IMP

Process View

Mus musculus

15 genes annotated in mouse

Multi-species View

regulation of translational initiation

GO:0006446

Any process that modulates the frequency, rate or extent of translational initiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of translational initiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of translational initiation" (in gray)

Name	Description	Probability	Func Analog Organism
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.987
Rarg	retinoic acid receptor, gamma	0.945	Mouse
Pax2	paired box gene 2	0.889
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.814
Eif3a	eukaryotic translation initiation factor 3, subunit A	0.754
Ikzf1	IKAROS family zinc finger 1	0.723
Ifng	interferon gamma	0.711
Eif4g1	eukaryotic translation initiation factor 4, gamma 1	0.618	Human
Il7	interleukin 7	0.591
Pax8	paired box gene 8	0.550
Lta	lymphotoxin A	0.475	Mouse
Il2	interleukin 2	0.408
Ltb	lymphotoxin B	0.355
Ece1	endothelin converting enzyme 1	0.339
Rxra	retinoid X receptor alpha	0.298
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.289	Mouse
Shh	sonic hedgehog	0.269
Rara	retinoic acid receptor, alpha	0.260
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.257	Human
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.255
Cxcr5	chemokine (C-X-C motif) receptor 5	0.250
Pten	phosphatase and tensin homolog	0.249
Fgfr2	fibroblast growth factor receptor 2	0.243
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.239
Il4	interleukin 4	0.210
Tox	thymocyte selection-associated high mobility group box	0.198
Eif4e	eukaryotic translation initiation factor 4E	0.158
Tnf	tumor necrosis factor	0.157
Il10	interleukin 10	0.152
Cxcl13	chemokine (C-X-C motif) ligand 13	0.149
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.149	Mouse
Eif3b	eukaryotic translation initiation factor 3, subunit B	0.143	Human
Pklr	pyruvate kinase liver and red blood cell	0.125
Eif4a1	eukaryotic translation initiation factor 4A1	0.114
Pitx2	paired-like homeodomain transcription factor 2	0.111
Ncl	nucleolin	0.107
Ghr	growth hormone receptor	0.105
Sox4	SRY-box containing gene 4	0.101
Fxr1	fragile X mental retardation gene 1, autosomal homolog	0.097	Mouse
Exoc6	exocyst complex component 6	0.096
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.096
Cd19	CD19 antigen	0.090
Bmp4	bone morphogenetic protein 4	0.081
Fmr1	fragile X mental retardation syndrome 1 homolog	0.078
Spna1	spectrin alpha 1	0.076
Csde1	cold shock domain containing E1, RNA binding	0.071
Eya1	eyes absent 1 homolog (Drosophila)	0.070
Emx2	empty spiracles homolog 2 (Drosophila)	0.069
Paip2b	poly(A) binding protein interacting protein 2B	0.067
Pabpc1	poly(A) binding protein, cytoplasmic 1	0.065	Yeast
Gata5	GATA binding protein 5	0.063
Tef	thyrotroph embryonic factor	0.063
Tcf3	transcription factor 3	0.060
Fas	Fas (TNF receptor superfamily member 6)	0.059
Rarb	retinoic acid receptor, beta	0.056	Mouse
Fgfrl1	fibroblast growth factor receptor-like 1	0.055
Phf17	PHD finger protein 17	0.055
Tcra	T-cell receptor alpha chain	0.053
Lhx1	LIM homeobox protein 1	0.053
Prdm16	PR domain containing 16	0.051
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.050
Hbb-b2	hemoglobin, beta adult minor chain	0.049
Il2rg	interleukin 2 receptor, gamma chain	0.049
Cd28	CD28 antigen	0.047
Wnt9b	wingless-type MMTV integration site 9B	0.046
Esr1	estrogen receptor 1 (alpha)	0.045
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.044
Notch2	Notch gene homolog 2 (Drosophila)	0.043
Foxc1	forkhead box C1	0.042
Cd247	CD247 antigen	0.042
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.042
Rxrb	retinoid X receptor beta	0.041	Mouse
Spry2	sprouty homolog 2 (Drosophila)	0.036
Traf4	TNF receptor associated factor 4	0.035
Mapk11	mitogen-activated protein kinase 11	0.033
Cetn2	centrin 2	0.032
Fyn	Fyn proto-oncogene	0.032
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.031
Trp63	transformation related protein 63	0.031
ORF61	open reading frame 61	0.031
Sox9	SRY-box containing gene 9	0.031
Ppard	peroxisome proliferator activator receptor delta	0.031
Fgf8	fibroblast growth factor 8	0.030
Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	0.029
Med25	mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)	0.029
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.029
Rag1	recombination activating gene 1	0.028
Eif2ak1	eukaryotic translation initiation factor 2 alpha kinase 1	0.027
Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25	0.027
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.027
Bmper	BMP-binding endothelial regulator	0.027
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.026
Otx2	orthodenticle homolog 2 (Drosophila)	0.026
Igh	immunoglobulin heavy chain complex	0.025
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.025
Vegfa	vascular endothelial growth factor A	0.025
Lat	linker for activation of T cells	0.025
Cd40	CD40 antigen	0.024
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.024
Chd7	chromodomain helicase DNA binding protein 7	0.024
Trp53	transformation related protein 53	0.024
Zeb1	zinc finger E-box binding homeobox 1	0.024
Ldb1	LIM domain binding 1	0.023
Trib3	tribbles homolog 3 (Drosophila)	0.022
Gata4	GATA binding protein 4	0.022
Dnm2	dynamin 2	0.021
Ube2o	ubiquitin-conjugating enzyme E2O	0.021
Pbx1	pre B-cell leukemia transcription factor 1	0.021
Eif3c	eukaryotic translation initiation factor 3, subunit C	0.020
Id2	inhibitor of DNA binding 2	0.020
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.020
Rps6	ribosomal protein S6	0.020
Jag1	jagged 1	0.019
Fgfr1	fibroblast growth factor receptor 1	0.019
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.019
Btk	Bruton agammaglobulinemia tyrosine kinase	0.019
Lck	lymphocyte protein tyrosine kinase	0.018
Itk	IL2-inducible T-cell kinase	0.018
Fam53a	family with sequence similarity 53, member A	0.018
Nfic	nuclear factor I/C	0.018
Mdm4	transformed mouse 3T3 cell double minute 4	0.018
Gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1	0.018
Gypa	glycophorin A	0.018
Icos	inducible T-cell co-stimulator	0.018
Qk	quaking	0.018
Pcnp	PEST proteolytic signal containing nuclear protein	0.017
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.017
Vps72	vacuolar protein sorting 72 (yeast)	0.017
Klf1	Kruppel-like factor 1 (erythroid)	0.017
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.017
Fbxo15	F-box protein 15	0.017
Dbp	D site albumin promoter binding protein	0.017
Gli2	GLI-Kruppel family member GLI2	0.016
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.016
Prox1	prospero-related homeobox 1	0.016
Vdr	vitamin D receptor	0.016
Eif3i	eukaryotic translation initiation factor 3, subunit I	0.016
Gna11	guanine nucleotide binding protein, alpha 11	0.016
Capn1	calpain 1	0.016
Psen1	presenilin 1	0.015
Map2k2	mitogen-activated protein kinase kinase 2	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.015
Ncln	nicalin homolog (zebrafish)	0.015
Sox11	SRY-box containing gene 11	0.015
Prf1	perforin 1 (pore forming protein)	0.015
Lef1	lymphoid enhancer binding factor 1	0.015
Tgfb2	transforming growth factor, beta 2	0.015
Gzmb	granzyme B	0.015
Vipr1	vasoactive intestinal peptide receptor 1	0.015
Pax3	paired box gene 3	0.015
Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.015
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Rcan1	regulator of calcineurin 1	0.014
Fgf10	fibroblast growth factor 10	0.014
Wdtc1	WD and tetratricopeptide repeats 1	0.014
Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1	0.014
Duox2	dual oxidase 2	0.014
Rel	reticuloendotheliosis oncogene	0.014
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.014
Npm1	nucleophosmin 1	0.014
Irf2bp1	interferon regulatory factor 2 binding protein 1	0.014
Ggnbp1	gametogenetin binding protein 1	0.014
Rhd	Rh blood group, D antigen	0.014
Il15	interleukin 15	0.014
Bzw1	basic leucine zipper and W2 domains 1	0.013
Bag6	BCL2-associated athanogene 6	0.013
Il2rb	interleukin 2 receptor, beta chain	0.013
Tlr4	toll-like receptor 4	0.013
Psme4	proteasome (prosome, macropain) activator subunit 4	0.013
Card11	caspase recruitment domain family, member 11	0.013
Vangl2	vang-like 2 (van gogh, Drosophila)	0.013
Gpr132	G protein-coupled receptor 132	0.013
Bmp7	bone morphogenetic protein 7	0.013
Sall4	sal-like 4 (Drosophila)	0.013
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.013
Soat2	sterol O-acyltransferase 2	0.013
Vcp	valosin containing protein	0.013
Ttc33	tetratricopeptide repeat domain 33	0.013
Pou2af1	POU domain, class 2, associating factor 1	0.012
Agrp	agouti related protein	0.012
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.012
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.012
Zfp358	zinc finger protein 358	0.012
Gata3	GATA binding protein 3	0.012
Hoxd11	homeobox D11	0.012
Lamc1	laminin, gamma 1	0.012
Abcf1	ATP-binding cassette, sub-family F (GCN20), member 1	0.012
Eif4a2	eukaryotic translation initiation factor 4A2	0.012
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)	0.012
Lemd2	LEM domain containing 2	0.012
Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein	0.012
Pitpnb	phosphatidylinositol transfer protein, beta	0.012
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.012
Cacybp	calcyclin binding protein	0.012
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.012
Hoxa5	homeobox A5	0.012
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.011
Epn1	epsin 1	0.011
Sap30l	SAP30-like	0.011
Aoah	acyloxyacyl hydrolase	0.011
Trim24	tripartite motif-containing 24	0.011
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.011
Jak3	Janus kinase 3	0.011
Hsf1	heat shock factor 1	0.011
Meox2	mesenchyme homeobox 2	0.011
Dio3	deiodinase, iodothyronine type III	0.011
Gli3	GLI-Kruppel family member GLI3	0.011
Mpv17	MpV17 mitochondrial inner membrane protein	0.011
Setd8	SET domain containing (lysine methyltransferase) 8	0.011
Mesp1	mesoderm posterior 1	0.011
Set	SET nuclear oncogene	0.011
Foxg1	forkhead box G1	0.010
Zc3h12a	zinc finger CCCH type containing 12A	0.010
Lrp5	low density lipoprotein receptor-related protein 5	0.010
Foxc2	forkhead box C2	0.010
6330577E15Rik	RIKEN cDNA 6330577E15 gene	0.010
Eif3e	eukaryotic translation initiation factor 3, subunit E	0.010
Polrmt	polymerase (RNA) mitochondrial (DNA directed)	0.010
Txk	TXK tyrosine kinase	0.010