IMP
Process View
The network for 'blastocyst development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
blastocyst development
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.994 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.990 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.989 | |
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.988 | |
| Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.987 | |
| Bmp4 | bone morphogenetic protein 4 | 0.986 | |
| Sox2 | SRY-box containing gene 2 | 0.981 | |
| Nanog | Nanog homeobox | 0.979 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.978 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.971 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.961 | |
| Foxc1 | forkhead box C1 | 0.949 | |
| Pax3 | paired box gene 3 | 0.948 | |
| Shh | sonic hedgehog | 0.946 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.939 | |
| Apc | adenomatosis polyposis coli | 0.931 | |
| Smarcc1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.930 | |
| Rb1 | retinoblastoma 1 | 0.919 | |
| Trp53 | transformation related protein 53 | 0.907 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.890 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.889 | |
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.878 | |
| Sall4 | sal-like 4 (Drosophila) | 0.875 | |
| Alx4 | aristaless-like homeobox 4 | 0.851 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.850 | |
| Crebbp | CREB binding protein | 0.848 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.844 | |
| Pten | phosphatase and tensin homolog | 0.838 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.829 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.819 | |
| Nodal | nodal | 0.810 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.778 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.756 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.753 | |
| Fgf8 | fibroblast growth factor 8 | 0.742 | |
| Foxh1 | forkhead box H1 | 0.736 | |
| Msx2 | homeobox, msh-like 2 | 0.712 | |
| Msx1 | homeobox, msh-like 1 | 0.696 | |
| Pafah1b1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 | 0.673 | |
| Fos | FBJ osteosarcoma oncogene | 0.672 | |
| Cdx2 | caudal type homeobox 2 | 0.672 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.667 | |
| Alx1 | ALX homeobox 1 | 0.666 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.657 | |
| Tbx3 | T-box 3 | 0.623 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.614 | |
| Meox2 | mesenchyme homeobox 2 | 0.609 | |
| Hoxd13 | homeobox D13 | 0.596 | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.596 | |
| Dlx5 | distal-less homeobox 5 | 0.595 | |
| Sall1 | sal-like 1 (Drosophila) | 0.593 | |
| Sp1 | trans-acting transcription factor 1 | 0.593 | |
| Fgf15 | fibroblast growth factor 15 | 0.586 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.566 | |
| Psmd4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.563 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.546 | |
| Jag1 | jagged 1 | 0.542 | |
| Nf1 | neurofibromatosis 1 | 0.535 | |
| Lhx1 | LIM homeobox protein 1 | 0.522 | |
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.514 | |
| Prrx1 | paired related homeobox 1 | 0.509 | |
| Pax9 | paired box gene 9 | 0.506 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.499 | |
| Bptf | bromodomain PHD finger transcription factor | 0.498 | |
| Jun | Jun oncogene | 0.497 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.477 | |
| Foxg1 | forkhead box G1 | 0.473 | |
| Smo | smoothened homolog (Drosophila) | 0.470 | |
| Brca1 | breast cancer 1 | 0.468 | |
| Tbx15 | T-box 15 | 0.456 | |
| Sox3 | SRY-box containing gene 3 | 0.455 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.454 | |
| Egr1 | early growth response 1 | 0.449 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.433 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.418 | |
| Tcfap2c | transcription factor AP-2, gamma | 0.401 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.397 | |
| Eng | endoglin | 0.384 | |
| Gata4 | GATA binding protein 4 | 0.374 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.373 | |
| Bmp7 | bone morphogenetic protein 7 | 0.369 | |
| Hoxb13 | homeobox B13 | 0.358 | |
| Atoh1 | atonal homolog 1 (Drosophila) | 0.356 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.356 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.346 | |
| Cldn6 | claudin 6 | 0.345 | |
| Gata6 | GATA binding protein 6 | 0.340 | |
| Hdac1 | histone deacetylase 1 | 0.339 | |
| Tcf15 | transcription factor 15 | 0.336 | |
| Hmx3 | H6 homeobox 3 | 0.336 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.333 | |
| Fgf4 | fibroblast growth factor 4 | 0.330 | |
| Sox9 | SRY-box containing gene 9 | 0.328 | |
| Foxc2 | forkhead box C2 | 0.322 | |
| Hesx1 | homeobox gene expressed in ES cells | 0.322 | |
| Smad7 | MAD homolog 7 (Drosophila) | 0.320 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.316 | |
| Dll4 | delta-like 4 (Drosophila) | 0.315 | |
| Cdx1 | caudal type homeobox 1 | 0.313 | |
| Foxf1a | forkhead box F1a | 0.312 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BRCA1 | breast cancer 1, early onset | 0.986 | |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.981 | |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.976 | |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.976 | |
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.964 | |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.961 | |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.957 | |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.945 | |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.938 | |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.930 | |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.918 | |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.918 | |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.902 | |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.881 | |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.857 | |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.850 | |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.841 | |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.825 | |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.821 | |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.810 | |
| H2AFX | H2A histone family, member X | 0.807 | |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.801 | |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.780 | |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.780 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.775 | |
| SP1 | Sp1 transcription factor | 0.773 | |
| POU5F1 | POU class 5 homeobox 1 | 0.765 | |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.764 | |
| EP300 | E1A binding protein p300 | 0.757 | |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.735 | |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.725 | |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.713 | |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.699 | |
| SMC2 | structural maintenance of chromosomes 2 | 0.691 | |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.676 | |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.674 | |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.673 | |
| FANCD2 | Fanconi anemia, complementation group D2 | 0.661 | |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.656 | |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.627 | |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.614 | |
| CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.591 | |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.582 | |
| SMAD2 | SMAD family member 2 | 0.555 | |
| BARD1 | BRCA1 associated RING domain 1 | 0.555 | |
| AATF | apoptosis antagonizing transcription factor | 0.552 | |
| FOXD3 | forkhead box D3 | 0.551 | |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.548 | |
| LEO1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.538 | |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.491 | |
| MSH6 | mutS homolog 6 (E. coli) | 0.449 | |
| SMAD4 | SMAD family member 4 | 0.436 | |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.423 | |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.421 | |
| POMP | proteasome maturation protein | 0.387 | |
| MKL1 | megakaryoblastic leukemia (translocation) 1 | 0.386 | |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.362 | |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.351 | |
| EHF | ets homologous factor | 0.342 | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.327 | |
| SMC4 | structural maintenance of chromosomes 4 | 0.323 | |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.321 | |
| SMAD3 | SMAD family member 3 | 0.320 | |
| CAPNS1 | calpain, small subunit 1 | 0.319 | |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.306 | |
| TGFB1 | transforming growth factor, beta 1 | 0.294 | |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.280 | |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.273 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.270 | |
| PDX1 | pancreatic and duodenal homeobox 1 | 0.257 | |
| FBXO5 | F-box protein 5 | 0.255 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.244 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.234 | |
| CDK4 | cyclin-dependent kinase 4 | 0.231 | |
| MYOD1 | myogenic differentiation 1 | 0.225 | |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.219 | |
| JMJD6 | jumonji domain containing 6 | 0.219 | |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.219 | |
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.213 | |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 0.212 | |
| CCNT1 | cyclin T1 | 0.209 | |
| CREBBP | CREB binding protein | 0.200 | |
| NCAPH2 | non-SMC condensin II complex, subunit H2 | 0.198 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.197 | |
| MYOCD | myocardin | 0.191 | |
| GATA2 | GATA binding protein 2 | 0.190 | |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.186 | |
| RAD51AP1 | RAD51 associated protein 1 | 0.185 | |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.184 | |
| MYOG | myogenin (myogenic factor 4) | 0.182 | |
| MESDC2 | mesoderm development candidate 2 | 0.177 | |
| MED6 | mediator complex subunit 6 | 0.172 | |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.160 | |
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.156 | |
| MED10 | mediator complex subunit 10 | 0.155 | |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.153 | |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 0.150 | |
| JUN | jun proto-oncogene | 0.149 | |
| RRM1 | ribonucleotide reductase M1 | 0.145 | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.143 |