The network for 'regulation of t cell costimulation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of t cell costimulation

Any process that modulates the frequency, rate or extent of T cell costimulation.

Name Description Probability Func Analog Organism
Ccr2 chemokine (C-C motif) receptor 2 0.980
Ccr6 chemokine (C-C motif) receptor 6 0.820
Ccr1 chemokine (C-C motif) receptor 1 0.780
Ccl3 chemokine (C-C motif) ligand 3 0.731
Cd44 CD44 antigen 0.723
Il10 interleukin 10 0.701
Ikzf1 IKAROS family zinc finger 1 0.689
Ccl2 chemokine (C-C motif) ligand 2 0.670
Cd7 CD7 antigen 0.660
Ccr5 chemokine (C-C motif) receptor 5 0.653
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.627
Xcr1 chemokine (C motif) receptor 1 0.627
Prdm1 PR domain containing 1, with ZNF domain 0.607
Itgax integrin alpha X 0.567
Fcrla Fc receptor-like A 0.554
Blk B lymphoid kinase 0.552
Cd180 CD180 antigen 0.548
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.488
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.473
Selp selectin, platelet 0.465
Ifng interferon gamma 0.456
Itgal integrin alpha L 0.401
Ncr1 natural cytotoxicity triggering receptor 1 0.340
Lta lymphotoxin A 0.289
Il18rap interleukin 18 receptor accessory protein 0.289
Icos inducible T-cell co-stimulator 0.272
H2-Ob histocompatibility 2, O region beta locus 0.237
Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide 0.228
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.220
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.210
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.207
Il18r1 interleukin 18 receptor 1 0.199
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.199
Cxcl13 chemokine (C-X-C motif) ligand 13 0.195
Fasl Fas ligand (TNF superfamily, member 6) 0.186
Cd96 CD96 antigen 0.178
Tlr4 toll-like receptor 4 0.177
Ccl4 chemokine (C-C motif) ligand 4 0.168
Ciita class II transactivator 0.164
Tnf tumor necrosis factor 0.163
Gpr132 G protein-coupled receptor 132 0.161
Gzmk granzyme K 0.161
LOC100502924 hypothetical protein LOC100502924 0.160
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.157
Tlr2 toll-like receptor 2 0.156
Itk IL2-inducible T-cell kinase 0.155
Cxcr3 chemokine (C-X-C motif) receptor 3 0.154
Mmp9 matrix metallopeptidase 9 0.150
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.141
Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 0.139
Il12rb2 interleukin 12 receptor, beta 2 0.135
Cd40 CD40 antigen 0.128
Il1b interleukin 1 beta 0.121
Sh2d2a SH2 domain protein 2A 0.119
Klra5 killer cell lectin-like receptor, subfamily A, member 5 0.116
Slamf1 signaling lymphocytic activation molecule family member 1 0.115
Cd22 CD22 antigen 0.111
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.110
Gcet2 germinal center expressed transcript 2 0.109
Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 0.108
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.107
Sell selectin, lymphocyte 0.107
Gzma granzyme A 0.106
Tlr7 toll-like receptor 7 0.106
Cxcr2 chemokine (C-X-C motif) receptor 2 0.103
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.102
Xcl1 chemokine (C motif) ligand 1 0.101
Art2a-ps ADP-ribosyltransferase 2a, pseudogene 0.101
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.101
Il4 interleukin 4 0.099
Olfr140 olfactory receptor 140 0.094
Slamf6 SLAM family member 6 0.093
Il2ra interleukin 2 receptor, alpha chain 0.092
Spp1 secreted phosphoprotein 1 0.091
S1pr4 sphingosine-1-phosphate receptor 4 0.091
Cd6 CD6 antigen 0.088
Cd4 CD4 antigen 0.086
Pdcd1lg2 programmed cell death 1 ligand 2 0.084
Pla2g2d phospholipase A2, group IID 0.082
Spn sialophorin 0.081
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.081
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.079
Foxp3 forkhead box P3 0.078
Cd19 CD19 antigen 0.077
Tnfrsf17 tumor necrosis factor receptor superfamily, member 17 0.076
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.075
Mmp8 matrix metallopeptidase 8 0.075
Cd2 CD2 antigen 0.074
Pyhin1 pyrin and HIN domain family, member 1 0.074
Elane elastase, neutrophil expressed 0.073
Il2rb interleukin 2 receptor, beta chain 0.072
Ctsw cathepsin W 0.072
Il7r interleukin 7 receptor 0.072
C5ar1 complement component 5a receptor 1 0.071
Fpr1 formyl peptide receptor 1 0.070
Retn resistin 0.070
Fgd3 FYVE, RhoGEF and PH domain containing 3 0.069
Cx3cr1 chemokine (C-X3-C) receptor 1 0.069
Igk immunoglobulin kappa chain complex 0.066
Cd160 CD160 antigen 0.066
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism