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Danio rerio

2 genes annotated in zebrafish

collagen biosynthetic process

The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "collagen biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "collagen biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
col1a1a	collagen, type I, alpha 1a	0.987	Human
col5a1	procollagen, type V, alpha 1	0.929	Human
col1a2	collagen, type I, alpha 2	0.893
sparc	secreted acidic cysteine rich glycoprotein	0.680
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.466	Worm
hapln1a	hyaluronan and proteoglycan link protein 1a	0.422
bmp2b	bone morphogenetic protein 2b	0.418
foxj1a	forkhead box J1a	0.334
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.279	Worm
col2a1a	collagen type II, alpha-1a	0.202
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.200
tcf12	transcription factor 12	0.184
il6st	interleukin 6 signal transducer	0.178
col11a1a	collagen, type XI, alpha 1a	0.174
zgc:85866	zgc:85866	0.168
fbn2b	fibrillin 2b	0.162
chsy1	chondroitin sulfate synthase 1	0.161
cav1	caveolin 1	0.154
gata5	GATA-binding protein 5	0.142
osr1	odd-skipped related 1 (Drosophila)	0.141
dlx5a	distal-less homeobox gene 5a	0.139
ctgf	connective tissue growth factor	0.137	Rat
col10a1	collagen, type X, alpha 1	0.134
postn	periostin, osteoblast specific factor	0.126
jag1b	jagged 1b	0.090
col11a1b	collagen type XI alpha-1b and collagen, type XI, alpha 1b	0.088
col27a1a	collagen, type XXVII, alpha 1a	0.087
tpm4	tropomyosin 4	0.082
bmp1a	bone morphogenetic protein 1a	0.082
LOC565459	tight junction protein ZO-1-like	0.078
igf2b	insulin-like growth factor 2b	0.077
duox	dual oxidase	0.076
arl13b	ADP-ribosylation factor-like 13b	0.067
matn4	matrilin 4	0.061
col1a1b	collagen, type I, alpha 1b	0.061	Human
zgc:63947	zgc:63947	0.060
agr2	anterior gradient homolog 2 (Xenopus laevis)	0.059
cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.058
col5a2l	collagen, type V, alpha 2-like	0.056
sepw1	selenoprotein W, 1	0.056
pthlh	parathyroid hormone-like hormone	0.054
frzb	frizzled-related protein	0.053
foxa3	forkhead box A3	0.052
LOC100334210	growth/differentiation factor 5-like	0.050
mtp	microsomal triglyceride transfer protein	0.048
ahr2	aryl hydrocarbon receptor 2	0.048
spry4	sprouty (Drosophila) homolog 4	0.047
si:ch211-173b8.2	si:ch211-173b8.2	0.045
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.045
jun	jun proto-oncogene	0.043
sdprb	serum deprivation response b	0.043
prdm1a	PR domain containing 1a, with ZNF domain	0.042
fgf10a	fibroblast growth factor 10a	0.041
tgfb2	transforming growth factor, beta 2	0.041
map1lc3a	microtubule-associated protein 1 light chain 3 alpha	0.040
plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.039	Worm
col6a2	collagen, type VI, alpha 2	0.039
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.039
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.038
vcanb	versican b	0.038
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.038
fgf20a	fibroblast growth factor 20a	0.037
twist2	twist2	0.037
pmp22b	peripheral myelin protein 22b	0.036
vgll4l	vestigial like 4 like	0.035
tppp3	tubulin polymerization-promoting protein family member 3	0.034
LOC569128	hypothetical protein LOC569128	0.034
hsp47	heat shock protein 47	0.033	Mouse
si:dkey-151c10.1	si:dkey-151c10.1	0.033
wnt11r	wingless-type MMTV integration site family, member 11, related	0.033
col6a3	collagen, type VI, alpha 3	0.033
zgc:56419	zgc:56419	0.032
pfkfb4l	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, like	0.031
dcn	decorin	0.031
col27a1b	collagen, type XXVII, alpha 1b	0.030
wu:fv91b12	wu:fv91b12	0.030
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.029
itgb1b	integrin, beta 1b	0.029
fxyd1	FXYD domain containing ion transport regulator 1 (phospholemman)	0.029
surf4l	surfeit gene 4, like	0.028
rnasel1	ribonuclease like 1	0.028
zgc:171553	zgc:171553	0.027
zgc:111821	zgc:111821	0.027
notch2	notch homolog 2	0.027
cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.027
si:dkey-76k16.7	si:dkey-76k16.7	0.027
cpa5	carboxypeptidase A5	0.027
chpf	chondroitin polymerizing factor	0.026
wif1	wnt inhibitory factor 1	0.026
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.026
csnk1a1	casein kinase 1, alpha 1	0.026
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.026
papss2b	3'-phosphoadenosine 5'-phosphosulfate synthase 2b	0.025
gata6	GATA-binding protein 6	0.025
cdx1b	caudal type homeobox 1 b	0.025
ptpreb	protein tyrosine phosphatase, receptor type, E, b	0.025
sox9a	SRY-box containing gene 9a	0.024
bhlhe41	basic helix-loop-helix family, member e41	0.024
aqp1a.1	aquaporin 1a, tandem duplicate 1	0.024
zgc:92411	zgc:92411	0.024
col8a1a	collagen, type VIII, alpha 1a	0.024
klf2b	Kruppel-like factor 2b	0.023
gcm2	glial cells missing homolog 2 (Drosophila)	0.023
serpina1l	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like	0.023
epor	erythropoietin receptor	0.023
ptch1	patched 1	0.023
gyltl1b	glycosyltransferase-like 1b	0.023
crtap	cartilage associated protein	0.022
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.022
anxa1a	annexin A1a	0.022
id:ibd2573	id:ibd2573	0.022
col12a1	collagen, type XII, alpha 1	0.022
slc38a3	solute carrier family 38, member 3	0.022
aplnrb	apelin receptor b	0.022
ehd2	EH-domain containing 2	0.022
mkxa	mohawk homeobox a	0.022
gpx4b	glutathione peroxidase 4b	0.021
rhoaa	ras homolog gene family, member Aa	0.021
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.021
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.021
pax9	paired box gene 9	0.021
epyc	epiphycan	0.021
sp7	Sp7 transcription factor	0.020
p4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2	0.020
arrdc3a	arrestin domain containing 3a	0.020
atp5h	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d	0.020
snai1a	snail homolog 1a (Drosophila)	0.020
sh3gl1b	SH3-domain GRB2-like 1b	0.020
hspa5	heat shock protein 5	0.020
hmcn1	hemicentin 1	0.020
c8a	complement component 8, alpha polypeptide	0.020
icn	ictacalcin	0.020
zgc:162630	zgc:162630	0.020
zgc:123180	zgc:123180	0.019
mc5rb	melanocortin 5b receptor	0.019
si:dkeyp-68f6.1	si:dkeyp-68f6.1	0.019
dsc2l	desmocollin 2 like	0.019
il1b	interleukin 1, beta and interleukin 1, beta	0.019
kitlgb	kit ligand b	0.019
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.018
hdac4	histone deacetylase 4	0.018
smad9	MAD homolog 9 (Drosophila)	0.018
asph	aspartate beta-hydroxylase	0.018
calrl	calreticulin like	0.018
ptch2	patched 2	0.018
tbx2a	T-box gene 2a	0.018
carm1	coactivator-associated arginine methyltransferase 1	0.018
cfdl	complement factor D (adipsin) like	0.018
sec31a	sec31 homolog A (S. cerevisiae)	0.018
pgrmc1	progesterone receptor membrane component 1	0.018
si:dkey-25o1.2	si:dkey-25o1.2	0.018
angptl2	angiopoietin-like 2	0.017
angptl7	angiopoietin-like 7	0.017
frem3	Fras1 related extracellular matrix 3	0.017
ggcx	gamma-glutamyl carboxylase	0.017
fn1b	fibronectin 1b	0.017
lrp2	low density lipoprotein-related protein 2	0.017
grhprb	glyoxylate reductase/hydroxypyruvate reductase b	0.017
slc17a9b	solute carrier family 17, member 9b	0.017
zgc:153700	zgc:153700	0.017
im:7136220	im:7136220	0.017
tcea2	transcription elongation factor A (SII), 2	0.016
rrbp1	ribosome binding protein 1 homolog (dog)	0.016
brp44	brain protein 44	0.016
rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.016
scinlb	scinderin like b	0.016
ntd5	ntl-dependent gene 5	0.016
glcci1	glucocorticoid induced transcript 1	0.016
kiss1	KiSS-1 metastasis-suppressor	0.016
fgfrl1a	fibroblast growth factor receptor-like 1a	0.016
gpc4	glypican 4	0.016
tdh	L-threonine dehydrogenase	0.016
enpep	glutamyl aminopeptidase	0.016
naca	nascent polypeptide-associated complex alpha polypeptide	0.016
im:6911434	im:6911434	0.016
flnbl	filamin B, like	0.016
satb2	SATB homeobox 2	0.016
a1cf	apobec1 complementation factor	0.015
capn2b	calpain 2, (m/II) large subunit b	0.015
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.015
ip6k2	inositol hexaphosphate kinase 2	0.015
zgc:77744	zgc:77744	0.015
LOC564872	monocarboxylate transporter 7-like	0.015
gstal	glutathione S-transferase, alpha-like	0.015
itga3b	integrin, alpha 3b	0.015
crfb5	cytokine receptor family member b5	0.015
ncoa1	nuclear receptor coactivator 1	0.015
zgc:91930	zgc:91930	0.015
ssr4	signal sequence receptor, delta	0.014
col9a2	procollagen, type IX, alpha 2	0.014
etnk1	ethanolamine kinase 1	0.014
slc1a4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	0.014
cald1	caldesmon 1	0.014
eif4ebp3l	eukaryotic translation initiation factor 4E binding protein 3, like	0.014
lamb1a	laminin, beta 1a	0.014
ntla	no tail a	0.014
loxl3b	lysyl oxidase-like 3b	0.014
si:rp71-1g18.9	si:rp71-1g18.9	0.014
nkx3-1	NK3 homeobox 1	0.014
pkd2	polycystic kidney disease 2	0.014
si:xx-bac7cse.2	si:xx-bac7cse.2	0.014
adrb2a	adrenergic receptor, beta 2a	0.014
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.014
glrbb	glycine receptor, beta b	0.014
il8	interleukin 8	0.014
smchd1	structural maintenance of chromosomes flexible hinge domain containing 1	0.014
emilin3a	elastin microfibril interfacer 3a	0.014
junb	jun B proto-oncogene	0.014
card14	caspase recruitment domain family, member 14	0.014
fxyd6l	FXYD domain containing ion transport regulator 6 like	0.014
capns1a	calpain, small subunit 1 a	0.014
slc34a2b	solute carrier family 34 (sodium phosphate), member 2b	0.014
tsku	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.013
nadka	NAD kinase a	0.013
zgc:101540	zgc:101540	0.013
spon2a	spondin 2a, extracellular matrix protein	0.013
zgc:158603	zgc:158603	0.013
creld2	cysteine-rich with EGF-like domains 2	0.013
crebbpa	CREB binding protein a	0.013
itgb1a	integrin, beta 1a	0.013
kctd15a	potassium channel tetramerisation domain containing 15a	0.013
stc1l	stanniocalcin 1, like	0.013
bon	bonnie and clyde	0.013
zgc:103440	zgc:103440	0.013
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.013
echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.013
aqp3a	aquaporin 3a	0.013
dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.013
si:ch211-237l4.5	si:ch211-237l4.5	0.013
foxf1	forkhead box F1	0.013
chmp5	chromatin modifying protein 5	0.012
zgc:194470	zgc:194470	0.012
si:dkey-6n6.4	si:dkey-6n6.4	0.012
col4a3	collagen, type IV, alpha 3	0.012
fzd7a	frizzled homolog 7a	0.012
zgc:103715	zgc:103715	0.012
ltbp3	latent transforming growth factor beta binding protein 3	0.012
adora2aa	adenosine A2a receptor a	0.012
adi1	acireductone dioxygenase 1	0.012
zgc:65890	zgc:65890	0.012
nr1i2	nuclear receptor subfamily 1, group I, member 2	0.012
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.012
acta1a	actin, alpha 1a, skeletal muscle	0.012
LOC556849	ectonucleoside triphosphate diphosphohydrolase 5-like	0.012
fam46ba	family with sequence similarity 46, member Ba	0.012
fstl1b	follistatin-like 1b	0.012
ildr1b	immunoglobulin-like domain containing receptor 1b	0.012
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.012
fabp11b	fatty acid binding protein 11b	0.012
pacrg	PARK2 co-regulated	0.012
bmp16	bone morphogenetic protein 16	0.012
sec61g	Sec61 gamma subunit	0.012
sec24d	SEC24 family, member D (S. cerevisiae)	0.012
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.012
bmp3	bone morphogenetic protein 3	0.012
ctsk	cathepsin K	0.012
pparda	peroxisome proliferator-activated receptor delta a	0.012	Rat
cbsb	cystathionine-beta-synthase b	0.012
anxa13	annexin A13	0.012
atp2a1l	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like	0.012
st3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	0.012
tlr8b	toll-like receptor 8b	0.012
rassf1	Ras association (RalGDS/AF-6) domain family 1	0.012
cldni	claudin i	0.012
ins	preproinsulin	0.012
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.012
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.012
lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.012
blf	bloody fingers	0.012
col4a2	collagen, type IV, alpha 2	0.012
golgb1	golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1	0.012
barx2	BarH-like homeobox 2	0.012
serpinf1	serine (or cysteine) peptidase inhibitor, clade F, member 1	0.012
acaa1	acetyl-Coenzyme A acyltransferase 1	0.012
pdia2	protein disulfide isomerase family A, member 2	0.012
col19a1	collagen, type XIX, alpha 1	0.012
pdip5	protein disulfide isomerase-related protein (provisional)	0.012
dhrs9	dehydrogenase/reductase (SDR family) member 9	0.012
spi1l	spleen focus forming virus (SFFV) proviral integration oncogene spi1 like	0.012
barx1	BarH-like homeobox 1	0.012
ext1b	exostoses (multiple) 1b	0.012
ptprea	protein tyrosine phosphatase, receptor type, E, a	0.012
si:ch73-73d17.3	si:ch73-73d17.3	0.012
zgc:103671	zgc:103671	0.012
fbln2	fibulin 2	0.012
aco1	aconitase 1, soluble	0.012
zgc:92533	zgc:92533	0.012
mmp14b	matrix metalloproteinase 14b (membrane-inserted)	0.011
LOC100000500	sclerostin-like	0.011
tgfbi	transforming growth factor, beta-induced	0.011
usp39	ubiquitin specific peptidase 39	0.011
rasl11b	RAS-like, family 11, member B	0.011
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.011
thbs4b	thrombospondin 4b	0.011
egfl7	EGF-like-domain, multiple 7	0.011
cxcl14	chemokine (C-X-C motif) ligand 14	0.011
bhlhe40	basic helix-loop-helix family, member e40	0.011
sgpl1	sphingosine-1-phosphate lyase 1	0.011
zgc:103585	zgc:103585	0.011
mmp2	matrix metalloproteinase 2	0.011
sfrp1b	secreted frizzled-related protein 1b	0.011
id1	inhibitor of DNA binding 1	0.011
timp2a	tissue inhibitor of metalloproteinase 2a	0.011
zgc:92480	zgc:92480	0.011
slc25a12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	0.011
si:dkeyp-117b8.3	si:dkeyp-117b8.3	0.011
mxc	myxovirus (influenza virus) resistance C	0.011
fkbp3	FK506 binding protein 3	0.011
zgc:171494	zgc:171494	0.011
adrb1	adrenergic receptor, beta 1	0.011
lta4h	leukotriene A4 hydrolase	0.011
cetn2	centrin, EF-hand protein, 2	0.011
xylt1	xylosyltransferase 1	0.011
scpp1	secretory calcium-binding phosphoprotein 1	0.011
ednra	endothelin receptor type A	0.011
idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.011
tram1	translocating chain-associating membrane protein 1	0.011
coro2a	coronin, actin binding protein, 2A	0.011
fynb	FYN oncogene related to SRC, FGR, YES b	0.011
atf6	activating transcription factor 6	0.011
rhof	ras homolog gene family, member F	0.011
sulf1	sulfatase 1	0.011
cnpy4	canopy4	0.011
acana	aggrecan a	0.011
esd	esterase D/formylglutathione hydrolase	0.011
sb:eu1555	sb:eu1555	0.011
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.011
tfe3a	transcription factor binding to IGHM enhancer 3a	0.011
mfi2	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	0.011
vtnb	vitronectin b	0.011
prdm14	PR domain containing 14	0.011
ccdc80	coiled-coil domain containing 80	0.011
zgc:91909	zgc:91909	0.011
cnpy2	canopy 2	0.011
lama1	laminin, alpha 1	0.011
cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.010
zgc:91944	zgc:91944	0.010
ltv1	LTV1 homolog (S. cerevisiae)	0.010
krt15	keratin 15	0.010
fgfrl1b	fibroblast growth factor receptor-like 1b	0.010
LOC100003911	chemokine CXCL-C13d	0.010
xbp1	X-box binding protein 1	0.010
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.010
si:ch73-6k14.1	si:ch73-6k14.1	0.010
cetp	cholesteryl ester transfer protein, plasma	0.010
inhbb	inhibin, beta B	0.010
fscn1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.010
lhcgr	luteinizing hormone/choriogonadotropin receptor	0.010
angptl1	angiopoietin-like 1	0.010
mfsd2aa	major facilitator superfamily domain containing 2aa	0.010
tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.010
si:ch211-15d5.5	si:ch211-15d5.5	0.010
thbs1	thrombospondin 1	0.010
fam18b	family with sequence similarity 18, member B	0.010
gfer	growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)	0.010
zgc:64161	zgc:64161	0.010
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.010
zgc:64040	zgc:64040	0.010
keap1b	kelch-like ECH-associated protein 1b	0.010