The network for 'muscle cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

muscle cell proliferation

The expansion of a muscle cell population by cell division.

Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
FGFR2 fibroblast growth factor receptor 2 1.000
ESR1 estrogen receptor 1 0.999
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.999
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.998
TEK TEK tyrosine kinase, endothelial 0.998
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.998
RARA retinoic acid receptor, alpha 0.997
IL6 interleukin 6 (interferon, beta 2) 0.996
RXRA retinoid X receptor, alpha 0.986
CDK2 cyclin-dependent kinase 2 0.979
TBX5 T-box 5 0.974
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.970
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.970
FGF1 fibroblast growth factor 1 (acidic) 0.965
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.963
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.960
EP300 E1A binding protein p300 0.954
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.945
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.942
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.941
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.934
CCL2 chemokine (C-C motif) ligand 2 0.932
C1QA complement component 1, q subcomponent, A chain 0.929
NRP1 neuropilin 1 0.913
JAG1 jagged 1 0.901
CCL4 chemokine (C-C motif) ligand 4 0.898
AR androgen receptor 0.864
IGF2 insulin-like growth factor 2 (somatomedin A) 0.833
FGFR1 fibroblast growth factor receptor 1 0.825
CXCL2 chemokine (C-X-C motif) ligand 2 0.823
GRB7 growth factor receptor-bound protein 7 0.803
IL8 interleukin 8 0.798
CCR5 chemokine (C-C motif) receptor 5 0.778
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.763
NOSTRIN nitric oxide synthase trafficker 0.723
TRAF6 TNF receptor-associated factor 6 0.719
NCOA1 nuclear receptor coactivator 1 0.696
TGFB3 transforming growth factor, beta 3 0.673
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.659
CDH5 cadherin 5, type 2 (vascular endothelium) 0.657
THBS1 thrombospondin 1 0.651
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.645
PPARG peroxisome proliferator-activated receptor gamma 0.634
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.622
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.583
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.566
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.539
TBXA2R thromboxane A2 receptor 0.525
DCN decorin 0.523
ENG endoglin 0.514
EPAS1 endothelial PAS domain protein 1 0.512
C3 complement component 3 0.501
CXCL9 chemokine (C-X-C motif) ligand 9 0.500
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.488
FSTL1 follistatin-like 1 0.481
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.471
BMP2 bone morphogenetic protein 2 0.459
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.454
ANG angiogenin, ribonuclease, RNase A family, 5 0.425
CCL5 chemokine (C-C motif) ligand 5 0.421
C1QC complement component 1, q subcomponent, C chain 0.409
CXCL3 chemokine (C-X-C motif) ligand 3 0.398
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.396
CREBBP CREB binding protein 0.394
SIRT1 sirtuin 1 0.389
RNASE4 ribonuclease, RNase A family, 4 0.384
DSG2 desmoglein 2 0.358
HNF4A hepatocyte nuclear factor 4, alpha 0.350
NCOA3 nuclear receptor coactivator 3 0.347
FGF10 fibroblast growth factor 10 0.344
DDR2 discoidin domain receptor tyrosine kinase 2 0.343
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.342
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.336
YAP1 Yes-associated protein 1 0.327
NCOR2 nuclear receptor corepressor 2 0.319
BMPR1A bone morphogenetic protein receptor, type IA 0.298
CXCL12 chemokine (C-X-C motif) ligand 12 0.297
CCL8 chemokine (C-C motif) ligand 8 0.295
SPOP speckle-type POZ protein 0.291
FBLN1 fibulin 1 0.287
PGF placental growth factor 0.278
PDGFA platelet-derived growth factor alpha polypeptide 0.266
FGF7 fibroblast growth factor 7 0.263
FBXW11 F-box and WD repeat domain containing 11 0.258
CD34 CD34 molecule 0.256
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.256
TCF4 transcription factor 4 0.254
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.253
INSR insulin receptor 0.241
IGFBP5 insulin-like growth factor binding protein 5 0.240
IL1B interleukin 1, beta 0.229
PELI3 pellino homolog 3 (Drosophila) 0.224
HDAC1 histone deacetylase 1 0.218
PSEN1 presenilin 1 0.218
PLCG1 phospholipase C, gamma 1 0.217
IL23A interleukin 23, alpha subunit p19 0.214
IL2RB interleukin 2 receptor, beta 0.210
CXCL10 chemokine (C-X-C motif) ligand 10 0.200
MED25 mediator complex subunit 25 0.198
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.092
nkx3.2 NK3 homeobox 2 0.092
myod1 myogenic differentiation 1 0.048
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.040
gli1 GLI-Kruppel family member 1 0.032
nkx2.2b NK2 transcription factor related 2b 0.025
cdh2 cadherin 2, neuronal 0.021
nkx2.2a NK2 transcription factor related 2a 0.020
fabp11a fatty acid binding protein 11a 0.020
unc5b unc-5 homolog B (C. elegans) 0.019
flt4 fms-related tyrosine kinase 4 0.016
nkx2.5 NK2 transcription factor related 5 0.015
fgf4 fibroblast growth factor 4 0.014
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.013
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.013
twist1a twist1a 0.012
hoxa13b homeo box A13b 0.012
tbx20 T-box 20 0.012
pax6a paired box gene 6a 0.011
six4b sine oculis homeobox homolog 4b 0.011
shhb sonic hedgehog b 0.011
fgf8a fibroblast growth factor 8 a 0.011
nog2 noggin 2 0.011
rbpms2 RNA binding protein with multiple splicing 2 0.010
flot1 flotillin 1 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.998
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.992
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.987
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.983
Ctnnb1 catenin (cadherin associated protein), beta 1 0.982
Prrx1 paired related homeobox 1 0.977
Lepr leptin receptor 0.977
Fgfr2 fibroblast growth factor receptor 2 0.973
Hand2 heart and neural crest derivatives expressed transcript 2 0.969
Fgf8 fibroblast growth factor 8 0.968
Gata4 GATA binding protein 4 0.967
Foxc1 forkhead box C1 0.966
Gli2 GLI-Kruppel family member GLI2 0.965
Sox9 SRY-box containing gene 9 0.953
Smad3 MAD homolog 3 (Drosophila) 0.952
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.945
Foxc2 forkhead box C2 0.940
Nos3 nitric oxide synthase 3, endothelial cell 0.934
Nog noggin 0.909
Eya1 eyes absent 1 homolog (Drosophila) 0.908
Gli3 GLI-Kruppel family member GLI3 0.881
Pthlh parathyroid hormone-like peptide 0.878
Fgfr3 fibroblast growth factor receptor 3 0.872
Fgfr1 fibroblast growth factor receptor 1 0.872
Hoxa1 homeobox A1 0.830
Pax3 paired box gene 3 0.828
Tgfb2 transforming growth factor, beta 2 0.825
Pten phosphatase and tensin homolog 0.810
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.798
Tbx3 T-box 3 0.793
Chrd chordin 0.791
Csf1 colony stimulating factor 1 (macrophage) 0.755
Pax2 paired box gene 2 0.754
Foxa2 forkhead box A2 0.748
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.747
Ntf3 neurotrophin 3 0.730
Zfpm2 zinc finger protein, multitype 2 0.709
Hand1 heart and neural crest derivatives expressed transcript 1 0.708
Wnt10b wingless related MMTV integration site 10b 0.678
Bmp2 bone morphogenetic protein 2 0.670
Amhr2 anti-Mullerian hormone type 2 receptor 0.664
Bmp4 bone morphogenetic protein 4 0.657
Bcl2 B-cell leukemia/lymphoma 2 0.652
Tbx2 T-box 2 0.642
Pax8 paired box gene 8 0.636
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.635
Efnb2 ephrin B2 0.628
Gsc goosecoid homeobox 0.609
Apc adenomatosis polyposis coli 0.594
Jag1 jagged 1 0.588
Acvr1 activin A receptor, type 1 0.587
Ar androgen receptor 0.586
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.584
Bdnf brain derived neurotrophic factor 0.580
Esr2 estrogen receptor 2 (beta) 0.557
Gdnf glial cell line derived neurotrophic factor 0.555
Flt4 FMS-like tyrosine kinase 4 0.553
Tgfbr2 transforming growth factor, beta receptor II 0.548
Tcf4 transcription factor 4 0.543
Tbx5 T-box 5 0.520
Runx2 runt related transcription factor 2 0.520
Notch1 Notch gene homolog 1 (Drosophila) 0.516
Gdf5 growth differentiation factor 5 0.511
Hoxa13 homeobox A13 0.503
Wnt3a wingless-related MMTV integration site 3A 0.501
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.499
Smo smoothened homolog (Drosophila) 0.485
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.484
Gata6 GATA binding protein 6 0.475
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.471
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.466
Ptgs2 prostaglandin-endoperoxide synthase 2 0.457
Zeb1 zinc finger E-box binding homeobox 1 0.449
Fgf10 fibroblast growth factor 10 0.446
Wnt2b wingless related MMTV integration site 2b 0.443
Smad1 MAD homolog 1 (Drosophila) 0.440
Dll4 delta-like 4 (Drosophila) 0.413
Smad4 MAD homolog 4 (Drosophila) 0.398
Pou3f3 POU domain, class 3, transcription factor 3 0.397
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.397
Msx1 homeobox, msh-like 1 0.396
Hmx3 H6 homeobox 3 0.395
Dlx5 distal-less homeobox 5 0.361
Tbx1 T-box 1 0.359
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.350
Lmx1a LIM homeobox transcription factor 1 alpha 0.350
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.350
Col1a1 collagen, type I, alpha 1 0.341
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.340
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.334
Kdr kinase insert domain protein receptor 0.332
Notch2 Notch gene homolog 2 (Drosophila) 0.321
Pdx1 pancreatic and duodenal homeobox 1 0.320
Il10 interleukin 10 0.312
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.310
Pitx2 paired-like homeodomain transcription factor 2 0.306
Traf6 TNF receptor-associated factor 6 0.305
Smad6 MAD homolog 6 (Drosophila) 0.303
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.294
Twist2 twist homolog 2 (Drosophila) 0.292
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Flt1 FMS-related tyrosine kinase 1 0.614
Phkg1 phosphorylase kinase, gamma 1 0.438
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.281
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.264
Tgfbr2 transforming growth factor, beta receptor II 0.244
Ednra endothelin receptor type A 0.227
Clic4 chloride intracellular channel 4 0.223
Nrg1 neuregulin 1 0.217
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.216
Car5a carbonic anhydrase 5a, mitochondrial 0.205
Smad7 SMAD family member 7 0.203
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.196
Itga6 integrin, alpha 6 0.195
Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.183
Smad1 SMAD family member 1 0.181
Lims1 LIM and senescent cell antigen-like domains 1 0.176
Cmklr1 chemokine-like receptor 1 0.176
Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 0.176
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.172
Apoa5 apolipoprotein A-V 0.169
A2m alpha-2-macroglobulin 0.168
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.155
Gpr116 G protein-coupled receptor 116 0.155
Timp3 TIMP metallopeptidase inhibitor 3 0.153
Icam2 intercellular adhesion molecule 2 0.143
Ahsg alpha-2-HS-glycoprotein 0.139
Trib1 tribbles homolog 1 (Drosophila) 0.138
Gper G protein-coupled estrogen receptor 1 0.134
Alb albumin 0.134
Ucn urocortin 0.132
Akr1d1 aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) 0.131
Dmd dystrophin 0.128
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.126
Hist1h1a histone cluster 1, H1a 0.122
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.121
Cpxm2 carboxypeptidase X (M14 family), member 2 0.120
Socs3 suppressor of cytokine signaling 3 0.118
Itgam integrin, alpha M 0.116
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.116
Stat6 signal transducer and activator of transcription 6 0.113
Ednrb endothelin receptor type B 0.111
Robo1 roundabout homolog 1 (Drosophila) 0.111
Myo1c myosin IC 0.111
Elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.109
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.109
Kitlg KIT ligand 0.108
Irs1 insulin receptor substrate 1 0.107
Ptgfr prostaglandin F receptor 0.107
Testin testin gene 0.106
Megf6 multiple EGF-like-domains 6 0.106
Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 0.106
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.103
Tgfbr3 transforming growth factor, beta receptor III 0.103
Ctsj cathepsin J 0.103
Podxl podocalyxin-like 0.098
Nos1 nitric oxide synthase 1, neuronal 0.098
Thbd thrombomodulin 0.098
Rxra retinoid X receptor alpha 0.097
Ncr1 natural cytotoxicity triggering receptor 1 0.097
LOC100362824 caveolin 2-like 0.095
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.094
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.093
Egfr epidermal growth factor receptor 0.093
Jak1 Janus kinase 1 0.092
Gja5 gap junction protein, alpha 5 0.091
Bcl2 B-cell CLL/lymphoma 2 0.089
Sirpa signal-regulatory protein alpha 0.088
Rara retinoic acid receptor, alpha 0.087
LOC100360403 ATP-binding cassette, sub-family C, member 9-like 0.086
Smad3 SMAD family member 3 0.084
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.083
Aspn asporin 0.082
RT1-Ba RT1 class II, locus Ba 0.082
Rgs14 regulator of G-protein signaling 14 0.082
Dchs1 dachsous 1 (Drosophila) 0.080
Notch3 Notch homolog 3 (Drosophila) 0.080
Adrb1 adrenergic, beta-1-, receptor 0.078
RT1-M5 RT1 class Ib, locus M5 0.077
Utrn utrophin 0.075
Gas7 growth arrest specific 7 0.074
Olr837 olfactory receptor 837 0.074
Elf1 E74-like factor 1 0.073
Agtr1a angiotensin II receptor, type 1a 0.073
Ncf1 neutrophil cytosolic factor 1 0.072
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.071
Nos3 nitric oxide synthase 3, endothelial cell 0.071
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.071
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.070
Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.070
St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.069
RGD1561143 similar to cell surface receptor FDFACT 0.069
Ccnd3 cyclin D3 0.068
Grb2 growth factor receptor bound protein 2 0.068
Igfals insulin-like growth factor binding protein, acid labile subunit 0.068
Il9r interleukin 9 receptor 0.068
Fgf1 fibroblast growth factor 1 0.067
Cdkn3 cyclin-dependent kinase inhibitor 3 0.066
Adam9 ADAM metallopeptidase domain 9 (meltrin gamma) 0.066
Hrg histidine-rich glycoprotein 0.064
Foxd3 forkhead box D3 0.064
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism