IMP

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Mus musculus

4 genes annotated in mouse

Multi-species View

positive regulation of t cell anergy

GO:0002669

Any process that activates or increases the frequency, rate, or extent of T cell anergy.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t cell anergy"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of t cell anergy" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.884
Stat3	signal transducer and activator of transcription 3	0.765
Cyld	cylindromatosis (turban tumor syndrome)	0.663
Foxp1	forkhead box P1	0.468	Mouse
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.377
Zap70	zeta-chain (TCR) associated protein kinase	0.345
Grb10	growth factor receptor bound protein 10	0.256
Traf6	TNF receptor-associated factor 6	0.239
Cd3g	CD3 antigen, gamma polypeptide	0.227	Mouse
Cd6	CD6 antigen	0.169
Cd3d	CD3 antigen, delta polypeptide	0.163	Mouse
Smad7	MAD homolog 7 (Drosophila)	0.143
Tcra	T-cell receptor alpha chain	0.142
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.140
Trp53	transformation related protein 53	0.139
Foxp2	forkhead box P2	0.128	Mouse
Cd8b1	CD8 antigen, beta chain 1	0.123
Smad6	MAD homolog 6 (Drosophila)	0.119
Fyn	Fyn proto-oncogene	0.119
Ttc7	tetratricopeptide repeat domain 7	0.117
Il6st	interleukin 6 signal transducer	0.116
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.115
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.114
Itk	IL2-inducible T-cell kinase	0.112
Lat	linker for activation of T cells	0.109
Ticam1	toll-like receptor adaptor molecule 1	0.108
Gli2	GLI-Kruppel family member GLI2	0.106
Grb2	growth factor receptor bound protein 2	0.104
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.098
Cd27	CD27 antigen	0.094
Cd2	CD2 antigen	0.092
Icos	inducible T-cell co-stimulator	0.081
Lck	lymphocyte protein tyrosine kinase	0.080
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.071
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.069
Ctsw	cathepsin W	0.066
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.064
Smad1	MAD homolog 1 (Drosophila)	0.063
Tbl1x	transducin (beta)-like 1 X-linked	0.059
Phf2	PHD finger protein 2	0.059
Cd8a	CD8 antigen, alpha chain	0.058
Egfr	epidermal growth factor receptor	0.056
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.055
Prkcq	protein kinase C, theta	0.052
Cd96	CD96 antigen	0.051
Rnf11	ring finger protein 11	0.050
Cblb	Casitas B-lineage lymphoma b	0.049
Nkd2	naked cuticle 2 homolog (Drosophila)	0.049
Trp53bp1	transformation related protein 53 binding protein 1	0.045
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.045
Sh2d1a	SH2 domain protein 1A	0.044
Cldn3	claudin 3	0.044
Smad4	MAD homolog 4 (Drosophila)	0.043
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.042
Prdx6	peroxiredoxin 6	0.041
Cxcr6	chemokine (C-X-C motif) receptor 6	0.039
Mysm1	myb-like, SWIRM and MPN domains 1	0.039
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.039
Gimap7	GTPase, IMAP family member 7	0.039
Gzma	granzyme A	0.038
Gab1	growth factor receptor bound protein 2-associated protein 1	0.038
Stat5b	signal transducer and activator of transcription 5B	0.036
Atp11c	ATPase, class VI, type 11C	0.035
Cd2ap	CD2-associated protein	0.033
Smc1a	structural maintenance of chromosomes 1A	0.033
Sorbs1	sorbin and SH3 domain containing 1	0.033
Gimap3	GTPase, IMAP family member 3	0.033
Git2	G protein-coupled receptor kinase-interactor 2	0.032
Gtf2i	general transcription factor II I	0.032
Pmepa1	prostate transmembrane protein, androgen induced 1	0.032
Myd88	myeloid differentiation primary response gene 88	0.031
Sh2d2a	SH2 domain protein 2A	0.031
Crb3	crumbs homolog 3 (Drosophila)	0.031
Arid1b	AT rich interactive domain 1B (SWI-like)	0.030
BC021614	cDNA sequence BC021614	0.028
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.027
Bach2	BTB and CNC homology 2	0.027
Ccr7	chemokine (C-C motif) receptor 7	0.027
Wbp1	WW domain binding protein 1	0.027
Rhoh	ras homolog gene family, member H	0.026
Axin1	axin 1	0.026
Itgb7	integrin beta 7	0.026
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.025
Ralbp1	ralA binding protein 1	0.025
Sh3kbp1	SH3-domain kinase binding protein 1	0.025
Tmem79	transmembrane protein 79	0.025
Tspan32	tetraspanin 32	0.025
Phf21a	PHD finger protein 21A	0.025
Cd5	CD5 antigen	0.025
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.024
Nkg7	natural killer cell group 7 sequence	0.024
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.024
Ikzf1	IKAROS family zinc finger 1	0.024
Kit	kit oncogene	0.024
Ubc	ubiquitin C	0.023
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.023	Mouse
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.023
Pum1	pumilio 1 (Drosophila)	0.023
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.023
Stim1	stromal interaction molecule 1	0.022
Sit1	suppression inducing transmembrane adaptor 1	0.022
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.022
Smad5	MAD homolog 5 (Drosophila)	0.022
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.022	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.022
Prrg2	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2	0.022
Zfp26	zinc finger protein 26	0.022
Ahr	aryl-hydrocarbon receptor	0.021
Tbc1d4	TBC1 domain family, member 4	0.021
Sh2b2	SH2B adaptor protein 2	0.021
4921513D23Rik	RIKEN cDNA 4921513D23 gene	0.021
Sept1	septin 1	0.021
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.021
C430003N24Rik	RIKEN cDNA C430003N24 gene	0.020
Ly6d	lymphocyte antigen 6 complex, locus D	0.020
Cxcr3	chemokine (C-X-C motif) receptor 3	0.020
Chd4	chromodomain helicase DNA binding protein 4	0.019
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.019
Mfsd6l	major facilitator superfamily domain containing 6-like	0.019
Ikzf3	IKAROS family zinc finger 3	0.019
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.019
Fam160b1	family with sequence similarity 160, member B1	0.019
Pard6a	par-6 (partitioning defective 6,) homolog alpha (C. elegans)	0.019
Hhex	hematopoietically expressed homeobox	0.018
Vav1	vav 1 oncogene	0.018
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.018
Txk	TXK tyrosine kinase	0.018
Pglyrp2	peptidoglycan recognition protein 2	0.018
Cd7	CD7 antigen	0.017
Usp8	ubiquitin specific peptidase 8	0.017
Erbb2ip	Erbb2 interacting protein	0.017
Pdcd6ip	programmed cell death 6 interacting protein	0.017
Fam168a	family with sequence similarity 168, member A	0.017
Sipa1l1	signal-induced proliferation-associated 1 like 1	0.017
1190002N15Rik	RIKEN cDNA 1190002N15 gene	0.017
Purb	purine rich element binding protein B	0.017
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.016
Lad1	ladinin	0.016
Il17re	interleukin 17 receptor E	0.016
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.016
Stat4	signal transducer and activator of transcription 4	0.016
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.016
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.016
Skil	SKI-like	0.015
Zfp362	zinc finger protein 362	0.015
Folr4	folate receptor 4 (delta)	0.015
Slamf6	SLAM family member 6	0.015
Lcor	ligand dependent nuclear receptor corepressor	0.015
Sp1	trans-acting transcription factor 1	0.015
Atxn2l	ataxin 2-like	0.015
Zcchc11	zinc finger, CCHC domain containing 11	0.015
Prrc2b	proline-rich coiled-coil 2B	0.015
Tbc1d22b	TBC1 domain family, member 22B	0.015
Hook3	hook homolog 3 (Drosophila)	0.015
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.015
Cdk6	cyclin-dependent kinase 6	0.015
Sos1	son of sevenless homolog 1 (Drosophila)	0.014
Flt1	FMS-like tyrosine kinase 1	0.014
Traf3ip3	TRAF3 interacting protein 3	0.014
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.014	Mouse
Gatad2b	GATA zinc finger domain containing 2B	0.014
Srrm2	serine/arginine repetitive matrix 2	0.014
Xrn1	5'-3' exoribonuclease 1	0.014
Ikbkg	inhibitor of kappaB kinase gamma	0.014
Meox2	mesenchyme homeobox 2	0.014
Cd28	CD28 antigen	0.014
Eif4b	eukaryotic translation initiation factor 4B	0.014
Hdlbp	high density lipoprotein (HDL) binding protein	0.014
Malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.014
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.014
Epha1	Eph receptor A1	0.014
Batf	basic leucine zipper transcription factor, ATF-like	0.013
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.013
Nck1	non-catalytic region of tyrosine kinase adaptor protein 1	0.013
Arhgef16	Rho guanine nucleotide exchange factor (GEF) 16	0.013
A930004J17Rik	RIKEN cDNA A930004J17 gene	0.013
Stxbp2	syntaxin binding protein 2	0.013
Med15	mediator complex subunit 15	0.013
Tet2	tet oncogene family member 2	0.013
Nf2	neurofibromatosis 2	0.013
Tcf7	transcription factor 7, T-cell specific	0.013
Marveld3	MARVEL (membrane-associating) domain containing 3	0.013
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.013
Sytl3	synaptotagmin-like 3	0.013
Sla2	Src-like-adaptor 2	0.013
Cxcr5	chemokine (C-X-C motif) receptor 5	0.012
Dlg3	discs, large homolog 3 (Drosophila)	0.012
Jak1	Janus kinase 1	0.012
Rictor	RPTOR independent companion of MTOR, complex 2	0.012
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.012
Skap1	src family associated phosphoprotein 1	0.012
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.012
Eps8l2	EPS8-like 2	0.012
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.012
Bcl11b	B-cell leukemia/lymphoma 11B	0.012
Chd9	chromodomain helicase DNA binding protein 9	0.012
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.012
Acly	ATP citrate lyase	0.012
Zfhx3	zinc finger homeobox 3	0.012
Scn2a1	sodium channel, voltage-gated, type II, alpha 1	0.012
Rab25	RAB25, member RAS oncogene family	0.012
Dgcr2	DiGeorge syndrome critical region gene 2	0.012
Ctnnd1	catenin (cadherin associated protein), delta 1	0.012
Zswim6	zinc finger, SWIM domain containing 6	0.012
Pla2g2d	phospholipase A2, group IID	0.012
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.012
Cbl	Casitas B-lineage lymphoma	0.012	Mouse
Ssh2	slingshot homolog 2 (Drosophila)	0.012
Btbd7	BTB (POZ) domain containing 7	0.012
Phkb	phosphorylase kinase beta	0.012
Il17rb	interleukin 17 receptor B	0.011
Lpin3	lipin 3	0.011
Ccl20	chemokine (C-C motif) ligand 20	0.011
Nfil3	nuclear factor, interleukin 3, regulated	0.011
Csnk1g1	casein kinase 1, gamma 1	0.011
Kif1b	kinesin family member 1B	0.011
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.011
Huwe1	HECT, UBA and WWE domain containing 1	0.011
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.011
Tbc1d10c	TBC1 domain family, member 10c	0.011
Stat5a	signal transducer and activator of transcription 5A	0.011
Usp22	ubiquitin specific peptidase 22	0.011
Ptprd	protein tyrosine phosphatase, receptor type, D	0.011
Slc44a3	solute carrier family 44, member 3	0.011
Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.011
Ino80d	INO80 complex subunit D	0.011
Fign	fidgetin	0.011
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.011
Cxcl17	chemokine (C-X-C motif) ligand 17	0.011
Pknox1	Pbx/knotted 1 homeobox	0.011
Scnn1b	sodium channel, nonvoltage-gated 1 beta	0.011
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.010	Mouse
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.010
Secisbp2l	SECIS binding protein 2-like	0.010
Ubn2	ubinuclein 2	0.010
Ptk2	PTK2 protein tyrosine kinase 2	0.010
Slamf1	signaling lymphocytic activation molecule family member 1	0.010
Usp47	ubiquitin specific peptidase 47	0.010
Caprin1	cell cycle associated protein 1	0.010
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.010
Vps26b	vacuolar protein sorting 26 homolog B (yeast)	0.010
D030002E05Rik	RIKEN cDNA D030002E05 gene	0.010
Bbx	bobby sox homolog (Drosophila)	0.010
Fam193a	family with sequence similarity 193, member A	0.010
Hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.010
Akap13	A kinase (PRKA) anchor protein 13	0.010