IMP

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Mus musculus

18 genes annotated in mouse

Multi-species View

alpha amino acid catabolic process

GO:1901606

The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "alpha amino acid catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "alpha amino acid catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Esr1	estrogen receptor 1 (alpha)	0.507
Mmp9	matrix metallopeptidase 9	0.394
Il6	interleukin 6	0.322
Slc12a1	solute carrier family 12, member 1	0.280
Lepr	leptin receptor	0.245
Il10	interleukin 10	0.239
Ptgs2	prostaglandin-endoperoxide synthase 2	0.232
Apoe	apolipoprotein E	0.213
Prlr	prolactin receptor	0.202
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.190
Lep	leptin	0.175
Vdr	vitamin D receptor	0.172
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.149
Cav1	caveolin 1, caveolae protein	0.145
Plg	plasminogen	0.143
Mccc1	methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)	0.135
Vegfa	vascular endothelial growth factor A	0.135
Ivd	isovaleryl coenzyme A dehydrogenase	0.125	Rat
Nos3	nitric oxide synthase 3, endothelial cell	0.122	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.109
Cat	catalase	0.089
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.089
Pxmp2	peroxisomal membrane protein 2	0.087
Acadsb	acyl-Coenzyme A dehydrogenase, short/branched chain	0.087
Srebf2	sterol regulatory element binding factor 2	0.082
Npy2r	neuropeptide Y receptor Y2	0.081
Ldlr	low density lipoprotein receptor	0.078
Gcdh	glutaryl-Coenzyme A dehydrogenase	0.076
Pparg	peroxisome proliferator activated receptor gamma	0.073
Ak3	adenylate kinase 3	0.066
Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	0.064
Tdo2	tryptophan 2,3-dioxygenase	0.063
Acy1	aminoacylase 1	0.063
Cbs	cystathionine beta-synthase	0.063
Nos1	nitric oxide synthase 1, neuronal	0.058	Mouse Rat
Timp4	tissue inhibitor of metalloproteinase 4	0.054
Mut	methylmalonyl-Coenzyme A mutase	0.054
Adora2a	adenosine A2a receptor	0.053
Pipox	pipecolic acid oxidase	0.050
Tst	thiosulfate sulfurtransferase, mitochondrial	0.047
Immt	inner membrane protein, mitochondrial	0.044
Gstz1	glutathione transferase zeta 1 (maleylacetoacetate isomerase)	0.044
Gstk1	glutathione S-transferase kappa 1	0.044
Ccl2	chemokine (C-C motif) ligand 2	0.043
Ndrg2	N-myc downstream regulated gene 2	0.042
Adck3	aarF domain containing kinase 3	0.040
Pcx	pyruvate carboxylase	0.039
Ftcd	formiminotransferase cyclodeaminase	0.039
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.039
Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	0.038
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.038
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.038
Dbt	dihydrolipoamide branched chain transacylase E2	0.037
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.035
Asgr2	asialoglycoprotein receptor 2	0.035
Ccbl2	cysteine conjugate-beta lyase 2	0.035
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.034
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.034
Cps1	carbamoyl-phosphate synthetase 1	0.034
Upp2	uridine phosphorylase 2	0.034
Tgfb1	transforming growth factor, beta 1	0.033
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.033
Ccr2	chemokine (C-C motif) receptor 2	0.032
Plau	plasminogen activator, urokinase	0.032
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.032
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.032
Gnmt	glycine N-methyltransferase	0.032
Echdc3	enoyl Coenzyme A hydratase domain containing 3	0.032
Prkg1	protein kinase, cGMP-dependent, type I	0.031
Ifng	interferon gamma	0.031
Gpld1	glycosylphosphatidylinositol specific phospholipase D1	0.031
Nos2	nitric oxide synthase 2, inducible	0.031
Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	0.031
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.031
Smad3	MAD homolog 3 (Drosophila)	0.030
Gjb1	gap junction protein, beta 1	0.030
Slc38a3	solute carrier family 38, member 3	0.029
Aldh7a1	aldehyde dehydrogenase family 7, member A1	0.028
Got1	glutamate oxaloacetate transaminase 1, soluble	0.028
Acad11	acyl-Coenzyme A dehydrogenase family, member 11	0.028
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.028
Csf1	colony stimulating factor 1 (macrophage)	0.027
Fgf1	fibroblast growth factor 1	0.027
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.026
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.026
Qprt	quinolinate phosphoribosyltransferase	0.026
Sord	sorbitol dehydrogenase	0.026
Slc25a15	solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15	0.025
Foxg1	forkhead box G1	0.025
Pccb	propionyl Coenzyme A carboxylase, beta polypeptide	0.025
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.025
1300001I01Rik	RIKEN cDNA 1300001I01 gene	0.024
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.024
Gstm1	glutathione S-transferase, mu 1	0.024
Fas	Fas (TNF receptor superfamily member 6)	0.024
Ppt2	palmitoyl-protein thioesterase 2	0.023
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.022
Hgd	homogentisate 1, 2-dioxygenase	0.022
Tph2	tryptophan hydroxylase 2	0.022
Bhmt2	betaine-homocysteine methyltransferase 2	0.022
Itgb3	integrin beta 3	0.022
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.022
Col4a3	collagen, type IV, alpha 3	0.022
Selenbp1	selenium binding protein 1	0.022
Dpyd	dihydropyrimidine dehydrogenase	0.021
Acad8	acyl-Coenzyme A dehydrogenase family, member 8	0.021
Nipsnap1	4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)	0.021
Klf15	Kruppel-like factor 15	0.021
Arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1	0.021
Rac1	RAS-related C3 botulinum substrate 1	0.020
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.020
Gstt1	glutathione S-transferase, theta 1	0.019
Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.019
Pm20d1	peptidase M20 domain containing 1	0.019
Pou5f1	POU domain, class 5, transcription factor 1	0.019
Il1r1	interleukin 1 receptor, type I	0.019
Plat	plasminogen activator, tissue	0.018
Intu	inturned planar cell polarity effector homolog (Drosophila)	0.018
Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	0.018
Pecr	peroxisomal trans-2-enoyl-CoA reductase	0.018
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.018
Prodh	proline dehydrogenase	0.018
Nags	N-acetylglutamate synthase	0.018
Macrod1	MACRO domain containing 1	0.018
Hpx	hemopexin	0.018
Tmem150a	transmembrane protein 150A	0.018
Car14	carbonic anhydrase 14	0.018
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.017
Nat1	N-acetyl transferase 1	0.017
Ugcg	UDP-glucose ceramide glucosyltransferase	0.017
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.017
Sardh	sarcosine dehydrogenase	0.017	Fly
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.017
Clec4f	C-type lectin domain family 4, member f	0.017
D10Jhu81e	DNA segment, Chr 10, Johns Hopkins University 81 expressed	0.017
Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	0.017
Adi1	acireductone dioxygenase 1	0.017
Abhd14b	abhydrolase domain containing 14b	0.017
Aldh4a1	aldehyde dehydrogenase 4 family, member A1	0.017	Yeast
Asgr1	asialoglycoprotein receptor 1	0.017
Pcmtd2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	0.017
Ptgs1	prostaglandin-endoperoxide synthase 1	0.017
Acp6	acid phosphatase 6, lysophosphatidic	0.017
Dmgdh	dimethylglycine dehydrogenase precursor	0.017
Lcat	lecithin cholesterol acyltransferase	0.017
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.016
Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5	0.016
BC048355	cDNA sequence BC048355	0.016
Elf1	E74-like factor 1	0.016
Agtr2	angiotensin II receptor, type 2	0.016
Iyd	iodotyrosine deiodinase	0.016
Dgat2	diacylglycerol O-acyltransferase 2	0.016
Def8	differentially expressed in FDCP 8	0.016
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.016
Ar	androgen receptor	0.016
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.016
Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	0.016
Abhd3	abhydrolase domain containing 3	0.016
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.015
Epas1	endothelial PAS domain protein 1	0.015
Mag	myelin-associated glycoprotein	0.015
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.015
Rdh7	retinol dehydrogenase 7	0.015
Galm	galactose mutarotase	0.015
Gamt	guanidinoacetate methyltransferase	0.015
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.015
Lpin1	lipin 1	0.015
Pcca	propionyl-Coenzyme A carboxylase, alpha polypeptide	0.015
Tcl1b3	T-cell leukemia/lymphoma 1B, 3	0.015
Saa4	serum amyloid A 4	0.015
Amacr	alpha-methylacyl-CoA racemase	0.015
Ephx2	epoxide hydrolase 2, cytoplasmic	0.015
Pbld1	phenazine biosynthesis-like protein domain containing 1	0.015
Ptges	prostaglandin E synthase	0.015
Gldc	glycine decarboxylase	0.015
Tcea3	transcription elongation factor A (SII), 3	0.015
Cyp4f15	cytochrome P450, family 4, subfamily f, polypeptide 15	0.015
Mlxipl	MLX interacting protein-like	0.014
Mettl7a1	methyltransferase like 7A1	0.014
Galk1	galactokinase 1	0.014
Alx1	ALX homeobox 1	0.014
Gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2	0.014
Aass	aminoadipate-semialdehyde synthase	0.014
Aadat	aminoadipate aminotransferase	0.014
Tlcd1	TLC domain containing 1	0.014
Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	0.014
Fam151a	family with sequence simliarity 151, member A	0.014
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.014
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.014
Pgls	6-phosphogluconolactonase	0.014
Phyh	phytanoyl-CoA hydroxylase	0.014
Mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase	0.014
Sgk2	serum/glucocorticoid regulated kinase 2	0.014
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.014
Fmo5	flavin containing monooxygenase 5	0.014
Gja1	gap junction protein, alpha 1	0.014
Acat1	acetyl-Coenzyme A acetyltransferase 1	0.014
Nphs2	nephrosis 2 homolog, podocin (human)	0.014
Scd1	stearoyl-Coenzyme A desaturase 1	0.014
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.014
Nlrp6	NLR family, pyrin domain containing 6	0.014
Orm3	orosomucoid 3	0.014
Hhat	hedgehog acyltransferase	0.013
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.013
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.013
Osbpl1a	oxysterol binding protein-like 1A	0.013
C1qbp	complement component 1, q subcomponent binding protein	0.013
Agxt2l1	alanine-glyoxylate aminotransferase 2-like 1	0.013
Pzp	pregnancy zone protein	0.013
Mug1	murinoglobulin 1	0.013
Pah	phenylalanine hydroxylase	0.013	Worm
Akap1	A kinase (PRKA) anchor protein 1	0.013
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.013
Bpnt1	bisphosphate 3'-nucleotidase 1	0.013
Pla2g12b	phospholipase A2, group XIIB	0.013
Mlycd	malonyl-CoA decarboxylase	0.013
Gstm6	glutathione S-transferase, mu 6	0.013
Suox	sulfite oxidase	0.013
Cyb5b	cytochrome b5 type B	0.013
Gm10334	predicted gene 10334	0.013
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.013
Gpt	glutamic pyruvic transaminase, soluble	0.013
Sult1d1	sulfotransferase family 1D, member 1	0.013
Adipoq	adiponectin, C1Q and collagen domain containing	0.013
Lrp6	low density lipoprotein receptor-related protein 6	0.013
Cryz	crystallin, zeta	0.013
Agtr1a	angiotensin II receptor, type 1a	0.013
4933436I01Rik	RIKEN cDNA 4933436I01 gene	0.013
Hrsp12	heat-responsive protein 12	0.013
H2-Ke6	H2-K region expressed gene 6	0.012
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	0.012
Alb	albumin	0.012
Adk	adenosine kinase	0.012
Ghr	growth hormone receptor	0.012
Reg2	regenerating islet-derived 2	0.012
C9	complement component 9	0.012
Cth	cystathionase (cystathionine gamma-lyase)	0.012
Dsg1a	desmoglein 1 alpha	0.012
Apoc4	apolipoprotein C-IV	0.012
Ces3a	carboxylesterase 3A	0.012
Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	0.012	Human Rat
Homer1	homer homolog 1 (Drosophila)	0.012
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.012
Akr7a5	aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)	0.012
Slc47a1	solute carrier family 47, member 1	0.012
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.012
Aldh8a1	aldehyde dehydrogenase 8 family, member A1	0.012
Sall1	sal-like 1 (Drosophila)	0.012
Mettl7a2	methyltransferase like 7A2	0.012
Mat1a	methionine adenosyltransferase I, alpha	0.012
Pfkm	phosphofructokinase, muscle	0.012
Car5a	carbonic anhydrase 5a, mitochondrial	0.012
Nt5e	5' nucleotidase, ecto	0.012
Gphn	gephyrin	0.012
Hrg	histidine-rich glycoprotein	0.012
Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase	0.012
Masp2	mannan-binding lectin serine peptidase 2	0.012
Oat	ornithine aminotransferase	0.012
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.012
Cdh9	cadherin 9	0.012
Atg10	autophagy-related 10 (yeast)	0.012
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.012
Dpys	dihydropyrimidinase	0.012
Mgmt	O-6-methylguanine-DNA methyltransferase	0.011
Hoga1	4-hydroxy-2-oxoglutarate aldolase 1	0.011
Apoa5	apolipoprotein A-V	0.011
Fggy	FGGY carbohydrate kinase domain containing	0.011
Akr1d1	aldo-keto reductase family 1, member D1	0.011
Rab26	RAB26, member RAS oncogene family	0.011
Mia1	melanoma inhibitory activity 1	0.011
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.011
Vdac1	voltage-dependent anion channel 1	0.011
Klc4	kinesin light chain 4	0.011
Snta1	syntrophin, acidic 1	0.011
Azgp1	alpha-2-glycoprotein 1, zinc	0.011
Col18a1	collagen, type XVIII, alpha 1	0.011
Abcg8	ATP-binding cassette, sub-family G (WHITE), member 8	0.011
Nnt	nicotinamide nucleotide transhydrogenase	0.011
Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	0.011
Csad	cysteine sulfinic acid decarboxylase	0.011
Cyp27a1	cytochrome P450, family 27, subfamily a, polypeptide 1	0.011
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.011
Slc25a3	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3	0.011
Rab5b	RAB5B, member RAS oncogene family	0.011
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.011
Rtn4ip1	reticulon 4 interacting protein 1	0.011
Jak2	Janus kinase 2	0.011
Dlg4	discs, large homolog 4 (Drosophila)	0.011
Mpzl2	myelin protein zero-like 2	0.011
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.011
Cbfb	core binding factor beta	0.011
Cyp4f14	cytochrome P450, family 4, subfamily f, polypeptide 14	0.011
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.011
Dhcr24	24-dehydrocholesterol reductase	0.011
Pgrmc1	progesterone receptor membrane component 1	0.011
Cdo1	cysteine dioxygenase 1, cytosolic	0.011
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.010
Gpr37l1	G protein-coupled receptor 37-like 1	0.010
Apon	apolipoprotein N	0.010
Ppara	peroxisome proliferator activated receptor alpha	0.010
Etnk2	ethanolamine kinase 2	0.010
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.010
G6pc	glucose-6-phosphatase, catalytic	0.010
Ccdc164	coiled-coil domain containing 164	0.010
Apoa2	apolipoprotein A-II	0.010
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.010
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.010
D2hgdh	D-2-hydroxyglutarate dehydrogenase	0.010
Ahr	aryl-hydrocarbon receptor	0.010
Dcxr	dicarbonyl L-xylulose reductase	0.010
Ndst2	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2	0.010
Hpn	hepsin	0.010
Reg3a	regenerating islet-derived 3 alpha	0.010
Mrvi1	MRV integration site 1	0.010
Polr3gl	polymerase (RNA) III (DNA directed) polypeptide G like	0.010
Glyctk	glycerate kinase	0.010
Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	0.010
Scrn2	secernin 2	0.010
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.010
Fah	fumarylacetoacetate hydrolase	0.010
Ass1	argininosuccinate synthetase 1	0.010
Sfxn1	sideroflexin 1	0.010
Aspg	asparaginase homolog (S. cerevisiae)	0.010