IMP

Process View

Drosophila melanogaster

22 genes annotated in fly

actin cytoskeleton reorganization

A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "actin cytoskeleton reorganization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "actin cytoskeleton reorganization" (in gray)

Name	Description	Probability	Func Analog Organism
Cdc42	CG12530 gene product from transcript CG12530-RA	0.969
msn	misshapen	0.960	Human
mbc	myoblast city	0.843
sqh	spaghetti squash	0.778
Rac1	CG2248 gene product from transcript CG2248-RA	0.618
kst	karst	0.608
chic	chickadee	0.588
Akt1	CG4006 gene product from transcript CG4006-RA	0.579
egh	egghead	0.558
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.539
dock	dreadlocks	0.471
flw	flapwing	0.437
JIL-1	CG6297 gene product from transcript CG6297-RA	0.393
trio	CG18214 gene product from transcript CG18214-RA	0.389
Rab5	Rab-protein 5	0.371
baz	bazooka	0.304
Lis-1	Lissencephaly-1	0.299
Arp66B	Actin-related protein 66B	0.294
Rho1	CG8416 gene product from transcript CG8416-RB	0.272
Ptp69D	Protein tyrosine phosphatase 69D	0.256
mys	myospheroid	0.228
drk	downstream of receptor kinase	0.225
Wnk	CG7177 gene product from transcript CG7177-RA	0.194
Sra-1	specifically Rac1-associated protein 1	0.185
Rala	Ras-related protein	0.185	Human
Chc	Clathrin heavy chain	0.181
ttk	tramtrack	0.173
how	held out wings	0.167
Smox	Smad on X	0.163
bif	bifocal	0.156
Act5C	Actin 5C	0.153
zip	zipper	0.147	Human
Abi	Abelson interacting protein	0.137
ena	enabled	0.135
BicD	Bicaudal D	0.126
Rab7	Rab-protein 7	0.126
par-1	CG8201 gene product from transcript CG8201-RA	0.126
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.126
cher	cheerio	0.116	Human
babo	baboon	0.111
retn	retained	0.102
Hem	HEM-protein	0.096
Dhc64C	Dynein heavy chain 64C	0.094
fra	frazzled	0.092
NetB	Netrin-B	0.086
Pk61C	Protein kinase 61C	0.086
trc	tricornered	0.083
Vrp1	Verprolin 1	0.080
plexB	plexin B	0.078
jim	CG11352 gene product from transcript CG11352-RB	0.076
Nrx-IV	Neurexin IV	0.075
Gug	Grunge	0.074
pod1	CG4532 gene product from transcript CG4532-RF	0.074
RhoL	rho-like	0.072	Fly
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.072
cpb	capping protein beta	0.071
htl	heartless	0.071
Pvr	PDGF- and VEGF-receptor related	0.070	Human Mouse
myoglianin	CG1838 gene product from transcript CG1838-RD	0.070
G-oalpha47A	G protein oalpha 47A	0.065
kel	kelch	0.065
shot	short stop	0.065
Pkn	Protein kinase related to protein kinase N	0.064
cdi	center divider	0.062
pcx	pecanex	0.062
hts	hu li tai shao	0.061	Worm
l(2)gl	lethal (2) giant larvae	0.056
jagn	jagunal	0.056
bchs	blue cheese	0.055
ck	crinkled	0.052
egl	egalitarian	0.052
rhea	CG6831 gene product from transcript CG6831-RA	0.051
gek	genghis khan	0.051	Human Rat Fly
Rab6	Rab-protein 6	0.043
Src64B	Src oncogene at 64B	0.043	Human
Tm2	Tropomyosin 2	0.043
Rab2	Rab-protein 2	0.042
p130CAS	CG1212 gene product from transcript CG1212-RA	0.042
Dp1	Dodeca-satellite-binding protein 1	0.039
EndoGI	Endonuclease G inhibitor	0.039
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.039
Sbf	SET domain binding factor	0.038
LanA	Laminin A	0.037
Khc	Kinesin heavy chain	0.036
Dlic	Dynein light intermediate chain	0.036
Ras64B	Ras oncogene at 64B	0.036
pbl	pebble	0.035
wun	wunen	0.035
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.035
scb	scab	0.035
Gprk2	G protein-coupled receptor kinase 2	0.035
aop	anterior open	0.035
sls	sallimus	0.034
Imp	IGF-II mRNA-binding protein	0.034
hipk	homeodomain interacting protein kinase	0.034
cindr	CIN85 and CD2AP orthologue	0.033	Mouse
l(2)k16918	lethal (2) k16918	0.033
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.033
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.032
Su(dx)	Suppressor of deltex	0.032
Cortactin	CG3637 gene product from transcript CG3637-RA	0.031
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.031
klar	klarsicht	0.030
CalpB	Calpain-B	0.030
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.030
Mtl	Mig-2-like	0.029
CG10413	CG10413 gene product from transcript CG10413-RA	0.029
Pak	PAK-kinase	0.028	Human
Pax	Paxillin	0.028
rok	Rho-kinase	0.028
Mkk4	MAP kinase kinase 4	0.027
repo	reversed polarity	0.027
Vps35	Vacuolar protein sorting 35	0.026
S6k	RPS6-p70-protein kinase	0.026
tai	taiman	0.026
drpr	draper	0.026	Worm
kug	kugelei	0.025
pll	pelle	0.025
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.025
CG15099	CG15099 gene product from transcript CG15099-RA	0.024
HSPC300	CG30173 gene product from transcript CG30173-RA	0.024
DAAM	Dishevelled Associated Activator of Morphogenesis	0.023
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.023
Eph	Eph receptor tyrosine kinase	0.023
coro	CG9446 gene product from transcript CG9446-RC	0.022	Fly
lola	longitudinals lacking	0.022
Fim	Fimbrin	0.021
plexA	plexin A	0.021
zfh1	Zn finger homeodomain 1	0.021
vimar	visceral mesodermal armadillo-repeats	0.021
oys	oysgedart	0.020
otk	off-track	0.020	Human
Cip4	CG15015 gene product from transcript CG15015-RA	0.020
cpa	capping protein alpha	0.019
fwd	four wheel drive	0.019
Sema-1b	CG6446 gene product from transcript CG6446-RA	0.019
CG11210	CG11210 gene product from transcript CG11210-RA	0.018
Unc-76	CG3981 gene product from transcript CG3981-RB	0.018
Mmp1	Matrix metalloproteinase 1	0.018
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.017
dia	diaphanous	0.017
Zasp66	Z band alternatively spliced PDZ-motif protein 66	0.017
Hip14	Huntingtin-interacting protein 14	0.017
CG8578	CG8578 gene product from transcript CG8578-RA	0.016
Arf79F	ADP ribosylation factor 79F	0.016
beat-Ic	beaten path Ic	0.016
Sdc	Syndecan	0.016
CBP	sarcoplasmic calcium-binding protein	0.016
Arf51F	ADP ribosylation factor 51F	0.016
grk	gurken	0.016
lqf	liquid facets	0.015
katanin-60	katanin 60	0.015
stai	stathmin	0.015
Cad87A	CG6977 gene product from transcript CG6977-RA	0.015
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.015
CG31352	CG31352 gene product from transcript CG31352-RA	0.015
nvy	nervy	0.015
CG11486	CG11486 gene product from transcript CG11486-RG	0.015
shrb	shrub	0.015
CG2747	CG2747 gene product from transcript CG2747-RD	0.014
betaInt-nu	beta[nu] integrin	0.014
Nrg	Neuroglian	0.014
wdb	widerborst	0.013
Apc	APC-like	0.013
Gef26	CG9491 gene product from transcript CG9491-RB	0.013
pgant5	polypeptide GalNAc transferase 5	0.013
Ten-m	Tenascin major	0.013
crq	croquemort	0.013
NFAT	NFAT homolog	0.013
l(1)G0232	lethal (1) G0232	0.012
dally	division abnormally delayed	0.012
ogre	optic ganglion reduced	0.012
CG6509	CG6509 gene product from transcript CG6509-RB	0.012
Smg5	CG8954 gene product from transcript CG8954-RA	0.012
spen	split ends	0.012
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.012
Rab14	Rab-protein 14	0.012
Sur-8	CG5407 gene product from transcript CG5407-RA	0.012
Lasp	CG3849 gene product from transcript CG3849-RB	0.012
RhoGAP100F	CG1976 gene product from transcript CG1976-RB	0.012
arm	armadillo	0.012
Mef2	Myocyte enhancer factor 2	0.012
CG9801	CG9801 gene product from transcript CG9801-RC	0.011
schlank	CG3576 gene product from transcript CG3576-RB	0.011
Flo-2	flotillin 2	0.011
Atx2	Ataxin-2	0.011
Mob2	CG11711 gene product from transcript CG11711-RC	0.011
Dsk	Drosulfakinin	0.011
tmod	tropomodulin	0.011
nudE	CG8104 gene product from transcript CG8104-RB	0.011
CG10011	CG10011 gene product from transcript CG10011-RA	0.011
cbt	cabut	0.011
cno	canoe	0.011
shn	schnurri	0.011
l(2)08717	lethal (2) 08717	0.011
kon	kon-tiki	0.011
toc	toucan	0.011
tok	tolkin	0.011
Ptp99A	Protein tyrosine phosphatase 99A	0.011
Rab8	Rab-protein 8	0.011
Ced-12	CG5336 gene product from transcript CG5336-RA	0.011	Worm
LanB2	Laminin B2	0.011
chb	chromosome bows	0.011
scyl	scylla	0.011
Rel	Relish	0.011
RhoGEF2	CG9635 gene product from transcript CG9635-RF	0.011
hrg	hiiragi	0.010
CG6051	CG6051 gene product from transcript CG6051-RB	0.010
Mlc2	Myosin light chain 2	0.010
Xbp1	X box binding protein-1	0.010
tomosyn	CG17762 gene product from transcript CG17762-RB	0.010
CG8709	CG8709 gene product from transcript CG8709-RK	0.010
chico	CG5686 gene product from transcript CG5686-RB	0.010