The network for 'anterior posterior axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

anterior posterior axis specification

The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.998
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.994
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.990
JUN jun proto-oncogene 0.979
SMAD3 SMAD family member 3 0.969
OCRL oculocerebrorenal syndrome of Lowe 0.950
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.948
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.934
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.918
ZYX zyxin 0.904
FN1 fibronectin 1 0.902
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.894
PRKCZ protein kinase C, zeta 0.888
TP53 tumor protein p53 0.886
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.885
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.880
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.878
ANAPC7 anaphase promoting complex subunit 7 0.873
EIF4A3 eukaryotic translation initiation factor 4A3 0.838
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.834
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.823
CUL2 cullin 2 0.819
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.818
SCHIP1 schwannomin interacting protein 1 0.805
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.787
SMAD2 SMAD family member 2 0.779
NCF2 neutrophil cytosolic factor 2 0.776
ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.768
GDA guanine deaminase 0.766
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.765
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.732
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.698
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.696
APC adenomatous polyposis coli 0.693
MAP2K1 mitogen-activated protein kinase kinase 1 0.683
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.673
BMP1 bone morphogenetic protein 1 0.669
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.664
USP11 ubiquitin specific peptidase 11 0.661
SFN stratifin 0.660
HMGA1 high mobility group AT-hook 1 0.657
NXF1 nuclear RNA export factor 1 0.654
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.650
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.638
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.626
PALB2 partner and localizer of BRCA2 0.621
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.621
TACC3 transforming, acidic coiled-coil containing protein 3 0.617
CHRD chordin 0.593
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.592
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.585
CARM1 coactivator-associated arginine methyltransferase 1 0.578
C19orf39 chromosome 19 open reading frame 39 0.574
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.566
CBX8 chromobox homolog 8 0.559
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.558
FBLN1 fibulin 1 0.558
YBX1 Y box binding protein 1 0.556
RAD51L1 RAD51-like 1 (S. cerevisiae) 0.554
GSK3B glycogen synthase kinase 3 beta 0.550
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.536
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.531
SET SET nuclear oncogene 0.525
MDC1 mediator of DNA-damage checkpoint 1 0.520
ZFYVE9 zinc finger, FYVE domain containing 9 0.516
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.497
VHL von Hippel-Lindau tumor suppressor 0.479
HSPA8 heat shock 70kDa protein 8 0.472
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.472
WNT3A wingless-type MMTV integration site family, member 3A 0.470
PRKCI protein kinase C, iota 0.464
XIAP X-linked inhibitor of apoptosis 0.461
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.447
SMAD4 SMAD family member 4 0.443
RBL2 retinoblastoma-like 2 (p130) 0.439
KEAP1 kelch-like ECH-associated protein 1 0.433
SH3RF3 SH3 domain containing ring finger 3 0.432
BRCA2 breast cancer 2, early onset 0.429
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.429
CDC25B cell division cycle 25 homolog B (S. pombe) 0.426
ZFX zinc finger protein, X-linked 0.424
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.419
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.417
ACTN1 actinin, alpha 1 0.417
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.415
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.415
ANAPC5 anaphase promoting complex subunit 5 0.411
PICALM phosphatidylinositol binding clathrin assembly protein 0.399
DCP1A DCP1 decapping enzyme homolog A (S. cerevisiae) 0.397
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.396
CDC20 cell division cycle 20 homolog (S. cerevisiae) 0.390
SNAP25 synaptosomal-associated protein, 25kDa 0.379
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.373
ADAM17 ADAM metallopeptidase domain 17 0.372
CD44 CD44 molecule (Indian blood group) 0.369
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.369
CUL1 cullin 1 0.366
AXIN1 axin 1 0.363
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.801
nhr-25 Protein NHR-25 0.334
let-60 Protein LET-60 0.326
Y47D3A.29 Protein Y47D3A.29 0.260
snr-4 Protein SNR-4 0.198
arx-7 Protein ARX-7 0.180
mpk-1 Protein MPK-1 0.174
chk-1 Protein CHK-1 0.160
wrm-1 Protein WRM-1 0.112
zyg-9 Protein ZYG-9 0.112
mcm-2 Protein MCM-2 0.089
lin-45 Protein LIN-45 0.087
ztf-22 Protein ZTF-22 0.085
cul-2 Protein CUL-2 0.079
mab-5 Protein MAB-5 0.077
par-2 Protein PAR-2 0.075
pgl-1 Protein PGL-1 0.074
grd-1 Protein GRD-1 0.074
cwn-1 Protein CWN-1 0.071
pry-1 Protein PRY-1 0.064
egl-18 Protein EGL-18 0.063
unc-43 Protein UNC-43 0.062
tra-1 Protein TRA-1 0.060
spc-1 Protein SPC-1 0.060
glh-1 Protein GLH-1 0.059
unc-62 Protein UNC-62 0.054
tap-1 Protein TAP-1 0.053
F13B6.1 Protein F13B6.1 0.049
svh-2 Protein SVH-2 0.047
snr-3 Protein SNR-3 0.047
glh-2 Protein GLH-2 0.047
glp-1 Protein GLP-1 0.045
syd-2 Protein SYD-2 0.044
prg-2 Protein PRG-2 0.042
goa-1 Protein GOA-1 0.042
tbg-1 Protein TBG-1 0.042
elc-1 Protein ELC-1 0.041
C17H11.6 Protein C17H11.6 0.040
rig-6 Protein RIG-6 0.040
hpo-32 Protein HPO-32 0.039
ast-1 Protein AST-1 0.039
cki-1 Protein CKI-1 0.039
mac-1 Protein MAC-1 0.038
chd-7 Protein CHD-7 0.037
ani-1 Protein ANI-1 0.037
hid-1 Protein HID-1 0.036
egl-46 Protein EGL-46 0.036
C45G9.6 Protein C45G9.6 0.035
ina-1 Protein INA-1 0.035
sma-6 Protein SMA-6 0.035
lin-3 Protein LIN-3 0.035
pas-3 Protein PAS-3 0.034
W03F8.4 Protein W03F8.4 0.034
fem-1 Protein FEM-1 0.034
CELE_C01G10.8 Protein C01G10.8 0.034
prg-1 Protein PRG-1 0.034
rskn-1 Protein RSKN-1 0.031
unc-98 Protein UNC-98 0.030
gpb-1 Protein GPB-1 0.029
par-3 Protein PAR-3 0.029
xpo-1 Protein XPO-1 0.028
unc-73 Protein UNC-73 0.028
clec-180 Protein CLEC-180 0.028
rars-1 Protein RARS-1 0.027
ucr-2.3 Protein UCR-2.3 0.027
ajm-1 Protein AJM-1 0.026
gsk-3 Protein GSK-3 0.026
zyg-11 Protein ZYG-11 0.026
bar-1 Protein BAR-1 0.026
ceh-20 Protein CEH-20 0.026
CELE_E01G4.6 Protein E01G4.6 0.025
klp-15 Protein KLP-15 0.025
cec-9 Protein CEC-9 0.025
hlh-30 Protein HLH-30 0.025
csc-1 Protein CSC-1 0.025
CELE_C38D4.9 Protein C38D4.9 0.024
xpo-2 Protein XPO-2 0.024
CELE_C17H12.13 Protein C17H12.13 0.023
pyc-1 Protein PYC-1 0.023
pqn-89 Protein PQN-89 0.023
plx-2 Protein PLX-2 0.023
C50B8.1 Protein C50B8.1 0.023
par-1 Protein PAR-1 0.023
glh-4 Protein GLH-4 0.023
R12E2.1 Protein R12E2.1 0.023
T04B8.5 Protein T04B8.5 0.023
zer-1 Protein ZER-1 0.023
cdh-3 Protein CDH-3 0.023
thoc-2 Protein THOC-2 0.022
Y43H11AL.1 Protein Y43H11AL.1 0.022
retr-1 Protein RETR-1 0.022
cec-1 Protein CEC-1 0.022
cyn-13 Protein CYN-13 0.022
F11E6.7 Protein F11E6.7 0.021
ain-1 Protein AIN-1 0.020
F36D4.5 Protein F36D4.5 0.020
ugt-50 Protein UGT-50 0.020
msh-6 Protein MSH-6 0.020
lit-1 Protein LIT-1 0.020
ubxn-2 Protein UBXN-2 0.020
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Danio rerio
Name Description Probability Func Analog Organism
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.893
ndr2 nodal-related 2 0.688
lef1 lymphocyte enhancer binding factor 1 0.619
dld deltaD 0.600
nanos3 nanos homolog 3 0.593
wnt11 wingless-type MMTV integration site family, member 11 0.584
mespa mesoderm posterior a 0.459
ca15b carbonic anhydrase XV b 0.399
ntla no tail a 0.392
six4b sine oculis homeobox homolog 4b 0.390
prickle1a prickle-like 1 (Drosophila) a 0.320
oep one-eyed pinhead 0.302
pcdh8 protocadherin 8 0.295
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.289
rarab retinoic acid receptor, alpha b 0.287
chd chordin 0.260
cdh2 cadherin 2, neuronal 0.239
bmp4 bone morphogenetic protein 4 0.234
lft1 lefty1 0.231
tbx16 T-box gene 16 0.221
her7 hairy and enhancer of split related-7 0.220
dla deltaA 0.210
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.206
sox19b SRY-box containing gene 19b 0.191
dazl daz-like gene 0.181
emx3 empty spiracles homeobox 3 0.179
ccnb1 cyclin B1 0.175
flh floating head 0.166
tll1 tolloid-like 1 0.158
org oogenesis-related gene 0.153
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.152
tbx20 T-box 20 0.151
brca2 breast cancer 2, early onset 0.148
sp5l Sp5 transcription factor-like 0.143
neo1 neogenin 1 0.142
fezf2 FEZ family zinc finger 2 0.136
tpbgl trophoblast glycoprotein-like 0.132
ripply2 ripply2 0.131
etv2 ets variant gene 2 0.129
foxi1 forkhead box I1 0.127
her3 hairy-related 3 0.126
tbx6 T-box gene 6 0.123
lhx1a LIM homeobox 1a 0.122
her1 hairy-related 1 0.120
ripply1 ripply1 0.111
pou5f1 POU domain, class 5, transcription factor 1 0.109
zic5 zic family member 5 (odd-paired homolog, Drosophila) 0.108
tbx1 T-box 1 0.107
pglyrp2 peptidoglycan recognition protein 2 0.106
lft2 lefty2 0.105
has2 hyaluronan synthase 2 0.102
pkd2 polycystic kidney disease 2 0.101
runx1 runt-related transcription factor 1 0.101
aplnrb apelin receptor b 0.100
hoxb1b homeo box B1b 0.099
fzd10 frizzled homolog 10 0.092
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.091
pnx posterior neuron-specific homeobox 0.090
otx1b orthodenticle homolog 1b 0.089
foxb1.1 forkhead box B1.1 0.088
piwil2 piwi-like 2 (Drosophila) 0.088
acvr1l activin A receptor, type I like 0.085
nkd2 naked cuticle homolog 2 and naked 2a 0.085
bmp2b bone morphogenetic protein 2b 0.084
gyltl1b glycosyltransferase-like 1b 0.081
mespb mesoderm posterior b 0.081
spaw southpaw 0.079
acvr1b activin A receptor, type IB 0.078
nog1 noggin 1 0.077
prkcz protein kinase C, zeta 0.076
rest RE1-silencing transcription factor 0.071
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.071
eve1 even-skipped-like1 0.071
alcamb activated leukocyte cell adhesion molecule b 0.071
pfn2 profilin 2 0.069
sox2 SRY-box containing gene 2 0.068
eya1 eyes absent homolog 1 0.066
gbx1 gastrulation brain homeobox 1 0.066
rx3 retinal homeobox gene 3 0.064
axin1 axin 1 0.064
wnt8a wingless-type MMTV integration site family, member 8a 0.063
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.062
zgc:195154 zgc:195154 0.062
notch3 notch homolog 3 0.062
dag1 dystroglycan 1 0.060
dlg2 discs, large (Drosophila) homolog 2 0.060
irx7 iroquois homeobox protein 7 0.060
e2f5 E2F transcription factor 5 0.058
cdx4 caudal type homeo box transcription factor 4 0.057
hoxa13a homeo box A13a 0.056
shha sonic hedgehog a 0.056
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.053
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.051
cbfb core-binding factor, beta subunit 0.051
crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.049
snx1 sorting nexin 1 0.049
spsb4a splA/ryanodine receptor domain and SOCS box containing 4a 0.048
pea3 ETS-domain transcription factor pea3 0.047
spsb1 splA/ryanodine receptor domain and SOCS box containing 1 0.047
fzd7a frizzled homolog 7a 0.046
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Drosophila melanogaster
Name Description Probability Func Analog Organism
arm armadillo 0.997
brat brain tumor 0.990
sqd squid 0.982
phl pole hole 0.980
vls valois 0.966
orb oo18 RNA-binding protein 0.961
osk oskar 0.958
eya eyes absent 0.922
bcd bicoid 0.922
Dcp1 Decapping protein 1 0.916
stau staufen 0.911
tral trailer hitch 0.910
aret arrest 0.901
tkv thickveins 0.887
BicD Bicaudal D 0.887
mago mago nashi 0.877
sax saxophone 0.865
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.865
cact cactus 0.857
par-6 CG5884 gene product from transcript CG5884-RA 0.850
vas vasa 0.842
spir spire 0.836
baz bazooka 0.827
aPKC atypical protein kinase C 0.822
Egfr Epidermal growth factor receptor 0.818
shg shotgun 0.818
pum pumilio 0.815
hb hunchback 0.795
ci cubitus interruptus 0.792
fs(1)M3 female sterile (1) M3 0.782
pita CG3941 gene product from transcript CG3941-RA 0.770
glo glorund 0.762
Brca2 Breast cancer 2, early onset homolog 0.716
dpp decapentaplegic 0.710
Dlic Dynein light intermediate chain 0.704
psq pipsqueak 0.700
spn-E spindle E 0.682
Lam Lamin 0.672
trk trunk 0.665
egh egghead 0.636
ksr kinase suppressor of ras 0.624
Fas2 Fasciclin 2 0.602
sec5 CG8843 gene product from transcript CG8843-RA 0.571
Src64B Src oncogene at 64B 0.566
argos CG4531 gene product from transcript CG4531-RA 0.560
trc tricornered 0.551
run runt 0.516
Ser Serrate 0.509
okr okra 0.505
par-1 CG8201 gene product from transcript CG8201-RA 0.500
exu exuperantia 0.494
RpII140 RNA polymerase II 140kD subunit 0.490
ovo CG6824 gene product from transcript CG6824-RE 0.489
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.448
fj four-jointed 0.442
Ras85D Ras oncogene at 85D 0.438
spen split ends 0.435
sd scalloped 0.408
gus gustavus 0.394
mirr mirror 0.394
grk gurken 0.381
Btk29A Btk family kinase at 29A 0.381
Kr Kruppel 0.372
ari-1 ariadne 0.371
Hel25E Helicase at 25E 0.364
salm spalt major 0.362
NetB Netrin-B 0.355
spn-A spindle A 0.353
ftz fushi tarazu 0.327
Myd88 CG2078 gene product from transcript CG2078-RA 0.319
aub aubergine 0.318
Gprk2 G protein-coupled receptor kinase 2 0.297
gt giant 0.293
spn-B spindle B 0.287
rok Rho-kinase 0.286
Dp DP transcription factor 0.284
Trl Trithorax-like 0.283
os outstretched 0.278
ecd ecdysoneless 0.277
Rac1 CG2248 gene product from transcript CG2248-RA 0.263
Abi Abelson interacting protein 0.262
ptc patched 0.261
egg eggless 0.260
ens ensconsin 0.260
LanA Laminin A 0.258
crb crumbs 0.254
CG4771 CG4771 gene product from transcript CG4771-RA 0.254
mus301 mutagen-sensitive 301 0.248
Wnt4 Wnt oncogene analog 4 0.248
jagn jagunal 0.246
spn-F CG12114 gene product from transcript CG12114-RA 0.244
tho2 CG31671 gene product from transcript CG31671-RA 0.242
srp serpent 0.237
gbb glass bottom boat 0.234
VAChT CG32848 gene product from transcript CG32848-RA 0.233
fog folded gastrulation 0.227
Rho1 CG8416 gene product from transcript CG8416-RB 0.225
dsh dishevelled 0.224
dac dachshund 0.224
CG10260 CG10260 gene product from transcript CG10260-RB 0.222
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism