The network for 'transmembrane receptor protein serine threonine kinase signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

transmembrane receptor protein serine threonine kinase signaling pathway

A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.

Mus musculus
Name Description Probability Func Analog Organism
Bmp4 bone morphogenetic protein 4 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Smo smoothened homolog (Drosophila) 0.998
Shh sonic hedgehog 0.997
Smad6 MAD homolog 6 (Drosophila) 0.996
Tgfb2 transforming growth factor, beta 2 0.996
Gli3 GLI-Kruppel family member GLI3 0.996
Chrd chordin 0.995
Tgfbr2 transforming growth factor, beta receptor II 0.995
Fgfr2 fibroblast growth factor receptor 2 0.992
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.992
Bmp7 bone morphogenetic protein 7 0.992
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.991
Axin1 axin 1 0.987
Smad7 MAD homolog 7 (Drosophila) 0.984
Nodal nodal 0.984
Zic3 zinc finger protein of the cerebellum 3 0.982
Pten phosphatase and tensin homolog 0.976
Pax3 paired box gene 3 0.972
Foxc2 forkhead box C2 0.969
Smad3 MAD homolog 3 (Drosophila) 0.969
Onecut1 one cut domain, family member 1 0.966
Rarb retinoic acid receptor, beta 0.965
Fgfr1 fibroblast growth factor receptor 1 0.960
Tbx1 T-box 1 0.953
En1 engrailed 1 0.951
Fgf8 fibroblast growth factor 8 0.949
Apc adenomatosis polyposis coli 0.949
Hes1 hairy and enhancer of split 1 (Drosophila) 0.948
Smad4 MAD homolog 4 (Drosophila) 0.946
Jag1 jagged 1 0.945
Otx2 orthodenticle homolog 2 (Drosophila) 0.940
Hand1 heart and neural crest derivatives expressed transcript 1 0.939
Foxf1a forkhead box F1a 0.936
Vegfa vascular endothelial growth factor A 0.932
Gli2 GLI-Kruppel family member GLI2 0.932
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.931
Pitx2 paired-like homeodomain transcription factor 2 0.931
Efnb2 ephrin B2 0.926
Msx2 homeobox, msh-like 2 0.919
Mstn myostatin 0.913
Nog noggin 0.912
Gata4 GATA binding protein 4 0.912
Prrx1 paired related homeobox 1 0.908
Foxh1 forkhead box H1 0.907
Twist1 twist homolog 1 (Drosophila) 0.906
Gata6 GATA binding protein 6 0.903
Barx1 BarH-like homeobox 1 0.902
Bgn biglycan 0.900
Wnt5a wingless-related MMTV integration site 5A 0.900
Lox lysyl oxidase 0.897
Tbx3 T-box 3 0.897
Fst follistatin 0.897
Lmx1a LIM homeobox transcription factor 1 alpha 0.884
Hic1 hypermethylated in cancer 1 0.882
Sfrp2 secreted frizzled-related protein 2 0.879
Hoxa13 homeobox A13 0.870
Hoxa1 homeobox A1 0.861
Ptk2 PTK2 protein tyrosine kinase 2 0.858
Rb1 retinoblastoma 1 0.853
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.847
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.846
Acvr2b activin receptor IIB 0.841
Alx4 aristaless-like homeobox 4 0.840
Tbx2 T-box 2 0.827
Trp63 transformation related protein 63 0.826
Bmp2 bone morphogenetic protein 2 0.826
Atoh7 atonal homolog 7 (Drosophila) 0.821
Gdnf glial cell line derived neurotrophic factor 0.809
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.809
Wnt3a wingless-related MMTV integration site 3A 0.809
Tgfbr1 transforming growth factor, beta receptor I 0.804
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.801
Gas1 growth arrest specific 1 0.798
Tlx3 T-cell leukemia, homeobox 3 0.796
Twist2 twist homolog 2 (Drosophila) 0.796
Pou3f3 POU domain, class 3, transcription factor 3 0.792
Alx3 aristaless-like homeobox 3 0.782
Msh2 mutS homolog 2 (E. coli) 0.781
Foxc1 forkhead box C1 0.776
Hoxd13 homeobox D13 0.774
Meox2 mesenchyme homeobox 2 0.772
Atf2 activating transcription factor 2 0.771
Bdnf brain derived neurotrophic factor 0.759
Acvr1 activin A receptor, type 1 0.756
Gsc goosecoid homeobox 0.740
Ntf3 neurotrophin 3 0.738
Axin2 axin2 0.736
Wnt1 wingless-related MMTV integration site 1 0.733
Id3 inhibitor of DNA binding 3 0.731
Lef1 lymphoid enhancer binding factor 1 0.727
Egr1 early growth response 1 0.724
Fzd8 frizzled homolog 8 (Drosophila) 0.717
Amhr2 anti-Mullerian hormone type 2 receptor 0.710
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.709
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.709
Pkd2 polycystic kidney disease 2 0.705
Hand2 heart and neural crest derivatives expressed transcript 2 0.702
Eln elastin 0.700
Snai1 snail homolog 1 (Drosophila) 0.699
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
daf-11 Protein DAF-11 0.859
egl-18 Protein EGL-18 0.776
daf-4 Protein DAF-4 0.324
daf-1 Protein DAF-1 0.283
pkg-1 Protein PKG-1 0.269
unc-73 Protein UNC-73 0.183
gcy-22 Protein GCY-22 0.108
egl-15 Protein EGL-15 0.102
R05G6.10 Protein R05G6.10 0.100
eya-1 Protein EYA-1 0.091
daf-3 Protein DAF-3 0.091
odr-3 Protein ODR-3 0.085
lin-17 Protein LIN-17 0.076
daf-12 Protein DAF-12 0.075
nhr-45 Protein NHR-45 0.074
mab-31 Protein MAB-31 0.071
osm-3 Protein OSM-3 0.068
npp-22 Protein NPP-22 0.066
nhr-67 Protein NHR-67 0.062
vab-3 Protein VAB-3 0.061
cat-1 Protein CAT-1 0.061
nhr-25 Protein NHR-25 0.061
pry-1 Protein PRY-1 0.061
mab-5 Protein MAB-5 0.060
pqn-62 Protein PQN-62 0.060
ceh-20 Protein CEH-20 0.059
dlk-1 Protein DLK-1 0.053
pmp-3 Protein PMP-3 0.052
ncam-1 Protein NCAM-1 0.051
F18H3.4 Protein F18H3.4 0.050
daf-14 Protein DAF-14 0.049
unc-83 Protein UNC-83 0.049
lin-29 Protein LIN-29 0.047
hlh-2 Protein HLH-2 0.046
imp-3 Protein IMP-3 0.046
sym-1 Protein SYM-1 0.045
nipi-3 Protein NIPI-3 0.045
che-13 Protein CHE-13 0.044
olrn-1 Protein OLRN-1 0.044
lag-2 Protein LAG-2 0.043
tag-320 Protein TAG-320 0.041
daf-2 Protein DAF-2 0.041
hlh-30 Protein HLH-30 0.040
abl-1 Protein ABL-1 0.040
cyd-1 Protein CYD-1 0.039
acy-1 Protein ACY-1 0.037
egl-8 Protein EGL-8 0.037
lin-25 Protein LIN-25 0.036
sel-12 Protein SEL-12 0.034
vab-8 Protein VAB-8 0.034
sma-10 Protein SMA-10 0.033
nhr-46 Protein NHR-46 0.032
gei-8 Protein GEI-8 0.030
T28F4.1 Protein T28F4.1 0.028
uggt-1 Protein UGGT-1 0.028
tax-4 Protein TAX-4 0.027
CELE_C01G6.5 Protein C01G6.5 0.027
inx-3 Protein INX-3 0.026
let-60 Protein LET-60 0.026
mom-2 Protein MOM-2 0.026
lpin-1 Protein LPIN-1 0.025
ceh-16 Protein CEH-16 0.025
eor-2 Protein EOR-2 0.025
tag-196 Protein TAG-196 0.025
lin-66 Protein LIN-66 0.025
egl-44 Protein EGL-44 0.024
csn-1 Protein CSN-1 0.024
CELE_F56D5.6 Protein F56D5.6 0.024
lin-3 Protein LIN-3 0.023
cdf-1 Protein CDF-1 0.023
teg-4 Protein TEG-4 0.023
C16C8.2 Protein C16C8.2 0.023
ztf-2 Protein ZTF-2 0.022
che-1 Protein CHE-1 0.022
sea-2 Protein SEA-2 0.022
lin-36 Protein LIN-36 0.022
apm-3 Protein APM-3 0.022
ceh-32 Protein CEH-32 0.022
osm-5 Protein OSM-5 0.022
unc-7 Protein UNC-7 0.021
peb-1 Protein PEB-1 0.021
pop-1 Protein POP-1 0.020
CELE_C33D9.6 Protein C33D9.6 0.020
sel-8 Protein SEL-8 0.020
F42C5.9 Protein F42C5.9 0.020
aha-1 Protein AHA-1 0.020
rgs-7 Protein RGS-7 0.020
Y40C5A.1 Protein Y40C5A.1 0.019
gopc-1 Protein GOPC-1 0.019
eps-8 Protein EPS-8 0.019
T23F4.2 Protein T23F4.2 0.019
rad-54 Protein RAD-54 0.019
lin-59 Protein LIN-59 0.019
R10E4.1 Protein R10E4.1 0.018
pmk-1 Protein PMK-1 0.018
T28F4.4 Protein T28F4.4 0.018
cam-1 Protein CAM-1 0.018
nhr-34 Protein NHR-34 0.018
flh-1 Protein FLH-1 0.018
che-3 Protein CHE-3 0.017
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.999
shha sonic hedgehog a 0.988
gli2a GLI-Kruppel family member GLI2a 0.978
bmp2b bone morphogenetic protein 2b 0.942
smo smoothened homolog (Drosophila) 0.920
notch1a notch homolog 1a 0.908
crabp2a cellular retinoic acid binding protein 2, a 0.889
fgf8a fibroblast growth factor 8 a 0.861
ndr2 nodal-related 2 0.856
sox9a SRY-box containing gene 9a 0.827
twist3 twist3 0.802
flh floating head 0.788
gli1 GLI-Kruppel family member 1 0.780
lmo4a LIM domain only 4a 0.769
bmp4 bone morphogenetic protein 4 0.754
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.741
tbx2b T-box 2b 0.710
fn1 fibronectin 1 0.698
tbx1 T-box 1 0.685
tbx16 T-box gene 16 0.652
dcc deleted in colorectal carcinoma 0.649
dusp6 dual specificity phosphatase 6 0.640
hand2 heart and neural crest derivatives expressed transcript 2 0.635
ctsl1b cathepsin L, 1 b 0.634
rarab retinoic acid receptor, alpha b 0.577
lhx2b LIM homeobox 2b 0.560
zic5 zic family member 5 (odd-paired homolog, Drosophila) 0.548
gbx2 gastrulation brain homeo box 2 0.547
col2a1a collagen type II, alpha-1a 0.527
fgfr1b fibroblast growth factor receptor 1b 0.527
egr1 early growth response 1 0.507
oep one-eyed pinhead 0.491
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.489
foxa3 forkhead box A3 0.447
gdf9 growth differentiation factor 9 0.439
nkx2.5 NK2 transcription factor related 5 0.438
dlx2a distal-less homeobox gene 2a 0.426
her6 hairy-related 6 0.425
hs6st2 heparan sulfate 6-O-sulfotransferase 2 0.417
ptch1 patched 1 0.404
rasl11b RAS-like, family 11, member B 0.392
hs6st1a heparan sulfate 6-O-sulfotransferase 1a 0.391
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.371
six3a sine oculis homeobox homolog 3a 0.368
ptch2 patched 2 0.365
sox9b SRY-box containing gene 9b 0.363
bmp2a bone morphogenetic protein 2a 0.360
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.356
wnt11r wingless-type MMTV integration site family, member 11, related 0.346
wnt5b wingless-type MMTV integration site family, member 5b 0.341
pcdh18a protocadherin 18a 0.340
col1a1a collagen, type I, alpha 1a 0.336
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.335
raraa retinoic acid receptor, alpha a 0.333
nkd1 naked cuticle homolog 1 (Drosophila) 0.330
wnt8a wingless-type MMTV integration site family, member 8a 0.322
fzd7b frizzled homolog 7b 0.307
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.293
fgf10a fibroblast growth factor 10a 0.291
runx2b runt-related transcription factor 2b 0.288
tfap2a transcription factor AP-2 alpha 0.280
cxcr4a chemokine (C-X-C motif) receptor 4a 0.277
cdx1b caudal type homeobox 1 b 0.276
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.270
nkd2 naked cuticle homolog 2 and naked 2a 0.270
hdac4 histone deacetylase 4 0.269
sdc2 syndecan 2 0.265
lmna lamin A 0.258
pax9 paired box gene 9 0.256
sulf1 sulfatase 1 0.255
th tyrosine hydroxylase 0.254
tbx18 T-box 18 0.251
spry4 sprouty (Drosophila) homolog 4 0.248
acvr2b activin receptor IIb 0.246
eng2b engrailed 2b 0.245
fzd8b frizzled homolog 8b 0.241
nanos3 nanos homolog 3 0.239
hoxa13b homeo box A13b 0.236
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.234
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.231
pitx3 paired-like homeodomain transcription factor 3 0.227
gpc4 glypican 4 0.227
pcdh19 protocadherin 19 0.226
tll1 tolloid-like 1 0.226
aplnra apelin receptor a 0.222
edn1 endothelin 1 0.217
cdh5 cadherin 5 0.214
s1pr2 sphingosine-1-phosphate receptor 2 0.211
etv5b ets variant 5b 0.209
foxo3b forkhead box O3b 0.204
ntla no tail a 0.203
sox11a SRY-box containing gene 11a 0.199
col27a1a collagen, type XXVII, alpha 1a 0.199
smad1 MAD homolog 1 (Drosophila) 0.190
gsc goosecoid 0.187
junb jun B proto-oncogene 0.186
mapk1 mitogen-activated protein kinase 1 0.183
rgma RGM domain family, member A 0.183
drl draculin 0.181
igf2a insulin-like growth factor 2a 0.180
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
tkv thickveins 0.998
kay kayak 0.997
Egfr Epidermal growth factor receptor 0.989
Dad Daughters against dpp 0.977
ci cubitus interruptus 0.950
dpp decapentaplegic 0.933
sog short gastrulation 0.905
brk brinker 0.888
gbb glass bottom boat 0.865
babo baboon 0.852
wit wishful thinking 0.845
tld tolloid 0.818
ush u-shaped 0.794
mbc myoblast city 0.776
ttv tout-velu 0.755
shn schnurri 0.750
stck steamer duck 0.689
Mer Merlin 0.656
yki yorkie 0.646
tok tolkin 0.590
Pk61C Protein kinase 61C 0.566
EcR Ecdysone receptor 0.565
HLHm7 E(spl) region transcript m7 0.564
Lam Lamin 0.534
pyd polychaetoid 0.528
mys myospheroid 0.498
dally division abnormally delayed 0.495
Nup98 Nucleoporin 98 0.477
E(spl) Enhancer of split 0.476
emc extra macrochaetae 0.467
kn knot 0.458
aux auxillin 0.457
unc-104 CG8566 gene product from transcript CG8566-RB 0.444
dm diminutive 0.439
puc puckered 0.436
G-oalpha47A G protein oalpha 47A 0.434
wun wunen 0.428
ab abrupt 0.411
Smox Smad on X 0.389
Socs36E Suppressor of cytokine signaling at 36E 0.382
spen split ends 0.380
Tl Toll 0.375
Atg1 Autophagy-specific gene 1 0.374
hpo hippo 0.368
sbb scribbler 0.367
Mad Mothers against dpp 0.360
chico CG5686 gene product from transcript CG5686-RB 0.351
HLHm5 E(spl) region transcript m5 0.350
if inflated 0.342
gro groucho 0.338
rl rolled 0.334
Sdc Syndecan 0.329
Irk2 Inwardly rectifying potassium channel 2 0.322
Stat92E Signal-transducer and activator of transcription protein at 92E 0.321
HLHm3 E(spl) region transcript m3 0.307
cv-2 crossveinless 2 0.306
Ext2 CG8433 gene product from transcript CG8433-RA 0.297
wts warts 0.297
spi spitz 0.297
Nup214 Nucleoporin 214 0.276
HLHmbeta E(spl) region transcript mbeta 0.269
argos CG4531 gene product from transcript CG4531-RA 0.258
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.254
Myo31DF Myosin 31DF 0.253
zfh1 Zn finger homeodomain 1 0.249
Sulf1 Sulfated 0.245
scb scab 0.243
N Notch 0.243
HLHmgamma E(spl) region transcript mgamma 0.240
Dl Delta 0.233
fkh fork head 0.230
cwo clockwork orange 0.224
hep hemipterous 0.224
sfl sulfateless 0.220
rho rhomboid 0.219
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.218
nkd naked cuticle 0.216
en engrailed 0.211
par-1 CG8201 gene product from transcript CG8201-RA 0.209
SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit 0.207
coro CG9446 gene product from transcript CG9446-RC 0.202
sd scalloped 0.200
rhea CG6831 gene product from transcript CG6831-RA 0.199
hh hedgehog 0.196
ena enabled 0.188
l(2)gl lethal (2) giant larvae 0.181
pan pangolin 0.181
Fak56D Focal Adhesion Kinase 0.180
HLHmdelta E(spl) region transcript mdelta 0.179
Mef2 Myocyte enhancer factor 2 0.177
tws twins 0.176
Pak PAK-kinase 0.171
bam bag of marbles 0.170
Su(H) Suppressor of Hairless 0.170
ft fat 0.168
sax saxophone 0.165
Rel Relish 0.162
tou toutatis 0.160
loco locomotion defects 0.159
CG16884 CG16884 gene product from transcript CG16884-RA 0.156
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SMAD4 SMAD family member 4 1.000
SMAD3 SMAD family member 3 1.000
SMAD2 SMAD family member 2 1.000
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
JUN jun proto-oncogene 1.000
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.000
SMAD7 SMAD family member 7 1.000
TP53 tumor protein p53 1.000
FN1 fibronectin 1 1.000
FHL2 four and a half LIM domains 2 1.000
SKIL SKI-like oncogene 0.999
FOS FBJ murine osteosarcoma viral oncogene homolog 0.999
JUNB jun B proto-oncogene 0.998
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.996
FYN FYN oncogene related to SRC, FGR, YES 0.992
COL1A1 collagen, type I, alpha 1 0.987
FBLN1 fibulin 1 0.985
TGFB1 transforming growth factor, beta 1 0.982
PTK2 PTK2 protein tyrosine kinase 2 0.979
CREBBP CREB binding protein 0.978
FLNA filamin A, alpha 0.977
ATF3 activating transcription factor 3 0.977
SMAD5 SMAD family member 5 0.971
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.969
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.962
SMAD1 SMAD family member 1 0.961
PXN paxillin 0.954
TGFBR1 transforming growth factor, beta receptor 1 0.950
KPNB1 karyopherin (importin) beta 1 0.947
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.943
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.943
AR androgen receptor 0.934
EP300 E1A binding protein p300 0.915
MAPK8 mitogen-activated protein kinase 8 0.910
CAV1 caveolin 1, caveolae protein, 22kDa 0.897
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.892
DUSP1 dual specificity phosphatase 1 0.879
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.867
SKI v-ski sarcoma viral oncogene homolog (avian) 0.864
BMP2 bone morphogenetic protein 2 0.862
MAPK1 mitogen-activated protein kinase 1 0.857
NRP1 neuropilin 1 0.842
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.839
SMAD6 SMAD family member 6 0.837
SIRT1 sirtuin 1 0.837
JAG1 jagged 1 0.804
ZFYVE9 zinc finger, FYVE domain containing 9 0.800
CTBP1 C-terminal binding protein 1 0.793
SP1 Sp1 transcription factor 0.793
ACVR1B activin A receptor, type IB 0.776
MAP2K4 mitogen-activated protein kinase kinase 4 0.773
CTGF connective tissue growth factor 0.769
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.768
ADRB1 adrenergic, beta-1-, receptor 0.759
ENG endoglin 0.739
SYK spleen tyrosine kinase 0.730
BCAR1 breast cancer anti-estrogen resistance 1 0.728
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.710
BMPR1A bone morphogenetic protein receptor, type IA 0.697
FLNB filamin B, beta 0.695
LCK lymphocyte-specific protein tyrosine kinase 0.695
ABI2 abl-interactor 2 0.695
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.694
ATF2 activating transcription factor 2 0.680
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.675
SNX9 sorting nexin 9 0.661
HIPK3 homeodomain interacting protein kinase 3 0.658
LIN7B lin-7 homolog B (C. elegans) 0.651
ERBB2IP erbb2 interacting protein 0.651
AHCTF1 AT hook containing transcription factor 1 0.651
COL5A2 collagen, type V, alpha 2 0.640
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.632
ESR1 estrogen receptor 1 0.630
BMP1 bone morphogenetic protein 1 0.617
TGFB3 transforming growth factor, beta 3 0.616
MXRA5 matrix-remodelling associated 5 0.612
PAX3 paired box 3 0.601
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.586
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.578
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.578
TRIM33 tripartite motif containing 33 0.577
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.573
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.565
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.554
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.544
TBX5 T-box 5 0.521
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.520
IER2 immediate early response 2 0.516
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.511
SNX33 sorting nexin 33 0.509
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.507
FOXD3 forkhead box D3 0.497
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.478
CYR61 cysteine-rich, angiogenic inducer, 61 0.478
VCL vinculin 0.472
SNAI1 snail homolog 1 (Drosophila) 0.469
IGFBP3 insulin-like growth factor binding protein 3 0.466
PTEN phosphatase and tensin homolog 0.464
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.460
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Col1a1 collagen, type I, alpha 1 0.720
Fos FBJ osteosarcoma oncogene 0.684
Btg2 BTG family, member 2 0.616
Junb jun B proto-oncogene 0.603
Egr1 early growth response 1 0.479
Dusp1 dual specificity phosphatase 1 0.475
Smad7 SMAD family member 7 0.425
Pmepa1 prostate transmembrane protein, androgen induced 1 0.318
Klf4 Kruppel-like factor 4 (gut) 0.277
Anxa5 annexin A5 0.254
Pdia6 protein disulfide isomerase family A, member 6 0.201
Ncan neurocan 0.188
Itgb1 integrin, beta 1 0.177
Id3 inhibitor of DNA binding 3 0.173
Adra2b adrenergic, alpha-2B-, receptor 0.171
Ece1 endothelin converting enzyme 1 0.165
Lox lysyl oxidase 0.143
Hes1 hairy and enhancer of split 1 (Drosophila) 0.141
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.141
Fbln5 fibulin 5 0.141
Col4a4 collagen, type IV, alpha 4 0.139
Hsp90b1 heat shock protein 90, beta, member 1 0.138
Ier2 immediate early response 2 0.130
Flt1 FMS-related tyrosine kinase 1 0.130
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.128
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.125
Tgfb1 transforming growth factor, beta 1 0.115
Postn periostin, osteoblast specific factor 0.114
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.105
Gja3 gap junction protein, alpha 3 0.100
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.098
Syt8 synaptotagmin VIII 0.096
Loxl1 lysyl oxidase-like 1 0.095
Klf6 Kruppel-like factor 6 0.093
Dusp6 dual specificity phosphatase 6 0.090
Rest RE1-silencing transcription factor 0.090
Fn1 fibronectin 1 0.086
Ednra endothelin receptor type A 0.085
Jak2 Janus kinase 2 0.084
Lama5 laminin, alpha 5 0.082
Sox17 SRY (sex determining region Y)-box 17 0.081
Dmd dystrophin 0.079
Col5a2 collagen, type V, alpha 2 0.077
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.071
Cdc42 cell division cycle 42 (GTP binding protein) 0.071
Cish cytokine inducible SH2-containing protein 0.069
Fstl1 follistatin-like 1 0.068
Met met proto-oncogene 0.065
Bgn biglycan 0.060
Adrb1 adrenergic, beta-1-, receptor 0.059
Klf2 Kruppel-like factor 2 (lung) 0.059
Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.058
Tgfb3 transforming growth factor, beta 3 0.058
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.058
Gata4 GATA binding protein 4 0.056
Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.056
Ssbp4 single stranded DNA binding protein 4 0.056
Grm5 glutamate receptor, metabotropic 5 0.056
Lamc1 laminin, gamma 1 0.055
Tgfbr2 transforming growth factor, beta receptor II 0.055
Ahr aryl hydrocarbon receptor 0.054
Agtr1a angiotensin II receptor, type 1a 0.053
Mafb v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 0.049
Col4a1 collagen, type IV, alpha 1 0.049
Slit3 slit homolog 3 (Drosophila) 0.049
Tagln transgelin 0.049
Dlgap2 discs, large (Drosophila) homolog-associated protein 2 0.049
Arnt aryl hydrocarbon receptor nuclear translocator 0.046
Egr2 early growth response 2 0.045
Cd97 CD97 molecule 0.045
Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.044
RGD1311493 similar to CG13379-PA 0.043
Prkch protein kinase C, eta 0.043
Pde4a phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) 0.043
Ube3a ubiquitin protein ligase E3A 0.043
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.041
Igf2r insulin-like growth factor 2 receptor 0.040
Ntn1 netrin 1 0.039
Smad3 SMAD family member 3 0.039
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.039
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.038
Cpsf2 cleavage and polyadenylation specific factor 2 0.038
Slc4a2 solute carrier family 4 (anion exchanger), member 2 0.038
Fam198b family with sequence similarity 198, member B 0.037
Ghrl ghrelin/obestatin prepropeptide 0.037
Mcam melanoma cell adhesion molecule 0.037
Creb1 cAMP responsive element binding protein 1 0.037
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.036
Myl9 myosin, light chain 9, regulatory 0.036
Rara retinoic acid receptor, alpha 0.036
LOC313672 kazrin 0.036
Vdac1 voltage-dependent anion channel 1 0.035
Hand2 heart and neural crest derivatives expressed 2 0.035
Kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.035
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.035
Klhl31 kelch-like 31 (Drosophila) 0.035
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.034
Stat6 signal transducer and activator of transcription 6 0.034
Irf2 interferon regulatory factor 2 0.034
Acta2 smooth muscle alpha-actin 0.034
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism