IMP

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mesodermal cell fate specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of mesodermal cell fate specification" (in gray)

Name	Description	Probability	Func Analog Organism
lft2	lefty2	0.720
mespa	mesoderm posterior a	0.626	Mouse
pcdh8	protocadherin 8	0.552
vent	ventral expressed homeobox	0.547
lft1	lefty1	0.492
admp	anti-dorsalizing morphogenic protein	0.485
foxi1	forkhead box I1	0.482
tbx6	T-box gene 6	0.431
tbx16	T-box gene 16	0.402
sox17	SRY-box containing gene 17	0.379	Mouse
chd	chordin	0.375
bmp7a	bone morphogenetic protein 7a	0.363
foxa3	forkhead box A3	0.361
tbx20	T-box 20	0.334
flh	floating head	0.334
hnf1ba	HNF1 homeobox Ba	0.329
gata5	GATA-binding protein 5	0.297
foxd5	forkhead box D5	0.284
oep	one-eyed pinhead	0.276
eve1	even-skipped-like1	0.262
her7	hairy and enhancer of split related-7	0.258
gata6	GATA-binding protein 6	0.248
gata2a	GATA-binding protein 2a	0.236
has2	hyaluronan synthase 2	0.219
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.213
bon	bonnie and clyde	0.185
hhex	hematopoietically expressed homeobox	0.164
fzd10	frizzled homolog 10	0.161
ndr2	nodal-related 2	0.160
sox32	SRY-box containing gene 32	0.156	Mouse
tbx1	T-box 1	0.150
dharma	dharma	0.149
vox	ventral homeobox	0.146
mxtx2	mix-type homeobox gene 2	0.143
her5	hairy-related 5	0.139
fzd5	frizzled homolog 5	0.131
tal1	T-cell acute lymphocytic leukemia 1	0.131
msgn1	mesogenin 1	0.129
cdx4	caudal type homeo box transcription factor 4	0.125
klf2a	Kruppel-like factor 2a	0.123
ndr1	nodal-related 1	0.120
dkk1b	dickkopf 1b	0.119
znfl2a	zinc finger-like gene 2a	0.104
aplnrb	apelin receptor b	0.100
spns2	spinster homolog 2 (Drosophila)	0.089
isl1	islet1	0.088
og9x	OG9 homeobox gene	0.086
sp5l	Sp5 transcription factor-like	0.085
nkx2.2a	NK2 transcription factor related 2a	0.084
drl	draculin	0.083
ved	ventrally expressed dharma/bozozok antagonist	0.080
pou5f1	POU domain, class 5, transcription factor 1	0.076
mespb	mesoderm posterior b	0.075	Mouse
hmx4	H6 family homeobox 4	0.073
tll1	tolloid-like 1	0.070
tbx5a	T-box 5a	0.070
otx1a	orthodenticle homolog 1a	0.068
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.068
pax6b	paired box gene 6b	0.066
zgc:193933	zgc:193933	0.066
fgf10a	fibroblast growth factor 10a	0.065
gli1	GLI-Kruppel family member 1	0.065
alcamb	activated leukocyte cell adhesion molecule b	0.065
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.064
piwil2	piwi-like 2 (Drosophila)	0.063
rx3	retinal homeobox gene 3	0.063
tagln2	transgelin 2	0.061
nkx6.1	NK6 transcription factor related, locus 1 (Drosophila)	0.060
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.060
nog1	noggin 1	0.060
stat3	signal transduction and activation of transcription 3	0.059
cdx1a	caudal type homeo box transcription factor 1 a	0.058
nos1	nitric oxide synthase 1 (neuronal)	0.057
lhx5	LIM homeobox 5	0.057
spaw	southpaw	0.056
sesn1	sestrin 1	0.055
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.055
acvr1b	activin A receptor, type IB	0.055
fgf8a	fibroblast growth factor 8 a	0.055
foxb1.2	forkhead box B1.2	0.054
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.054
pitx2	paired-like homeodomain transcription factor 2	0.052
bmp4	bone morphogenetic protein 4	0.051
lhx1b	LIM homeobox 1b	0.050
lhx3	LIM homeobox 3	0.050
foxn4	forkhead box N4	0.049
fzd8b	frizzled homolog 8b	0.049
bmp2b	bone morphogenetic protein 2b	0.048
foxh1	forkhead box H1	0.048
fezf2	FEZ family zinc finger 2	0.046
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.044
vasa	vasa homolog	0.044
nr2e1	nuclear receptor subfamily 2, group E, member 1	0.044
alas2	aminolevulinate, delta-, synthetase 2	0.044
eomesa	eomesodermin homolog a	0.043
lypd6	LY6/PLAUR domain containing 6	0.043
lhx1a	LIM homeobox 1a	0.043
nkx1.2la	NK1 transcription factor related 2-like,a	0.043
neurod	neurogenic differentiation	0.042
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.041
hbbe3	hemoglobin beta embryonic-3	0.040
dbx1a	developing brain homeobox 1a	0.039
neurod4	neurogenic differentiation 4	0.039
tbx24	T-box 24	0.039
gbx1	gastrulation brain homeobox 1	0.038
nkx2.5	NK2 transcription factor related 5	0.038
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.038
gata4	GATA-binding protein 4	0.037
osr1	odd-skipped related 1 (Drosophila)	0.037
inab	internexin neuronal intermediate filament protein, alpha b	0.037
wnt4a	wingless-type MMTV integration site family, member 4a	0.037
hmx3	homeo box (H6 family) 3	0.037
pnx	posterior neuron-specific homeobox	0.036
cbfb	core-binding factor, beta subunit	0.036
prickle1a	prickle-like 1 (Drosophila) a	0.035
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.035
her1	hairy-related 1	0.035
mxtx1	mix-type homeobox gene 1	0.035
olfm2	olfactomedin 2	0.033
her3	hairy-related 3	0.033
eya1	eyes absent homolog 1	0.032
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.032
nkd2	naked cuticle homolog 2 and naked 2a	0.031
runx1	runt-related transcription factor 1	0.031
per3	period homolog 3 (Drosophila)	0.031
gata3	GATA-binding protein 3	0.030
gata1a	GATA binding protein 1a	0.030
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.030
atoh7	atonal homolog 7	0.030
brd4	bromodomain containing 4	0.030
grem2	gremlin 2, cysteine knot superfamily	0.030
ntla	no tail a	0.030
zgc:110712	zgc:110712	0.030
olig2	oligodendrocyte lineage transcription factor 2	0.030
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.029
dab1a	disabled homolog 1a (Drosophila)	0.029
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.028
six4b	sine oculis homeobox homolog 4b	0.028
sb:cb1008	sb:cb1008	0.027
blf	bloody fingers	0.027
tbx2b	T-box 2b	0.026
hoxd4a	homeo box D4a	0.026
met	met proto-oncogene (hepatocyte growth factor receptor)	0.026
hoxa11a	homeo box A11a	0.026
six4a	sine oculis homeobox homolog 4a	0.025
ripply2	ripply2	0.025
lmo2	LIM domain only 2 (rhombotin-like 1)	0.025
foxd3	forkhead box D3	0.025
ihhb	Indian hedgehog homolog b	0.024
notch1b	notch homolog 1b	0.024
stmn2a	stathmin-like 2a	0.024
irf6	interferon regulatory factor 6	0.024
spon1b	spondin 1b	0.024
flt4	fms-related tyrosine kinase 4	0.024
fgf17	fibroblast growth factor 17	0.024
fgf24	fibroblast growth factor 24	0.023
si:ch211-235f6.2	si:ch211-235f6.2	0.023
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.022
dmrt3a	doublesex and mab-3 related transcription factor 3a	0.022
aplnra	apelin receptor a	0.022
fzd8a	frizzled homolog 8a	0.021
mib	mind bomb	0.021
wnt11	wingless-type MMTV integration site family, member 11	0.021
nrarpb	notch-regulated ankyrin repeat protein b	0.021
rorb	RAR-related orphan receptor B	0.020
foxg1a	forkhead box G1a	0.020
tsc22d3	TSC22 domain family, member 3	0.020
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.020
pkd2	polycystic kidney disease 2	0.020
elk4	ELK4, ETS-domain protein	0.020
jag1b	jagged 1b	0.020
sox4b	SRY-box containing gene 4b	0.019
limk2	LIM domain kinase 2	0.019
mesp2	mesoderm posterior 2 homolog (mouse)	0.019
pax8	paired box gene 8	0.019
mnx1	motor neuron and pancreas homeobox 1	0.019
hand2	heart and neural crest derivatives expressed transcript 2	0.019
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.019
wnt8b	wingless-type MMTV integration site family, member 8b	0.019
wif1	wnt inhibitory factor 1	0.019
anxa5b	annexin A5b	0.019
wnt9a	wingless-type MMTV integration site family, member 9A	0.018
uros	uroporphyrinogen III synthase	0.018
wnt4b	wingless-type MMTV integration site family, member 4b	0.018
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.018
edn1	endothelin 1	0.018
coro2a	coronin, actin binding protein, 2A	0.018
gsc	goosecoid	0.018
gbx2	gastrulation brain homeo box 2	0.018
tpbgl	trophoblast glycoprotein-like	0.018
wnt5b	wingless-type MMTV integration site family, member 5b	0.018
thbs1	thrombospondin 1	0.017
ripply1	ripply1	0.017
rest	RE1-silencing transcription factor	0.017
hesx1	homeo box (expressed in ES cells) 1	0.017
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.017
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.017
rhov	ras homolog gene family, member V	0.017
nkx2.2b	NK2 transcription factor related 2b	0.017
rx2	retinal homeobox gene 2	0.017
si:dkeyp-113d7.7	si:dkeyp-113d7.7	0.017
ncam1a	neural cell adhesion molecule 1a	0.017
ctgf	connective tissue growth factor	0.017
bty	bloodthirsty	0.017
msxc	muscle segment homeobox C	0.017
sst1.1	somatostatin 1, tandem duplicate 1	0.017
actc1b	actin, alpha, cardiac muscle 1b	0.016
tbpl2	TATA box binding protein like 2	0.016
dlc	deltaC	0.016
gdf6b	growth differentiation factor 6b	0.016
hnf1a	HNF1 homeobox a	0.016
nrxn2a	neurexin 2a	0.016
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.016
cfl2l	cofilin 2, like	0.016
rxrga	retinoid x receptor, gamma a	0.016
bhlhe40	basic helix-loop-helix family, member e40	0.015
neurog1	neurogenin 1	0.015
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.015
wnt2	wingless-type MMTV integration site family member 2	0.015
gfap	glial fibrillary acidic protein	0.015
wnt1	wingless-type MMTV integration site family, member 1	0.015
prox1	prospero-related homeobox gene 1	0.015
pax2a	paired box gene 2a	0.015
ret1	receptor tyrosine kinase	0.015
tie1	endothelium-specific receptor tyrosine kinase 1	0.015
tp63	tumor protein p63	0.015
otpb	orthopedia homolog b	0.015
hbae3	hemoglobin alpha embryonic-3	0.015
inppl1a	inositol polyphosphate phosphatase-like 1a	0.015
shha	sonic hedgehog a	0.015
tdrd7	tudor domain containing 7	0.014
ltbp3	latent transforming growth factor beta binding protein 3	0.014
flot1	flotillin 1	0.014
cdh1	cadherin 1, epithelial	0.014
dla	deltaA	0.014
hnf4a	hepatocyte nuclear factor 4, alpha	0.014
LOC572344	hypothetical protein LOC572344	0.014
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.014
fgf3	fibroblast growth factor 3	0.014
eif4e1b	eukaryotic translation initiation factor 4e 1b	0.014
aqp1a.1	aquaporin 1a, tandem duplicate 1	0.014
wnt10b	wingless-type MMTV integration site family, member 10b	0.014
hbbe2	hemoglobin beta embryonic-2	0.014
hoxb8a	homeo box B8a	0.014
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.014
pax6a	paired box gene 6a	0.014
dcn	decorin	0.014
furina	furin (paired basic amino acid cleaving enzyme) a	0.014
dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.013
tph1b	tryptophan hydroxylase 1b	0.013
efna5a	ephrin A5a	0.013
nanos3	nanos homolog 3	0.013
fn1	fibronectin 1	0.013
dscam	Down syndrome cell adhesion molecule	0.013
perp	PERP, TP53 apoptosis effector	0.013
hlxb9la	homeo box HB9 like a	0.013
pou2f1a	POU class 2 homeobox 1a	0.013
irx3a	iroquois homeobox protein 3a	0.013
sox10	SRY-box containing gene 10	0.013
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.012
rasl11b	RAS-like, family 11, member B	0.012
sox2	SRY-box containing gene 2	0.012
ext1a	exostoses (multiple) 1a	0.012
ins	preproinsulin	0.012
insb	preproinsulin b	0.012
lnx2b	ligand of numb-protein X 2b	0.012
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.012
frzb	frizzled-related protein	0.012
ek1	eph-like kinase 1	0.012
hoxc6a	homeo box C6a	0.012
notch1a	notch homolog 1a	0.012
tnw	tenascin W	0.012
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.012
hoxd12a	homeo box D12a	0.012
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.012
bmper	BMP binding endothelial regulator	0.012
myl7	myosin, light polypeptide 7, regulatory	0.012
slc17a6a	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a	0.012
tjp1	tight junction protein 1 (zona occludens 1)	0.012
vim	vimentin	0.012
vmhc	ventricular myosin heavy chain	0.012
fli1a	friend leukemia integration 1a	0.012
klf4	Kruppel-like factor 4	0.012	Zebrafish
trim33	tripartite motif-containing 33	0.012
igf1	insulin-like growth factor 1	0.012
frem3	Fras1 related extracellular matrix 3	0.012
nkx2.1b	NK2 homeobox 1b	0.012
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.011
vax2	ventral anterior homeobox 2	0.011
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.011
cntn1a	contactin 1a	0.011
fech	ferrochelatase	0.011
zgc:153997	zgc:153997	0.011
slc20a1a	solute carrier family 20, member 1a	0.011
dbx1b	developing brain homeobox 1b	0.011
dlx4b	distal-less homeobox gene 4b	0.011
pmp22b	peripheral myelin protein 22b	0.011
ntn1a	netrin 1a	0.011
lfng	lunatic fringe homolog	0.011
rad21	RAD21 homolog (S. pombe)	0.011
ptch1	patched 1	0.011
anxa1b	annexin A1b	0.011
hoxc1a	homeo box C1a	0.011
mkks	McKusick-Kaufman syndrome	0.011
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.011
irx4a	iroquois homeobox protein 4a	0.011
nkx2.1a	NK2 homeobox 1a	0.011
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.011
sox19b	SRY-box containing gene 19b	0.011
ptprb	protein tyrosine phosphatase, receptor type, b	0.011
sfrp1a	secreted frizzled-related protein 1a	0.011
col1a2	collagen, type I, alpha 2	0.011
hoxc8a	homeo box C8a	0.011
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.010
sox7	SRY-box containing gene 7	0.010
irx7	iroquois homeobox protein 7	0.010
fbn2b	fibrillin 2b	0.010
ncam1b	neural cell adhesion molecule 1b	0.010
hgfa	hepatocyte growth factor a	0.010
gcga	glucagon a and glucagon a-like	0.010
gpc4	glypican 4	0.010
etv2	ets variant gene 2	0.010
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.010
ogg1	8-oxoguanine DNA glycosylase	0.010
ca15b	carbonic anhydrase XV b	0.010
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.010
wu:fc24e06	wu:fc24e06	0.010
ehd2	EH-domain containing 2	0.010
dusp5	dual specificity phosphatase 5	0.010