klf10	Kruppel-like factor 10	0.011
Kitl	kit ligand	0.011
Tgfbr1	transforming growth factor, beta receptor I	0.011
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.011
Fli1	Friend leukemia integration 1	0.011
Nf2	neurofibromatosis 2	0.011
Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.011
Nf1	neurofibromatosis 1	0.011
Lhx9	LIM homeobox protein 9	0.011
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.011
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.011
Phldb1	pleckstrin homology-like domain, family B, member 1	0.011
Znrf4	zinc and ring finger 4	0.011
Lox	lysyl oxidase	0.010
Gli2	GLI-Kruppel family member GLI2	0.010
Traf6	TNF receptor-associated factor 6	0.010
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.010
Irs1	insulin receptor substrate 1	0.010
Stk4	serine/threonine kinase 4	0.010
Ehd3	EH-domain containing 3	0.010