IMP

Process View

Mus musculus

6 genes annotated in mouse

anterior commissure morphogenesis

GO:0021960

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "anterior commissure morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "anterior commissure morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Pax2	paired box gene 2	1.000
Foxc1	forkhead box C1	1.000
Emx1	empty spiracles homolog 1 (Drosophila)	1.000
Pax3	paired box gene 3	1.000
Sox9	SRY-box containing gene 9	1.000
Rarg	retinoic acid receptor, gamma	1.000
Pax6	paired box gene 6	1.000
Fgfr1	fibroblast growth factor receptor 1	1.000
Smo	smoothened homolog (Drosophila)	1.000
Fgf8	fibroblast growth factor 8	1.000
Emx2	empty spiracles homolog 2 (Drosophila)	1.000
Otx1	orthodenticle homolog 1 (Drosophila)	1.000
Bmp4	bone morphogenetic protein 4	1.000
Tcfap2a	transcription factor AP-2, alpha	0.999
Pitx2	paired-like homeodomain transcription factor 2	0.999
Tbx1	T-box 1	0.999
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.998
Foxg1	forkhead box G1	0.998
Vangl2	vang-like 2 (van gogh, Drosophila)	0.997
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.997
En1	engrailed 1	0.997	Fly
Foxc2	forkhead box C2	0.997
Gbx2	gastrulation brain homeobox 2	0.996
Sox2	SRY-box containing gene 2	0.996
Gli2	GLI-Kruppel family member GLI2	0.991
Rarb	retinoic acid receptor, beta	0.990
Eya1	eyes absent 1 homolog (Drosophila)	0.990
Chd7	chromodomain helicase DNA binding protein 7	0.988
Shh	sonic hedgehog	0.987	Fly
Prrx1	paired related homeobox 1	0.985
Nrp1	neuropilin 1	0.984
Ctnnb1	catenin (cadherin associated protein), beta 1	0.981
Pbx1	pre B-cell leukemia transcription factor 1	0.962
Dlx5	distal-less homeobox 5	0.959
Sox11	SRY-box containing gene 11	0.957
Pten	phosphatase and tensin homolog	0.955
Tgfb2	transforming growth factor, beta 2	0.954
Fgfr3	fibroblast growth factor receptor 3	0.944
Msx1	homeobox, msh-like 1	0.942
Isl1	ISL1 transcription factor, LIM/homeodomain	0.940
Rxra	retinoid X receptor alpha	0.934
Rara	retinoic acid receptor, alpha	0.930
Lmx1b	LIM homeobox transcription factor 1 beta	0.923
Lmx1a	LIM homeobox transcription factor 1 alpha	0.921
Vegfa	vascular endothelial growth factor A	0.915
Jag1	jagged 1	0.900
Ednra	endothelin receptor type A	0.898
Chrd	chordin	0.893
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.879
Zeb1	zinc finger E-box binding homeobox 1	0.875
En2	engrailed 2	0.872	Fly
Msx2	homeobox, msh-like 2	0.871
Nog	noggin	0.863
Fgf10	fibroblast growth factor 10	0.860
Hoxa1	homeobox A1	0.860
Lhx1	LIM homeobox protein 1	0.842
Gata4	GATA binding protein 4	0.836
Nfib	nuclear factor I/B	0.825
Bmp7	bone morphogenetic protein 7	0.814
Efnb2	ephrin B2	0.776
Ece1	endothelin converting enzyme 1	0.706
Sox4	SRY-box containing gene 4	0.659
Hes1	hairy and enhancer of split 1 (Drosophila)	0.657
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.655
Wnt1	wingless-related MMTV integration site 1	0.613
Prrx2	paired related homeobox 2	0.563
Hes5	hairy and enhancer of split 5 (Drosophila)	0.499
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.497
Unc5c	unc-5 homolog C (C. elegans)	0.460
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.434
Nfia	nuclear factor I/A	0.431	Mouse
Runx2	runt related transcription factor 2	0.426
Col2a1	collagen, type II, alpha 1	0.423
Ptch1	patched homolog 1	0.407
Hand2	heart and neural crest derivatives expressed transcript 2	0.392
Epha4	Eph receptor A4	0.374
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.366
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.345
Wnt5a	wingless-related MMTV integration site 5A	0.340
Psen1	presenilin 1	0.335
Nynrin	NYN domain and retroviral integrase containing	0.333
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.328
Hoxa2	homeobox A2	0.289
Twist2	twist homolog 2 (Drosophila)	0.288
Lef1	lymphoid enhancer binding factor 1	0.270
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.260
Neurog2	neurogenin 2	0.256
Ebf3	early B-cell factor 3	0.254
Wnt9b	wingless-type MMTV integration site 9B	0.251
Dcx	doublecortin	0.246
Ntn1	netrin 1	0.242
Fgf9	fibroblast growth factor 9	0.237
Lrp6	low density lipoprotein receptor-related protein 6	0.232
Meox2	mesenchyme homeobox 2	0.228
Bdnf	brain derived neurotrophic factor	0.226
Efnb1	ephrin B1	0.225
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.220
Pou4f2	POU domain, class 4, transcription factor 2	0.209
Ar	androgen receptor	0.196
Zic3	zinc finger protein of the cerebellum 3	0.192
Lhx5	LIM homeobox protein 5	0.186
Nfix	nuclear factor I/X	0.177	Mouse
Thra	thyroid hormone receptor alpha	0.161
Efna2	ephrin A2	0.152
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.151
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.146
Notch1	Notch gene homolog 1 (Drosophila)	0.141
Gsc	goosecoid homeobox	0.141
Tbx3	T-box 3	0.137
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.136
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.134
Zfp423	zinc finger protein 423	0.128
Hoxa3	homeobox A3	0.127
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.119
Hand1	heart and neural crest derivatives expressed transcript 1	0.116
Alx4	aristaless-like homeobox 4	0.114
Nf1	neurofibromatosis 1	0.113
Id4	inhibitor of DNA binding 4	0.111
Dclk1	doublecortin-like kinase 1	0.103
Dcc	deleted in colorectal carcinoma	0.102
Disp1	dispatched homolog 1 (Drosophila)	0.101
Reln	reelin	0.100
Nrp2	neuropilin 2	0.099
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.098
Fzd8	frizzled homolog 8 (Drosophila)	0.097
Neurod1	neurogenic differentiation 1	0.095
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.094
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.091
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.091
Cbln3	cerebellin 3 precursor protein	0.090
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.086
Gas1	growth arrest specific 1	0.084
Notch3	Notch gene homolog 3 (Drosophila)	0.083
Egfr	epidermal growth factor receptor	0.080
Pitx1	paired-like homeodomain transcription factor 1	0.080
Lhx9	LIM homeobox protein 9	0.079
Acvr1	activin A receptor, type 1	0.076
Foxa2	forkhead box A2	0.070
Zfhx3	zinc finger homeobox 3	0.067
Hoxa5	homeobox A5	0.067
Bhlhe22	basic helix-loop-helix family, member e22	0.066
Smad6	MAD homolog 6 (Drosophila)	0.066
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.065
Ltbr	lymphotoxin B receptor	0.064
Pou4f3	POU domain, class 4, transcription factor 3	0.063
Npr2	natriuretic peptide receptor 2	0.062
Rb1	retinoblastoma 1	0.062
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.061
Lhx2	LIM homeobox protein 2	0.059
Sox21	SRY-box containing gene 21	0.057
Itga3	integrin alpha 3	0.056
Abca3	ATP-binding cassette, sub-family A (ABC1), member 3	0.054
Fam83h	family with sequence similarity 83, member H	0.053
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.052
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.051
Irx1	Iroquois related homeobox 1 (Drosophila)	0.051
Insm1	insulinoma-associated 1	0.051
Tnks1bp1	tankyrase 1 binding protein 1	0.050
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.050
Meis2	Meis homeobox 2	0.049
Lamc1	laminin, gamma 1	0.048
Auts2	autism susceptibility candidate 2	0.046
Gata6	GATA binding protein 6	0.046
Gata3	GATA binding protein 3	0.046
Tcf21	transcription factor 21	0.042
Ephb2	Eph receptor B2	0.042
Tcf3	transcription factor 3	0.042
Dll1	delta-like 1 (Drosophila)	0.042
Zbtb20	zinc finger and BTB domain containing 20	0.040
Sox3	SRY-box containing gene 3	0.039
Hipk2	homeodomain interacting protein kinase 2	0.038
Dag1	dystroglycan 1	0.038
Tbx10	T-box 10	0.037
Trp53	transformation related protein 53	0.037
Mmp15	matrix metallopeptidase 15	0.036
Tcf4	transcription factor 4	0.036
Klf3	Kruppel-like factor 3 (basic)	0.035
Olig2	oligodendrocyte transcription factor 2	0.034	Mouse
Mkl2	MKL/myocardin-like 2	0.034
Fign	fidgetin	0.033
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.032
Zic2	zinc finger protein of the cerebellum 2	0.032
Zic1	zinc finger protein of the cerebellum 1	0.032
Rdh10	retinol dehydrogenase 10 (all-trans)	0.032
Pthlh	parathyroid hormone-like peptide	0.032
Ptms	parathymosin	0.032
Bmp2	bone morphogenetic protein 2	0.031
Prox1	prospero-related homeobox 1	0.031
Bmp1	bone morphogenetic protein 1	0.031
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.031
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.031
Irx5	Iroquois related homeobox 5 (Drosophila)	0.030
Ntf3	neurotrophin 3	0.030
Smad3	MAD homolog 3 (Drosophila)	0.029
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.029
Uncx	UNC homeobox	0.029
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.029
Neurod6	neurogenic differentiation 6	0.028
Ptf1a	pancreas specific transcription factor, 1a	0.028
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.027
Nfic	nuclear factor I/C	0.027	Mouse
Sall1	sal-like 1 (Drosophila)	0.027
Ddr2	discoidin domain receptor family, member 2	0.027
Alx1	ALX homeobox 1	0.026
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.026
Jup	junction plakoglobin	0.026
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.026
Wnt3	wingless-related MMTV integration site 3	0.025
Sall3	sal-like 3 (Drosophila)	0.025
Aes	amino-terminal enhancer of split	0.025
Hdac7	histone deacetylase 7	0.025
Lmna	lamin A	0.025
Lhx3	LIM homeobox protein 3	0.024
Hhip	Hedgehog-interacting protein	0.024
Phldb1	pleckstrin homology-like domain, family B, member 1	0.023
Neurod4	neurogenic differentiation 4	0.023
Ltbp3	latent transforming growth factor beta binding protein 3	0.023
Hoxb2	homeobox B2	0.023
Cntn2	contactin 2	0.023
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.022
Nes	nestin	0.022
Ret	ret proto-oncogene	0.021
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.021
Adcy9	adenylate cyclase 9	0.021
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.021
Onecut1	one cut domain, family member 1	0.021
Bmper	BMP-binding endothelial regulator	0.020
Pax1	paired box gene 1	0.020
Emp2	epithelial membrane protein 2	0.020
Hoxd11	homeobox D11	0.020
Hoxd3	homeobox D3	0.019
Pax7	paired box gene 7	0.019
Hoxc8	homeobox C8	0.019
Fgf17	fibroblast growth factor 17	0.019
Shox2	short stature homeobox 2	0.019
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.019
Sim2	single-minded homolog 2 (Drosophila)	0.019
Sox8	SRY-box containing gene 8	0.019
Pou4f1	POU domain, class 4, transcription factor 1	0.018
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.018
Zbtb16	zinc finger and BTB domain containing 16	0.018
Gpr50	G-protein-coupled receptor 50	0.018
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.018
Col11a1	collagen, type XI, alpha 1	0.018
Tbx15	T-box 15	0.018
Nkx2-1	NK2 homeobox 1	0.018
Onecut2	one cut domain, family member 2	0.018
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.018
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.017
Pax8	paired box gene 8	0.017
Plxnb1	plexin B1	0.017	Mouse
Mn1	meningioma 1	0.017
Spry2	sprouty homolog 2 (Drosophila)	0.017
Slc13a3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.017
Ebf2	early B-cell factor 2	0.017
Amhr2	anti-Mullerian hormone type 2 receptor	0.016
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.016
Foxa1	forkhead box A1	0.016
Trp63	transformation related protein 63	0.016
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.016
Ptprd	protein tyrosine phosphatase, receptor type, D	0.016
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.016
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.016
Plxna1	plexin A1	0.016	Mouse
Pdgfa	platelet derived growth factor, alpha	0.016
Zbtb12	zinc finger and BTB domain containing 12	0.016
Hes3	hairy and enhancer of split 3 (Drosophila)	0.016
Gja1	gap junction protein, alpha 1	0.015
Twist1	twist homolog 1 (Drosophila)	0.015
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.015
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.015
Pofut1	protein O-fucosyltransferase 1	0.014
Sox7	SRY-box containing gene 7	0.014
Nhlh1	nescient helix loop helix 1	0.014
Dll3	delta-like 3 (Drosophila)	0.014
Bnc1	basonuclin 1	0.014
Cachd1	cache domain containing 1	0.014
Hoxa10	homeobox A10	0.014
Zfp316	zinc finger protein 316	0.014
Neo1	neogenin	0.013
Kif1b	kinesin family member 1B	0.013
Nova1	neuro-oncological ventral antigen 1	0.013
Pkdcc	protein kinase domain containing, cytoplasmic	0.013
Fgfrl1	fibroblast growth factor receptor-like 1	0.013
Fgf3	fibroblast growth factor 3	0.013
Hmx2	H6 homeobox 2	0.013
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.013
Foxe3	forkhead box E3	0.013
Olig1	oligodendrocyte transcription factor 1	0.012	Mouse
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.012
Plxna3	plexin A3	0.012	Mouse
Apln	apelin	0.012
Sp8	trans-acting transcription factor 8	0.012
Arhgef40	Rho guanine nucleotide exchange factor (GEF) 40	0.012
Crygn	crystallin, gamma N	0.012
Hoxa11	homeobox A11	0.012
Npas3	neuronal PAS domain protein 3	0.012
Axin2	axin2	0.012
Irx3	Iroquois related homeobox 3 (Drosophila)	0.012
Foxi3	forkhead box I3	0.012
Ncoa1	nuclear receptor coactivator 1	0.012
Ncor2	nuclear receptor co-repressor 2	0.011
Hoxb3	homeobox B3	0.011
Nav1	neuron navigator 1	0.011
Cnpy1	canopy 1 homolog (zebrafish)	0.011
Zfp467	zinc finger protein 467	0.011
Mab21l2	mab-21-like 2 (C. elegans)	0.011
Mks1	Meckel syndrome, type 1	0.011
Gdnf	glial cell line derived neurotrophic factor	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Kank2	KN motif and ankyrin repeat domains 2	0.011
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
Zfp385a	zinc finger protein 385A	0.011
Foxd1	forkhead box D1	0.011
Tlx1	T-cell leukemia, homeobox 1	0.010
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.010
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.010
Crh	corticotropin releasing hormone	0.010
Wt1	Wilms tumor 1 homolog	0.010
Drd2	dopamine receptor D2	0.010
BC024139	cDNA sequence BC024139	0.010
Hoxb8	homeobox B8	0.010
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.010
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.010