IMP

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Danio rerio

15 genes annotated in zebrafish

regulation of kinase activity

Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of kinase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
wnt1	wingless-type MMTV integration site family, member 1	0.423	Zebrafish
flh	floating head	0.195
pea3	ETS-domain transcription factor pea3	0.190
crip2	cysteine-rich protein 2	0.149
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.144
dag1	dystroglycan 1	0.119
sfrp1a	secreted frizzled-related protein 1a	0.107	Mouse
fzd7a	frizzled homolog 7a	0.096
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.096
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.089	Human
dusp6	dual specificity phosphatase 6	0.088	Human
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.086
psen1	presenilin 1	0.086	Mouse
dkk1b	dickkopf 1b	0.081
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.078	Human Mouse
robo3	roundabout homolog 3	0.074
pdgfaa	platelet-derived growth factor alpha a	0.063	Human
zbtb4	zinc finger and BTB domain containing 4	0.060
rnd3a	Rho family GTPase 3a	0.060
igf1ra	insulin-like growth factor 1a receptor	0.057	Human
epha4a	eph receptor A4a	0.053
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.052
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.051	Human
btg2	B-cell translocation gene 2	0.051
epas1b	endothelial PAS domain protein 1b	0.051
dlc	deltaC	0.050
wnt10a	wingless-type MMTV integration site family, member 10a	0.050	Zebrafish
smad9	MAD homolog 9 (Drosophila)	0.049
spry4	sprouty (Drosophila) homolog 4	0.047	Mouse
axin2	axin 2 (conductin, axil)	0.046	Zebrafish Rat
igf1rb	insulin-like growth factor 1b receptor	0.045	Human
ved	ventrally expressed dharma/bozozok antagonist	0.045
fgf3	fibroblast growth factor 3	0.044
ccnb1	cyclin B1	0.043	Yeast Worm Fly
si:dkey-8l13.4	si:dkey-8l13.4	0.041
foxa2	forkhead box A2	0.041	Mouse
rhoab	ras homolog gene family, member Ab	0.038
cdc25	cell division cycle 25 homolog	0.038	Mouse
pak2a	p21 (CDKN1A)-activated kinase 2a	0.038	Human Yeast
arl4ab	ADP-ribosylation factor-like 4ab	0.038
shha	sonic hedgehog a	0.038
dab1b	disabled homolog 1b (Drosophila)	0.037
il17rd	interleukin 17 receptor D	0.036
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.036	Fly
gro2	groucho 2	0.036
igf2b	insulin-like growth factor 2b	0.035	Mouse
ptpra	protein tyrosine phosphatase, receptor type, A	0.034
ptena	phosphatase and tensin homolog A	0.034	Human
tlr3	toll-like receptor 3	0.034
socs1	suppressor of cytokine signaling 1	0.034	Mouse
gadd45bb	growth arrest and DNA-damage-inducible, beta b	0.034	Human Mouse
nf1a	neurofibromin 1a	0.034	Mouse
wls	wntless homolog (Drosophila)	0.034
neo1	neogenin 1	0.033
mpped2	metallophosphoesterase domain containing 2	0.033
vegfaa	vascular endothelial growth factor Aa	0.032
foxi1	forkhead box I1	0.032
fgf17	fibroblast growth factor 17	0.032
LOC566708	FL cytokine receptor-like	0.031
socs3a	suppressor of cytokine signaling 3a	0.030
sox11a	SRY-box containing gene 11a	0.030
gro1	groucho 1	0.030
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.029
cd63	Cd63 antigen	0.029
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.029
tgfb3	transforming growth factor, beta 3	0.029	Rat
wnt8b	wingless-type MMTV integration site family, member 8b	0.029	Zebrafish
ccna2	cyclin A2	0.028
jag2	jagged 2	0.027
hspa4a	heat shock protein 4a	0.026
rap1a	RAP1A, member of RAS oncogene family	0.026
pak1	p21/Cdc42/Rac1-activated kinase 1	0.026
mt2	metallothionein 2	0.026
mapk14a	mitogen-activated protein kinase 14a	0.026
frzb	frizzled-related protein	0.026
egr2b	early growth response 2b	0.026	Worm
sox2	SRY-box containing gene 2	0.026
si:dkeyp-22b2.3	si:dkeyp-22b2.3	0.025
pth2	parathyroid hormone 2	0.025
nsa2	NSA2 ribosome biogenesis homolog (S. cerevisiae)	0.025
mbtps1	membrane-bound transcription factor protease, site 1	0.024
ndrg1	N-myc downstream regulated gene 1	0.024
nppa	natriuretic peptide precursor A	0.023
mmp9	matrix metalloproteinase 9	0.023
kirrel3l	kin of IRRE like 3 like	0.023
sgk1	serum/glucocorticoid regulated kinase 1	0.023
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.023
id1	inhibitor of DNA binding 1	0.023
ccnd1	cyclin D1	0.023	Human Mouse Fly
smad7	MAD, mothers against decapentaplegic homolog 7 (Drosophila)	0.022
ghra	growth hormone receptor a	0.022	Rat
rarab	retinoic acid receptor, alpha b	0.022
wt1b	wilms tumor 1b	0.022
fgf20a	fibroblast growth factor 20a	0.022
lama5	laminin, alpha 5	0.022
sp2	sp2 transcription factor	0.021
bmp2b	bone morphogenetic protein 2b	0.021	Human
msi1	musashi homolog 1 (Drosophila)	0.021
bnc2	basonuclin 2	0.021
her6	hairy-related 6	0.021	Zebrafish
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.021
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.021
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.020
id3	inhibitor of DNA binding 3	0.020
hhip	hedgehog interacting protein	0.020
bmp2a	bone morphogenetic protein 2a	0.020	Human
csnk1g2a	casein kinase 1, gamma 2a	0.020
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.020	Zebrafish Rat
si:ch211-173o4.2	si:ch211-173o4.2	0.020
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.020
myca	myelocytomatosis oncogene a	0.019
her15.1	hairy and enhancer of split-related 15.1	0.019	Zebrafish
wnt4a	wingless-type MMTV integration site family, member 4a	0.019	Zebrafish
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.019
LOC100151531	zinc finger protein Gfi-1b-like	0.019
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.019
acp5b	acid phosphatase 5b, tartrate resistant	0.019
foxj1a	forkhead box J1a	0.019
mapk1	mitogen-activated protein kinase 1	0.019
col11a1b	collagen type XI alpha-1b and collagen, type XI, alpha 1b	0.019
csnk1da	casein kinase 1, delta a	0.019
prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.019
fbp1b	fructose-1,6-bisphosphatase 1b	0.019
nanos3	nanos homolog 3	0.019
fzd10	frizzled homolog 10	0.018	Human
wnt11r	wingless-type MMTV integration site family, member 11, related	0.018	Zebrafish
fgfr4	fibroblast growth factor receptor 4	0.018	Fly
pou5f1	POU domain, class 5, transcription factor 1	0.018
efnb2a	ephrin B2a	0.018
per3	period homolog 3 (Drosophila)	0.018
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.018
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.018	Zebrafish
ndr1	nodal-related 1	0.018
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.018	Human
ptk2.1	protein tyrosine kinase 2a	0.017	Human Fly
cdh1	cadherin 1, epithelial	0.017
sox3	SRY-box containing gene 3	0.017
pias4a	protein inhibitor of activated STAT, 4a	0.017
notch3	notch homolog 3	0.017
etv5b	ets variant 5b	0.017
hoxa13a	homeo box A13a	0.017
sox11b	SRY-box containing gene 11b	0.017
twist1a	twist1a	0.017
zgc:85866	zgc:85866	0.017	Human
sall1a	sal-like 1a (Drosophila)	0.017
mstnb	myostatin b	0.016
adka	adenosine kinase a	0.016
erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog	0.016	Human
junb	jun B proto-oncogene	0.016
spry2	sprouty homolog 2	0.016
jun	jun proto-oncogene	0.016
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.016
gbx1	gastrulation brain homeobox 1	0.016
hsp90a.2	heat shock protein 90-alpha 2	0.016
gnat1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.016
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.016
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.016
si:ch211-195h23.3	si:ch211-195h23.3	0.016
irak4	interleukin-1 receptor-associated kinase 4	0.016
igf1	insulin-like growth factor 1	0.016
notch2	notch homolog 2	0.016
rcv1	recoverin	0.015
her9	hairy-related 9	0.015	Zebrafish
tagln2	transgelin 2	0.015
prdx2	peroxiredoxin 2	0.015	Mouse
atp1a3b	ATPase, Na+/K+ transporting, alpha 3b polypeptide	0.015
traf4a	tnf receptor-associated factor 4a	0.015
zmat2	zinc finger, matrin type 2	0.015
csrnp1b	cysteine-serine-rich nuclear protein 1b	0.015
si:ch211-57k11.10	si:ch211-57k11.10	0.015
numbl	numb homolog (Drosophila)-like	0.015
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.015
acvr2a	activin receptor IIa	0.015
junbl	jun B proto-oncogene, like	0.015
igfbp7	insulin-like growth factor binding protein 7	0.015
wnt3	wingless-type MMTV integration site family, member 3	0.015	Zebrafish
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.014
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.014
mif	macrophage migration inhibitory factor	0.014	Mouse
pomca	proopiomelanocortin a	0.014
lfng	lunatic fringe homolog	0.014
smad1	MAD homolog 1 (Drosophila)	0.014
si:dkeyp-50f5.1	si:dkeyp-50f5.1	0.014
dnaja	DnaJ (Hsp40) homolog, subfamily A member	0.014
foxo3a	forkhead box O3A	0.014
ephb4b	eph receptor B4b	0.014
zgc:91930	zgc:91930	0.013
cap1	Cap1 CAP, adenylate cyclase-associated protein 1	0.013
metrn	meteorin, glial cell differentiation regulator	0.013
ahsa1l	AHA1, activator of heat shock protein ATPase homolog 1, like	0.013
nf1b	neurofibromin 1b	0.013	Mouse
her3	hairy-related 3	0.013
rbp4l	retinol binding protein 4, like	0.013
notch1a	notch homolog 1a	0.013
spna2	spectrin alpha 2	0.013
ryk	receptor-like tyrosine kinase	0.013
htra1a	HtrA serine peptidase 1a	0.013
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.013
gadd45g	growth arrest and DNA-damage-inducible, gamma	0.013	Human Mouse
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.013
mbnl2	muscleblind-like 2 (Drosophila)	0.013
card9	caspase recruitment domain family, member 9	0.013
snai1a	snail homolog 1a (Drosophila)	0.013
cldn5a	claudin 5a	0.013
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.013
nr2e3	nuclear receptor subfamily 2, group E, member 3	0.013
her1	hairy-related 1	0.013
avpl	arginine vasopressin-like	0.013
si:ch73-9j13.1	si:ch73-9j13.1	0.013	Fly
skp1	S-phase kinase-associated protein 1	0.013
hgfb	hepatocyte growth factor b	0.013
etv5a	ets variant 5a	0.013
tph2	tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)	0.013
lcp1	lymphocyte cytosolic plastin 1	0.012
csad	cysteine sulfinic acid decarboxylase	0.012
tcf12	transcription factor 12	0.012
col7a1l	collagen type VII alpha 1-like	0.012
egfra	epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	0.012	Human
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.012	Human Rat
dvl2	dishevelled, dsh homolog 2 (Drosophila)	0.012	Human Mouse
gbx2	gastrulation brain homeo box 2	0.012
hk1	hexokinase 1	0.012
emilin1a	elastin microfibril interfacer 1a	0.012
map3k4	mitogen activated protein kinase kinase kinase 4	0.012	Human Mouse Fly
adora2b	adenosine A2b receptor	0.012
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.012
ehd1	EH-domain containing 1	0.012
tfec	transcription factor EC	0.012
gpr126	G protein-coupled receptor 126	0.012
zgc:92851	zgc:92851	0.012
fas	Fas (TNF receptor superfamily, member 6)	0.012
aldob	aldolase b, fructose-bisphosphate	0.012
piwil1	piwi-like 1 (Drosophila)	0.012
fn1b	fibronectin 1b	0.012
six4.3	sine oculis homeobox homolog 4.3	0.012
gfap	glial fibrillary acidic protein	0.012
ctgf	connective tissue growth factor	0.012
dnmt7	DNA (cytosine-5-)-methyltransferase 7	0.012
zgc:55813	zgc:55813	0.011
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.011
fgfr1a	fibroblast growth factor receptor 1a	0.011	Human Fly
nfe2l2	nuclear factor (erythroid-derived 2)-like 2	0.011
gli1	GLI-Kruppel family member 1	0.011
si:dkey-27i16.2	si:dkey-27i16.2	0.011
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.011
dusp2	dual specificity phosphatase 2	0.011
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.011
wu:fb58e05	wu:fb58e05	0.011
wnt16	wingless-type MMTV integration site family, member 16	0.011
sox32	SRY-box containing gene 32	0.011
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
ghrb	growth hormone receptor b	0.011	Rat
mef2a	myocyte enhancer factor 2a	0.011
hsp70l	heat shock cognate 70-kd protein, like	0.011
crx	cone-rod homeobox	0.011
copa	coatomer protein complex, subunit alpha	0.011
cldne	claudin e	0.011
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.011
rap1b	RAS related protein 1b	0.011	Rat
jak2a	Janus kinase 2a	0.011
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.011
lims1	LIM and senescent cell antigen-like domains 1	0.011
map2k4b	mitogen-activated protein kinase kinase 4b	0.011
nrp2a	neuropilin 2a	0.011
ca15b	carbonic anhydrase XV b	0.011
vipr2	vasoactive intestinal peptide receptor 2	0.011
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.011
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.011
bglap	bone gamma-carboxyglutamate (gla) protein	0.011
fgfr3	fibroblast growth factor receptor 3	0.011	Human Fly
bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.010
LOC567678	avidin-like	0.010
osr2	odd-skipped related 2 (Drosophila)	0.010
sulf1	sulfatase 1	0.010
lrrtm1	leucine rich repeat transmembrane neuronal 1	0.010
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.010
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.010
ccnb2	cyclin B2	0.010	Yeast Worm Fly
odc1	ornithine decarboxylase 1	0.010
dab2	disabled homolog 2 (Drosophila)	0.010	Mouse
rbm22	RNA binding motif protein 22	0.010
si:ch211-212m21.5	si:ch211-212m21.5	0.010
znfl2a	zinc finger-like gene 2a	0.010
appa	amyloid beta (A4) precursor protein a	0.010	Mouse
zgc:100919	zgc:100919	0.010
tbx2b	T-box 2b	0.010
stmn1a	stathmin 1a	0.010
kbp	kif1-binding protein	0.010
wnt3a	wingless-type MMTV integration site family, member 3A	0.010	Zebrafish Mouse